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Opportunities to enhance prescribing
efficiency for patients with diabetes in Abu
     Dhabi without compromising care
         Dr Mohammed Abuelkhair
 Head, Pharma/Medicine & Medical Product
               Regulation
G A S N O JC IE
 O L A D BE TV S



  T eg a o teP am c v iln ea dR t n l e ic eU e
    h o l fh h r a o ig a c n aio a M d in s
   po rmo a H A is oid nif a dpo oeo t a du
    rga f t A D t e ty n rm t pim l rg
   pecib ga du e
    rsr in n s.

  Srtg stosa dsric s r po id dt e c ua ete
    t e ie, o l n ev e ae rv e o n o rg h
     a          ,
   u eo e id n eb sdc ic l n c s efciv n s
    s f v e c - ae l a a d o t f t e es
                        in       - e
   inom t nind c io m k ga o gh at c r po id r,
     fr aio       e is n a in m n e l ae rv es
                                     h
   c n u es n p lym k r.
    o s m r a d oic a es

  T ea o tea d w s oa ayec r n t am n
    h im fh u it a t n l   z ur tr t e t
                                e   e
   a po c e a o gp t ns it T p 2d b tsT D )a d
    p ra h s m n aie t w h y e ia ee ( 2 M n
   c m aew hinen t n ltn ad . S c n l ass te
   o p r it traio a s d rs e o dy ses h
                        a             ,
   e tn o d frn m n g m n a po c e/rsr in
    xe t f if e t a a e e t p ra h s ecib g
             e                      p
   p t r a o gd frn fcit s
    at n m n if e ta ilie.
      e          e
MT O S
 EH D



 A d o 5 1rn o p t ns co s fcit s rain
   u it f 6 a d m aie t a rs 3 a ilie t t g
                                       e
  T D p t ns v r y a.
   2 M aie t o e 1 e r

  1s e iais d b ts e tr
    p c lt ia ee c ne,
  1g v rm n ( K C d b ts e tr
    o en e tS M ) ia ee c ne
  1in e e d n piv t sco h s it
     d p n e t r ae e tr o p a

 D t in ld de tn o p t n m n oin ( P l id ,
   aa c e xe t f aie t o itr g B , ip s
         u
  H A c w ig trn lu cio , ec , oa g c m du s
   b 1 , e h, e a fn t n t.) rl l e ic rg
                                    y
  pecib d w eh rh s pecib da m x a d ss
   rsr e , h te tee rsr e t a im l o e
  ( IEg id n e b fr in uin , w eh r s l t am n
  N C u a c ) eoe s l s h te in uin r t e t
                                         e
  d ly da din uintp .
   ea e n s l y e
 
M JRFN IG
 AO IDN S


Pecib g
 rsr in
 H hu eo p tn poe tddu s c d g
   ig s f ae t rtce rg in l in : u
   E p n iv m d ie rlaem d in se . m t r in
     x e s e o if d ee s e ic e ( .g ef m
                                        o
    M / llz eM )v ru g n r s n adrlae
     R gic id R es s e eic t d r ee s
            a                    a
    pe aaio s
     rp rt n
   Gipin in ld gsa l t 5 m T IED I d s
     l t s c in itgipin 0 g WC AL oe
              u                       Y
   E p n iv in uin s c a in uingag e
     x e s e s l s u h s s l lrin
 H hu eo gim p id
   ig s f l e ir e



Q ait o c r
 u ly f ae
 H A ce od din8 % t1 0 )o al aie t w h
   b 1 rc re ( 3 o 0 % f lp t ns it
  d b ts
   ia ee
 L s ta 5 % o p t ns a arc re H A c f
   es h n 0 f aie t h d e od d b 1 o <
M JRFN IG
   AO IDN S


No of patients at each participating
facility




                                       Types of medical intervention used to control diabetes
M JRFN IG
  AO IDN S


HbA1c




             Types of medical intervention used to control diabetes
M JRFN IG
   AO IDN S

Prescribing of agents to control   Trends in prescribing of oral anti-
hyperglycemia                      hyperglycemics.
                                                             Independent    Government    Specialist 
                                                             hospital       Hospital      Center
                                                             (Private)
                                                                                           
                                   Metformin                 39 %           85.5 %         87.6 %
                                                                                           
                                                                                           
                                   Sulphonylurea             47 %           57.4 %         50.5 %
                                                              
                                                                                           
                                   Glitazone                 13 %           20.3 %        12.4 %
                                                              
                                                                                           
                                   Prandial regulators       0 %            3.1 %         5.7 %

                                                                                           
                                   Gliptins                  33%            64.5 %        61 %
                                                                                           
                                   Newer Agents      (eg:                                  
                                   Exanetide)                0 %            7.4 %         3.8 %
                                    
                                                                                           
                                   Older anti                2%             0.8 %         1.0 %
                                   -hyperglycemic agents 
                                   (eg:Acarbose)
M JRFN IG
  AO IDN S


Trends in prescribing of generics   Trends in prescribing sitagliptin
M JRFN IG
  AO IDN S


Trends in prescribing Insulins
M JRFN IG
  AO IDN S


Trends in prescribing sulphonylureas




                                       Gliclazide modified release preparations may
                                       be useful in patients who suffer with
                                       hypoglycaemia with standard release
                                       preparations. However the cost of the
                                       modified release tablets is significantly higher
                                       than standard tablets. In addition Glimepiride
                                       is significantly more expensive than Gliclazide


                                       There is no strong evidence to suggest
                                       increased efficacy or lower incidence of side
                                       effects from Glimepiride use.
M JRFN IG A D C N L S N
 AO IDN S N O C U I SO


 W et aec s c udb rd c db
   e sim t o t o l e e u e y
             s
  a po im tl 3 % tru hfl w ginen t n l
   p rx aey 0 ho g ol in traio a
                         o
  g id l e a drd c guilaio o e p n iv
   u ein s n e u in tist n f x e s e
  m d ie rlaepe aaio s
   o if d ee s rp rt n

 C r c udas im rv db rg lr o itr go
   ae o l l  o po e y e ua m n oin f
  H A c e es
   b 1 lv l

 It d cio o P am c B n f M n g m n
  nr u t n f h r a y e eit a a e e t
     o
  Ss m s o l as h l im rv a po r t s p
   yt s h ud l ep po e p rpiae t
     e         o                       e
  w ec r a drd c c s . I a d io , in rae
   is ae n e u e o t n d it n ce s
                     s
  IN pecib g h l m n o c m l n e a w l
  N rsr in , ep o itr o pia c , s el
  a m n o d ss f rg pecib d e . s t s
   s o itr o e o du s rsr e , .g t ina

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Diabetes presentation dr mohammed abuelkhair logo

  • 1. Opportunities to enhance prescribing efficiency for patients with diabetes in Abu Dhabi without compromising care Dr Mohammed Abuelkhair Head, Pharma/Medicine & Medical Product Regulation
  • 2. G A S N O JC IE O L A D BE TV S  T eg a o teP am c v iln ea dR t n l e ic eU e h o l fh h r a o ig a c n aio a M d in s po rmo a H A is oid nif a dpo oeo t a du rga f t A D t e ty n rm t pim l rg pecib ga du e rsr in n s.  Srtg stosa dsric s r po id dt e c ua ete t e ie, o l n ev e ae rv e o n o rg h a , u eo e id n eb sdc ic l n c s efciv n s s f v e c - ae l a a d o t f t e es in - e inom t nind c io m k ga o gh at c r po id r, fr aio e is n a in m n e l ae rv es h c n u es n p lym k r. o s m r a d oic a es  T ea o tea d w s oa ayec r n t am n h im fh u it a t n l z ur tr t e t e e a po c e a o gp t ns it T p 2d b tsT D )a d p ra h s m n aie t w h y e ia ee ( 2 M n c m aew hinen t n ltn ad . S c n l ass te o p r it traio a s d rs e o dy ses h a , e tn o d frn m n g m n a po c e/rsr in xe t f if e t a a e e t p ra h s ecib g e p p t r a o gd frn fcit s at n m n if e ta ilie. e e
  • 3. MT O S EH D  A d o 5 1rn o p t ns co s fcit s rain u it f 6 a d m aie t a rs 3 a ilie t t g e T D p t ns v r y a. 2 M aie t o e 1 e r 1s e iais d b ts e tr p c lt ia ee c ne, 1g v rm n ( K C d b ts e tr o en e tS M ) ia ee c ne 1in e e d n piv t sco h s it d p n e t r ae e tr o p a  D t in ld de tn o p t n m n oin ( P l id , aa c e xe t f aie t o itr g B , ip s u H A c w ig trn lu cio , ec , oa g c m du s b 1 , e h, e a fn t n t.) rl l e ic rg y pecib d w eh rh s pecib da m x a d ss rsr e , h te tee rsr e t a im l o e ( IEg id n e b fr in uin , w eh r s l t am n N C u a c ) eoe s l s h te in uin r t e t e d ly da din uintp . ea e n s l y e  
  • 4. M JRFN IG AO IDN S Pecib g rsr in  H hu eo p tn poe tddu s c d g ig s f ae t rtce rg in l in : u  E p n iv m d ie rlaem d in se . m t r in x e s e o if d ee s e ic e ( .g ef m o M / llz eM )v ru g n r s n adrlae R gic id R es s e eic t d r ee s a a pe aaio s rp rt n  Gipin in ld gsa l t 5 m T IED I d s l t s c in itgipin 0 g WC AL oe u Y  E p n iv in uin s c a in uingag e x e s e s l s u h s s l lrin  H hu eo gim p id ig s f l e ir e Q ait o c r u ly f ae  H A ce od din8 % t1 0 )o al aie t w h b 1 rc re ( 3 o 0 % f lp t ns it d b ts ia ee  L s ta 5 % o p t ns a arc re H A c f es h n 0 f aie t h d e od d b 1 o <
  • 5. M JRFN IG AO IDN S No of patients at each participating facility Types of medical intervention used to control diabetes
  • 6. M JRFN IG AO IDN S HbA1c Types of medical intervention used to control diabetes
  • 7. M JRFN IG AO IDN S Prescribing of agents to control Trends in prescribing of oral anti- hyperglycemia hyperglycemics.   Independent  Government  Specialist    hospital  Hospital Center (Private)         Metformin  39 % 85.5 %  87.6 %               Sulphonylurea 47 % 57.4 %  50.5 %           Glitazone 13 % 20.3 % 12.4 %             Prandial regulators 0 % 3.1 % 5.7 %         Gliptins 33% 64.5 % 61 %   Newer Agents      (eg:        Exanetide) 0 % 7.4 % 3.8 %           Older anti  2% 0.8 % 1.0 % -hyperglycemic agents  (eg:Acarbose)
  • 8. M JRFN IG AO IDN S Trends in prescribing of generics Trends in prescribing sitagliptin
  • 9. M JRFN IG AO IDN S Trends in prescribing Insulins
  • 10. M JRFN IG AO IDN S Trends in prescribing sulphonylureas Gliclazide modified release preparations may be useful in patients who suffer with hypoglycaemia with standard release preparations. However the cost of the modified release tablets is significantly higher than standard tablets. In addition Glimepiride is significantly more expensive than Gliclazide There is no strong evidence to suggest increased efficacy or lower incidence of side effects from Glimepiride use.
  • 11. M JRFN IG A D C N L S N AO IDN S N O C U I SO  W et aec s c udb rd c db e sim t o t o l e e u e y s a po im tl 3 % tru hfl w ginen t n l p rx aey 0 ho g ol in traio a o g id l e a drd c guilaio o e p n iv u ein s n e u in tist n f x e s e m d ie rlaepe aaio s o if d ee s rp rt n  C r c udas im rv db rg lr o itr go ae o l l o po e y e ua m n oin f H A c e es b 1 lv l  It d cio o P am c B n f M n g m n nr u t n f h r a y e eit a a e e t o Ss m s o l as h l im rv a po r t s p yt s h ud l ep po e p rpiae t e o e w ec r a drd c c s . I a d io , in rae is ae n e u e o t n d it n ce s s IN pecib g h l m n o c m l n e a w l N rsr in , ep o itr o pia c , s el a m n o d ss f rg pecib d e . s t s s o itr o e o du s rsr e , .g t ina