Drospirenone is a progestin medication used in birth control pills and menopausal hormone therapy. It is available alone and in combination with estrogen. Drospirenone works by inhibiting ovulation and thickening cervical mucus. It also has anti-mineralocorticoid and anti-androgenic effects. Common side effects include menstrual changes, headache, and nausea. Drospirenone can interact with other drugs metabolized by CYP3A4 and may increase potassium levels when taken with other medications like ACE inhibitors. It is used to prevent pregnancy and treat conditions like PMDD and acne.