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Lumbar Spinal Stenosis

Conservative Management for the
  “Simple” Minded Practitioner
      By Joe Hlavin PA-C
The Only Way To
Heal Is With Ice Cold
        Steal
Conservative Management
 of LSS is Anything and
Everything Other than the
       Last Slide
 And when the patient in your office tells
                    you:
  I don’t want surgery, you might look
                like this…
But Seriously……..
Current Treatment of Lumbar
          Stenosis

 Role of Non-Operative Management
                 By
          Joseph Hlavin PA-C
Goals of this Presentation
      (BUT Not to bore you)
• Quickly
  – Review the clinical presentation of LSS
  – Review causes of LSS
• List the different conservative treatments
  available
• Propose a debate on when it is reasonable to
  offer conservative management over surgery
• Offer articles/studies as a guide for who, when
  and for how long
Overview
1. Hypertrophy of the Yellow
   Ligament
2. Flattening/bulging disc
3. Facet Hypertrophy
4. Foraminal Stenosis
5. Canal Stenosis
Hallmark Symptoms
•   Neurogenic Claudication
•   +/- Lower back pain
•   +/- hip and/or radicular pain
•   Improvement of pain with forward flexion
    of the lumbar spine:
    – Shopping cart sign
    – Easier walking up hill
Neurogenic Claudication
• Not to be confused with Vascular
  Claudication

  – Neurogenic:
    •   Symptoms w/ walking AND standing
    •   Variable walking distance w/o symptoms
    •   Relief w/ sitting & flexion
    •   Lower extremity pulses OK
Neurogenic Claudication

– Vascular Claudication
   • Symptoms w/ walking BUT NOT standing
   • NO variability in walking distance prior to
     onset of symptoms
   • NO relief with lumbar flexion
   • Diminished pulses in feet
Degenerative Lumbar Stenosis
• Age related: (Spondylosis)
  – Spondylosis – Degeneration
    of the facet joints
  – Degenerative spondylolithesis
  – Facet arthropathy
  – Degenerative disc bulge/spur
  – Hypertrophic ligamentum flavum
Stenosis to a Degree
• Mild
• Moderate
• Severe
Degenerative Lumbar Stenosis
            Mild
Lumbar Stenosis - Moderate
Lumbar Stenosis - Severe
                                                              Flaniken, Doris    H St. Joseph Regional Health Center
                                                                                    St.
                                                              M000473610          LUMBAR SPINE MRI W/O CONTRAST
Flaniken, Doris           A St. Joseph Regional Health Center 12/14/1935
                                       Regional                                                      t2_tse_rst_sag
M000473610                 LUMBAR SPINE MRI W/O CONTRAST F                                      2/12/2007 15:27:21
                                                                                                         001087049
12/14/1935                               t2_tse_rst_tra_msma
F                                         2/12/2007 15:40:26                                             LOC: -6.87
                                                   001087049                                          THK: 4 SP: 4.4
                                                                                                                HFS
                                                 LOC: -100.81
                                                THK: 4 SP: 4.4
                                                          HFS




R                                                            L A                                                  P




EC:   0
SE
FA:   180          L4-5                              Z: 1.60
TR:   8830                                            C: 314
TE:   86                                             W: 708      EC:   0
                                             Compressed 7 :1     SE
                                                                 FA:   170                                  Z: 1.14
Page: 32 of 39            P                     IM: 32 SE: 4     TR:   3750                                  C: 110
                                           cm                          3750
                                                                 TE:   115                                  W: 378
                                                                                                    Compressed 7 :1
                                                                 Page: 9 of 15   F                      IM: 9 SE: 2
                                                                                                 cm
Lumbar Stenosis – Other
               Causes
• Causes of non-
  arthritic lumbar canal
  stenosis:
   –   Disc rupture
   –   Tumor
   –   Abscess
   –   Hematoma
   –   Trauma/FX
Spinal Stenosis - Trauma
Lumbar Stenosis – Abscess
Lumbar Stenosis - Tumors
The Conservative Approach
• Medications
  – NSAIDs
    Acetaminophen
    Oral corticosteroids
    Muscle relaxants
    Narcotics
    Neurontin / Lyrica
The Conservative Approach
• Physical Therapy
  Conditioning
  Stretching
  Strengthening
  Modalities
    (i.e., heat, ice, ultrasound, electrical
  stimulation)
• Encourages weight loss; improves aerobic
  conditioning
• Lumbosacral corset (soft) or Lumbosacral
  orthosis (rigid)
The Conservative Approach
• Epidural Steroid Injections
  – including:
     • Caudal blocks
     • Central epidural steroids
     • Foraminal epidural steroids
Epidural Steroid Inj (ESI)
•   Staple of conservative management
•   Usually given in a “series” of 3
•   But usually limited to 3 injections in a year
•   Not a long term solution
•   Literature support is limited
The Conservative Approach
• Alternative treatments
  – Chiropractor




  – DRX-9000 (Traction Device)
Questions?
• Who gets surgery, who does not?
• When do we institute conservative
  treatment?
• How long do we pursue a
  conservative route?
• What literature is out there to provide
  guidance?
Who gets what treatment?
Flaniken, Doris        H St. Joseph Regional Health Center
M000473610              LUMBAR SPINE MRI W/O CONTRAST
12/14/1935                                 t2_tse_rst_sag
F                                     2/12/2007 15:27:21
                                               001087049
                                               LOC: -6.87
                                            THK: 4 SP: 4.4
                                                      HFS




A                                                       P
                                                             OR


EC:   0
SE
FA:   170                                         Z: 1.14
TR:   3750                                         C: 110
TE:   115                                         W: 378
                                          Compressed 7 :1
Page: 9 of 15          F                      IM: 9 SE: 2
                                       cm




                    -71 y/o female                                -64 y/o female
                    -Severe claudication                          -Incapacitating LBP
                    -Over weight                                  -N. Claudication
                    -Poor cardiac                                 -Healthy
                    function
                    -Newly diagnosed
                    pulmonary lesion
At what point should conservative
        treatment be used?
• In a perfect world, all non operative
  management is tried prior to the first visit to the
  office
• For certain patients, non surgical means should
  be exhausted prior to surgical consideration
• Initial focus should be on patient education, pain
  control, and getting the patient back to ADL
How long do we give non operative
           treatment?
• Based on each individual patient
  – Symptoms
  – Clinical findings
• The “gut” feeling of the practitioner based
  on experience
Now is the time for the coffee to
            kick in!!!




    BORING RESEARCH DATA ALERT!!
What does the literature say?
• Non operative treatment of LSS w/ 3 year
  outcome analysis by Simotas et al (2000)
• Maine Lumbar Spine Study by Atlas et al
  (2005) – perspective observational study
• A randomized controlled trial for surgical
  vs. non surgical treatment of LSS,
  Malmivaar et al (2006)
Non operative treatment of LSS w/
        3 year analysis
• 49 patients treated non operatively
• Excluded if < 50 y/o and history of
  previous lumbar surgery
• Inclusions were severe back, buttock, and
  leg pain w/ MRI and/or CT evidence of
  single level central LSS
• Methodic regimen of conservative therapy
Non operative treatment of LSS w/
        3 year analysis
• Conservative regimen (each step based
  on outcome of previous treatment)
  – Bed rest
  – Tapered oral corticosteroids
  – Epidural steroid (2 – 3 at physician discretion)
  – NSAIDS for 4 -6 week periods
• Aggressive rehab/PT during above tx
Non operative treatment of LSS w/
        3 year analysis
• Mean F/U 33 months (16 – 55 months)
• conclusion:
  – Authors suggest that conservative treatment
    is a viable option for LSS base on:
     • 25% significant improvement in symptoms and
       satisfaction
     • Rare neurologic deterioration over time of study
• But you decide for your self
          Is 25% acceptable?
Maine Lumbar Spine Study
• 1,4,and 8 to 10 year follow ups
• Patients recruited from various orthopedic,
  neurosurgical, and occupational clinics in
  Maine
• 148 initial patient population
• 81 patients underwent surgical
  decompression
• 67 patients treated non surgically
Maine Lumbar Spine Study
• Moderate findings/ moderate symptoms
• Surgical patients had the worse baseline
  symptoms and function
• Conclusions after 1 year:
  – Best outcomes in the surgical population were
    observed in the first 3 months after surgery
  – No significant change in symptoms were noted in the
    non operative population but also no worsening of
    neurologic function
Maine Lumbar Spine Study
• Conclusions at 4 years:
  – 119 patients remaining
  – 70% of surgical patients report improvement in
    symptoms vs. 52% of non surgical patients
  – 63% of surgical patients satisfied with symptoms vs.
    42% of non surgical patients
  – Moderate decline in the satisfaction of the surgical
    group
  – Conversely, the non operative group moderate
    improvement in symptoms and stability
  – ? convergence
Maine Lumbar Spine Study
• Conclusions at 8 to 10 years:
  – 105 remaining patients at 8 years
  – 97 remaining at 10 years
  – 53% of surgical patients improved
  – 52% of non surgical patients improved
  – 55% of surgical patients satisfied
  – 49% of non surgical patients satisfied
Maine Lumbar Spine Study
• Results were tainted by:
  – 23% of surgical patients required re-operation
  – 39% of non surgical patients underwent at least on
    lumbar surgery
• Ultimately:
  – There was a similarity between the results of the
    initial treatment and the 8/10 F/U
  – Leg pain relief and functional issues still favored initial
    surgical management
A randomized controlled trial for surgical vs. non
           surgical treatment of LSS

• 94 patients
• 50 surgical/ 44 non surgical
• Surgical: segmental decompression w/o
  facetectomy
• Non surgical: under the care of physiatrist
  (NSAIDS and physical therapy. No mention of
  ESI in this report)
• 6 month, 1 year, and 2 year F/Us
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Included:
  – Clinical symptoms of LSS
  – Persistent pain w/o neurological deficit
  – Spinal canal <10mm on MRI
  – Duration of symptoms > 6 months
  – Disease level could be treated either way
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Extensive exclusion list:
   –   Previous surgery
   –   Severe stenosis w/ progressive neurologic deficit
   –   LSS that was too mild (wouldn’t warrant surgery)
   –   Other spinal disorders/pathology
   –   Diabetic neuropathy
   –   Other disorders of the lower limbs
   –   Psychiatric disorders/alcoholism
   –   Diagnosis of herniated lumbar disc in past 12 mon
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Of note:
  – Mean age was 62/63 (ns/s)
  – Majority of both group were retired
  – time of symptoms from onset (yrs): 14/16
  – Most participants in both groups perceived their
    health as poor
  – Exam: neg SLR, low percent of LBP, better w/ lumbar
    FF, >50% decreased vib sense, and >30% had loss
    of AJ reflex
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Results:
  – 4 areas calculated:
     •   Oswestry Disability Index
     •   Leg pain during walking
     •   LBP during walking
     •   Self reported walking distances
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Oswestry Index (disablility) (0 – 100%)
  – Ref. 0-20% stbl/no tx, 21-40% mod/cons tx
  – At 24 months: (NS) 29% vs (S) 21%
• Leg pain w/ walking (@ 24 months)
  – 0 – 10 pain scale
  – 4.5 (NS) vs. 3 (S)
• LBP w/ walking (@ 24 m, same scale)
  – ~5 (NS) vs. ~2.5 (S)
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Self reported walking distances
  – At 1 year F/U
     • 1.28 miles (NS) vs. 1.38 miles (S)
  – At 2 year F/U
     • 1.26 miles (NS) vs. 1.29 miles (S)
  – Not a very significant difference in distance
    from one group to the other
A randomized controlled trial for surgical vs.
      non surgical treatment of LSS
• Conclusions:
  – Surgical patients did better in terms of
    disability, leg pain, and LBP
  – Walking distance was not clinically significant
    as noted
  – There was meaningful recovery in the non
    surgical group
  – Supports surgical decompression after
    exhaustion of conservative treatments
My Conclusions
• Simply:
  – Each patient represents a different set of
    circumstances regarding their level and
    tolerance of pain and disability
  – Finding on studies and neurological deficit
    tend to push surgeons to offer decompression
  – BUT patients are motivated more by how they
    feel and what they are willing to tolerate
My Conclusions
• Moreover:
  – Studies have proven efficacy of conservative
    management for patients with LSS
  – When to institute non operative therapy and
    once started, when to stop are not well
    outlined for the practitioner
  – Individual conservative measures need to be
    studied better
My Conclusions

• So FINALLY:

  – Nothing short of surgical decompression will
    structurally change the diameter of the stenotic
    segment
  – Although extensive studies have proven the worth of
    conservative management for LSS, most came up
    short of providing data that allows the practitioner to
    make a confident decision
Thank You

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Current treatment of lumbar stenosis

  • 1. Lumbar Spinal Stenosis Conservative Management for the “Simple” Minded Practitioner By Joe Hlavin PA-C
  • 2. The Only Way To Heal Is With Ice Cold Steal
  • 3. Conservative Management of LSS is Anything and Everything Other than the Last Slide And when the patient in your office tells you: I don’t want surgery, you might look like this…
  • 4.
  • 6. Current Treatment of Lumbar Stenosis Role of Non-Operative Management By Joseph Hlavin PA-C
  • 7. Goals of this Presentation (BUT Not to bore you) • Quickly – Review the clinical presentation of LSS – Review causes of LSS • List the different conservative treatments available • Propose a debate on when it is reasonable to offer conservative management over surgery • Offer articles/studies as a guide for who, when and for how long
  • 8. Overview 1. Hypertrophy of the Yellow Ligament 2. Flattening/bulging disc 3. Facet Hypertrophy 4. Foraminal Stenosis 5. Canal Stenosis
  • 9. Hallmark Symptoms • Neurogenic Claudication • +/- Lower back pain • +/- hip and/or radicular pain • Improvement of pain with forward flexion of the lumbar spine: – Shopping cart sign – Easier walking up hill
  • 10. Neurogenic Claudication • Not to be confused with Vascular Claudication – Neurogenic: • Symptoms w/ walking AND standing • Variable walking distance w/o symptoms • Relief w/ sitting & flexion • Lower extremity pulses OK
  • 11. Neurogenic Claudication – Vascular Claudication • Symptoms w/ walking BUT NOT standing • NO variability in walking distance prior to onset of symptoms • NO relief with lumbar flexion • Diminished pulses in feet
  • 12. Degenerative Lumbar Stenosis • Age related: (Spondylosis) – Spondylosis – Degeneration of the facet joints – Degenerative spondylolithesis – Facet arthropathy – Degenerative disc bulge/spur – Hypertrophic ligamentum flavum
  • 13. Stenosis to a Degree • Mild • Moderate • Severe
  • 15. Lumbar Stenosis - Moderate
  • 16. Lumbar Stenosis - Severe Flaniken, Doris H St. Joseph Regional Health Center St. M000473610 LUMBAR SPINE MRI W/O CONTRAST Flaniken, Doris A St. Joseph Regional Health Center 12/14/1935 Regional t2_tse_rst_sag M000473610 LUMBAR SPINE MRI W/O CONTRAST F 2/12/2007 15:27:21 001087049 12/14/1935 t2_tse_rst_tra_msma F 2/12/2007 15:40:26 LOC: -6.87 001087049 THK: 4 SP: 4.4 HFS LOC: -100.81 THK: 4 SP: 4.4 HFS R L A P EC: 0 SE FA: 180 L4-5 Z: 1.60 TR: 8830 C: 314 TE: 86 W: 708 EC: 0 Compressed 7 :1 SE FA: 170 Z: 1.14 Page: 32 of 39 P IM: 32 SE: 4 TR: 3750 C: 110 cm 3750 TE: 115 W: 378 Compressed 7 :1 Page: 9 of 15 F IM: 9 SE: 2 cm
  • 17. Lumbar Stenosis – Other Causes • Causes of non- arthritic lumbar canal stenosis: – Disc rupture – Tumor – Abscess – Hematoma – Trauma/FX
  • 21. The Conservative Approach • Medications – NSAIDs Acetaminophen Oral corticosteroids Muscle relaxants Narcotics Neurontin / Lyrica
  • 22. The Conservative Approach • Physical Therapy Conditioning Stretching Strengthening Modalities (i.e., heat, ice, ultrasound, electrical stimulation) • Encourages weight loss; improves aerobic conditioning • Lumbosacral corset (soft) or Lumbosacral orthosis (rigid)
  • 23. The Conservative Approach • Epidural Steroid Injections – including: • Caudal blocks • Central epidural steroids • Foraminal epidural steroids
  • 24. Epidural Steroid Inj (ESI) • Staple of conservative management • Usually given in a “series” of 3 • But usually limited to 3 injections in a year • Not a long term solution • Literature support is limited
  • 25. The Conservative Approach • Alternative treatments – Chiropractor – DRX-9000 (Traction Device)
  • 26. Questions? • Who gets surgery, who does not? • When do we institute conservative treatment? • How long do we pursue a conservative route? • What literature is out there to provide guidance?
  • 27. Who gets what treatment? Flaniken, Doris H St. Joseph Regional Health Center M000473610 LUMBAR SPINE MRI W/O CONTRAST 12/14/1935 t2_tse_rst_sag F 2/12/2007 15:27:21 001087049 LOC: -6.87 THK: 4 SP: 4.4 HFS A P OR EC: 0 SE FA: 170 Z: 1.14 TR: 3750 C: 110 TE: 115 W: 378 Compressed 7 :1 Page: 9 of 15 F IM: 9 SE: 2 cm -71 y/o female -64 y/o female -Severe claudication -Incapacitating LBP -Over weight -N. Claudication -Poor cardiac -Healthy function -Newly diagnosed pulmonary lesion
  • 28. At what point should conservative treatment be used? • In a perfect world, all non operative management is tried prior to the first visit to the office • For certain patients, non surgical means should be exhausted prior to surgical consideration • Initial focus should be on patient education, pain control, and getting the patient back to ADL
  • 29. How long do we give non operative treatment? • Based on each individual patient – Symptoms – Clinical findings • The “gut” feeling of the practitioner based on experience
  • 30. Now is the time for the coffee to kick in!!! BORING RESEARCH DATA ALERT!!
  • 31. What does the literature say? • Non operative treatment of LSS w/ 3 year outcome analysis by Simotas et al (2000) • Maine Lumbar Spine Study by Atlas et al (2005) – perspective observational study • A randomized controlled trial for surgical vs. non surgical treatment of LSS, Malmivaar et al (2006)
  • 32. Non operative treatment of LSS w/ 3 year analysis • 49 patients treated non operatively • Excluded if < 50 y/o and history of previous lumbar surgery • Inclusions were severe back, buttock, and leg pain w/ MRI and/or CT evidence of single level central LSS • Methodic regimen of conservative therapy
  • 33. Non operative treatment of LSS w/ 3 year analysis • Conservative regimen (each step based on outcome of previous treatment) – Bed rest – Tapered oral corticosteroids – Epidural steroid (2 – 3 at physician discretion) – NSAIDS for 4 -6 week periods • Aggressive rehab/PT during above tx
  • 34. Non operative treatment of LSS w/ 3 year analysis • Mean F/U 33 months (16 – 55 months) • conclusion: – Authors suggest that conservative treatment is a viable option for LSS base on: • 25% significant improvement in symptoms and satisfaction • Rare neurologic deterioration over time of study • But you decide for your self Is 25% acceptable?
  • 35. Maine Lumbar Spine Study • 1,4,and 8 to 10 year follow ups • Patients recruited from various orthopedic, neurosurgical, and occupational clinics in Maine • 148 initial patient population • 81 patients underwent surgical decompression • 67 patients treated non surgically
  • 36. Maine Lumbar Spine Study • Moderate findings/ moderate symptoms • Surgical patients had the worse baseline symptoms and function • Conclusions after 1 year: – Best outcomes in the surgical population were observed in the first 3 months after surgery – No significant change in symptoms were noted in the non operative population but also no worsening of neurologic function
  • 37. Maine Lumbar Spine Study • Conclusions at 4 years: – 119 patients remaining – 70% of surgical patients report improvement in symptoms vs. 52% of non surgical patients – 63% of surgical patients satisfied with symptoms vs. 42% of non surgical patients – Moderate decline in the satisfaction of the surgical group – Conversely, the non operative group moderate improvement in symptoms and stability – ? convergence
  • 38. Maine Lumbar Spine Study • Conclusions at 8 to 10 years: – 105 remaining patients at 8 years – 97 remaining at 10 years – 53% of surgical patients improved – 52% of non surgical patients improved – 55% of surgical patients satisfied – 49% of non surgical patients satisfied
  • 39. Maine Lumbar Spine Study • Results were tainted by: – 23% of surgical patients required re-operation – 39% of non surgical patients underwent at least on lumbar surgery • Ultimately: – There was a similarity between the results of the initial treatment and the 8/10 F/U – Leg pain relief and functional issues still favored initial surgical management
  • 40. A randomized controlled trial for surgical vs. non surgical treatment of LSS • 94 patients • 50 surgical/ 44 non surgical • Surgical: segmental decompression w/o facetectomy • Non surgical: under the care of physiatrist (NSAIDS and physical therapy. No mention of ESI in this report) • 6 month, 1 year, and 2 year F/Us
  • 41. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Included: – Clinical symptoms of LSS – Persistent pain w/o neurological deficit – Spinal canal <10mm on MRI – Duration of symptoms > 6 months – Disease level could be treated either way
  • 42. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Extensive exclusion list: – Previous surgery – Severe stenosis w/ progressive neurologic deficit – LSS that was too mild (wouldn’t warrant surgery) – Other spinal disorders/pathology – Diabetic neuropathy – Other disorders of the lower limbs – Psychiatric disorders/alcoholism – Diagnosis of herniated lumbar disc in past 12 mon
  • 43. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Of note: – Mean age was 62/63 (ns/s) – Majority of both group were retired – time of symptoms from onset (yrs): 14/16 – Most participants in both groups perceived their health as poor – Exam: neg SLR, low percent of LBP, better w/ lumbar FF, >50% decreased vib sense, and >30% had loss of AJ reflex
  • 44. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Results: – 4 areas calculated: • Oswestry Disability Index • Leg pain during walking • LBP during walking • Self reported walking distances
  • 45. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Oswestry Index (disablility) (0 – 100%) – Ref. 0-20% stbl/no tx, 21-40% mod/cons tx – At 24 months: (NS) 29% vs (S) 21% • Leg pain w/ walking (@ 24 months) – 0 – 10 pain scale – 4.5 (NS) vs. 3 (S) • LBP w/ walking (@ 24 m, same scale) – ~5 (NS) vs. ~2.5 (S)
  • 46. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Self reported walking distances – At 1 year F/U • 1.28 miles (NS) vs. 1.38 miles (S) – At 2 year F/U • 1.26 miles (NS) vs. 1.29 miles (S) – Not a very significant difference in distance from one group to the other
  • 47. A randomized controlled trial for surgical vs. non surgical treatment of LSS • Conclusions: – Surgical patients did better in terms of disability, leg pain, and LBP – Walking distance was not clinically significant as noted – There was meaningful recovery in the non surgical group – Supports surgical decompression after exhaustion of conservative treatments
  • 48. My Conclusions • Simply: – Each patient represents a different set of circumstances regarding their level and tolerance of pain and disability – Finding on studies and neurological deficit tend to push surgeons to offer decompression – BUT patients are motivated more by how they feel and what they are willing to tolerate
  • 49. My Conclusions • Moreover: – Studies have proven efficacy of conservative management for patients with LSS – When to institute non operative therapy and once started, when to stop are not well outlined for the practitioner – Individual conservative measures need to be studied better
  • 50. My Conclusions • So FINALLY: – Nothing short of surgical decompression will structurally change the diameter of the stenotic segment – Although extensive studies have proven the worth of conservative management for LSS, most came up short of providing data that allows the practitioner to make a confident decision