Swine Health Programs Update - Dr. Troy Bigelow, DVM, USDA, APHIS, VS, from the 2015 NIAA Annual Conference titled 'Water and the Future of Animal Agriculture', March 23 - March 26, 2015, Indianapolis, IN, USA.
More presentations at http://www.trufflemedia.com/agmedia/conference/2015_niaa_water_future_animal_ag
1. USDA Swine Program
Initiatives and Updates:
Collaborations to Achieve
Results
Troy T. Bigelow
U.S. Department of Agriculture
Animal and Plant Health Inspection Service
Veterinary Services
March 24, 2015
Veterinary Services
2. Veterinary Services Swine Health Programs
Overview
• Update on CIS activities
• SECD and collaborations
• Business plans
2
3. Swine activities FY 2014 and FY15
• Comprehensive integrated surveillance
activities
– PRV / swine brucellosis surveillance
– Classical swine fever surveillance
– ASF / FMD surveillance pilot
– Influenza A virus in swine surveillance
– Enhanced passive surveillance
– Swine health protection
• SECD
• Trichinae
3
4. CIS Swine Surveillance
• Pseudorabies/ Swine Brucellosis Activities
– Surveillance streams
• Diagnostic Laboratory
• High risk swine
• Slaughter stream
– 99.9 percent of domestic swine samples were negative
• Slaughter samples remain negative
• Occasional finding of positive from high risk herds with high
probability of feral swine contact
– Feral swine remain a risk- Monitoring activities indicated
21 percent of feral swine tested positive for PRV (FY13
convenience samples)
– Pilot swine brucellosis testing in select NAHLN labs this
FY.
4
6. Surveillance
Stream
FY 2013
Specimens
FY 2014
Specimens
Sick Pigs
Specimens
submitted to VDL
2285 2,838
Slaughter Swine
meeting collection
definition
2285 2,198
Swine with high
probability of
exposure
3,991 4,941
Other tested
samples (low risk)
- -
Feral Swine 2,383 2,789
FAD Submission 3 animals 4 animals
6
CIS Swine Surveillance (CSF)
7. Influenza A Virus in Swine
7
CIS Swine Surveillance
430
1,763
2,701
4,994
6,703
1,8081,546
5,460
9,457
21,728
22,550
5,356
0
5,000
10,000
15,000
20,000
25,000
FY 2010 FY 2011 FY 2012 FY 2013 FY 2014 FY 2015 YTD
Accessions Samples
USDA IAV in swine surveillance: Number of accessions and samples tested
FY 2010 through FY 2015 mid feb
8. 8
CIS Swine Surveillance (IAV)
Number of accessions with each IAV-S virus subtype present by month (FY12 through FY15 YTD)
0
10
20
30
40
50
60
70
80
90
H1N1 H1N2 H3N2 H3N1 Mixed
Accessions FY14-15 YTD
H1N1 = 737
H1N2 = 385
H2N3 = 703
H3N1 = 8
Mixed = 83
9. Recent efficiencies in IAV-S program
1. Changes in the testing algorithm implemented June 2014:
• To gain efficiency at obtaining viruses from submitted
samples
• Result: the average % of VI (+) samples has increased from
~31% to ~46%
2. Changes in the repository implemented February 2015
• On receipt of samples, only grow out viruses chosen to go
into full genomic sequencing (“random” sampling”, 16/month)
• And viruses identified as “viruses of interest” by NADC
• Result: May be a 2-4 week delay in getting a virus that is not
already grown out
9
10. IAV-S :
Program analysis & review underway:
APHIS PPD Internal analysis
• Analyze program, achievements, outcomes generated
• Collect cooperator /key stakeholder views on current and desired
future of IAV-S surveillance in the U.S.
• Identify / analyze IAV-S surveillance cost factors & develop
forward projections
Contracted external technical epidemiologic review
• Evaluate the overall surveillance design, sampling efficiency,
sample selection and submission process, sampled populations,
representativeness of data
• Provide recommendations for process improvement and system
efficiencies
10
11. CIS Swine Surveillance
ASF and FMD Surveillance Pilot
• Objectives:
1. Enhance awareness for the reporting /collection of samples from
cases compatible with ASF and FMD.
2. Implement active diagnostic testing for ASF and FMD and
messaging results: surveillance in eight authorized NAHLN
laboratories.
3. Collect baseline surveillance information from surveillance
streams that could be used to substantiate ASF and FMD disease
freedom and to monitor for early detection of disease.
4. Exercise a communication plan for potential suspect cases of
ASF and FMD and ensure that all parties involved understand the
communication process and implement it in an effective and timely
manner.
5. Increase diagnostics preparedness and provide the laboratory
testing network with an exercise for a potential outbreak.
11
12. • 12 month pilot / 8 approved NAHLN labs
• Notification plan = handled same as CSF
• ASF or FMD suspected FAD investigation
• Surveillance streams = CSF and high value PRV
• Test: rRT-PCR
• Sample types
ASF = whole blood (EDTA)
FMD= oral swabs
FADDL validation of additional
tests and tissues
• Runs through August 2015
12
CIS Swine Surveillance
ASF and FMD Surveillance Pilot
13. EPS: Slaughter condemnation
• Monitored weekly
• Three classes of swine
– Sow/boar, Roasters, Market
• Ante-mortem condemnations
– CNS, DOA and Pyrexia
• Postmortem condemnations
– Septicemia, Erysipelas,
Pneumonia
• Signals verified through FSIS
• Verified signals are communicated to industry for
field observations
• Recent info shared on TB findings
13
14. SECD Federal Order (FO)
• June 5, 2014
• Federal Order- Reporting, Herd Monitoring and
Management of Novel Swine Enteric Coronavirus
Disease
– Establishes mandatory disease reporting
– Establishes requirements for development of herd monitoring
and management plans
14
17. SECD and the Federal Order
• Reports issued weekly
• Reporting continues
• Discussions on next steps with
stakeholders
• Program successes include
– premises ID usage
– development of accounting
protocols
– Industry/State engagement
17
18. Swine Health Business Plan
• Developed to outline priorities, objectives,
strategies and field activates
• Tool for guiding spending plans for congressional
appropriations
• Encompasses
– One health
– Comprehensive Surveillance
– Emerging Issues
• Public comment encouraged on an annual basis
• Rolling 5 year plans
18
19. Swine Health Business Plan
• FY 15 Enhanced risk-based CIS
– Performance analysis for CIS Swine surveillance risk
assessments and cost benefit analysis
– Document CIS strategy
– Complete evaluation of FMD/ASF pilot
– Identify regulatory and non regulatory mechanism for
current swine programs
– Pathways assessment
– Develop plans for implementing swine brucellosis in
NAHLN labs
– Continue collaboration on enhanced passive
surveillance
19
20. Swine Health Business Plan
• Emergency preparedness
and response planning
– Database process
improvements and
connectivity
– Collaborations in secure
pork supply
– Collaborations to harmonize
emergency response plans
and data sharing
20
21. Swine Health Business Plan
• Field disease surveillance, investigation
and control activities
– Continue enhancement of field
epidemiological activities
– Develop EMRS for swine epi
– Organize as state/tribal/industry working
groups addressing feral/domestic swine
interface issues
– Collaboration on identifying international
swine health risks
21
22. Swine Health Business Plan
• Zoonotic disease
prevention and response
– Explore alternatives for a
trichinae program with
industry collaborations
– Collaborate with ARS on IAV-
S activities
– Collaborate with public
health stakeholders to
identify and evaluate food
safety information
22
23. Swine Health Business Plan
• Develop swine health studies and special
projects
– Partner with industry to evaluate PIN tag use
for real time surveillance
– Complete ASF, CSF, FMD international
sample collections
– Collaborate with NVSL staff to evaluate FAD
diagnostics
– Continue collaborations on APHIS Feral
Swine Damage Management program
23
24. Swine Health Business Plan
• Enhanced communication
– Outreach to Industry, State partners
– Develop communication plan for swine issues
– Develop a CIS report that can be shared to
stakeholders
– Update swine program resource material
– Develop communication necessary for
revising State status and validation
notification
24
25. Swine Business plan
• Business plans
– Not set in stone; revised each year to update
– Public comment and input encouraged
– Located on the USDA website
– http://www.aphis.usda.gov/wps/portal/aphis/ourfocus/anim
alhealth?urile=wcm%3apath%3a%2Faphis_content_library
%2Fsa_our_focus%2Fsa_animal_health%2Fsa_program_
overview%2Fct_vsbp
– Search for Veterinary Services Business
Plan(s)!
25
Slide 12:
We have seen a steady increase in accessions and samples tested since 2009.
You can see in FY 2013 we essentially doubled our numbers from FY 2012, we maintained/exceeded the 2013 submission level in FY 2014
and FY 15 seems to be on track to continue with an increase in numbers.
The data in FY 15 here reflects only 3 months of FY 14. (Through Dec 31) (submitted Feb 21 2015).
Here is a breakdown of the virus subtypes that are circulating in swine from FY 12 through FY 15 to date (data received Feb 21)
Of the 3,326 Influenza A positive accessions submitted in FY 2014 through Q1 FY 15 the subtypes are:
• 737 H1N1,
• 385 H1N2
• 703 H3N2 , and
8 H3N1 subtypes.
• Eighty-three accessions (about 4.5% of the accessions) contained mixed subtypes –likely due to oral fluid submissions
Note- not all positive accessions will have a virus successfully isolated or be subtyped (various reasons)
~ 60% of (+) accessions in FY 2014 were subtyped..
The changes in the testing algorithm that were instituted in June 2014 are beginning to show value in the data.
Those changes included
1) cutoff CT values for further testing beyond the Matrix PCR for both oral fluids and nasal swabs, and
2) a decrease in the number of Oral fluid samples allowed (5) in the 10 sample maximum per accession.