A presentation I gave in the International Institute of Molecular and Cell Biology in Warsaw, Poland on February 10, 2010. It describes the features of the CompaRNA server (http://comparna.amu.edu.pl/).
7-12 Compare/Order Fractions & Mixed #sRudy Alfonso
The document provides steps to order fractions and mixed numbers from least to greatest. It reviews finding the LCM of denominators to determine the LCD. It shows setting up new denominators using the LCD and finding equivalent fractions using "the rule". The example problem walks through ordering the fractions 1/2, 5/8, 3/4 by finding the LCM of the denominators, setting up new denominators, finding equivalent fractions, and determining the order is 1/2, 3/4, 5/8 from least to greatest.
The 90/10 principle states that 10% of life is made up of external events outside of our control, while 90% is determined by our internal reactions to what happens. How we react to situations, both positive and negative, has a significant impact on our experiences and outcomes. The document provides an example of how having a bad reaction to a spilled cup of coffee can negatively impact one's whole day, while responding calmly would lead to a better outcome. It encourages readers to apply this principle by not letting external events ruin their day through overreacting, but instead focusing on controlling their internal reactions.
GlobalInvacom's fibre optic technology called FibreIRS has been very successful, connecting over 2 million households in the past 5 years. Their newest system, the O2E Converter, allows up to 4,096 connections from a single satellite dish. Sales of fibre optic products have increased 20% annually, with northern Europe being the largest market at 40-50% of sales. GlobalInvacom continues developing new fibre optic products and systems to expand connectivity capabilities.
Marcos Benni has opened a new office in Jundiai, Brazil to expand his digital TV forum BSD and start an online store for digital TV products. The 140 square meter office includes a reception area, TV studio for creating product videos, and satellite dishes for testing reception. Benni's BSD forum reaches 400,000 readers monthly, making it one of Brazil's largest. From his new office, Benni plans to launch bsdshop.com.br featuring video demonstrations of satellites dishes, LNBs, receivers and other gear. He will also continue updating his popular forum with reception news and run an IPTV and radio station.
The Amiko Mini HD is a compact satellite receiver measuring 15x11x3.5 cm. It has all the features of larger receivers, including a PVR, HDMI output up to 1080p, USB ports, and network features like YouTube. The receiver can automatically detect satellites and has a blind scan function to find all channels. It also supports fast scanning of channels from several European providers. The intuitive OSD allows easy management of live and recorded content.
7-12 Compare/Order Fractions & Mixed #sRudy Alfonso
The document provides steps to order fractions and mixed numbers from least to greatest. It reviews finding the LCM of denominators to determine the LCD. It shows setting up new denominators using the LCD and finding equivalent fractions using "the rule". The example problem walks through ordering the fractions 1/2, 5/8, 3/4 by finding the LCM of the denominators, setting up new denominators, finding equivalent fractions, and determining the order is 1/2, 3/4, 5/8 from least to greatest.
The 90/10 principle states that 10% of life is made up of external events outside of our control, while 90% is determined by our internal reactions to what happens. How we react to situations, both positive and negative, has a significant impact on our experiences and outcomes. The document provides an example of how having a bad reaction to a spilled cup of coffee can negatively impact one's whole day, while responding calmly would lead to a better outcome. It encourages readers to apply this principle by not letting external events ruin their day through overreacting, but instead focusing on controlling their internal reactions.
GlobalInvacom's fibre optic technology called FibreIRS has been very successful, connecting over 2 million households in the past 5 years. Their newest system, the O2E Converter, allows up to 4,096 connections from a single satellite dish. Sales of fibre optic products have increased 20% annually, with northern Europe being the largest market at 40-50% of sales. GlobalInvacom continues developing new fibre optic products and systems to expand connectivity capabilities.
Marcos Benni has opened a new office in Jundiai, Brazil to expand his digital TV forum BSD and start an online store for digital TV products. The 140 square meter office includes a reception area, TV studio for creating product videos, and satellite dishes for testing reception. Benni's BSD forum reaches 400,000 readers monthly, making it one of Brazil's largest. From his new office, Benni plans to launch bsdshop.com.br featuring video demonstrations of satellites dishes, LNBs, receivers and other gear. He will also continue updating his popular forum with reception news and run an IPTV and radio station.
The Amiko Mini HD is a compact satellite receiver measuring 15x11x3.5 cm. It has all the features of larger receivers, including a PVR, HDMI output up to 1080p, USB ports, and network features like YouTube. The receiver can automatically detect satellites and has a blind scan function to find all channels. It also supports fast scanning of channels from several European providers. The intuitive OSD allows easy management of live and recorded content.
Here are the definitions for this week's vocabulary words:
Election - An organized competition to choose someone for a position or office.
Campaign - How people work to gain support for someone running for an office or position.
Represent - To speak or act for someone else.
Candidate - A person who is seeking an office or position.
Confidence - Belief in one's ability to do something well.
Let me know if you need any clarification or have additional questions!
The document discusses the importance of developing a strategic communications approach versus relying solely on tactics. It argues that a strategic approach requires thorough research, understanding your brand and audience, developing integrated communication plans with clear goals and measurements, and coordinating tactical execution. An agency model is suggested where communication teams serve as internal consultants who understand strengths, research needs, develop strategic plans, and ensure tactics align with institutional brand and goals. Evaluating impact is key to proving effectiveness and value.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise boosts blood flow and levels of neurotransmitters and endorphins which elevate and stabilize mood.
2-9 Adding and Subtracting Greater Whole NumbersRudy Alfonso
The document provides step-by-step instructions for adding and subtracting greater whole numbers. It demonstrates how to:
1) Line up numbers properly when adding or subtracting.
2) Work through addition or subtraction problems step-by-step by adding/subtracting ones, tens, hundreds, etc. and regrouping when needed.
3) Explain the process of solving multi-step addition and subtraction problems through worked examples.
Direct Hospitality provides consulting services for hotels, pubs, clubs, restaurants, and cafes in Australia and overseas. Their services include operational support, kitchen and floor layout development, concept development, menu planning, cost control, inventory management, first aid and responsible service of alcohol training, budgeting, marketing, gaming machine management, mystery shopper programs, and interim management. They also offer ATM services to increase customer traffic and sales.
Presentatie tijdens Groen Gras over de wijzigingen die de Wet werk en zekerheid met zich meebrengt. Op 1 januari 2015 gaat het eerste gedeelte van de nieuwe Wet werk en zekerheid in. Dat heeft grote gevolgen voor het personeelsbeleid. Bijvoorbeeld als u vaak uitzendkrachten inzet, maar ook voor de proeftijd bij tijdelijke contracten. Tijdens de bootcamp op Groen Gras praatten wij ondernemers bij.
The document discusses different uses of commas in sentences, including using commas to separate items in a series of three or more items, placing commas after long introductory phrases or clauses but not short ones, using commas and conjunctions to join independent clauses in compound sentences, and setting off interjections with commas unless an exclamation point follows.
This project required that students create a triptych that showed their relationship to the natural world through 3 self-portraits: one depicting themselves as biologically part of nature, a second as a hybrid between human and non-human and a third exploring what they thought will be the fate of global environment.
After a century of war and religious conflict, France was ruled by the powerful King Louis XIV. He weakened the nobility and increased the power of the royal family. Louis lived lavishly and built the magnificent palace at Versailles as a symbol of his authority. However, his attempts to expand French territory through warfare led the country into major debt by the end of his reign.
Here are the definitions for this week's vocabulary words:
Election - An organized competition to choose someone for a position or office.
Campaign - How people work to gain support for someone running for an office or position.
Represent - To speak or act for someone else.
Candidate - A person who is seeking an office or position.
Confidence - Belief in one's ability to do something well.
Let me know if you need any clarification or have additional questions!
The document discusses the importance of developing a strategic communications approach versus relying solely on tactics. It argues that a strategic approach requires thorough research, understanding your brand and audience, developing integrated communication plans with clear goals and measurements, and coordinating tactical execution. An agency model is suggested where communication teams serve as internal consultants who understand strengths, research needs, develop strategic plans, and ensure tactics align with institutional brand and goals. Evaluating impact is key to proving effectiveness and value.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise boosts blood flow and levels of neurotransmitters and endorphins which elevate and stabilize mood.
2-9 Adding and Subtracting Greater Whole NumbersRudy Alfonso
The document provides step-by-step instructions for adding and subtracting greater whole numbers. It demonstrates how to:
1) Line up numbers properly when adding or subtracting.
2) Work through addition or subtraction problems step-by-step by adding/subtracting ones, tens, hundreds, etc. and regrouping when needed.
3) Explain the process of solving multi-step addition and subtraction problems through worked examples.
Direct Hospitality provides consulting services for hotels, pubs, clubs, restaurants, and cafes in Australia and overseas. Their services include operational support, kitchen and floor layout development, concept development, menu planning, cost control, inventory management, first aid and responsible service of alcohol training, budgeting, marketing, gaming machine management, mystery shopper programs, and interim management. They also offer ATM services to increase customer traffic and sales.
Presentatie tijdens Groen Gras over de wijzigingen die de Wet werk en zekerheid met zich meebrengt. Op 1 januari 2015 gaat het eerste gedeelte van de nieuwe Wet werk en zekerheid in. Dat heeft grote gevolgen voor het personeelsbeleid. Bijvoorbeeld als u vaak uitzendkrachten inzet, maar ook voor de proeftijd bij tijdelijke contracten. Tijdens de bootcamp op Groen Gras praatten wij ondernemers bij.
The document discusses different uses of commas in sentences, including using commas to separate items in a series of three or more items, placing commas after long introductory phrases or clauses but not short ones, using commas and conjunctions to join independent clauses in compound sentences, and setting off interjections with commas unless an exclamation point follows.
This project required that students create a triptych that showed their relationship to the natural world through 3 self-portraits: one depicting themselves as biologically part of nature, a second as a hybrid between human and non-human and a third exploring what they thought will be the fate of global environment.
After a century of war and religious conflict, France was ruled by the powerful King Louis XIV. He weakened the nobility and increased the power of the royal family. Louis lived lavishly and built the magnificent palace at Versailles as a symbol of his authority. However, his attempts to expand French territory through warfare led the country into major debt by the end of his reign.
1. bioinformatics.amu.edu.pl
CompaRNA: a server for continuous benchmarking
of automated methods for RNA structure prediction
Tomasz Puton, M.Sc.
Bioinformatics Laboratory
Institute of Molecular Biology and Biotechnology
Faculty of Biology
Adam Mickiewicz University
2. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Outline of the presentation:
1) What is CompaRNA?
2) CompaRNA features
3) Future perspectives
4) Acknowledgements
3. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Outline of the presentation:
1) What is CompaRNA?
2) CompaRNA features
3) Future perspectives
4) Acknowledgements
4. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
The CompaRNA server
A continuous benchmark of automated standalone and
web server methods for RNA secondary structure prediction.
5. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
The CompaRNA server
A continuous benchmark of automated standalone and
web server methods for RNA secondary structure prediction.
Equivalent of Livebench (http://meta.bioinfo.pl/livebench.pl)
in the field of RNA structure predition.
6. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
The CompaRNA server
A continuous benchmark of automated standalone and
web server methods for RNA secondary structure prediction.
Equivalent of Livebench (http://meta.bioinfo.pl/livebench.pl)
in the field of RNA structure predition.
The aim of CompaRNA is to assess the state of the art in the field,
provide a detailed picture of what is possible with the available tools,
where the progress is made and what major problems remain.
7. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
8. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
Experimentally solved RNA structures
9. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
10. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
RNA 2D METHODS
11. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
Predictions
RNA 2D METHODS
12. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
Predictions Rankings
RNA 2D METHODS
13. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
Predictions Rankings
RNA 2D METHODS
WWW
14. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
Predictions Rankings
RNA 2D METHODS
WWW
15. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
Predictions Rankings
Reference RNA secondary structures
RNA 2D METHODS
WWW
16. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
New RNAs
CompaRNA
ENGINE
RNA sequences Experimentally solved RNA structures
RNAVIEW *
Predictions Rankings
Reference RNA secondary structures
RNA 2D METHODS
WWW
* Yang H, Jossinet F, Leontis N, Chen L, Westbrook J, Berman H, Westhof E. (2003):
Tools for the automatic identification and classification of RNA base pairs. Nucleic Acids Res. 31(13):3450-60.
17. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
CompaRNA has automatically extracted 212 RNA structures
(785 RNA chains) since February, 28 2009 from the weekly
updates of the Protein Data Bank.
18. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
CompaRNA has automatically extracted 212 RNA structures
(785 RNA chains) since February, 28 2009 from the weekly
updates of the Protein Data Bank.
357 RNA chains extracted by CompaRNA were bound to
protein chains (428 RNA chains were unbound).
19. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
14 methods predicting RNA secondary structure are tested,
including:
- Mfold
- Sfold
- Contrafold
- HotKnots, PknotsRG (can predict pseudoknots)
- McQFold
20. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
8005 secondary structure predictions have been obtained
for 785 RNA chains solved experimentally.
21. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
8005 secondary structure predictions have been obtained
for 785 RNA chains solved experimentally.
14 methods * 785 seqs of RNA chains = 10990
22. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
8005 secondary structure predictions have been obtained
for 785 RNA chains solved experimentally.
14 methods * 785 seqs of RNA chains = 10990 != 8005
23. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
8005 secondary structure predictions have been obtained
for 785 RNA chains solved experimentally.
14 methods * 785 seqs of RNA chains = 10990 != 8005
The reason for this is that various methods predicting
RNA secondary structure have different length limits of
input RNA sequences
(e.g. McQFold: 500nt, Sfold: 6000nt).
24. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
How to compare reference and predicted RNA secondary
structures in order to benchmark performance of
individual methods?
25. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
http://comparna.amu.edu.pl/
The CompaRNA server http://iimcb.genesilico.pl/comparna/
How to compare reference and predicted RNA secondary
structures in order to benchmark performance of
individual methods?
Matthews correlation coefficient
26. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Outline of the presentation:
1) What is CompaRNA?
2) CompaRNA features
3) Future perspectives
4) Acknowledgements
27. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
CompaRNA features
DEMO
28. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Outline of the presentation:
1) What is CompaRNA?
2) CompaRNA features
3) Future perspectives
4) Acknowledgements
29. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
What do I want to do next?
- test methods predicting protein-RNA interactions
- create meta-methods predicting RNA secondary
structure & protein-RNA interactions based on individual
methods
- defend my PhD thesis
30. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Outline of the presentation:
1) Introduction to the prediction of RNA structure
and protein–RNA interactions
2) The CompaRNA server – present & past
3) Future perspectives
4) Acknowledgements
31. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Acknowledgements
Janusz Kristian Łukasz
Ewa Kasia Kaja Jurek Tomek
32. CompaRNA: a server for continuous benchmarking of RNA structure prediction methods
Thx for your attention
Questions !