Tobacco originated in North and South America and was used by indigenous peoples for medicinal, religious, and cultural purposes. It was introduced to Europe in the 15th century and grew rapidly in popularity. By the late 19th century, automated cigarette machines were mass producing cigarettes. Cigarettes contain over 4000 chemicals, including 60 carcinogens. Smoking causes numerous health consequences like cancer, heart disease, stroke, and premature death. Quitting smoking at any age can significantly reduce health risks.