This curriculum vitae outlines the educational and professional background of Emily A. Kelly. She received her Ph.D. in Neuroscience from SUNY Upstate Medical University in 2005 and has since held positions as a postdoctoral research associate and staff scientist at the University of Rochester, where she has conducted research on synaptic plasticity in the visual cortex and amygdala using techniques including two-photon microscopy, immunohistochemistry, and tract tracing in non-human primates. She has also mentored numerous undergraduate and graduate students in neuroscience research.

1. C.V.- Emily A. Kelly- Page 1 of 5
Curriculum Vitae
EMILY A. KELLY
PROFESSIONALADDRESS
Staff Scientist
University of Rochester Medical Center- School of Medicine and Dentistry
Departmentof Neuroscience
601 Elmwood Avenue, Box603, Rochester, New York 14642
(585)275-7952
Emily_Kelly@urmc.rochester.edu
EDUCATION
1998-2005 Ph.D., Neuroscience, SUNYUpstateMedicalUniversity, Syracuse, NY,
1991-1995 B.S., Biology/Psychology, BatesCollege, Lewiston, ME
RESEARCH EXPERIENCE
2015- Staff Scientist, University ofRochester, Rochester NY
Advisor:Dr. Julie L. Fudge
 Analysisof the role of corticotropinreleasing factor (CRF)- mediatedsignaling in the non-human
primate ventralmidbrain.
 Determinationof afferent andefferent projection profiles in the non-humanprimateamygdala
following surgical implementationof tract tracers in the non-humanprimatebrain.
2014-2015 SeniorProjectsResearch Associate, University ofRochester, Rochester NY
Advisor:Dr. Ania K. Majewska
2007-2014 PostdoctoralResearch Associate, University ofRochester, RochesterNY
Advisor:Dr. Ania K. Majewska
 Analysisof dendritic spine structuralchangesin visualcortex duringocular dominanceplasticity
after treatmentwith fluoxetine andin mice with altered protease signaling(tPA and MMP-9 KO)
usingintrinsic signaling and two-photonmicroscopy.
 Analysisof extracellular matrix compositionandprotease activity following monoculardeprivation
in rodent primary visualcortex.
 Analysisof intracellular adhesionmolecule 5 (ICAM-5;Telencephalin) expression using
immunoperoxidasereactivity andelectron microscopy.
 Analysisof the effects of low-dose bisphenol-Aonocular dominanceplasticity in the mouseprimary
visualcortex.
2005-2007 PostdoctoralFellow, University ofRochester, Rochester NY
Advisor:Dr. DavidR. Kornack
 Characterizationof doublecortinpositiveneuronsin a non-neurogenicregionof the adultrodent
brain usingthymidine-analogincorporationandhistochemicalanalysisof developmentalprotein
markers.
 Analysisof Adendo-AssociatedVirus(AAV) serotypes1,2, and8 in adult rodentprogenitorcells
following stereotaxic injection of AAV intolateral ventricle or striatum.
2000-2005 Ph.D. Candidate, SUNYUpstateMedicalUniversity, Syracuse, NY
DissertationProject- Synaptogenesisin BarrelCortexof GAP-43 Deficient Mice
Advisor- Dr. JamesS. McCasland
Analysisof changesin synaptogenicproteinsand postsynapticcell morphology inresponse to
reduced levels of the growthassociated protein, GAP-43 (GAP-43 HZ) in the rodent somatosensory
cortex (barrel cortex).

2. C.V.- Emily A. Kelly- Page 2 of 5
1994-1995 UndergraduateThesis- “TheEffects of Adrenalectomy and Memory Trainingon SubsequentMemory
Deficits”, BatesCollege, Lewiston, ME
Advisor-Dr. JohnE. Kelsey
Performed adrenalectomieson anesthetizedSpragueDawley rats understerile conditions. Ratswere
subjected to workingand spatialmemory tasksto elucidate potential cognitive lossesfollowing
reductionsin glucocorticoid levels. Glucocorticoid reduction hasbeen shown tocause severe
degenerationof the dentategranule cells of the hippocampusresultinginsufficient memory
impairments.
TEACHING AND MENTORINGEXPERIENCE
2006-Present University of Rochester, Rochester, NY
 University of Rochester Science Buddies After SchoolScience Club(2013)- Team Leader. Traveled to
local elementary schoolsand lead hands-onscience activities thatfocused on engagingreal-life
issues;including viral outbreaks, detectingcancer andapplicationsin nanoscience. The goal of this
programis to increase studentknowledgeandinterest in Science, Technology, Engineering, and
Math(STEM).
 Brain Awareness Week (2013-14)- Traveledtomultiple local elementary schools(Grades K-3)to
teach children aboutthe brain. Children rotatedthroughmultiple hand-onactivities- focusingon
touch, vision, balance, taste and smell- and learned where these sensesare received andprocessed
in the humanbrain.
 Graduate StudentResearch Mentor(2007-Present)- Advisedandtrainedgraduate level studentsin
a variety of technical skillsas needed, including histology, molecularbiology preparationsand
microscopic analysis. Guided studentsinindependent-based projects. Graduatestudentswere
mentoredand trained with the goal thatthey wouldmentor in-comingstudentsaswell.
 UndergraduateStudentResearchMentor. (2010-Present)Advisedandtrainedundergraduate
studentin all aspectsof histologicalanalysis- includingimmunocytochemistry, brightfield
microscopy andimage processing. Senior level (University of Rochester) studentsoften aspire
towardsa Distinctionin Research HonorsThesis. Studentsare trained towork independently, to
think critically and troubleshootproblemswhennecessary.
 UndergraduateSummerFellowshipProgramin Visual Sciences. (2008-2013). Mentored, advised
andtrained undergraduatestudentstoperform independentresearch projects. Studentsattended
neuroscience classes andseminars andpresented research material at the endof the session.
Studentswere trainedin all aspects of histological analysis- includingimmunocytochemistry,image
acquisition(confocal andbrightfield microscopy)andimage analysis(Zen 2010, ImageJ). Students
were trained to eventually work independently, tothink critically andtroubleshootproblemswhen
necessary.
 High School BioengineeringSummer Research Program. (2007-2009)Mentoredhighschool
studentsin summerresearch project. Discussed histologicalapproachesand protocoldesign.
 SummerUndergraduateResearch Fellowship(SURF) Program. (2006, 2010-2011) Servedinan
advisory capacity for undergraduatestudentresearchproject. Trained studentsin all aspectsof
histological analysis- includingimmunocytochemistry, fluorescentmicroscopy andimage
processing.
2000- SUNYUpstateMedicalUniversity, Syracuse, NY
 HumanNeuroanatomy. Actedasteaching assistantfor 1st
year medical school course. Duties
included runningsmall groupspecimen analysisandreview of neuroanatomicalstructure and
function.

3. C.V.- Emily A. Kelly- Page 3 of 5
TECHNICAL EXPERIENCE
 Stereotaxic injections of varioustract tracers in the non-humanprimatebrain:involvingaseptic
neurosurgery.
 Two PhotonMicroscopy- foranalysisof dendritic spine morphology andplasticity
 Optical Imaging- assessingtheintrinsic signalfollowing visualstimulationin rodent visualcortex
 In Situ andGel Zymography- foranalysisof MMP andtPA enzymeactivity
 Electron Microscopy- experience in pre-embeddingimmunocytochemistry andsamplepreparation
for electron microscopy;ultramicrotomy andelectron microscopy
 Immunohistochemistry/multi-immunofluorescence, CresylViolet, CytochromeOxidase
Histochemistry
 Gold and Silver Enhancementfor immunohistochemistry
 Small animal transcardialperfusion andbrain extraction
 Freezing Microtomesectioning
 Vibratome Sectioning
 CryostatSectioning
 Confocal Microscopy (Lasersharp2000-2001, BioRad, Fluoview,ZeissLSM):z-seriesimage
acquisitionand analysis(Laserpix Software, MicroBrightField,Fluoview,Zen2010)
 PCRgenotypingandelectrophoretic gels
 Microarray analysis, including micro-dissection, RNAextraction
 Western Blot Analysis
 Sample preparationfor Proteomics analysis
 In situhybridization(includingprobe andprimer design, autoradiography)
 Assisted with IV catheter drug administrationinnon-humanprimate
 Assisted with stereotaxic virus administrationinadult rat brain
 Powerpointpresentationdesign
 Experienced in image processingusing PhotoshopandCanvasprograms
 SpreadsheetanalysisusingMicrosoft Excel and GraphpadPrism
COMMITTEES
2001-2002 President- Graduate Student Association
2000-2001 Treasurer- Graduate StudentAssociation
1999-2000 PresidentNeuroscience JournalClub
SOCIETYMEMBERSHIPS
1999- Society for Neuroscience
1995- Sigma Xi, The Scientific Research Society
SUPPORT
2014 FASEB/MARC ProgramsTravel Award
 Award to attend the 2014 PostdoctoralPreparationInstituteWorkshopinBethesdaMD.
2011-2013 Toxicology Training Grant, NIHfunded, T32 ES 7026-34
 Title: The effects of postnatalBPAexposureon MMP-9 inducedsynapticplasticity in mousevisual
cortex
2010 BurroughsWellcome FundTravel Award #1009101
 ApplyingEnzymeActivity Assaysto Visual Plasticity with Dr. NicholasSeeds
2007-2008 Vision Training Grant, NEI funded, EY013319
 Title: MechanismsofLaminarPlasticity in theVisualSystem

4. C.V.- Emily A. Kelly- Page 4 of 5
PRESENTATIONS
 Kelly, E.A., Rittenhouse, C., Majewska, A.K. (2013)“The effects of postnatalexposureto low-dosebisphenol-A
on ocular dominanceplasticity in the mouseprimary visualcortex”.
AWARDS
 The MacGregor PresentationAward (2013)for bestoverall presentation: Departmentof Environmental
Sciences: Toxicology Training ProgramRetreat.
 The JohnBartlett PosterPresentationAward (2011)for bestposter presentationby a Postdoctoral Fellow.
PUBLICATIONS
Manuscripts
 Fudge, J.L., Kelly, E.A., Pal, R., Bedont, J.L., Park, L., Ho, B. (2017). Beyondtheclassic VTA: extendedamygdala
projections tothe DA-striatal pathsin the primate. Journalof Neuropharmacology. Submitted.
 Sipe, G.O., Lowery, R.L., Tremblay, M.E., Kelly, E.A., Lamantia, C.E., Majewska, A.K. (2016). MicroglialP2Y12 is
necessary for synapticplasticity in mousevisualcortex.
 Kelly, E.A., Russo, A.S., Jackson, C.D., Lamantia, C.E., Majewska, A.K. (2015). Proteolyticregulationofsynaptic
plasticity in the mouseprimary visual cortex: analysisof matrix metalloproteinase 9 deficient mice. FrontCell
Neurosci., Sept22;9:369.
 Kelly, E.A., Opanashuk, L.A., Majewska, A.M. (2014). Theeffects of postnatalexposureto low-dosebisphenol-
A onactivity dependentplasticity in the mouse sensory cortex. Front. Neuroanat. Oct22, 8:117.
 Shapovalov, Y., Zettel, M., Kelly, E.A., Sipe, G.O., Dickerson, I., Brown, E.B., Majewska, A.K. (2014). Fluoxetine
ModulatesBreastCancer Metastasistothe Brain. BMCCancer, Aug 16;14:598.
 Kelly, E. A., Tremblay, M. E., Gahmberg, C. G., Tian, L., Majewska, A. K. (2014)Subcellular localization of
intercellular adhesionmolecule-5 (telencephalin) in the visualcortex is notdevelopmentally regulated in the
absence of matrix metalloproteinase-9. J. Comp. NeurosciFeb15;522 (3): 676-88.
 Kelly, E. A., Tremblay, M. E., Gahmberg, C. G., Tian, L., Majewska, A. K. (2013). Interactionsbetween
intercellular adhesionmolecule-5 positive elements andtheir surroundingsinthe rodent visualcortex.
Communicativeand IntegrativeBiology;Nov 1;6(6):e27315.
 Kelly, E. A. andMajewska, A. K. (2010)Chronicimaging of mousevisual cortex using a thinned-skull
preparation. J Vis Exp. Oct 25;(44).
 Kelly, E. A., Tremblay, M.E., McCaslandJ.S., Majewska, A.K. (2010)PostsynapticDeregulationin GAP-43
HeterozygousMouseBarrel Cortex. CerebralCortex20(7)1696-1707.
 Lowery, R., Zhang, Y., Kelly, E.A., Lamantia, C., Harvey, B., Majewska, A. (2009) Rapid, long-termlabeling of
cells in the developingand adultrodent visualcortex usingdouble-strandedadeno-associatedviralvectors.
Dev Neurobiol69(10)674-88.
ManuscriptsinPreparation
 Kelly, E.A., Fudge, J.L. (2017). Distributionof Corticotropin-ReleasingFactor(CRF) Immunoreactivity inRodent
andNon-humanPrimate:ImplicationstoSignalingin the Ventral Midbrain.

Abstracts
 Fudgelab studentabstracts
 Kelly, E.A., Rittenhouse, C., Majewska, A.K. (2013)The effects of postnatalexposureto low-dosebisphenol-A
on ocular dominanceplasticity in the mouseprimary visualcortex. DepartmentofEnvironmentalScience:
Toxicology Training ProgramRetreat.
 Kelly, E. A., Tremblay, M.-E., Tian, L, Gahmberg, C., Majewska, A.K. (2011)UltrastructuralDistributionof
ICAM-5 (Telencephalin) in mousevisualcortex. University of RochesterNeuroscienceRetreat.

5. C.V.- Emily A. Kelly- Page 5 of 5
 Kelly, E. A., Tremblay, M.-E., Tian, L, Gahmberg, C., Majewska, A.K. (2011)UltrastructuralDistributionof
ICAM-5 (Telencephalin) in mousevisualcortex. Soc. Neurosci. Abstr.
 Kelly, E. A., Tremblay, M.-E., Tian, L, Gahmberg, C., Majewska, A.K. (2011)UltrastructuralRelationship
between ICAM-5 (Telencephalin) labeled dendrites andglial elements in mouse visual cortex. Synapses:From
Moleculesto Circuits and Behaviormeeting.
 Kelly, E. A., Tremblay, M.-E., Tian, L, Gahmberg, C., Majewska, A.K. (2010)UltrastructuralRelationship
between ICAM-5 (Telencephalin) labeled dendrites andglial elements in mouse visualcortex. Soc. Neurosci.
Abstr.
 Kelly, E. A., Majewska, A. (2009)MonocularDeprivationInducesChangesin SynapticStructurein Adult
RodentVisual Cortex following MonocularDeprivation. Soc. Neurosci. Abstr.
 Kelly, E. A., Majewska, A. (2008)Changesin Extracellular Matrix CompositionduringExperience-Dependent
Plasticity in the DevelopingVisual Cortex. Soc. Neurosci. Abstr.
 Kornack, D.R., Kelly, E. A., Shannon, D.E. (2005)PersistentDoublecortinExpressionIdentifies a Novel
NeuronalPopulationinAdult Primate Neocortex. Soc. Neurosci. Abstr.
 Kelly, E. A., McCasland, J.S. (2004)GAP-43 HeterozygousMicefail to ShowNormalSynapticReorganizationin
DevelopingBarrel Cortex. Somatosensory andMotorResearch 21(1):45-64
 Kelly, E. A., McCasland, J. S. (2002)Elevated MetabolismandColocalizationof PostsynapticReceptorsin
Barrel Cortex of GAP-43 HeterozygousMice: Evidence for HomeostaticCompensation. Somatosensory and
MotorResearch 20(1):93-110
 Kelly, E.A., Blue, M. E., McCasland, J. S. (2001)PatternedNMDAR1 immunostaininginmousebarrel cortex
requires GAP-43 expression. Somatosensory and MotorResearch 18(2):150-174.
REFERENCES
Available upon request
 Ania K. Majewska, Ph.D. AssociateProfessor, Departmentof Neurobiology andAnatomy, University of
Rochester Medical Center. Ania_Majewska@urmc.rochester.edu
 DavidR. Kornack, Ph.D. AssociateProfessor, Departmentof Neurobiology and Anatomy, University of
Rochester Medical Center. David_kornack@urmc.rochester.edu
 JamesS. McCasland, Ph.D., Professor, DepartmentofCell andDevelopmentalBiology, SUNYUpstateMedical
University. mccaslaj@mail.upstate.edu
 Dennis J. Stelzner, Ph.D., InterimChair, Departmentof Cell and DevelopmentalBiology, SUNYUpstateMedical
University. stelznerj@upstate.edu