DNA Guide is developing genomic management software to address issues of privacy, regulation, and ease of use of genetic data. Their solution will (1) use values in DNA samples to uniquely and anonymously identify and store genetic data, (2) enable dynamic regulation and compliance of genetic data down to the base pair level, and (3) make complex genetic information simple through mobile tools and graphic representations. DNA Guide aims to follow genetic data into healthcare, research, consumer, and pharmaceutical marketplaces to become the platform for universal health records.
Wearables iot development for patient engagementLucas Holt
Unmet Wearable Needs & Innovation for Health.
Role of technology, cost, and adherence in developing - mHealth, sensors, and apps to improve patient care, health, and engagement. Establishing Value-Based Collaborations that work.
Presentation I used as a Strategic Account Manager to sell affiliate programs (purchase subsidies) to strategic accounts. RAMP stands for Regional Affiliate Marketing Program.
Wearables iot development for patient engagementLucas Holt
Unmet Wearable Needs & Innovation for Health.
Role of technology, cost, and adherence in developing - mHealth, sensors, and apps to improve patient care, health, and engagement. Establishing Value-Based Collaborations that work.
Presentation I used as a Strategic Account Manager to sell affiliate programs (purchase subsidies) to strategic accounts. RAMP stands for Regional Affiliate Marketing Program.
“Innovation Levers in Precision Medicine”
Colleen Chien
Professor, Santa Clara University Law School
November 5, 2015
White & Case Digital Health: Rethinking Healthcare in a
Digital World Conference
MEMOTEXT - University of Toronto Masters in Health Informatics guest lecture ...MEMOTEXT Corporation
MEMOTEXT-University of Toronto Masters in Health Informatics guest lecture - Amos Adler change management, patient adherence and mobile health / health IT. Speaking to a group of students about change management and how to deploy their mobile health app projects. Resistance to change from stakeholders and mindshare in health behavior.
The Mobility Monitor Assessment System is an integrated computer system that can precisely track, assess and archive movement data. The MMAS is portable, user friendly, needs only a 12' x 12' area for testing and is affordable to health-care providers. It will bridge the gap between highly subjective measurements and costly stationary systems.
Carl Kesselman and I (along with our colleagues Stephan Erberich, Jonathan Silverstein, and Steve Tuecke) participated in an interesting workshop at the Institute of Medicine on July 14, 2009. Along with Patrick Soon-Shiong, we presented our views on how grid technologies can help address the challenges inherent in healthcare data integration.
Reforming Medical Device approval processes especially in software requires careful consideration of shifting risks to patients without adequate protections.
These slides review problems with current electronic medical record (EMR) systems and makes suggestions for future improvements in design and usability. This work was sponsored by the Szollosi Healthcare Innovation Program (www.TheSHIPHome.org).
Bold ideas are drawn from the imagination, artistic inner talent, inspiration, and vision -- which in turn develop into a “concept.”
The creative team are tasked with developing the look, ambiance, image, culinary experience and overall guest/diner experience, as well as the unique personality of the boutique hotel and fine dining establishment respectively. They are the masters of exploiting the five senses, the motions and engaging the customers amid the aura, the music, the scent, the touch, and taste.
“Innovation Levers in Precision Medicine”
Colleen Chien
Professor, Santa Clara University Law School
November 5, 2015
White & Case Digital Health: Rethinking Healthcare in a
Digital World Conference
MEMOTEXT - University of Toronto Masters in Health Informatics guest lecture ...MEMOTEXT Corporation
MEMOTEXT-University of Toronto Masters in Health Informatics guest lecture - Amos Adler change management, patient adherence and mobile health / health IT. Speaking to a group of students about change management and how to deploy their mobile health app projects. Resistance to change from stakeholders and mindshare in health behavior.
The Mobility Monitor Assessment System is an integrated computer system that can precisely track, assess and archive movement data. The MMAS is portable, user friendly, needs only a 12' x 12' area for testing and is affordable to health-care providers. It will bridge the gap between highly subjective measurements and costly stationary systems.
Carl Kesselman and I (along with our colleagues Stephan Erberich, Jonathan Silverstein, and Steve Tuecke) participated in an interesting workshop at the Institute of Medicine on July 14, 2009. Along with Patrick Soon-Shiong, we presented our views on how grid technologies can help address the challenges inherent in healthcare data integration.
Reforming Medical Device approval processes especially in software requires careful consideration of shifting risks to patients without adequate protections.
These slides review problems with current electronic medical record (EMR) systems and makes suggestions for future improvements in design and usability. This work was sponsored by the Szollosi Healthcare Innovation Program (www.TheSHIPHome.org).
Bold ideas are drawn from the imagination, artistic inner talent, inspiration, and vision -- which in turn develop into a “concept.”
The creative team are tasked with developing the look, ambiance, image, culinary experience and overall guest/diner experience, as well as the unique personality of the boutique hotel and fine dining establishment respectively. They are the masters of exploiting the five senses, the motions and engaging the customers amid the aura, the music, the scent, the touch, and taste.
These slides use concepts from my (Jeff Funk) course entitled Biz Models for Hi-Tech Products to analyze the business model for 23andMe’s personal genomics service. 23andMe provides personal health care analysis and ancestry information to individuals that are based on a partial analysis of an individual’s DNA data. Driven by the falling cost of DNA sequencing, 23 and Me provides this information for $99 and a small amount of saliva. While this business model may succeed particularly if the FDA eventually approves the health care portion of the service, we recommend that 23andMe develop a new business model. It should offer the service for free to individuals, particularly those who frequent gyms and nutrition stores and sell information about potential athletes to sports teams.
It's an assignment in High technology Entrepreneurship course. I have to pick some new venture and think about its business model , SWOT analysis and 6-force model.
that goes to this presentation.
Possible Solution for Managing the Worlds Personal Genetic Data - DNA Guide, ...DNA Compass
World DNA Day and Genome Day, Dalian China 2011
"Possible Solution for Managing the Worlds Genetic Data" given by Alice Rathjen, Founder & President DNA Guide, Inc.
Proposes genetic tests be given a rating for quality of science, medical utility and viewing risk so as to facilitate the flow of genetic information in a responsible manner from the lab to the physician and patient. Explains how technology combined with public policy could enable both privacy and personalized medicine to thrive. Advocates individual ownership over personal genetic data and suggests the genome as a data format could provide the foundation for digital human rights.
tags: DNA, genetic testing, privacy, personalized medicine, FDA regulation
CORD Rare Drug Conference, June 8 - 9, 2022
Opportunities and Challenges for Data Management Real-World Data and Real-World Evidence
• Patient support programs: Sandra Anderson, Innomar Strategies
• AI for Data Management and Enhancement: Aaron Leibtag, Pentavere
• Patient Support and RWE: Laurie Lambert, CADTH
As the author of “Big Data in Healthcare Hype and Hope,” Dr. Feldman has interviewed over 180 emerging tech and healthcare companies, always asking, “How can your new approach help patients?” Her research shows that data, as an enabling tool, has the power to give us critical new insights into not only what causes disease, but what comprises normal. Despite this promise, few patients have reaped the benefits of personalized medicine. A panel of leading big data innovators will discuss the evolving health data ecosystem and how big data is being leveraged for research, discovery, clinical trials, genomics, and cancer care. Case studies and real-life examples of what’s working, what’s not working, and how we can help speed up progress to get patients the right care at the right time will be explored and debated.
• Bonnie Feldman, DDS, MBA - Chief Growth Officer, @DrBonnie360
• Colin Hill - CEO, GNS Healthcare
• Jonathan Hirsch - Founder & President, Syapse
• Andrew Kasarskis, PhD - Co-Director, Icahn Institute for Genomics & Multiscale Biology; Associate Professor, Genetics & Genomic Studies, Icaahn School of Medicine at Mt. Sinai
• William King - CEO, Zephyr Health
New York eHealth Collaborative Digital Health Conference
November 18, 2014
DNA Guide - Tri Molecular Conference, San FranciscoDNA Compass
Talk covers evolution of digital human beings. How we can expect the genome to follow the same pattern as other user generated content platforms once individuals are allowed to upload their data and control how it is shared. Concept of self-organizing genomes, EHR with real time consent, digital human rights.
The Pistoia Alliance is examining the challenges of the Faster Safe Companion Diagnostics (CDx) by Aligning Discovery & Clinical Data in the Regulatory Domain.
The slides discuss whether the data standards used in the research environment be aligned better with the data standards used in the regulated environment? If so, the time and cost of the development of NGS-based CDx could be reduced.
Suggested solution for navigating genetic data regulation, privacy and ease of use. DNA Guide, Inc.
Mobile platform for visual map of personal genetic data.
A look at the key trends and challenges in applying Big Data to transform healthcare by supporting research, self care, providers and building ecosystems. Purchase the report here: https://gumroad.com/l/PlXP
Big data, RWE and AI in Clinical Trials made simpleHadas Jacoby
Technology is slowly but surely penetrating the healthcare industry in general and the clinical trials sector in particular. New and advanced solutions offer a variety of possibilities aimed to both improving existing processes and creating new and more efficient ones. And on top of all stands the desire to make clinical trials more patient centric.
In all of this, even though some of the technologies have yet to mature enough to meet the high quality standards necessary, it is important to know them and begin imagining the promise they hold for clinical trials.
Precision Medicine & Biomarkers Leaders Summit - Boston USA - 7th & 8th MayTony Couch
This expanding series attracts the leading authorities worldwide working in companion diagnostics, biomarkers, immuno-oncology, liquid biopsies, AI and other facets of precision medicine. It has been praised for its stimulating, interactive and engaging environment where it brings together a multi-disciplined community of researchers, leaders and innovators whose aim is to develop groundbreaking and impactful treatments for patients.
Combining Patient Records, Genomic Data and Environmental Data to Enable Tran...Perficient, Inc.
The average academic research organization (ARO) and hospital has many systems that house patient-related information, such as patient records and genomic data. Combining data from a variety of sources in an ongoing manner can enable complex and meaningful querying, reporting and analysis for the purposes of improving patient safety and care, boosting operational efficiency, and supporting personalized medicine initiatives.
In this webinar, Perficient’s Mike Grossman, a director of clinical data warehousing and analytics, and Martin Sizemore, a healthcare strategist, discussed:
-How AROs and hospitals can benefit from a systematic approach to combining data from diverse systems and utilizing a suite of data extraction, reporting, and analytical tools, in order to support a wide variety of needs and requests
-Examples of proposed solutions to real-life challenges AROs and hospitals often encounter
Supporting a Collaborative R&D Organization with a Dynamic Big Data SolutionSaama
Nikhil Gopinath presents regarding big data solutions at the Big Data and Analytics for Healthcare and Life Sciences Summit on October 18, 2017 in San Francisco, CA.
Snam 2023-27 Industrial Plan - Financial Presentation
DNA Guide - Full Genome Molecular Diagnostics Platform
1. Navigating Genetic Data
Privacy, Regulation and Ease of Use
Presentation @ Beyond the Genome, San Francisco, CA June 2011
DNA Guide, Inc. All rights reserved 2011
Alice Rathjen, President, Founder
alice@dnaguide.com
2. The Problem..
No Path to Market
Genetic Data Explosion
Huge investment in
Sequencing Technologies
and Molecular Diagnostics
Personalized Medicine
R&D
Pharma /
Clinical
Trials
Consumers/
Patients
INSURANCE
Regulation, Privacy, Ease of Use
Health
Services
3. Privacy
Biometric based security allow
written consent to evolve into
“real time” consent
• Use values in DNA sample to uniquely identify
each dataset
• Store and retrieve genetic data anonymously
• Perform audits, merge data
• Re-associate information throughout a
person’s lifetime
• Have variations for different uses
Raw DNA Values
DNA Security Token
11. Removing the Genetic
Education Barrier
Simple Graphic’s to explain genetic variation
Color code for Drug Response Information
Stop!
(check details)
Warning
(check details)
Go
(normal dose)
12. • Traditional model of laboratory services, proprietary algorithms,
legacy single chromosome browsers, no dynamic mechanism for
patient engagement.
• DNA Guide Advantages
– Patient engagement/empowerment focused mobile tools
– Leverage static nature of raw genome data vs public domain,
changing patent landscape, with ability to open up platform to
third party molecular diagnostics
– Provides foundation for universal health record
Competition
13. DNA Guide Product Modules
DNA Security
Token
DNA Compass DNA Body
Use values within the DNA
sample to uniquely identify
every dataset. Token serves
as a dynamic or static IP
address - allowing every
person to become a node on
the network.
DNA Guide provides mobile dynamic
maps of entire genomes and can
perform spatial analysis across
multiple layers of different types of
genetic data.
DNA Guide’s DNA Body will
provide expression data,
medical records, and images to
be linked to a map of the human
body and to genomic location.
14. Human Body Linked to Gene Expression
Electronic Health
Record
Grand SLAM
Long term plans -
expression data and
medical records
linked to a map of
persons body with
electronic health
record user account
derived from their
DNA.
Note: Image of body is
from Google body
browser but reflects DNA
Plans to incorporate map
of body as part of EMR
solution.
15. Go to Market Strategy
Follow the Data into the Marketplace
Large Scale
Enterprise Software
Deployments
Cloud Services
Research
Consumers/
Patients
Payors,
Welness
$120 average per user per year plus transaction fees
Health
Services,
Government
Entities
Pharma,
Clinical Trials,
Molecular
Diagnosticss
16. HEALTH SERVICE
PROVIDER
Assess Patient
Interact with payer to
determine eligibility
Prescribe test
Collect patient DNA sample
Submit DNA sample to lab
View lab information and
interpret results
Provide analysis and
recommendation to patient
Prescribe course of action.
Interface with pharma
regarding personalized
medicine
Interact with pharma with
clinical trial information
$120 avg per user/year subscription
PATIENT
Seeks Health Services
Submits DNA Sample
Views interpretation of results
from physician
Interact with payer regarding
reimbursement
Participation in Clinical Trials
Receives Drugs and Info from
Pharma
INSURANCE and PAYER ENTITIES
Require DNA tests for reimbursement of Rx and determine which genetic tests qualify for reimbursement
LAB
Process sample and results
Provide raw DNA data to
database storage for
interpretation
PHARMA/BIOTECH/R&D
INDUSTRY
Provide sample collection kits
and information regarding
personalized medicine
Interface with physician and
patients in clinical trials
Provide lab with new products
and services
Provide patient with retail info
DNA Guide
Genome Management Software
Information Flow
18. Alice Rathjen
President, Founder
William Kimmerly, Ph.D.
Chief Scientific Officer
Product Dev. Team
Xavier Thomas
Saw Yu Wai
Chris Kritzer
Jeff Protentis (Sales)
ADVISOR
Mark S. Boguski, M.D., Ph.D.
Center for Biomedical Informatics
Harvard Medical School
Team
AWARD
19. Milestones
Milestones Completed
Human Genome Map deployed and tested on all major mobile platforms (iPAD, iPhone, Android, Blackberry)
Pilot Customer Project (Oregon Health & Science University, Harvard Medical School & CBMI)
Secured Mark Boguski, MD, Ph.D., Harvard as advisor.
Discussion on Strategic partnerships underway with industry leaders
Winner Kaufman Women in Science & Engineering Business Idea Competition 2011
World DNA Day Personalized Medicine Panel – Dalian, China 2011
Selected as “technology breakthrough” for Consumer Genetics Conference,
Harvard Personalized Medicine Lab Symposium, Personalized Medicine World Conference
Selected for Health 2.0 San Francisco “Launch”
Seed investment
Finalize agreements with initial customers
Formalize Strategic partnerships
Apply for government grants
Build out additional features
Secure Series A Funding
Series A
Top-tier management team recruited
Secure Major Enterprise Software
20. • Industry transforming technology
• Multiple revenue streams &
capital efficient
• Visionary, dedicated team
DNA Guide
Navigating Genetic Data Regulation, Privacy and Ease of Use
T
G
C
A
Contact: Alice Rathjen
alice@DNAguide.com