The document summarizes the typical drug discovery process in 6 steps:
1) Discovery and screening of 10,000-20,000 candidate drugs through high-throughput screening and target validation.
2) Lead optimization through combinatorial chemistry and structure-based drug design.
3) Testing for absorption, distribution, metabolism, excretion, and toxicity (ADMET).
4) Clinical trials in humans.
5) New drug application (NDA) approval by regulatory agencies.
6) Marketing of an average of 1 new drug.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
Securing your Kubernetes cluster_ a step-by-step guide to success !KatiaHIMEUR1
Today, after several years of existence, an extremely active community and an ultra-dynamic ecosystem, Kubernetes has established itself as the de facto standard in container orchestration. Thanks to a wide range of managed services, it has never been so easy to set up a ready-to-use Kubernetes cluster.
However, this ease of use means that the subject of security in Kubernetes is often left for later, or even neglected. This exposes companies to significant risks.
In this talk, I'll show you step-by-step how to secure your Kubernetes cluster for greater peace of mind and reliability.
Software Delivery At the Speed of AI: Inflectra Invests In AI-Powered QualityInflectra
In this insightful webinar, Inflectra explores how artificial intelligence (AI) is transforming software development and testing. Discover how AI-powered tools are revolutionizing every stage of the software development lifecycle (SDLC), from design and prototyping to testing, deployment, and monitoring.
Learn about:
• The Future of Testing: How AI is shifting testing towards verification, analysis, and higher-level skills, while reducing repetitive tasks.
• Test Automation: How AI-powered test case generation, optimization, and self-healing tests are making testing more efficient and effective.
• Visual Testing: Explore the emerging capabilities of AI in visual testing and how it's set to revolutionize UI verification.
• Inflectra's AI Solutions: See demonstrations of Inflectra's cutting-edge AI tools like the ChatGPT plugin and Azure Open AI platform, designed to streamline your testing process.
Whether you're a developer, tester, or QA professional, this webinar will give you valuable insights into how AI is shaping the future of software delivery.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
💥 Speed, accuracy, and scaling – discover the superpowers of GenAI in action with UiPath Document Understanding and Communications Mining™:
See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
Speakers:
👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024Tobias Schneck
As AI technology is pushing into IT I was wondering myself, as an “infrastructure container kubernetes guy”, how get this fancy AI technology get managed from an infrastructure operational view? Is it possible to apply our lovely cloud native principals as well? What benefit’s both technologies could bring to each other?
Let me take this questions and provide you a short journey through existing deployment models and use cases for AI software. On practical examples, we discuss what cloud/on-premise strategy we may need for applying it to our own infrastructure to get it to work from an enterprise perspective. I want to give an overview about infrastructure requirements and technologies, what could be beneficial or limiting your AI use cases in an enterprise environment. An interactive Demo will give you some insides, what approaches I got already working for real.
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024
Drug discovery process style design 7 powerpoint presentation templates.
1. Drug Discovery Process – Style 7
10,000 – 20,000 candidate drugs
Discovery &
Screening Step 1
High throughput
screening & target
validation Lead Optimization
Step 2 combinatorial
chemistry/ structure-
based drug design
ADMET
Adsorption, distribution, Step 3
metabolism, excretion,
toxicity studies
Step 4 Clinical Trials
Step 5
NDA Approved
1 Drug to
Market
www.slideteam.net Your Logo
2. Drug Discovery Process – Style 7
Discovery &
Step 1 Screening
High throughput
screening & target
Your Text Here
validation
Step 2 Your Text Goes here. Download
this awesome diagram
• Your Text Goes here
Step 3
• Download this awesome
diagram
Step 4 • Bring your presentation to life
• Capture your audience’s
attention
Step 5
• All images are 100% editable in
PowerPoint
• Pitch your ideas convincingly
• Your Text Goes here
Step 6
www.slideteam.net Your Logo
3. Drug Discovery Process – Style 7
Step 1
Put Text Here
Lead Optimization
Step 2 combinatorial
Your Text Goes here. Download
chemistry/ structure- this awesome diagram
based drug design
• Your Text Goes here
Step 3
• Download this awesome
diagram
Step 4 • Bring your presentation to life
• Capture your audience’s
attention
Step 5
• All images are 100% editable in
PowerPoint
• Pitch your ideas convincingly
• Your Text Goes here
• All images are 100% editable in
Step 6 PowerPoint
• Pitch your ideas convincingly
www.slideteam.net Your Logo
4. Drug Discovery Process – Style 7
Step 1
Your Text Goes Here
Step 2 Your Text Goes here. Download
this awesome diagram
ADMET
Adsorption, • Your Text Goes here
Step 3
distribution, • Download this awesome
metabolism, excretion, diagram
Step 4 toxicity studies
• Bring your presentation to life
• Capture your audience’s
attention
Step 5
• All images are 100% editable in
PowerPoint
• Pitch your ideas convincingly
• Your Text Goes here
• All images are 100% editable in
Step 6 PowerPoint
• Pitch your ideas convincingly
www.slideteam.net Your Logo
5. Drug Discovery Process – Style 7
Step 1
Put Your Text Here
Step 2 Your Text Goes here. Download
this awesome diagram
• Your Text Goes here
Step 3
• Download this awesome
diagram
Step 4 Clinical Trials
• Bring your presentation to life
• Capture your audience’s
attention
Step 5
• All images are 100% editable in
PowerPoint
• Pitch your ideas convincingly
• Your Text Goes here
• All images are 100% editable in
Step 6 PowerPoint
• Pitch your ideas convincingly
www.slideteam.net Your Logo
6. Drug Discovery Process – Style 7
Step 1
Your Text Here
Step 2 Your Text Goes here. Download
this awesome diagram
• Your Text Goes here
Step 3
• Download this awesome
diagram
Step 4 • Bring your presentation to life
• Capture your audience’s
attention
Step 5 NDA Approved
• All images are 100% editable in
PowerPoint
• Pitch your ideas convincingly
• Your Text Goes here
Step 6
www.slideteam.net Your Logo
7. Drug Discovery Process – Style 7
Step 1
Your Text Goes Here
Step 2 Your Text Goes here. Download
this awesome diagram
• Your Text Goes here
Step 3
• Download this awesome
diagram
Step 4 • Bring your presentation to life
• Capture your audience’s
attention
Step 5
• All images are 100% editable in
PowerPoint
• Pitch your ideas convincingly
• Your Text Goes here
1 Drug to
Market
www.slideteam.net Your Logo
8. All images are 100% editable in PowerPoint
“Change color, size and orientation of any icon to your liking”
www.slideteam.net
9. Ungrouping the object
2
1
3
1. Right click the object.
2. Choose Group and then Ungroup.
3. Click beside the object and drag the arrow over it.
www.slideteam.net
10. Edit Color
2 3
1
1. Select the shape to change the color and Right click the object( click any object which you
want to change color)
2. Choose Format Shape in the dialog box.
3. Choose “Fill” in the Format Shape box then “Solid” or “Gradient” depending on the
appearance of the object. Change colour as shown in the picture.
www.slideteam.net