This document discusses a teaching activity about sickle cell anemia. It begins with an introduction to sickle cell anemia and outlines two key activities for students - a "mystery of the crooked cell" activity where students must hypothesize the cause of sickle cell anemia using a case study and lab stations. It concludes with a WHO summit narrative where students present as scientists from different countries on the state of sickle cell anemia and examples of educational materials and experiments they designed. The document explains that the activity engages students by addressing a real-world medical issue through science, collaboration, and problem-solving to help humans.