The Indian stock market closed lower, with the Sensex down 0.65% and the Nifty down 0.62%. In Europe, major indexes like the CAC, DAX, and FTSE closed slightly lower. In the US, the NASDAQ fell 0.28% while the Dow Jones was nearly flat. On the Nifty, Tata Motors and Glenmark Pharma were the top gainers while United Spirits and Unitech suffered the largest losses. Most sectoral indices ended in the red, with losses led by the defense and midcap indices.