A 1 year old infant was brought to us with
symptoms of bilious vomiting and abdominal pain. A plain abdominal x ray revealed presence of multiple radio opaque foreign bodies adherent to each other, lying in the small bowel. This raised the
suspicion of accidental ingestion of multiple magnets, which was
confirmed on detailed interrogation of the parents. An exploratory
laparotomy revealed volvulus with pressure necrosis causing multiple perforations of the small bowel, for which a bowel resection
with anastomosis and a loop ileostomy was performed, also all the
magnetic beads were removed intact. The stoma was reversed after
4 weeks. At follow up the child has grown well with no residual
complaints.
Halterman technique for the treatment of ectopically erupting permanent first...iosrjce
This document describes a case study of using the Halterman technique to successfully treat an ectopically erupting permanent first molar within 2 months. The Halterman appliance consists of a band placed on the adjacent primary molar with a wire and distal hook, and an elastic chain placed between the hook and a button bonded to the permanent molar to apply a distal force. The case involved a 5-year-old girl whose left maxillary first permanent molar was ectopically erupting. A radiograph confirmed mesial eruption and resorption of the primary molar. The Halterman appliance was placed and corrected the impaction within 6 weeks, demonstrating the benefits of this technique over other traditional treatments for
Halterman technique for the treatment of ectopically erupting permanent first...Abu-Hussein Muhamad
Tooth eruption is a process whereby the forming tooth migrates from its intraosseous location in the jaw to its functional position within the oral cavity. Ectopic eruption is one of the problems that arise during the transitional dentition period. In this report, the ectopic eruption case was successfully treated with with Halterman type appliance in 2 months. This case report demonstrates that a could with Halterman type appliance provide many benefits over other traditional treatment modalities and thus could be used for correcting ectopic eruption at an early age. Keywords: Ectopic eruption, permanent maxillary first molar, Halterman Appliance
This document describes a case study of a 29 day old infant with a large facial hemangioma involving the right cheek and eyelids, causing recurrent bleeding and an inability to open the right eye. After 4 weeks of treatment with oral propranolol at a dose of 2 mg/kg/day, the hemangioma rapidly regressed, bleeding ceased, and the infant could open the eye. The document concludes that propranolol is a safe and effective first-line treatment for large hemangiomas that pose risks like visual disruption or bleeding in infants.
This study analyzed 52 pediatric patients who underwent intestinal resection over a 10-year period at a hospital in Nigeria. The most common indication for resection was gangrenous or irreducible intussusception (28 cases, 53.8%). Other common reasons included strangulated hernia (7 cases) and typhoid intestinal perforation (6 cases). Most patients were infants under 1 year old. Complications occurred in 38.4% of patients, most commonly surgical site infection. The mortality rate was 15.4%. The study concluded that late presentation and lack of awareness contributed significantly to the high number of intestinal resections required in this patient population.
This study describes 66 eruption cyst cases in 53 pediatric patients seen at 3 dental centers in Turkey between 2014-2015. The average patient age was 5.4 years. More than half of the cysts were located in the maxilla and most commonly associated with the maxillary first primary molars. Multiple cysts occurred in 13 patients. The majority of cysts (86.8%) were asymptomatic and required no treatment, allowing the teeth to erupt spontaneously in 2 months on average. For the 7 symptomatic cysts that caused pain, surgical excision was performed to drain the cysts' contents and facilitate tooth eruption within weeks.
Research article no needle no suture vmmcDeepak Kabbur
This study evaluated a new single-visit adult male circumcision technique called Unicirc that uses a disposable plastic instrument and tissue adhesive. In a trial of 110 men across 3 sites in South Africa, the procedure took a median of 9 minutes with minimal blood loss and pain. There was a 6.3% rate of moderate complications like bleeding and infection but no serious adverse events. Nearly all wounds were fully healed by 4 weeks with high patient satisfaction and excellent cosmetic results, demonstrating the potential for this technique to safely scale up circumcision programs with one visit and without injections.
Neurodevelopmental impacts of prenatal drinking water exposure to manganese a...Melissa Miller
The document discusses neurodevelopmental impacts of prenatal exposure to manganese and other metals through drinking water. It reviews research showing an association between manganese exposure and neurodevelopmental deficits in young children. There are also large gaps in research that need to be addressed. The aim is to examine if children in Holliston, Massachusetts are exposed to harmful chemicals that could lead to adverse health effects, focusing on impacts of metals like manganese on children from in utero to age 10. Biomarkers are discussed that could help measure exposures and impacts.
Background: Sigmoid Volvulus is the third most common cause of colonic obstruction and accounts for
2-4% of intestinal obstructions. A variety of abdominal and functional factors contribute to the development of sigmoid
volvulus. The progression of pathology is extremely rapid. Hence, understanding these factors enables early diagnosis
and prompt surgical intervention. Aims: 20 cases of surgically treated sigmoid volvulus were studied retrospectively
to identify and evaluate various factors causing morbidity and mortality in these patients. Results: The condition was
commonly seen in males, especially those who were institutionalized and were using laxatives for over 5 years. The
mean age was 65.2 years. Co-morbidities were a common accompaniment. 13 patients had diabetes, 12 patients had
hypertension, 2 patients had ischemic heart disease and 9 patients had the neurological disease (Parkinson’s disease).
6 patients had single co-morbidity, 13 patients had 2 co-morbidities and 1 patient had 3 co-morbidities. A plain X-ray
of the abdomen was diagnostic in all cases. The mean time interval from the onset of symptoms to hospital admission
was 8.1 hours, the time interval from hospital admission to confirmation of diagnosis was 2.1 hours. The mean time
interval from diagnosis to surgical intervention was 3.2 hours. The surgical options exercised were resection anastomosis
with a proximal diversion in 13 patients, Hartmann’s procedure in 6 patients, and primary resection anastomosis in
1 patient. Post-operative complications included ileus in 16 patients, stomal dysfunction in 4 patients, and surgical
infections in 10 patients. The mean duration of stay in hospital ranged from 7-13 days. Only 1 patient who had 2
co-morbidities developed complications and succumbed. Conclusion: Prompt diagnosis, optimization of haemodynamic
status including co-morbidities is essential before contemplating surgical intervention. Resection anastomosis with a
proximal diverting stoma is best suited for patients who have not developed a colonic perforation whereas Hartmann’s
procedure is indicated in patients presented with perforative peritonitis.
Halterman technique for the treatment of ectopically erupting permanent first...iosrjce
This document describes a case study of using the Halterman technique to successfully treat an ectopically erupting permanent first molar within 2 months. The Halterman appliance consists of a band placed on the adjacent primary molar with a wire and distal hook, and an elastic chain placed between the hook and a button bonded to the permanent molar to apply a distal force. The case involved a 5-year-old girl whose left maxillary first permanent molar was ectopically erupting. A radiograph confirmed mesial eruption and resorption of the primary molar. The Halterman appliance was placed and corrected the impaction within 6 weeks, demonstrating the benefits of this technique over other traditional treatments for
Halterman technique for the treatment of ectopically erupting permanent first...Abu-Hussein Muhamad
Tooth eruption is a process whereby the forming tooth migrates from its intraosseous location in the jaw to its functional position within the oral cavity. Ectopic eruption is one of the problems that arise during the transitional dentition period. In this report, the ectopic eruption case was successfully treated with with Halterman type appliance in 2 months. This case report demonstrates that a could with Halterman type appliance provide many benefits over other traditional treatment modalities and thus could be used for correcting ectopic eruption at an early age. Keywords: Ectopic eruption, permanent maxillary first molar, Halterman Appliance
This document describes a case study of a 29 day old infant with a large facial hemangioma involving the right cheek and eyelids, causing recurrent bleeding and an inability to open the right eye. After 4 weeks of treatment with oral propranolol at a dose of 2 mg/kg/day, the hemangioma rapidly regressed, bleeding ceased, and the infant could open the eye. The document concludes that propranolol is a safe and effective first-line treatment for large hemangiomas that pose risks like visual disruption or bleeding in infants.
This study analyzed 52 pediatric patients who underwent intestinal resection over a 10-year period at a hospital in Nigeria. The most common indication for resection was gangrenous or irreducible intussusception (28 cases, 53.8%). Other common reasons included strangulated hernia (7 cases) and typhoid intestinal perforation (6 cases). Most patients were infants under 1 year old. Complications occurred in 38.4% of patients, most commonly surgical site infection. The mortality rate was 15.4%. The study concluded that late presentation and lack of awareness contributed significantly to the high number of intestinal resections required in this patient population.
This study describes 66 eruption cyst cases in 53 pediatric patients seen at 3 dental centers in Turkey between 2014-2015. The average patient age was 5.4 years. More than half of the cysts were located in the maxilla and most commonly associated with the maxillary first primary molars. Multiple cysts occurred in 13 patients. The majority of cysts (86.8%) were asymptomatic and required no treatment, allowing the teeth to erupt spontaneously in 2 months on average. For the 7 symptomatic cysts that caused pain, surgical excision was performed to drain the cysts' contents and facilitate tooth eruption within weeks.
Research article no needle no suture vmmcDeepak Kabbur
This study evaluated a new single-visit adult male circumcision technique called Unicirc that uses a disposable plastic instrument and tissue adhesive. In a trial of 110 men across 3 sites in South Africa, the procedure took a median of 9 minutes with minimal blood loss and pain. There was a 6.3% rate of moderate complications like bleeding and infection but no serious adverse events. Nearly all wounds were fully healed by 4 weeks with high patient satisfaction and excellent cosmetic results, demonstrating the potential for this technique to safely scale up circumcision programs with one visit and without injections.
Neurodevelopmental impacts of prenatal drinking water exposure to manganese a...Melissa Miller
The document discusses neurodevelopmental impacts of prenatal exposure to manganese and other metals through drinking water. It reviews research showing an association between manganese exposure and neurodevelopmental deficits in young children. There are also large gaps in research that need to be addressed. The aim is to examine if children in Holliston, Massachusetts are exposed to harmful chemicals that could lead to adverse health effects, focusing on impacts of metals like manganese on children from in utero to age 10. Biomarkers are discussed that could help measure exposures and impacts.
Background: Sigmoid Volvulus is the third most common cause of colonic obstruction and accounts for
2-4% of intestinal obstructions. A variety of abdominal and functional factors contribute to the development of sigmoid
volvulus. The progression of pathology is extremely rapid. Hence, understanding these factors enables early diagnosis
and prompt surgical intervention. Aims: 20 cases of surgically treated sigmoid volvulus were studied retrospectively
to identify and evaluate various factors causing morbidity and mortality in these patients. Results: The condition was
commonly seen in males, especially those who were institutionalized and were using laxatives for over 5 years. The
mean age was 65.2 years. Co-morbidities were a common accompaniment. 13 patients had diabetes, 12 patients had
hypertension, 2 patients had ischemic heart disease and 9 patients had the neurological disease (Parkinson’s disease).
6 patients had single co-morbidity, 13 patients had 2 co-morbidities and 1 patient had 3 co-morbidities. A plain X-ray
of the abdomen was diagnostic in all cases. The mean time interval from the onset of symptoms to hospital admission
was 8.1 hours, the time interval from hospital admission to confirmation of diagnosis was 2.1 hours. The mean time
interval from diagnosis to surgical intervention was 3.2 hours. The surgical options exercised were resection anastomosis
with a proximal diversion in 13 patients, Hartmann’s procedure in 6 patients, and primary resection anastomosis in
1 patient. Post-operative complications included ileus in 16 patients, stomal dysfunction in 4 patients, and surgical
infections in 10 patients. The mean duration of stay in hospital ranged from 7-13 days. Only 1 patient who had 2
co-morbidities developed complications and succumbed. Conclusion: Prompt diagnosis, optimization of haemodynamic
status including co-morbidities is essential before contemplating surgical intervention. Resection anastomosis with a
proximal diverting stoma is best suited for patients who have not developed a colonic perforation whereas Hartmann’s
procedure is indicated in patients presented with perforative peritonitis.
This document describes a study conducted to assess the prevalence of scabies in an orphanage in rural Maharashtra, India and conduct mass treatment. Researchers examined all 50 children and found 41 (82%) had scabies. They provided a health education session and mass treatment for all children and caretakers using 25% benzyl benzoate lotion. Symptoms reduced in 36 children within a week and no cases of relapse were found after 6 weeks of follow up and re-treatment. The study demonstrated that mass treatment along with health education and environmental measures can effectively manage scabies in institutional settings.
This study summarizes the diagnosis and management of 26 cases of recurrent tracheoesophageal fistulas over 27 years. The average gestational age and birth weight of patients who developed recurrent fistulas was lower than typical. Most recurrent fistulas were discovered due to respiratory or feeding symptoms and were diagnosed via contrast study, which revealed the fistula in over 90% of cases. Repairs involved sharply separating the trachea and esophagus and placing tissue like pericardium between the suture lines. Post-operative complications occurred in about 30% of patients, but long-term follow-up showed that over 80% took full nutrition by mouth.
Sovio Et Al Association Between Common Variation In The Fto Locus And Changes...Ulla Sovio
This study analyzed the association between variation at the FTO locus and body mass index (BMI) from infancy to late childhood using data from 8 cohorts. They found that carriers of minor alleles at the FTO locus had lower BMI in infancy, earlier adiposity rebound, and higher BMI later in childhood. The results suggest that genetic variation at the FTO locus is associated with shifts in the timing of developmental milestones like adiposity rebound, rather than just a global increase in BMI. These shifts may have implications for later life metabolic health risk.
This research article describes a study of 127 premature infants diagnosed with necrotizing enterocolitis (NEC) who were treated with either medical or surgical interventions. 88 infants were treated medically, with 54 responding well and 34 requiring laparoscopy. 39 infants underwent emergency surgery. Overall, medical treatment had a 61.4% success rate and lower mortality and morbidity compared to surgical treatment. For infants not responding to medical care, bedside laparoscopy provided diagnostic and therapeutic benefits and reduced the need for emergency surgery in some cases. The study aims to outline treatment approaches and outcomes for NEC to improve management of this serious condition in preterm infants.
JBry The Difference Between Physician Lit ReviewJessica Bryan
Three studies found that physicians were more likely than nurses to have pathogenic bacteria on their stethoscopes. Questionnaires in these studies revealed that most physicians did not clean their stethoscope after each use, unlike nurses who reported cleaning after each use. However, one study found no significant difference in contamination between physicians and nurses. Overall, stethoscopes were shown to be a vector for spreading bacteria like MRSA and E. coli from healthcare workers to immunocompromised patients. More emphasis on stethoscope disinfection education and practices is still needed.
Instrumental esophageal perforation a case seriesAbdulsalam Taha
1) The document describes three cases of instrumental esophageal perforation that were treated surgically.
2) The first case involved a 4-year-old girl who developed an empyema after multiple esophageal dilatation sessions for a corrosive stricture, and ultimately underwent gastric pull-up surgery.
3) The second case was a 54-year-old man who experienced an intraoperative perforation during rigid esophagoscopy that was immediately repaired via thoracotomy.
4) The third case was a 24-year-old man who perforated during balloon dilatation for achalasia and required an emergency esophagectomy.
This document summarizes a research proposal that aims to test the hypothesis that childhood vaccinations cause autism. The study would examine mercury levels in the urine of children at different age groups and time intervals following the MMR vaccination, to determine if higher mercury is associated with autism. The proposal provides background on autism rates increasing, the discredited Wakefield study linking MMR and autism, and reviews previous studies on thimerosal and mercury that both support and contradict the hypothesized link to vaccinations. The proposed methodology would collect urine samples from 18 children divided into age groups around the time of first MMR vaccination, to measure mercury levels at different time points following vaccination.
A clinical study of intussusception in childreniosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
This study evaluated complications in 315 boys who underwent ritual circumcision at a pediatric surgical department between 1996-2003. The overall complication rate was found to be 5.1%, including incomplete circumcisions requiring re-surgery, fibrotic phimosis requiring re-surgery, and meatal stenosis requiring meatotomy. Acute complications included superficial skin infections and prolonged stay or re-admissions for bleeding. Late complications occurred in 2.2% over 8-15 years of follow up. While no major complications occurred, the rates found support informing parents that risks exist and benefits may not outweigh risks for all families. Maintaining high surgical standards can help reduce complication risks when the procedure is performed.
This document presents 5 cases of rare multiple primary neuroblastomas in children. All 5 patients were boys aged 2 months to 4 years who were treated with surgery. Four also received chemotherapy and one received radiotherapy. With treatment, all 5 patients survived and were disease-free for 14 to 32 years of follow up. The cases suggest that diverse tumor differentiation leads to restricted growth and maturation, contributing to the excellent long-term prognosis seen in these rare cases of multiple primary neuroblastomas.
Fetal megacystis - more than luto - Bàng quang lớn ở thai nhi LUTOVõ Tá Sơn
This study analyzed 541 pregnancies with fetal megacystis (enlarged bladder) referred to fetal medicine units in the Netherlands between 2000-2015. The study found that in 67% of cases, megacystis was isolated or accompanied only by signs of lower urinary tract obstruction. In the remaining 33% of cases, megacystis was associated with other structural abnormalities. The most common associated findings were increased nuchal translucency (22%), single umbilical artery (10%), and cardiac defects (10%). The study provides an overview of genetic syndromes, chromosomal abnormalities, and developmental disturbances that can present with fetal megacystis, in order to improve counseling and management of these complex cases
Assessment of Ureteroscopy During Pregnancy.docx4934bk
Ureteroscopy can be performed safely during pregnancy to diagnose and treat ureteral stones. The summary is:
1) Ureteroscopy allows direct visualization of the ureter and extraction or fragmentation of stones without the risks of radiation exposure, as compared to other imaging modalities.
2) In a study of 15 pregnant patients who underwent ureteroscopy, stones were successfully removed or fragmented and all pregnancies resulted in full-term deliveries without complications.
3) Ureteroscopy during pregnancy can be performed safely under sedation rather than general anesthesia using thin ureteroscopes, with close obstetric monitoring.
perineal outcome after restrictive use of episiotomyarbin joshi
This study evaluated perineal outcomes in primi-gravidas after restrictive use of episiotomy in Nepal. The episiotomy rate was 22% and the majority (43.2%) experienced first degree tears. Only one woman (1.4%) experienced a third degree tear, with no long-term complications. Having a baby weighing 2.5kg or more significantly increased mean tear length and nearly doubled the risk of a second or third degree tear. The restrictive episiotomy protocol was successfully implemented with no significant complications observed.
2.Ismail Yazdi anda Amir Hossein Fakhraee Congenital Fusion of Maxilla and M...MohammedAbdulhammed
This case report describes a rare case of congenital fusion of the maxilla and mandible (bony syngnathia) in a newborn female with no other oral anomalies. Physical examination revealed complete adhesion of the jaws, preventing opening of the mouth. Surgical division of the bony fusion via an intraoral approach allowed opening of the mouth and normal feeding. The infant was discharged but later died of pneumonia at 7 months of age. Bony syngnathia is extremely rare and usually seen with other oral anomalies; this case presented an isolated occurrence of the condition.
A 35-day-old female infant presented with incessant cry and with an antenatal diagnosis of ovarian cyst. On evaluation and laparotomy, she was found to have a huge ovarian cyst with torsion and gangrene, which was excised successfully. This is being presented to highlight the possibility of early torsion and gangrene with antenatally detected ovarian cysts and the successful management of one such case.
Managment Of Long Term Care In Era Covid-19komalicarol
COVID-19 gives the chance to address long-term care categories
that are sometimes disregarded and undervalued, such as nursing
and residential homes, as well as homecare. Each method of delivering long-term care must meet the highest possible standards
of ongoing care and quality of life. More study and evaluation are
needed to aid decision-making and policy-making, particularly on
the cost-effectiveness and cost-quality elements for each country,
region, or system.
Renal failure and Quality ofLlife Indicators in Kidney Transplantationkomalicarol
This article discusses quality of life indicators for patients undergoing kidney transplantation. It reviews several tools used to measure quality of life, including the SF-36, EQ-5D, and KDQOL questionnaires. Overall quality of life is generally improved after a successful kidney transplant compared to dialysis. However, factors like side effects of immunosuppressive drugs and the risk of rejection can still impact quality of life. The article concludes that while transplantation is associated with lower mortality and better quality of life than long-term dialysis, certain patient and treatment factors must be considered when evaluating individual quality of life outcomes.
A case of childhood Burkitt's lymphoma with gingival swelling as the first sy...komalicarol
This case report describes a 4-year-old child who presented with gingival swelling as the initial symptom of Burkitt's lymphoma. The child was eventually diagnosed with stage IV Burkitt's lymphoma/leukemia based on bone marrow and genetic testing. After initial chemotherapy, the gingival swelling and right cheek swelling recurred, indicating disease recurrence. The child received further chemotherapy but ultimately passed away half a year later. This case highlights that gingival swelling can be an early oral symptom of systemic disease like Burkitt's lymphoma. Dentists and oral physicians play an important role in identifying signs of systemic conditions through oral examinations.
Neuropsychiatric Profiles of Brivaracetam: A Literature Reviewkomalicarol
Anti-seizure medications (ASMs) can cause cognitive or behavioral adverse drug reactions, which is a significant consideration
when selecting an appropriate ASM. Brivaracetam (BRV) is a
newer synaptic vesicle protein 2A ligand, which is expected to
have less neuropsychiatric adverse effects due to its mechanism of
action. To understand the impact of BRV on cognition and behavior compared with other ASMs, we conducted literatures searching
from PubMed and MEDLINE databases. After the screening process, a total of two animal studies, one randomized controlled trial, one pooled-analysis of clinical trials, one controlled study and
nine observational studies were included. Animal studies showed
that BRV did not worsen cognition or behavior performance in rodents. Human studies showed that BRV had less cognitive adverse
events compared with other second or third generation ASMs. In
addition, currently available evidence suggests that behavioral disturbance is less common with BRV compared with levetiracetam.
This review revealed that BRV has a limited impact on cognition
and behavior. For patients who are intolerant to levetiracetam
and have levetiracetam-related behavioral side effects, switching
to BRV could be beneficial. However, the heterogeneity between
studies makes the quality of the evidence weak and further trials
are needed to confirm the findings.
Clinical and evolutionary features of SARS CoV-2 infection (COVID-19) in chil...komalicarol
Starting with December 2019 the medical world has faced a
new challenge as a consequence of a new type of coronavirus-2019-nCoV, similar to several familiar strains that determine
a comparable symptomatology (SARS- severe acute respiratory syndrome, MERS- Middle East severe acute respiratory syndrome), subsequently named SARS CoV-2, while the disease it
causes- COVID-19. The virus is of animal origin and through an
intermediate host (probably also a mammal) it suffered genetic
changes thus acquiring human cells receptors. In consequence,
SARS CoV-2 virus affects both children and even more frequently where it determines more severe clinical forms of disease. In
children, COVID-19 has various clinical forms, from asymptomatic ones to severe ones, complicated by multisystem inflammatory
syndrome (MIS-C Multisystem Inflammatory Syndrome – Child
or PIMS - TS (Paediatric Multisystem Inflammatory Syndrome
temporally associated with COVID-19) that sometimes can lead
to death
More Related Content
Similar to Fatal attraction: A case of multiple magnet ingestion in an infant
This document describes a study conducted to assess the prevalence of scabies in an orphanage in rural Maharashtra, India and conduct mass treatment. Researchers examined all 50 children and found 41 (82%) had scabies. They provided a health education session and mass treatment for all children and caretakers using 25% benzyl benzoate lotion. Symptoms reduced in 36 children within a week and no cases of relapse were found after 6 weeks of follow up and re-treatment. The study demonstrated that mass treatment along with health education and environmental measures can effectively manage scabies in institutional settings.
This study summarizes the diagnosis and management of 26 cases of recurrent tracheoesophageal fistulas over 27 years. The average gestational age and birth weight of patients who developed recurrent fistulas was lower than typical. Most recurrent fistulas were discovered due to respiratory or feeding symptoms and were diagnosed via contrast study, which revealed the fistula in over 90% of cases. Repairs involved sharply separating the trachea and esophagus and placing tissue like pericardium between the suture lines. Post-operative complications occurred in about 30% of patients, but long-term follow-up showed that over 80% took full nutrition by mouth.
Sovio Et Al Association Between Common Variation In The Fto Locus And Changes...Ulla Sovio
This study analyzed the association between variation at the FTO locus and body mass index (BMI) from infancy to late childhood using data from 8 cohorts. They found that carriers of minor alleles at the FTO locus had lower BMI in infancy, earlier adiposity rebound, and higher BMI later in childhood. The results suggest that genetic variation at the FTO locus is associated with shifts in the timing of developmental milestones like adiposity rebound, rather than just a global increase in BMI. These shifts may have implications for later life metabolic health risk.
This research article describes a study of 127 premature infants diagnosed with necrotizing enterocolitis (NEC) who were treated with either medical or surgical interventions. 88 infants were treated medically, with 54 responding well and 34 requiring laparoscopy. 39 infants underwent emergency surgery. Overall, medical treatment had a 61.4% success rate and lower mortality and morbidity compared to surgical treatment. For infants not responding to medical care, bedside laparoscopy provided diagnostic and therapeutic benefits and reduced the need for emergency surgery in some cases. The study aims to outline treatment approaches and outcomes for NEC to improve management of this serious condition in preterm infants.
JBry The Difference Between Physician Lit ReviewJessica Bryan
Three studies found that physicians were more likely than nurses to have pathogenic bacteria on their stethoscopes. Questionnaires in these studies revealed that most physicians did not clean their stethoscope after each use, unlike nurses who reported cleaning after each use. However, one study found no significant difference in contamination between physicians and nurses. Overall, stethoscopes were shown to be a vector for spreading bacteria like MRSA and E. coli from healthcare workers to immunocompromised patients. More emphasis on stethoscope disinfection education and practices is still needed.
Instrumental esophageal perforation a case seriesAbdulsalam Taha
1) The document describes three cases of instrumental esophageal perforation that were treated surgically.
2) The first case involved a 4-year-old girl who developed an empyema after multiple esophageal dilatation sessions for a corrosive stricture, and ultimately underwent gastric pull-up surgery.
3) The second case was a 54-year-old man who experienced an intraoperative perforation during rigid esophagoscopy that was immediately repaired via thoracotomy.
4) The third case was a 24-year-old man who perforated during balloon dilatation for achalasia and required an emergency esophagectomy.
This document summarizes a research proposal that aims to test the hypothesis that childhood vaccinations cause autism. The study would examine mercury levels in the urine of children at different age groups and time intervals following the MMR vaccination, to determine if higher mercury is associated with autism. The proposal provides background on autism rates increasing, the discredited Wakefield study linking MMR and autism, and reviews previous studies on thimerosal and mercury that both support and contradict the hypothesized link to vaccinations. The proposed methodology would collect urine samples from 18 children divided into age groups around the time of first MMR vaccination, to measure mercury levels at different time points following vaccination.
A clinical study of intussusception in childreniosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
This study evaluated complications in 315 boys who underwent ritual circumcision at a pediatric surgical department between 1996-2003. The overall complication rate was found to be 5.1%, including incomplete circumcisions requiring re-surgery, fibrotic phimosis requiring re-surgery, and meatal stenosis requiring meatotomy. Acute complications included superficial skin infections and prolonged stay or re-admissions for bleeding. Late complications occurred in 2.2% over 8-15 years of follow up. While no major complications occurred, the rates found support informing parents that risks exist and benefits may not outweigh risks for all families. Maintaining high surgical standards can help reduce complication risks when the procedure is performed.
This document presents 5 cases of rare multiple primary neuroblastomas in children. All 5 patients were boys aged 2 months to 4 years who were treated with surgery. Four also received chemotherapy and one received radiotherapy. With treatment, all 5 patients survived and were disease-free for 14 to 32 years of follow up. The cases suggest that diverse tumor differentiation leads to restricted growth and maturation, contributing to the excellent long-term prognosis seen in these rare cases of multiple primary neuroblastomas.
Fetal megacystis - more than luto - Bàng quang lớn ở thai nhi LUTOVõ Tá Sơn
This study analyzed 541 pregnancies with fetal megacystis (enlarged bladder) referred to fetal medicine units in the Netherlands between 2000-2015. The study found that in 67% of cases, megacystis was isolated or accompanied only by signs of lower urinary tract obstruction. In the remaining 33% of cases, megacystis was associated with other structural abnormalities. The most common associated findings were increased nuchal translucency (22%), single umbilical artery (10%), and cardiac defects (10%). The study provides an overview of genetic syndromes, chromosomal abnormalities, and developmental disturbances that can present with fetal megacystis, in order to improve counseling and management of these complex cases
Assessment of Ureteroscopy During Pregnancy.docx4934bk
Ureteroscopy can be performed safely during pregnancy to diagnose and treat ureteral stones. The summary is:
1) Ureteroscopy allows direct visualization of the ureter and extraction or fragmentation of stones without the risks of radiation exposure, as compared to other imaging modalities.
2) In a study of 15 pregnant patients who underwent ureteroscopy, stones were successfully removed or fragmented and all pregnancies resulted in full-term deliveries without complications.
3) Ureteroscopy during pregnancy can be performed safely under sedation rather than general anesthesia using thin ureteroscopes, with close obstetric monitoring.
perineal outcome after restrictive use of episiotomyarbin joshi
This study evaluated perineal outcomes in primi-gravidas after restrictive use of episiotomy in Nepal. The episiotomy rate was 22% and the majority (43.2%) experienced first degree tears. Only one woman (1.4%) experienced a third degree tear, with no long-term complications. Having a baby weighing 2.5kg or more significantly increased mean tear length and nearly doubled the risk of a second or third degree tear. The restrictive episiotomy protocol was successfully implemented with no significant complications observed.
2.Ismail Yazdi anda Amir Hossein Fakhraee Congenital Fusion of Maxilla and M...MohammedAbdulhammed
This case report describes a rare case of congenital fusion of the maxilla and mandible (bony syngnathia) in a newborn female with no other oral anomalies. Physical examination revealed complete adhesion of the jaws, preventing opening of the mouth. Surgical division of the bony fusion via an intraoral approach allowed opening of the mouth and normal feeding. The infant was discharged but later died of pneumonia at 7 months of age. Bony syngnathia is extremely rare and usually seen with other oral anomalies; this case presented an isolated occurrence of the condition.
A 35-day-old female infant presented with incessant cry and with an antenatal diagnosis of ovarian cyst. On evaluation and laparotomy, she was found to have a huge ovarian cyst with torsion and gangrene, which was excised successfully. This is being presented to highlight the possibility of early torsion and gangrene with antenatally detected ovarian cysts and the successful management of one such case.
Managment Of Long Term Care In Era Covid-19komalicarol
COVID-19 gives the chance to address long-term care categories
that are sometimes disregarded and undervalued, such as nursing
and residential homes, as well as homecare. Each method of delivering long-term care must meet the highest possible standards
of ongoing care and quality of life. More study and evaluation are
needed to aid decision-making and policy-making, particularly on
the cost-effectiveness and cost-quality elements for each country,
region, or system.
Renal failure and Quality ofLlife Indicators in Kidney Transplantationkomalicarol
This article discusses quality of life indicators for patients undergoing kidney transplantation. It reviews several tools used to measure quality of life, including the SF-36, EQ-5D, and KDQOL questionnaires. Overall quality of life is generally improved after a successful kidney transplant compared to dialysis. However, factors like side effects of immunosuppressive drugs and the risk of rejection can still impact quality of life. The article concludes that while transplantation is associated with lower mortality and better quality of life than long-term dialysis, certain patient and treatment factors must be considered when evaluating individual quality of life outcomes.
A case of childhood Burkitt's lymphoma with gingival swelling as the first sy...komalicarol
This case report describes a 4-year-old child who presented with gingival swelling as the initial symptom of Burkitt's lymphoma. The child was eventually diagnosed with stage IV Burkitt's lymphoma/leukemia based on bone marrow and genetic testing. After initial chemotherapy, the gingival swelling and right cheek swelling recurred, indicating disease recurrence. The child received further chemotherapy but ultimately passed away half a year later. This case highlights that gingival swelling can be an early oral symptom of systemic disease like Burkitt's lymphoma. Dentists and oral physicians play an important role in identifying signs of systemic conditions through oral examinations.
Neuropsychiatric Profiles of Brivaracetam: A Literature Reviewkomalicarol
Anti-seizure medications (ASMs) can cause cognitive or behavioral adverse drug reactions, which is a significant consideration
when selecting an appropriate ASM. Brivaracetam (BRV) is a
newer synaptic vesicle protein 2A ligand, which is expected to
have less neuropsychiatric adverse effects due to its mechanism of
action. To understand the impact of BRV on cognition and behavior compared with other ASMs, we conducted literatures searching
from PubMed and MEDLINE databases. After the screening process, a total of two animal studies, one randomized controlled trial, one pooled-analysis of clinical trials, one controlled study and
nine observational studies were included. Animal studies showed
that BRV did not worsen cognition or behavior performance in rodents. Human studies showed that BRV had less cognitive adverse
events compared with other second or third generation ASMs. In
addition, currently available evidence suggests that behavioral disturbance is less common with BRV compared with levetiracetam.
This review revealed that BRV has a limited impact on cognition
and behavior. For patients who are intolerant to levetiracetam
and have levetiracetam-related behavioral side effects, switching
to BRV could be beneficial. However, the heterogeneity between
studies makes the quality of the evidence weak and further trials
are needed to confirm the findings.
Clinical and evolutionary features of SARS CoV-2 infection (COVID-19) in chil...komalicarol
Starting with December 2019 the medical world has faced a
new challenge as a consequence of a new type of coronavirus-2019-nCoV, similar to several familiar strains that determine
a comparable symptomatology (SARS- severe acute respiratory syndrome, MERS- Middle East severe acute respiratory syndrome), subsequently named SARS CoV-2, while the disease it
causes- COVID-19. The virus is of animal origin and through an
intermediate host (probably also a mammal) it suffered genetic
changes thus acquiring human cells receptors. In consequence,
SARS CoV-2 virus affects both children and even more frequently where it determines more severe clinical forms of disease. In
children, COVID-19 has various clinical forms, from asymptomatic ones to severe ones, complicated by multisystem inflammatory
syndrome (MIS-C Multisystem Inflammatory Syndrome – Child
or PIMS - TS (Paediatric Multisystem Inflammatory Syndrome
temporally associated with COVID-19) that sometimes can lead
to death
Viral load and antibody responses in an asymptomatic/minimally symptomatic SA...komalicarol
Asymptomatic patients with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), are silent carriers of the disease. We
aimed to characterize their dynamics of disease occurrence, viral
shedding and antibody responses using a cohort of asymptomatic/
minimally symptomatic patients from Sri Lanka during the first
wave of COVID-19.
Vonlay; A paradigm shift in post endodontic restoration: A case report.komalicarol
Porcelain veneers have long been a popular restorative option that
have evolved into a well- accepted treatment that can be fabricated
in various ways. Onlays are another common treatment modality
used in contemporary dentistry to restore large areas of decay and
to replace old restorations. With the availability of newer highstrength materials such as lithium disilicate and processing technologies like CAD/CAM and heat pressing, dental professionals
are now able to produce highly esthetic, high-strength restorations
that blend seamlessly with the natural dentition while also withstanding posterior occlusal forces. A tooth more complex restoration is required after endodontic treatment when compared to normal tooth restoration, because of factors such as extensive caries,
post-treatment root canal dentin and even the economics condition
of the patient.One such design proposed by Dr.Ronald E Goldstein
is “Veenerlay”or “Vonlay”. Vonlay is a blend of an onlay with an
extended buccal veneer surface for use in premolar region, where
there is sufficient enamel present to bond. This restorative option
requires a much less invasive preparation than a full coverage
crown but provides the same structural benefits. Thus, the aim of
this case report is to present a case of Vonlay following endodontic
treatement of lower mandibular premol
A COVID Journey in Diabetes: T1D Diabetes Patient 44 years - Winning in Insul...komalicarol
Complications of Hypoglycaemia, Hypoglycaemia
and Neuroglycopenia are often encountered by patients treated
with insulin. It is feared by patients and families often leading to
emotional and mental scars and can affect lifestyle and confidence.
Hypoglycaemia can occur in premature babies, persons with hypopituitarism and Addison’s Disease. Low blood glucose can affect
athletes and the elderly leading to falls. Cases are individual and
often difficult for families, clinicians, lawyers and courts to understand.
Loops Around the Heart – A Giant Snakelike Right Coronary Artery Ectasia with...komalicarol
Coronary artery dilatation is an uncommon finding and is incidentally found during diagnostic coronary angiography or at necropsy.
The pathogenesis of dilatation of coronary arteries is still not very
well understood and therapeutic strategies are not clear. It is useful to know the difference between aneurysm and ectasia. In this
report we demonstrate the diagnostic workup of an asymptomatic
patient with a remarkable snakelike dilatation of the right coronary
artery with unique convolute. For the first time we used intracoronary injection and simultaneous echocardiographic visualization
of contrast agent (Sonovue) to proof a fistula to the coronary sinus.
Like our patient, most of the patients are asymptomatic in absence
of coronary artery disease and we decided on a conservative approach because of his very complex anatomy
Skull Metastasis From Papillary Thyroid Carcinoma : Case Report and Literatur...komalicarol
Although papillary thyroid carcinoma is a relatively common form of malignancy, metastatic spread to the skull
is exceptional. Here, we report a case of papillary thyroid carcinoma revealed by frontal skull metastasis.
Diabetes and Covid-19 Pandemic - A T1 Patient Perspective - Derek C Beattykomalicarol
A patient treated and cared for by NHS Scotland and NHS England
the author has in his 44 years T1D Diabetes journey experienced
surgery provided by the NHS by way of Vitrectomy, Ophthalmic
laser and correction, and Orthopedic knee correction following
a balance issue associated with IV antibiotic treatment for Otitis
Externa and Osteomyelitis associated with long term T1 Diabetes
with neuropathy. Interestingly IV antibiotic treatment led to glycemic issues offering explanation as to why on occasion glycaemia
abnormalities can occur with antibiotic treatment for infection.
Growth Charts-Curves of Children's Height - How to Construct Themkomalicarol
A person born in 1990, for example, grew to one year old on his/
her birth day in 1991 and 17 years old in 2007. No one grows
to their 17 or 20 years old instantaneously. It takes a long-capricious time of mental and physical activities to grow. As regards
children’s milk consumption, for example, school lunch programs
were put into in practice on national scale only in the late 1990s.
Those in their late adolescence in 2007 were not the beneficiaries
of free milk, when they were in primary school.
Dermatological health in the COVID-19 erakomalicarol
COVID-19 and its impact on dermatological health was reviewed
from theoretical and statistical frameworks in the present study. A
cross-sectional and retrospective work was documented with a selection of sources indexed to Scopus, considering the period from
2019 to 2022, as well as the search by keywords. Approaches were
discussed in order to outline a comprehensive model that considered the differences between the parties involved, as well as their
relationships in a risk context. The proposal contributes to the state
of the question in terms of the prediction of contingencies derived
from the probability and affectation of dermatological health
The Importance of Framing at the Beginning of an Review Dialoguekomalicarol
Long-term care of patients with chronic conditions in general practice rarely focuses on the treatment process. A specific interaction
tool, the Review Dialogue (RD), has been developed to integrate
patients’ health-related problems/risks as well as coping strategies
and to agree upon shared treatment objectives assuming that periodical RDs will help to achieve them. Initiated by the GP, the RD
changes the role expectations of the patient and doctor. Therefore,
the framing of the encounters is of particular importance.
Early detection of interstitial lung disease in asymptomatic patients with 2-...komalicarol
Pulmonary involvement is a common manifestation of Dermatomyositis (DM), the most frequent histologic pattern being Interstitial Lung Disease (ILD) which is a major contributor to
morbidity and mortality in these patients. Therefore, this disease
should be investigated and it is essential to perform pulmonary
function tests (PFTs) and High-Resolution Computed Tomography
(HRCT) early in the course of the disease to make a definitive
diagnosis. Nowadays, 2-deoxy-2-[18F] fluoro-D-glucose positron
emission tomography/computed tomography
Association between Galectin-3 and oxidative stress parameters with coronary ...komalicarol
Galectin-3 (Gal-3), as a mediator of inflammation and fibrosis, has been reported to be a biomarker of severity in
coronary artery disease (CAD). The study aimed to assess the relationships between coronary artery disease (CAD) and risk factors,
including parameters of oxidative stress in Tunisian patients CAD.
The risks of using 2,4?dinitrophenol (2,4?DNP) as a weight loss agent: a lite...komalicarol
The prevalence of obesity has steadily increased in response to
changes in diet and physical activity patterns over the past 10
years, becoming one of the leading causes of morbidity and mortality worldwide. In addition, the popularity of social networks
has increased social and cultural pressure for the search for the
“perfect body”. These factors result in the search for fast and unconventional methods of weight loss, such as the use of weight
loss accelerating drugs. 2,4-Dinitrophenol (2-4-DNP or DNP) is
an industrial chemical used to lose weight quickly. Due to its great
potential for toxicity, its use has been banned in several countries
since 1938
Height is a measure of consumption that incorporates nutritional needs: When ...komalicarol
This document summarizes research on trends in height among children in Japan and South Korea from the mid-20th century onward. It finds that as the food supply and consumption of animal proteins increased in both countries following World War II and the Korean War, children grew taller. However, Japanese children stopped growing taller in the late 1980s while South Korean children continued increasing in height until the mid-2000s, eventually surpassing Japanese children. The author questions explanations that focus only on differences in ethnicity or animal protein consumption, noting changes in consumption of other nutrients may also play a role.
Successful management of a broken stylet retained in tracheobronchial tree-a ...komalicarol
This case report describes the successful removal of a broken piece of stylet from a patient's right main bronchus during intubation for surgery. During intubation using a video laryngoscope and stylet-guided endotracheal tube, the stylet broke off in the bronchus but was not noticed. Later, a nurse observed the stylet was shorter than expected. Bronchoscopy revealed the broken stylet fragment, which was then extracted without issue. The report discusses the importance of carefully checking equipment before and after intubation procedures to prevent such foreign body issues.
Risk Analysis of Secular Trends for a Later Age at MPV of Weight in an Earthq...komalicarol
The Great East Japan Earthquake occurred in 2011, bringing unprecedented damage to the Tohoku region of Japan. Today, after 11
years, the scars from that tremendous damage remain. The health
damage to young school children has been particularly great. One
may imagine a slowing trend in physical growth from the effects
of that disaster, but no clear findings have been reported.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
low birth weight presentation. Low birth weight (LBW) infant is defined as the one whose birth weight is less than 2500g irrespective of their gestational age. Premature birth and low birth weight(LBW) is still a serious problem in newborn. Causing high morbidity and mortality rate worldwide. The nursing care provide to low birth weight babies is crucial in promoting their overall health and development. Through careful assessment, diagnosis,, planning, and evaluation plays a vital role in ensuring these vulnerable infants receive the specialize care they need. In India every third of the infant weight less than 2500g.
Birth period, socioeconomical status, nutritional and intrauterine environment are the factors influencing low birth weight
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Kosmoderma Academy, a leading institution in the field of dermatology and aesthetics, offers comprehensive courses in cosmetology and trichology. Our specialized courses on PRP (Hair), DR+Growth Factor, GFC, and Qr678 are designed to equip practitioners with advanced skills and knowledge to excel in hair restoration and growth treatments.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
2. http://www.acmcasereport.com/ 2
Volume 7 Issue 6 -2021 Case Report
ly adherent to each other, after the bowel involved was separated
from each other two perforations were noted, i.e., 7 cm and 30 cm
proximal to the ileo cecal junction (Figure 1c). Only 8 magnets
were extracted out, when an on-table fluoroscopy was performed
the remaining 3 magnets were found in the 1st
part of duodenum
which were carefully milked out through the first perforation in the
small bowel. The proximal perforation in the ileum was large, with
extensive serosal tear which warranted resection and anastomosis,
while the distal perforation was converted into a loop ileostomy
due to its proximity to the ileocecal junction. A repeat fluoroscopy
was performed on table to check for any residual magnets. All the
11 magnets were extracted out (Figure 1d).
The post-operative period was uneventful, oral feeds were started
on post-operative day 3 which was progressed to full feeds by day
6. The infant was discharged from the hospital on post-operative
day 7. The stoma reversal was performed 3 weeks later, which was
also uneventful. The child at follow up has grown well with no
residual abdominal complaints.
Figure 1: Infant with multiple magnet ingestion
A: Xray abdomen depicting 11 magnets adherent to each other which are non-mobile and dilatation of proximal bowel loops.
B: Volvulus of the small bowel caused by the magnets, with bluish discoloration of the bowel loops secondary to pressure necrosis.
C: Perforations of the small bowel.
D: All the 11 neodymium magnets ingested extracted out.
4. Discussion
Foreign body ingestion is a common paediatric problem; with
majority been reported in those who are younger than 3 years of
age [3]. Most foreign bodies ingested, pass out without any com-
plications, however a history of possible magnet ingestion should
be treated with more caution, especially amongst children. Tra-
ditional ferrite magnets are large and magnetically weak, and the
earliest case report of bowel perforation following the ingestion
of these ferrite magnet was from Japan in 1995 [4]. However, the
new neodymium iron boron magnets have become smaller, stron-
ger, more prevalent, causing severe damage to the gastrointestinal
tract. Neodymium iron boron magnets are 10-20 times stronger
than traditional ferrite magnets. Neodymium magnets were in-
vented by General Motors and Sumitomo Special Metals in 1982,
and are used in many toys and modern household products [2]. In
2002, McCormick et al reported 24 cases of neodymium magnets
ingestion causing gastro intestinal complications [5]. Complica-
tions tend to occur when these magnets after ingestion attract dif-
ferent bowel loops, trapping them causing ischemia secondary to
pressure necrosis leading to bowel necrosis, volvulus, perforation
and sepsis [6,7].This could have serious lifelong consequences,
including bowel resections and thereby increasing the morbidity
especially amongst children [8].In 2006, the US Consumer Prod-
uct Safety Commission raised the recommended age for magnet-
ic children’s toys from 3 years to 6 years due to increased inci-
dence of ingestion of these magnets and to ensure children’s safety
[9,10]. In a 2012 survey, members of the North American Society
for Paediatric Gastroenterology, Hepatology and Nutrition report-
ed 480 cases of high-powered magnet ingestions in the previous
10 years, 204 of which were in the previous 12 months [11]. We at
our institute have observed a similar trend of increase in the preva-
lence of such cases amongst children, and we feel that a ban on the
sale of such type of toys may help in preventing future incidence
of such cases.
Children usually present with symptoms such as vomiting, abdom-
inal pain, and fever following ingestion of a foreign body [12]. The
difficulty to obtain a precise history of magnet ingestion, which is
common amongst the paediatric population, can lead to substan-
tial delays in diagnosis and management. In our case the parents
did not reveal any history of magnet ingestion initially, only on
detecting a foreign body on imaging, the parents retrospectively
revealed a history of multiple magnet ingestion. There are many
guidelines and algorithms proposed in literature for the manage-
ment of children with magnet ingestions, to avoid delay in their
diagnosis and management especially by primary health care in-
dividuals [1,2,13]. We too have formulated an algorithm for the
management of such cases of magnet ingestion which is simple,
detailed, and self-explanatory (Figure 2). An accurate history, clin-
ical features and an appropriate imaging are the most important, in
the management of such children who have ingested magnets, be
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Volume 7 Issue 6 -2021 Case Report
it single or multiple. If ingestion of a single magnet is suspected
(either in stomach or beyond the stomach) , then the child may be
followed by serial imaging until the magnet is expelled out. Hypo-
thetically, a single magnet especially the neodymium magnets may
be attracted to other metallic objects which are either swallowed or
in contact with the anterior abdominal wall. Thus, the parents are
counselled to avoid clothing with metallic buttons or buckles for
the children. If ingestion of multiple magnets is suspected (either
in the stomach or beyond the stomach), then the management is
more complicated. If the child is symptomatic or asymptomatic
and on serial imaging the magnets appear to be bound together, it
can be inferred that they are anchoring to each other through the
bowel wall, and a perforation is likely to occur. If in the stomach, a
trial with endoscopy or a catheter with magnetic tip for retrieving
the magnet can be attempted, but if failed the child would require
surgical intervention [14, 15]. If passed distal to pylorus, prompt
surgical intervention is required before a complication develops.
In our case as the infant was symptomatic with abdominal pain and
vomiting with the magnets been multiple, we considered surgical
exploration to avoid further complications. If early intervention is
considered extensive bowel resections due to bowel necrosis and
dangers of sepsis can be avoided.
Figure 2: Algorithm for the management of children with magnet ingestion, formulated by the department of pediatric surgery.
5. Conclusion
Primary prevention is the best way to avoid morbidity associat-
ed with multiple magnet ingestion in children, and warning labels
on magnet-based products have been insufficient in avoiding such
cases scenarios. This case illustrates the dangers of multiple neo-
dymium magnet ingestion, and the need for an early surgical in-
tervention based on a simple management algorithm to prevent
morbidity.
References
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Volume 7 Issue 6 -2021 Case Report
12. Miller RS, Willging JP, Rutter MJ, Rookkapan K. Chronic esopha-
geal foreign bodies in pediatric patients: a retrospective review. Int J
Pediatr Otorhinolaryngol. 2004; 68: 265-72.
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