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Compare and Contrast:
Lymphoma and Leukemia
Leukemia and lymphoma are heterogeneous disorders with various clinical courses.
Both disorders are biologically indistinguishable. Lymphoma or its clinical term Small
Lymphocytic Lymphoma is a term used for initial presentation in tissue, and where
leukemic phases of bone marrow or peripheral blood are absent in cases (Cecilia et al.,
2011). Lymphoma starts in the lymphoid tissue while leukemia starts in the bone
marrow, where it spreads to the blood (Gisselbrecht, Martis & Mounier, 2011).
Leukemia can then spread from the blood to body parts. Affected parts include the liver,
spleen, lymph nodes, among others. Leukemia mostly affects children, but can also
affect adults (Arden-Close, Pacey & Eiser, 2010). The similarity between lymphoma and
leukemia is that, at advanced stages, both affect the lymphatic system. The difference
between the diseases is seen in their classification, symptoms and biological
presentation. Leukemia can be conceptualized at onset and by the cell involved. The
onset of leukemia can be rapid and indolent (Cecilia et al., 2011). The types of cells
involved are myelogenous (which are monocytic and myeloid) and lymphoid. Therefore,
the basic classification for leukemia includes chronic lymphocytic leukemia, acute
lymphocytic leukemia, chronic myelogenous leukemia, and acute myelogenous
leukemia. Classification of leukemia is increasingly becoming difficult as more tests are
available to test the specific enzymatic, morphologic, genetic, and immunologic aspects
of the malignant cells. However, for lymphoma (non-Hodgkin’s lymphoma), its
classification is complicated. This is because it has two patterns of growth, diffuse and
nodular, where there are two cell sizes, large and small, and two nuclear features, non-
cleaved and cleaved (Cecilia et al., 2011). These form the basis of the classification of
these diseases. For Non-Hodgkin’s lymphoma, nodular occurs in older persons and is
disseminated as diagnosis and has a better prognosis that the diffuse lymphoma
(Gisselbrecht, Martis & Mounier, 2011). Hodgkin’s Lymphoma, has sevaral…
More on assignmentlab.com/ln-slideshare

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Compare and contrast lymphoma and leukemia - sample paper - essay

  • 2. Leukemia and lymphoma are heterogeneous disorders with various clinical courses. Both disorders are biologically indistinguishable. Lymphoma or its clinical term Small Lymphocytic Lymphoma is a term used for initial presentation in tissue, and where leukemic phases of bone marrow or peripheral blood are absent in cases (Cecilia et al., 2011). Lymphoma starts in the lymphoid tissue while leukemia starts in the bone marrow, where it spreads to the blood (Gisselbrecht, Martis & Mounier, 2011). Leukemia can then spread from the blood to body parts. Affected parts include the liver, spleen, lymph nodes, among others. Leukemia mostly affects children, but can also affect adults (Arden-Close, Pacey & Eiser, 2010). The similarity between lymphoma and leukemia is that, at advanced stages, both affect the lymphatic system. The difference between the diseases is seen in their classification, symptoms and biological presentation. Leukemia can be conceptualized at onset and by the cell involved. The onset of leukemia can be rapid and indolent (Cecilia et al., 2011). The types of cells involved are myelogenous (which are monocytic and myeloid) and lymphoid. Therefore, the basic classification for leukemia includes chronic lymphocytic leukemia, acute lymphocytic leukemia, chronic myelogenous leukemia, and acute myelogenous leukemia. Classification of leukemia is increasingly becoming difficult as more tests are available to test the specific enzymatic, morphologic, genetic, and immunologic aspects of the malignant cells. However, for lymphoma (non-Hodgkin’s lymphoma), its
  • 3. classification is complicated. This is because it has two patterns of growth, diffuse and nodular, where there are two cell sizes, large and small, and two nuclear features, non- cleaved and cleaved (Cecilia et al., 2011). These form the basis of the classification of these diseases. For Non-Hodgkin’s lymphoma, nodular occurs in older persons and is disseminated as diagnosis and has a better prognosis that the diffuse lymphoma (Gisselbrecht, Martis & Mounier, 2011). Hodgkin’s Lymphoma, has sevaral… More on assignmentlab.com/ln-slideshare