This document provides biographical and professional information about Dr. Anastasios Manessis, including his education, training, licensure, certifications, appointments, clinical responsibilities, research experience, publications, presentations, and honors. It details his medical career path from obtaining his MD and completing residency in internal medicine and pediatrics, to becoming board certified in endocrinology and holding various teaching and clinical roles in New York.

1. Anastasios Manessis, MD, FACE
275 Seventh Avenue
2nd
Floor
New York, NY 10011
Office: 212-675-9332
Cell: 917-733-3436
E-Mail: a_manessis@yahoo.com
Education: Doctor of Medicine
University at Buffalo School of Medicine
Buffalo, New York
August 1997-May 2001
Bachelor of Science in Biochemistry, Summa Cum Laude
Manhattan College
New York, NY
January 1990-May 1994
Internship: Combined Internal Medicine and Pediatrics
St. Vincent’s Hospital and Medical Center, New York, NY
July 2001-June 2002
Residency: Combined Internal Medicine and Pediatrics
St. Vincent’s Hospital and Medical Center, New York, NY
July 2002-June 2005
Chief Residency: Department of Internal Medicine-Primary Care Tract
St. Vincent’s Hospital and Medical Center, New York, NY
July 2005-June 2006
Fellowship: Fellow in Endocrinology, Diabetes and Metabolism
New York Medical College
St. Vincent’s Hospital and Medical Center, New York, NY
July 2006-June 2008
Licensure: New York State Medical License
2005-Present
Certification: Board Certified in Internal Medicine, 2005
Board Certified in Endocrinology, 2009
Memberships: The Obesity Society – 2008-Present
The Endocrine Society – 2006-Present
American Association of Clinical Endocrinologists – 2006-Present
Hellenic Medical Society of New York – 2003-Present
American College of Physicians – 2001-Present
Honors and Awards: Queens Tribune
Best of Queens
2014
New York Times Magazine
Super Doctors

2. 2013 & 2014
The Heart of Medicine Award
Offered to the Combined Medicine/Pediatric Senior Resident with
a Great Charity of Spirit and Community Service.
June 2005
Phi Beta Kappa Honor Society,
Achievement in the Liberal Arts
May 1994
Sigma Xi Honor Society,
Scientific Research Society
September 1993
Pew Foundation Student - Summer Research Fellowship
Academic grant offered for summer research during college;
Summers of 1992 and 1993
Hospital Appointment: Attending Physician
VA Medical Center
December 2013-Present
Attending Physician
Mount Sinai Hospital Queens
November 2012-Present
Attending Physician
New York Downtown Hospital
November 2011-Present
Attending Physician
New York University Medical Center
New York, NY
April 2010-Present
Assistant Clinical Professor of Medicine
Department of Endocrinology, Diabetes and Metabolism
New York Medical College
St. Vincent’s Hospital and Medical Center, New York, NY
July 2008-April 2010
Academic Appointments: Assistant Clinical Professor of Medicine
New York Hospital-Cornell
June 2013-Present
Clinical Instructor
New York University Medical School
July 2008–Present

3. Clinical Responsibilities: Endocrine Teaching Attending
Inpatient and Outpatient
New York University Medical Centers
May 2010-Present
General Medicine Teaching Attending on Medical Wards
Saint Vincent’s Catholic Medical Centers
July 2008-April 2010
Endocrine Teaching Attending
Inpatient and Outpatient
Saint Vincent’s Catholic Medical Centers
July 2008–April 2010
Director, Medical Weight Loss Management Clinic
Saint Vincent’s Catholic Medical Centers
September 2008-April 2010
Director, Insulin Pump Clinic
Saint Vincent’s Catholic Medical Centers
January 2009-April 2010
Endocrine Consultant,
Inpatient and Outpatient, Faculty Practice
Saint Vincent’s Catholic Medical Centers
July 2008-April 2010
Research: Research Assistant
Aghia Sophia Children’s Hospital, Athens, Greece
Department of Pediatric Endocrinology, Katerina Dacou, M.D.
September 1994 – June 1997
Searched for glucokinase mutations on chromosome 7 associated with
Maturity Onset Diabetes of the Young Type 2 (MODY-2).
Research Assistant
Albert Einstein College of Medicine, New York, NY
Department of Microbiology and Immunology, Marcia Goldberg, M.D.
September 1994 – June 1997
Isolated and characterized factors of Shigella Flexneri involved in the
bacterial invasion of colonic epithelial cells.
Research Assistant
Manhattan College, New York, NY
Department of Biological Sciences, James L. Eliason, Ph.D.
Summers of 1992 and 1993
Studied the repressor of bacteriophage P1 a temperate phage of E.
coli by mutating the gene in order to determine the amino acids
necessary for protein function.
Study Coordinator
St. Vincent’s Hospital and Medical Center, New York, NY
Department of Internal Medicine
Section of Endocrinology
July 2006 - Present

4. Global Hypopituitary Control and Complications Study (HypoCCS):
Evaluating Growth Hormone Replacement Therapy in Growth
Hormone Deficient Adults.
Main Investigator
St. Vincent’s Hospital and Medical Center, New York, NY
Department of Internal Medicine
Section of Endocrinology
January 2009 – April 2010
Creating a database of all patients enrolled in the medical weight loss
management clinic to investigate the effects of therapeutic options and
establish a hospital-based referral for bariatric surgery.
Gotham Cardiovascular
Research, PC c/o NYCVA
Research Support: Principal Investigator: SUSTAIN STUDY: A long-term, randomised,
double-blind, placebo-controlled, multinational, multi-centre trial to
evaluate cardiovascular and other long-term outcomes with
semaglutide in subjects with type 2 diabetes.
Jan 2013 – April 2016
Sub-Investigator: REDUCE-IT STUDY: A Multi-Center, Prospective,
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
to Evaluate the Effect of AMR101 on Cardiovascular Health and
Mortality in Hypertriglyceridemic Patients
with Cardiovascular Disease or at High Risk for Cardiovascular
Disease: REDUCE-IT (Reduction of Cardiovascular Events with EPA –
Intervention Trial)
April 2014 – Present
Principal Investigator: SENIOR STUDY: A randomized, open-label, 2-
arm parallel-group, multicenter, 26-week study assessing the safety
and efficacy of HOE901-U300 versus Lantus in older patients with
type 2 diabetes inadequately controlled on antidiabetic regimens either
including no insulin, or with basal insulin as their only insulin.
Feb 2015 - Present
Principal Investigator: ORAL STUDY: Multiple dose trial examining
dose range, escalation and efficacy of oral semaglutide in subjects
with type 2 diabetes.
October 2013 - 2015
Principal Investigator: REAL WORLD: A randomized, open-label,
parallel group real world pragmatic trial to assess the clinical and
health outcomes of Toujeo® compared to commercially available
basal insulins for initiation of therapy in insulin naïve patients with
uncontrolled type 2 diabetes mellitus.
Jan 2016 – Present

5. Principal Investigator: LPS14587: A randomized, open-label, parallel
group real world pragmatic trial to assess the clinical and health
outcomes of Toujeo® compared to commercially available basal
insulins for initiation of therapy in insulin naïve patients with
uncontrolled type 2 diabetes mellitus.
2016 - Present
Principal Investigator: EFC13794: A 26-week open-label study
assessing lhe efficacy and safety of the insulin glargine/lixisenatide
fixed ratio combination in adults with Type 2 Diabetes inadequately
controlled on GLP-1 receptor agonist and metformin ± pioglitazone
2016 – Present
Educational Projects: A. Manessis, Offering twice a month series of morning and noon
conferences to improve and enhance the education of Internal
Medicine residents regarding management of Endocrine related
disorders.
July 2008-April 2010
A. Manessis, I. Young, P. Bukberg, V. Yen. Facilitating a monthly
basis Endocrine Board Review Session to enhance the education of
the endocrine fellows.
September 2008 – April 2010
Publications: A. Manessis, S. Lascher, P Bukberg, V Yen, S Sadek, I
Young. Quantifying Amount of Adsorption of Levothyroxine
By PEG Tubes.
Journal of Parenteral and Enteral Nutrition. 2007 32 (2): 197-200.
K. Shere, S. Sallustio, A. Manessis, T. Aversa and M. Goldberg,
Disruption of IcsP the Major Shigella Protease that Cleaves IcsA,
accelerates actin-base Motility. Molecular Microbiology, 1998. 25 (6):
451-462
N. Kaviani, A. Manessis, P Bukberg. A case of Severe Osteoporosis
in a Patient with AIDS Secondary to Drug Interaction between RTV
boosted Protease Inhibitors and Inhaled Fluticasone. Accepted for
Publication at Endocrine Practice.
Abstracts: E. Walsh, A. Manessis, I. Young. Thyrotoxic Periodic Paralysis.
American College of Physicians, New York Chapter Poster
Presentation, March 24, 2007, New York, New York.
Presentations – National: A. Manessis, I. Young. Teriperatide Treatment in Hungry Bone
Syndrome. The Second Annual Endocrine Fellows Research
Conference on Metabolic Bone Diseases. Oral Presentation. August
2, 2007, Santa Fe, New Mexico
Presentations – Intramural: A. Manessis, Metabolic Complications of HIV and Antiretrovirals,
Department of Internal Medicine, Section of HIV, Saint Luke’s-
Roosevelt Hospital, June 13, 2009

6. A. Manessis, Metabolic Complications of HIV and Antiretrovirals,
Grand Rounds, Department of Internal Medicine, Section on HIV,
Saint Vincent’s Catholic Medical Centers-Manhattan, June 9, 2009
A. Manessis, Challenges of Oral Hypoglycemic Agents, Grand
Rounds, Department of Community Medicine, Saint Vincent’s Catholic
Medical Centers-Manhattan, June 3, 2008
A. Manessis, Finding New Treatments for Diabetes – How Good?,
Grand Rounds, Department of Community Medicine, Saint Vincent’s
Catholic Medical Centers-Manhattan, May 1, 2007
. A. Manessis, Management of Thyroid Dysfunction During Pregnancy
and Postpartum. Grand Rounds, Department of Obstetrics and
Gynecology, Saint Vincent’s Catholic Medical Centers-Manhattan,
March 20, 2007

7. A. Manessis, Metabolic Complications of HIV and Antiretrovirals,
Grand Rounds, Department of Internal Medicine, Section on HIV,
Saint Vincent’s Catholic Medical Centers-Manhattan, June 9, 2009
A. Manessis, Challenges of Oral Hypoglycemic Agents, Grand
Rounds, Department of Community Medicine, Saint Vincent’s Catholic
Medical Centers-Manhattan, June 3, 2008
A. Manessis, Finding New Treatments for Diabetes – How Good?,
Grand Rounds, Department of Community Medicine, Saint Vincent’s
Catholic Medical Centers-Manhattan, May 1, 2007
. A. Manessis, Management of Thyroid Dysfunction During Pregnancy
and Postpartum. Grand Rounds, Department of Obstetrics and
Gynecology, Saint Vincent’s Catholic Medical Centers-Manhattan,
March 20, 2007