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16 – 03 - 2012
 The Hague
 What is DIY Bio?
 Goals & Motivation
 DIYBio tools and materials
 Challenges and constraints
 Knowledge sharing
 Ethics and safety
Genomics               Health

                   Discovery         Science




Home brewing                                                         SynBio



Ecology        Biology
                                     DIY                 Design
                                     Bio
Microbiology
                                                                Bioremediation



                                                    Open Standards
                                    Education

                     Workshops
                                                Self Teaching
 Build what you can dream of
“If I were 13 again, I would be hacking biology instead of
computers”
                                               - Bill Gates
“most of the action is in DIY biology — manipulating
genetic code the way a previous generation of hackers
manipulated computer code. It’s still in the fun stage”
                                             -Tim O’Reilly
                                 http://www.wired.com/magazine/2010/04/ff_hackers/all/1
 Living code:


AACATGACCTGACGA

 Digital code:


100101001110101010101010100101010
10010101010010101101101111001
 Easy way to put DNA in cells
  DIY Bio friendly organisms
     Model organisms
     Easy to use, techniques are known
     Safe, fun and easy to grow

Moss                     Halobacterium               Acinetobacter




http://www.ncbe.reading.ac.uk/NCBE/SAFETY/bacteria.html
 deCODEme, Navigenics and 23andme
 DIYgenomics app: comparison of suppliers for 20
 conditions (diabetes, cancers, heart disease, etc.)
 Resources
 Equipment
 Access to chemicals
 Proper lab environment
 Biosafety Regulations
   Don’t be stupid
 Patents
   Need for Open Source DNA / Proteins
 Access to knowledge and journals
 GenSpace
   BSL1-certified open lab in NYC


 IndieBiotech
   Class1-certified spare bedroom


 BioCurious
   Community lab in Mountview, CA
“Tuur Van Balen, a Belgian designer, has been making the speaking-circuit rounds,
showing audiences how to inject yogurt bacteria with antidepressant qualities,
making it possible for anyone to have a feel-good breakfast treat.”
   http://diybio.org/codes/
 Desire to create > desire to destroy
 Fear of hobyist or national biowarfare programs?
 Extract DNA from a fruit
 Probe and spool real DNA
 Build a double helix
 Solve a chromosome puzzle
 http://www.instructables.com/id/Project-Paper-clone/
Dutch DIYBio Meetup 1

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Dutch DIYBio Meetup 1

  • 1. 16 – 03 - 2012 The Hague
  • 2.  What is DIY Bio?  Goals & Motivation  DIYBio tools and materials  Challenges and constraints  Knowledge sharing  Ethics and safety
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  • 5. Genomics Health Discovery Science Home brewing SynBio Ecology Biology DIY Design Bio Microbiology Bioremediation Open Standards Education Workshops Self Teaching
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  • 7.  Build what you can dream of
  • 8. “If I were 13 again, I would be hacking biology instead of computers” - Bill Gates “most of the action is in DIY biology — manipulating genetic code the way a previous generation of hackers manipulated computer code. It’s still in the fun stage” -Tim O’Reilly http://www.wired.com/magazine/2010/04/ff_hackers/all/1
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  • 11.  Living code: AACATGACCTGACGA  Digital code: 100101001110101010101010100101010 10010101010010101101101111001
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  • 13.  Easy way to put DNA in cells  DIY Bio friendly organisms  Model organisms  Easy to use, techniques are known  Safe, fun and easy to grow Moss Halobacterium Acinetobacter http://www.ncbe.reading.ac.uk/NCBE/SAFETY/bacteria.html
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  • 15.  deCODEme, Navigenics and 23andme  DIYgenomics app: comparison of suppliers for 20 conditions (diabetes, cancers, heart disease, etc.)
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  • 17.  Resources  Equipment  Access to chemicals  Proper lab environment  Biosafety Regulations  Don’t be stupid  Patents  Need for Open Source DNA / Proteins  Access to knowledge and journals
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  • 21.  GenSpace  BSL1-certified open lab in NYC  IndieBiotech  Class1-certified spare bedroom  BioCurious  Community lab in Mountview, CA
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  • 24. “Tuur Van Balen, a Belgian designer, has been making the speaking-circuit rounds, showing audiences how to inject yogurt bacteria with antidepressant qualities, making it possible for anyone to have a feel-good breakfast treat.”
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  • 26. http://diybio.org/codes/
  • 27.  Desire to create > desire to destroy  Fear of hobyist or national biowarfare programs?
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  • 29.  Extract DNA from a fruit  Probe and spool real DNA  Build a double helix  Solve a chromosome puzzle