The document describes the typical drug discovery process in 6 steps: 1) Discovery and screening of 10,000-20,000 candidate drugs through high-throughput screening and target validation. 2) Lead optimization through combinatorial chemistry and structure-based drug design. 3) Evaluation of absorption, distribution, metabolism, excretion and toxicity (ADMET). 4) Clinical trials in humans. 5) New drug application (NDA) approval by regulatory agencies. 6) Marketing of an approved drug.

1. Drug Discovery Process – Style 7
10,000 – 20,000 candidate drugs
Discovery &
Screening Step 1
High throughput
screening & target
validation Lead Optimization
Step 2 combinatorial
chemistry/ structure-
based drug design
ADMET
Adsorption, distribution, Step 3
metabolism, excretion,
toxicity studies
Step 4 Clinical Trials
Step 5
NDA Approved
1 Drug to
Market
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3. Drug Discovery Process – Style 7
Discovery &
Step 1 Screening
High throughput
screening & target
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validation
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4. Drug Discovery Process – Style 7
Step 1
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Lead Optimization
Step 2 combinatorial
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based drug design
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5. Drug Discovery Process – Style 7
Step 1
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ADMET
Adsorption, • Your Text Goes here
Step 3
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metabolism, excretion, diagram
Step 4 toxicity studies
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6. Drug Discovery Process – Style 7
Step 1
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Step 4 Clinical Trials
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Step 1
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Step 5 NDA Approved
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8. Drug Discovery Process – Style 7
Step 1
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this awesome diagram
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• Your Text Goes here
1 Drug to
Market
Your Logo

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