4. INTRODUCTION
The APOBEC may be
exposed to many
environmental factors,
for this reason the
researchers believe there
is a specific
environmental factor
causing the mutation of
the APOBEC.
The full genome
sequencing for the
persons with autism will
help also a tratment that
will improved the
medical attention for
these patients.

5. Proteins involved in
immunity produce
cancer-causing
DNA mutations,
study finds
NIH/National institute of
environmental health
sciences.
Published on July 15, 2013

6. The APOBEC are a protein family
responsibles of immunological activities,
these inactivate the viruses and inhibit
mutations of ancient viruses present in the
human genome.
According to studies
these proteins are
influenced by
enveromental factors.

7. Studies made by researchers at the
National Institutes of Health shows APOBEC
mutations even with a greater number that
other mutations in cancer of cervical,
bladder, breast, head and neck and lung
tumors.

8. The researchers examined 2680 shows with
approximately one million of mutations,
whose results were the 70% APOBEC
mutations.

9. Personal opinion
I think that this news is very
important because shows a
significant discovery that could
change the cancer treatment and it
could help to find a cure for this
disease that causes millions of
deaths around the world.

10. First full genome
sequencing for
autism: promise for
future diagnosis,
prevention and
treatment
The american journal of
human genetics.
Published on July 11, 2013

11. The autism is a generalized disorder
spectrum of the development, it causes
delay and especific alterations of the
social development, cognitives and of the
comunication with the environment.
This study was conducted by
the Autism Speaks that is
leader in the science of
autism in the world

12. It was a study done to 99 persons, 32 with
autism spectrum disorder (ASD) and their
two parents, and 3 members of a control
family without ASD, of them were the full
genome sequencing for the autism and
the genetic variations for this disorder.

13. Was also found in this study risk genes
associated to ASD and to epilepsy, social-
cognitive deficit and related syndromes
that are responsibles of ASD.

14. Personal opinion
I think that this news is also very
important because the
discovery of the full genome
sequencing for autism could
allow the creation of new
treatments to improve the
quality of life of persons with
autism and the people around.
Also could allow reverse this
disorder by early diagnosis.

15. Study finds proteins
involved in immunity
produce cancer-
causing DNA
mutations.
These studies could help to
improve the health to
persons with cancer and
autism.

16. The first news tell us
about the mutations of
the APOBEC protein in
many tumors such as
bladder, cervical,
breast, head and neck,
and lung; these could
improved with that
finding.

17. First full genome
sequencing for
autism: promise
for future
diagnosis,
prevention and
treatment

18. "In the future, results
from whole genome
sequencing could
highlight potential
molecular targets for
pharmacological
intervention, and pave
the way for
individualized therapy in
autism. It will also allow
for earlier diagnosis of
some forms of autism,
particularly among
siblings of children with
autism where
recurrence is
approximately 18 per
cent."

19.  News medical. “Proteins involved in immunity
produce cancer-causing DNA mutations study finds”.
Published on July 15, 2013. NIH/National institute of
environmental health sciences.[http://www.news-
medical.net/news/20130715/Proteins-involved-in-
immunity-produce-cancer-causing-DNA-mutations-
study-finds.aspx]
 Science Daily. “ first full genome sequencing for
autism: promise for the future diagnosis, prevention
and treatment”. Published on July 11, 2013. The
American Journal of Human Genetics.
[http://www.sciencedaily.com/releases/2013/07/130
711135319.htm]