This issue brief discusses students with disabilities who are at greatest risk of poor employment outcomes after high school. Research has found that students with disabilities often have difficulty finding employment after leaving school. The brief aims to identify specific risk factors for poor employment through analysis of a national dataset. It also seeks to determine what schools can do to help mitigate risks, such as increasing vocational education and integration with non-disabled peers. The goal is to generate new knowledge that can inform more effective school interventions to improve postschool job prospects for high-risk students.