This document describes research into a new dual-enzyme CatalyCEST MRI technique that could help detect cancer. The technique uses two enzymes, pig-liver esterase and amino peptidase, which act on a substrate to produce the contrast agent salicylic acid. Mass spectrometry confirmed salicylic acid was produced, but CEST scans did not detect it, likely due to low concentration. Reactions were optimized by increasing enzyme and substrate concentrations, but CEST still did not detect salicylic acid. While the dual-enzyme CatalyCEST technique shows promise for more specific cancer detection, further work is needed to produce high enough contrast agent concentrations for detection by CEST MRI.