This document outlines Rotary International's 2021-22 presidential initiative to empower girls worldwide through enhancing their safety, health, education, and well-being. It begins by explaining the benefits of empowering girls, such as reducing poverty and increasing economic growth. It then details many challenges girls face, such as sex selection, lack of access to education and healthcare, child marriage, and violence. Finally, it provides suggestions for how Rotary clubs can get involved through local community projects that address challenges faced by girls.