This document discusses the roles and responsibilities of key positions within UK establishments conducting research on animals. It describes the Named Person Responsible for Compliance (NPRC), now called the Procedure Establishment Licence Holder (PEL), who is responsible for ensuring compliance with the licence conditions. It also outlines the roles of the Named Veterinary Surgeon (NVS), Named Animal Care and Welfare Officer (NACWO), Named Information Officer (NIO), and Named Training and Competency Officer (NTCO), and their responsibilities for overseeing animal welfare, disseminating information, and ensuring staff training.