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Radiologial Anatomy of Brain
-Dr Bishnu Khatiwada
MD Resident
Radiodiagnosis, NAMS
Kathmandu Nepal
Cerebral Hemispheres
• Cortical grey matter
• White matter- Projection, Association &
Commissural fibers
• Basal ganglia
• Thalamus
• Hypothalamus
• Pituitary gland
• Limbic lobe- Cingulate, hippocampus, splenial
& parahippocampal gyri, fornix
Lateral surface of cerebral hemispheres
Medial surface of cerebral hemisphere
Basal ganglia
Subcortical grey matter
Internal capsule
Corpus Callosum
Large midline mass of commissural fibers which
connects corresponding areas of both hemispheres
(10cm long & progressively thicker towards
posteriorly)
4 parts of corpus callosum
Pituitary gland
• Lies in pituitary fossa
• Size: 12x9x8mm (Pineal gland: 7x6x3mm)
• Anterior lobe is 5 times larger than the
posterior lobe
• Anterior lobe develops from Rathke’s pouch in
the roof of primitive mouth (A tumor from
remnants of the epithelium of this pouch is
called Craniopharyngioma)
• Anterior lobe is adherent to the posterior lobe
by a narrow zone called pars intermedia
Ventricular System
Lateral Ventricles
Normal Dimensions
• Frontal horn of LV at the level of foramen Monro:
– <40yrs: <12mm
– >40yrs: <15mm
• Ventriculo-hemispheric ratio:
– <33% in adults
– <40% in children.
• Width of 3rd ventricle:
<5mm-children
<7mm-<60 yrs
<9mm->60 yrs
Fourth ventricle
• Situated between pons and upper half of
medulla infront and cerebellum behind.
• 3 openings
• Median aperture of Magendie-situated in
lower part of roof
• 2 Lateral apertures of Luschka- at the end of
each lateral recess
• CSF from the ventricular system passes
through these apertures into SA spaces
Cerebellum
Cisterns
• Large CSF filled Subarachnoid spaces at certain
places
• Acts as the cushion around the medulla and
other brain structures
• Have the density of CSF
Suprasellar Cistern
• Suprasellar cistern comprises interpeduncular
cistern posteriorly, crural and ambient cistern
posterolaterally, sylvian cistern anterolaterally
and chiasmatic cistern anteriorly
• It looks like a Star of David or Pentagon. The
corners of the pentagon are made of
interhemispheric fissure anteriorly, sylvian
fissure anterolaterally, ambient cisterns
postlaterally
Sectional Anatomy
CT Technique
• Routine – Axial axis with 15-20’ angulation to
canthomeatal line
• Reviewed from caudal to cephalic levels
• 8-10mm thick sections routinely obtained
• 1.5-3mm thinner sections- Orbit, pituitary
gland, supra & parasellar region and CPA
MRI technique
• Routine- Axial , coronal & less often sagittal
axes of 5 -10 mm thickness
• Routinely T1 & T2 axial and T2 coronal studies
.
• Axial scans obtained parallel to canthomeatal
line
• Sellar & post fossa regions –sagittal & coronal
images of 2-4 mm thickness.
Axial sections
• Infratentorial Cuts:
Below the fourth ventricle
Level of the fourth ventricle
Above the fourth ventricle
• Supratentorial Cuts:
Third Ventricular Level
Low Ventricular Level
Mid-ventricular Level
Above the Ventricles
Posterior Fossa
• Outlined by Clivus , Petrous bone and occipital
bone. Superiorly- Tentorium cerebelli
• Divided by 4th ventricle into anterior &
posterior compartments:
Ant (1/3rd) Brainstem
Post (2/3rd) Cerebellum
Below the Fourth ventricle level
• Medulla
• Cerebellar tonsils
• Cerebellar hemispheres
• Cisterna magna
• Vertebral arteries
• Base of the skull structures (foramina if wide
window setting)
• Orbital contents
Fourth Ventricular Level
• Fourth ventricle with choroid plexus
• Lower pons
• Middle cerebellar peduncles
• Anterior and lateral mesencephalic cisterns
• Nodulous
• Cerebellar hemispheres
Above the Fourth Ventricle Level
• Midline vermis
• Cerebellar hemispheres
• Mesencephalon
• Temporal lobes
• Sylvian fissure
• Frontal lobe
• Suprasellar cistern containing ICA, infundibulum,
optic chiasma, mammillary bodies, top of basilar
artery
Supratentorial Level
Third Ventricular level
• Third ventricle- in the midline
• Inferior parts of frontal lobes
• Sylvian fissure
• Insular cortex
• External capsule
• Putamen and globus pallidus
• Internal capsule
• Midbrain with quadrigeminal plates and cistern
Low Ventricular Level
• Superior portion of frontal horns of lateral ventricles
• Head of caudate nucleus
• Genu of the corpus callosum
• Cingulate sulcus and gyrus
• Pineal gland
• Habenula
• Great vein of Galen
• Straight sinus
Midventricular level
• Superior extension of Sylvian fissure
• Most superior portion of frontal horns
• Corpus callosum
• Caudate nucleus
• Occipital horns
Above the Ventricular level
• Frontal and parietal lobes
• Small portion of occipital lobe
• Central sulcus in mid portion of scan – deeper
sulcus
• Pre and post central gyri
• Interhemispheric fissure with falx
Coronal Scans
• Frontal Horn Level
• Third Ventricular Level
• Midbrain level
• Mid-4th ventricular Level
• Occipital Horn Level
Mid-Sagittal Scan
Physiological calcifications
• Chroid plexus
• Basal ganglia
• Pineal gland and habenula
• Falx calcification
• Dentate nuclei
Physiological calcifications
References
• CT and MRI of The Whole Body, John R.
Haaga, 6th edition
• Anatomy for Diagnostic Imaging, Stephanie
Ryan, 3rd edition
• Clinical Neuroanatomy, Richard S. Snell, 7th
edition
Questions
• Show the genu and splenium of corpus callosum
• 10 sites of physiological calcification
• Differences between physiological calcification versus
bleed
• Difference between habenular and pineal
calcification
• Size of pineal gland and pituitary gland
• What are the recesses of third ventricle?
Thank You!!

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CT and MRI anatomy of brain

  • 1. Radiologial Anatomy of Brain -Dr Bishnu Khatiwada MD Resident Radiodiagnosis, NAMS Kathmandu Nepal
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  • 4. Cerebral Hemispheres • Cortical grey matter • White matter- Projection, Association & Commissural fibers • Basal ganglia • Thalamus • Hypothalamus • Pituitary gland • Limbic lobe- Cingulate, hippocampus, splenial & parahippocampal gyri, fornix
  • 5. Lateral surface of cerebral hemispheres
  • 6. Medial surface of cerebral hemisphere
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  • 12. Corpus Callosum Large midline mass of commissural fibers which connects corresponding areas of both hemispheres (10cm long & progressively thicker towards posteriorly)
  • 13. 4 parts of corpus callosum
  • 14. Pituitary gland • Lies in pituitary fossa • Size: 12x9x8mm (Pineal gland: 7x6x3mm) • Anterior lobe is 5 times larger than the posterior lobe • Anterior lobe develops from Rathke’s pouch in the roof of primitive mouth (A tumor from remnants of the epithelium of this pouch is called Craniopharyngioma) • Anterior lobe is adherent to the posterior lobe by a narrow zone called pars intermedia
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  • 18. Normal Dimensions • Frontal horn of LV at the level of foramen Monro: – <40yrs: <12mm – >40yrs: <15mm • Ventriculo-hemispheric ratio: – <33% in adults – <40% in children. • Width of 3rd ventricle: <5mm-children <7mm-<60 yrs <9mm->60 yrs
  • 19. Fourth ventricle • Situated between pons and upper half of medulla infront and cerebellum behind. • 3 openings • Median aperture of Magendie-situated in lower part of roof • 2 Lateral apertures of Luschka- at the end of each lateral recess • CSF from the ventricular system passes through these apertures into SA spaces
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  • 22. Cisterns • Large CSF filled Subarachnoid spaces at certain places • Acts as the cushion around the medulla and other brain structures • Have the density of CSF
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  • 24. Suprasellar Cistern • Suprasellar cistern comprises interpeduncular cistern posteriorly, crural and ambient cistern posterolaterally, sylvian cistern anterolaterally and chiasmatic cistern anteriorly • It looks like a Star of David or Pentagon. The corners of the pentagon are made of interhemispheric fissure anteriorly, sylvian fissure anterolaterally, ambient cisterns postlaterally
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  • 27. CT Technique • Routine – Axial axis with 15-20’ angulation to canthomeatal line • Reviewed from caudal to cephalic levels • 8-10mm thick sections routinely obtained • 1.5-3mm thinner sections- Orbit, pituitary gland, supra & parasellar region and CPA
  • 28. MRI technique • Routine- Axial , coronal & less often sagittal axes of 5 -10 mm thickness • Routinely T1 & T2 axial and T2 coronal studies . • Axial scans obtained parallel to canthomeatal line • Sellar & post fossa regions –sagittal & coronal images of 2-4 mm thickness.
  • 29. Axial sections • Infratentorial Cuts: Below the fourth ventricle Level of the fourth ventricle Above the fourth ventricle • Supratentorial Cuts: Third Ventricular Level Low Ventricular Level Mid-ventricular Level Above the Ventricles
  • 30. Posterior Fossa • Outlined by Clivus , Petrous bone and occipital bone. Superiorly- Tentorium cerebelli • Divided by 4th ventricle into anterior & posterior compartments: Ant (1/3rd) Brainstem Post (2/3rd) Cerebellum
  • 31. Below the Fourth ventricle level • Medulla • Cerebellar tonsils • Cerebellar hemispheres • Cisterna magna • Vertebral arteries • Base of the skull structures (foramina if wide window setting) • Orbital contents
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  • 34. Fourth Ventricular Level • Fourth ventricle with choroid plexus • Lower pons • Middle cerebellar peduncles • Anterior and lateral mesencephalic cisterns • Nodulous • Cerebellar hemispheres
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  • 36.
  • 37. Above the Fourth Ventricle Level • Midline vermis • Cerebellar hemispheres • Mesencephalon • Temporal lobes • Sylvian fissure • Frontal lobe • Suprasellar cistern containing ICA, infundibulum, optic chiasma, mammillary bodies, top of basilar artery
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  • 42. Third Ventricular level • Third ventricle- in the midline • Inferior parts of frontal lobes • Sylvian fissure • Insular cortex • External capsule • Putamen and globus pallidus • Internal capsule • Midbrain with quadrigeminal plates and cistern
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  • 46. Low Ventricular Level • Superior portion of frontal horns of lateral ventricles • Head of caudate nucleus • Genu of the corpus callosum • Cingulate sulcus and gyrus • Pineal gland • Habenula • Great vein of Galen • Straight sinus
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  • 50. Midventricular level • Superior extension of Sylvian fissure • Most superior portion of frontal horns • Corpus callosum • Caudate nucleus • Occipital horns
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  • 53. Above the Ventricular level • Frontal and parietal lobes • Small portion of occipital lobe • Central sulcus in mid portion of scan – deeper sulcus • Pre and post central gyri • Interhemispheric fissure with falx
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  • 57. Coronal Scans • Frontal Horn Level • Third Ventricular Level • Midbrain level • Mid-4th ventricular Level • Occipital Horn Level
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  • 65. Physiological calcifications • Chroid plexus • Basal ganglia • Pineal gland and habenula • Falx calcification • Dentate nuclei
  • 67. References • CT and MRI of The Whole Body, John R. Haaga, 6th edition • Anatomy for Diagnostic Imaging, Stephanie Ryan, 3rd edition • Clinical Neuroanatomy, Richard S. Snell, 7th edition
  • 68. Questions • Show the genu and splenium of corpus callosum • 10 sites of physiological calcification • Differences between physiological calcification versus bleed • Difference between habenular and pineal calcification • Size of pineal gland and pituitary gland • What are the recesses of third ventricle?