The document is a field notebook entry from a ninth semester biochemistry and pharmacy student at the Technical University of Machala. The entry documents an observation on quality standards, normalization, and normalization fields. Specifically, it evaluates quality based on standards. The content discusses HPLC spectra of capsaicinoids and references four sources relating to quantifying capsaicin and dihydrocapsaicin, including studies on their antioxidant activity, inheritance patterns, quantification in rat plasma, and quantification in rabbit plasma and tissues.

1. UNIVERSIDAD TÉCNICA DE MACHALA
FACULTAD DE CIENCIAS QUÍMICAS Y DE LA SALUD
CARRERA DE BIOQUÍMICA Y FARMACIA
ANÁLISIS DE MEDICAMENTOS
DIARIO DE CAMPO N°21
ESTUDIANTE: Javier Eduardo Ramón Caraguay
DOCENTE: Dr. Carlos Alberto García González
FECHA: 04 de Febrero del 2020
CURSO: Noveno Semestre “A”
TEMA: Patrones de calidad, normalización, campos de normalización.
CONTENIDO: Evaluación de calidad a base de patrones.

2. ESPECTROS DE CAPSAICINOIDES
Fuente: Quantitative HPLC Determination of the Antioxidant Activity of Capsaicin on
the Formation of Lipid Hydroperoxides of Linoleic Acid: A Comparative Study against
BHT and Melatonin
Fuente: Inheritance of Capsaicin and Dihydrocapsaicin, Determined by HPLC-ESI/MS,
in an Intraspecific Cross of Capsicum annuum L.

3. Fuente: Simultaneous quantification of capsaicin and dihydrocapsaicin in rat plasma using
HPLC coupled with tandem mass spectrometry
Fuente: A sensitive LC‐MS/MS method for quantifying capsaicin and dihydrocapsaicin in rabbit
plasma and tissue: application to a pharmacokinetic study
FIRMA DEL ESTUDIANTE