Introduction: Membranoproliferative glomerulonephritis has been reported to occur in association with non-Hodgkin’s lymphoma but there is few information about glomerulonephritis response to the treatment of non-Hodgkin’s lymphoma.Case Presentation: A 67 years-old caucasian female admitted to outpatient clinic with peripheral
edema complaint. She had mild proteinuria and microhematuria on admission and tuberculosis, nonHodgkin
lymphoma (cured), diabetes mellitus and hypertension history. Her renal biopsy resulted as membranoproliferative glomerulonephritis and after investigations she got recurrent non-Hodgkin lymphoma diagnosis. After successful treatment of her lymphoma her nephrotic syndrome clinic regressed
The common facts you should know about mesotheliomawordchapter
Several insinuations have floated round about mesothelioma that some people now cannot differentiate the facts from the mere gossips. Once, it was rumored that mesothelioma was communicable i.e. could be transferred from one person to another through direct contact. There are other true sides to the story which is often neglected. Some of those very important facts about mesothelioma are as follows;
THE MAIN CAUSE AND PREVENTION OF MULTIPLE SCLEROSIS AND ITS RELATION TO CANCERbanafsheh61
This document discusses the potential causes of multiple sclerosis (MS) and its relationship to cancer. It introduces the Evolutionary Metabolic Hypothesis of MS, which proposes that MS is caused by an increase in reactive oxygen species and reactive nitrogen species inside cells. This oxidative stress damages mitochondria and leads to inflammation and demyelination in the brain and spinal cord. The document reviews several studies that link mitochondrial dysfunction and oxidative damage to MS. It also discusses how cancer cells revert to an ancient fermentation process instead of using mitochondria, in order to avoid apoptosis. Therefore, both MS and cancer may be caused by mitochondrial damage and the resulting oxidative stress.
When Two Diseases Cross their Paths: The Diagnostic Challenge of Rheumatoid A...Crimson-Arthritis
When Two Diseases Cross their Paths: The Diagnostic Challenge of Rheumatoid Arthritis in Sickle Cell Disease Patients by Isabel M McFarlane in Researches in Arthritis & Bone Study
Myelophthisic anemia is a severe form of anemia caused by the displacement of bone marrow tissue into the bloodstream by conditions like fibrosis, tumors, or granulomas that affect the bone marrow. It is commonly seen in people with chronic myeloproliferative disorders or cancers that have spread to the bone marrow. A diagnosis can be made through blood tests showing abnormal red blood cells and immature blood cells in the blood, and confirmed by bone marrow biopsy demonstrating replacement of normal bone marrow tissue. Treatment focuses on treating the underlying cause through therapies for cancers, fibrosis, or other conditions occupying the bone marrow space.
Lung cancer results from abnormal cell growth and division that causes tumors. It tends to spread early, making it life-threatening. Symptoms vary depending on location and spread but include cough, shortness of breath, and coughing up blood. Treatment depends on cancer type, location, health, and spread and may include surgery, chemotherapy, radiation, or targeted drug therapy. Scientists recently discovered lung stem cells that could be precursors to lung cancer.
Introduction: Membranoproliferative glomerulonephritis has been reported to occur in association with non-Hodgkin’s lymphoma but there is few information about glomerulonephritis response to the treatment of non-Hodgkin’s lymphoma.Case Presentation: A 67 years-old caucasian female admitted to outpatient clinic with peripheral
edema complaint. She had mild proteinuria and microhematuria on admission and tuberculosis, nonHodgkin
lymphoma (cured), diabetes mellitus and hypertension history. Her renal biopsy resulted as membranoproliferative glomerulonephritis and after investigations she got recurrent non-Hodgkin lymphoma diagnosis. After successful treatment of her lymphoma her nephrotic syndrome clinic regressed
The common facts you should know about mesotheliomawordchapter
Several insinuations have floated round about mesothelioma that some people now cannot differentiate the facts from the mere gossips. Once, it was rumored that mesothelioma was communicable i.e. could be transferred from one person to another through direct contact. There are other true sides to the story which is often neglected. Some of those very important facts about mesothelioma are as follows;
THE MAIN CAUSE AND PREVENTION OF MULTIPLE SCLEROSIS AND ITS RELATION TO CANCERbanafsheh61
This document discusses the potential causes of multiple sclerosis (MS) and its relationship to cancer. It introduces the Evolutionary Metabolic Hypothesis of MS, which proposes that MS is caused by an increase in reactive oxygen species and reactive nitrogen species inside cells. This oxidative stress damages mitochondria and leads to inflammation and demyelination in the brain and spinal cord. The document reviews several studies that link mitochondrial dysfunction and oxidative damage to MS. It also discusses how cancer cells revert to an ancient fermentation process instead of using mitochondria, in order to avoid apoptosis. Therefore, both MS and cancer may be caused by mitochondrial damage and the resulting oxidative stress.
When Two Diseases Cross their Paths: The Diagnostic Challenge of Rheumatoid A...Crimson-Arthritis
When Two Diseases Cross their Paths: The Diagnostic Challenge of Rheumatoid Arthritis in Sickle Cell Disease Patients by Isabel M McFarlane in Researches in Arthritis & Bone Study
Myelophthisic anemia is a severe form of anemia caused by the displacement of bone marrow tissue into the bloodstream by conditions like fibrosis, tumors, or granulomas that affect the bone marrow. It is commonly seen in people with chronic myeloproliferative disorders or cancers that have spread to the bone marrow. A diagnosis can be made through blood tests showing abnormal red blood cells and immature blood cells in the blood, and confirmed by bone marrow biopsy demonstrating replacement of normal bone marrow tissue. Treatment focuses on treating the underlying cause through therapies for cancers, fibrosis, or other conditions occupying the bone marrow space.
Lung cancer results from abnormal cell growth and division that causes tumors. It tends to spread early, making it life-threatening. Symptoms vary depending on location and spread but include cough, shortness of breath, and coughing up blood. Treatment depends on cancer type, location, health, and spread and may include surgery, chemotherapy, radiation, or targeted drug therapy. Scientists recently discovered lung stem cells that could be precursors to lung cancer.
The document is a student paper about pediatric leukemia. It provides background on leukemia, describing what it is, signs and symptoms, types (acute vs. chronic; ALL, AML, CLL, CML), diagnosis process, and common treatments. It notes that leukemia is the most common cancer in children. While there is no cure, treatment success rates have improved significantly, with some forms having a 90% remission rate. Overall, the paper aims to educate about pediatric leukemia while also providing hope due to recent advancements.
This document is a paper about pediatric leukemia written by Savannah Brooks. It discusses what leukemia is, the types and symptoms of leukemia, how it is diagnosed and treated. It notes that leukemia is the most common cancer in children. While there is no cure, treatment success rates are high, especially when caught early, and many children are able to live long lives.
Leukemia is a cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells. There are several types classified by how quickly the disease develops (acute or chronic) and the affected blood cell type (lymphoid or myeloid). Common types include acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia. Treatment involves chemotherapy, radiation therapy, or stem cell transplantation and varies depending on the leukemia type and stage.
Jacinto Solivellas de Oleza supports non-profits like the Alexcar Leukaemia Foundation, which promotes research into cancers like leukemia and lymphoma. While both cancers originate in white blood cells, leukemia starts in the bone marrow and lymphoma starts in the lymphatic system. There are four main types of leukemia and two main types of lymphoma, and both are generally slow-growing but require prompt treatment based on cancer stage, often including chemotherapy and radiation.
Burkitt lymphoma is an aggressive B-cell lymphoma associated with translocations involving the c-MYC gene. There are three main types: endemic, sporadic, and HIV-associated. Endemic Burkitt lymphoma most commonly presents as an abdominal mass in children in Africa and is strongly associated with Epstein-Barr virus. The tumor cells are intermediate in size with vacuolated cytoplasm, giving the characteristic "starry sky" appearance. Burkitt lymphoma is highly aggressive but responsive to chemotherapy.
Burkitt lymphoma is an aggressive B-cell lymphoma associated with translocations involving the c-MYC gene. There are three main types: endemic, sporadic, and HIV-associated. Endemic Burkitt lymphoma most commonly presents as an abdominal mass in children in Africa and is strongly associated with Epstein-Barr virus. The tumor cells are intermediate in size with vacuolated cytoplasm, giving the characteristic "starry sky" appearance. Burkitt lymphoma is highly aggressive but responsive to chemotherapy.
Learning Objectives:
- Introduction
- Definition
- Classification
- Acute Leukaemia
- Predisposing Factors
- Acute Myeloid Leukaemia
- FAB & WHO Classification of AML
- Pathogenesis
- Clinical Features of AML
- Lab Diagnosis of AML
- Treatment of AML
Cancer is the name given to a collection of related diseases. In all types of cancer, some of the body's cells begin to divide without stopping and spread into surrounding tissue.
This document discusses different types of leukemias, including acute and chronic leukemias. It provides details on:
1. The bone marrow and its normal cellular composition. Bone marrow contains hematopoietic stem cells that form blood cells as well as stromal cells and bone-forming cells.
2. What leukemias are - disorders characterized by accumulation of malignant white blood cells in the bone marrow, sometimes spreading to blood and tissues. This displaces normal blood cell production.
3. The main types of leukemias - acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia. Key diagnostic criteria and cellular features of each type are outlined
Leukemia is a cancer of the blood and bone marrow that results in abnormal production of blood cells. There are four main types of leukemia - acute myelogenous leukemia, acute lymphocytic leukemia, chronic myelogenous leukemia, and chronic lymphocytic leukemia. Leukemia is caused by mutations in blood cell DNA that cause abnormal cell growth and loss of function. Diagnosis involves blood tests, biopsy, and imaging to examine blood cell counts and determine if cancer has spread. Treatment depends on the type of leukemia but may include chemotherapy, radiation therapy, stem cell transplantation, biological therapy, or targeted therapy.
The document discusses lymphoma, which is a cancer of the lymphatic system. It begins by describing the anatomy and function of the lymphatic system. It then defines lymphoma and discusses the two main types: Hodgkin lymphoma and non-Hodgkin lymphoma. Hodgkin lymphoma is characterized by the presence of Reed-Sternberg cells and has a good prognosis. Non-Hodgkin lymphoma is more common and diverse, with several subtypes that can vary in aggressiveness. The document outlines signs and symptoms, diagnostic tests, treatment options including chemotherapy and stem cell transplant, and the nursing management of patients with lymphoma.
What other blood cell related problems are often seen in patients wi.pdfoptokunal1
What other blood cell related problems are often seen in patients with chronic leukemia?
Citereferencesplease
Solution
The term leukemia is referred to neoplasm of hematopoietic tissue. Unlike the solid tumors the
leukemic cells diffuse into bone marrow and lymphoid tissues and spill over into blood stream to
spread to various organs of the body. The leukemic cells are either mature or extremely
primitive. Rich amounts of white blood cell counts in leukemia reveals the spread of tumors to
peripheral blood. However, the proliferation of white blood cells is mostly confined to bone
marrow and no significant increase in number of white blood cells in the blood stream can be
observed.
Leukemia is classified depending on the type of the cell and maturity of proliferating cell. Any
type of hematopoietic cell may produce leukemia but most common types are granulocytic,
monocytic and lymphocytic. The leukemia developing from stem cells produce the leukocytes
containing specific granules such as neutrophils, eosinophils and basophils. This type of
leukemia is called granulocytic leukemia. Monocytic leukemia is developed from the precursor
cells of monocytes. Lymphocytic leukemia is produced by lymphoid precursor cells.
When the leukemic cells are most primitive forms the neoplasm is called acute leukemia. The
leukemia with mature cells is called chronic leukemia. Chronic granulocyte leukemia is caused
by circulating matured granulocytes and neutrophils along with few primitive cells. Chronic
lymphocytic leukemia is caused by circulating mature lymphocytes.
The clinical features of leukemia are either caused by impairment of function of bone marrow or
caused by infiltration of leukemic cells into viscera. The overgrowth of leukemic cells in bone
marrow crowds out the normal cells leading to anemia because of inadequate production of red
blood cells. Bleeding is caused by thrombocytopenia and infection resulting from insufficient
numbers of white blood cells to provide protection by immune defense mechanism against
pathogens.
Leukemic cells spreading to other tissues may invade into spleen, liver, lymph nodes and other
tissues. The chronic leukemia proceeds at a slow rate and can be controlled by treatment over
long periods of time. Therefore, the patient may survive for several years. In an acute leukemia
the disease is rapidly progressive and leukemic cells infiltrate bone marrow and viscera with
conspicuous appearance.
1.American Cancer Society. Cancer Facts and Figures 2016. Atlanta, Ga: American Cancer
Society; 2016.
2. Byrd JC, Brown JR, O\'Brien S, et al. Ibrutinib versus ofatumumab in previously treated
chronic lymphoid leukemia. N Engl J Med. 2014 Jul 17;371(3):213-23. Epub 2014 May 31.
3. Byrd JC, Furman RR, Coutre SE, et al. Targeting BTK with ibrutinib in relapsed chronic
lymphocytic leukemia. N Engl J Med. 2013 Jul 4;369(1):32-42. Epub 2013 Jun 19.
4. Byrd JC, Flynn JM. Chronic lymphocytic leukemia. In: Niederhuber JE,Armitage JO,
Doroshow .
1. The document discusses the management of various types of leukemia including acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute myelogenous leukemia, and chronic myelogenous leukemia.
2. For acute lymphoblastic leukemia, treatment involves induction chemotherapy followed by consolidation therapy and maintenance treatments, sometimes including bone marrow transplantation.
3. Chronic lymphocytic leukemia treatment focuses on suppressing the disease for many years using chemotherapy with drugs like chlorambucil or cyclophosphamide along with corticosteroids.
4. Acute myelogenous leukemia treatment relies on combination chemotherapy during induction followed by additional chemotherapy phases.
5. Chronic myelogenous leukemia's standard treatment is imatinib therapy, and bone marrow transplantation
The document provides detailed information about acute myeloblastic leukemia (AML), including its definition, classification, symptoms, incidence, characteristics, and morphological subtypes. AML is a cancer of the blood and bone marrow characterized by rapid proliferation of immature blast cells. It is the most common type of acute leukemia in adults. The document discusses the French-American-British classification system and the World Health Organization classification system for AML and its various subtypes.
This document discusses lymphoma and its classification. It notes that lymphoma arises from lymphoid tissue and is the most common hematologic malignancy in developed countries. There are two main types, Hodgkin's and non-Hodgkin's lymphoma, with non-Hodgkin's lymphoma accounting for about 85% of cases. The two most common forms of non-Hodgkin's lymphoma are follicular lymphoma and diffuse large B-cell lymphoma. Classification of lymphoma has evolved based on immunophenotypic and genetic features. Many lymphomas express the antigen CD20, which has made it a target for developing monoclonal antibody therapies.
This document provides an introduction to lymphoma and radioimmunotherapy. It discusses that lymphoma originates from lymphoid tissue and is the most common hematologic malignancy. It describes the classification of lymphomas and focuses on two common types - follicular lymphoma and diffuse large B-cell lymphoma. It then introduces radioimmunotherapy as a targeted treatment approach using radiolabeled monoclonal antibodies, with a focus on the anti-CD20 antibody rituximab which is commonly used to treat CD20-positive lymphomas.
Leukemia is a type of blood cancer that develops when blood cells in the bone marrow grow out of control. The main types of leukemia are acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, and chronic lymphocytic leukemia. Leukemia can cause symptoms like fevers, infections, weakness, and bone or joint pain. While the exact causes are unknown, risk factors include radiation, viruses, chemicals, and genetic predisposition. Treatment involves chemotherapy administered through various methods, and recovery depends on the type and stage of leukemia.
Acute lymphocytic leukemia (ALL) is a cancer of the lymphoid cells in the bone marrow. Early symptoms include fever, fatigue, and enlarged lymph nodes. Diagnostic tests include blood tests, bone marrow biopsies, imaging scans, and spinal fluid tests to determine the extent of the cancer's spread. Treatment involves induction therapy to eliminate leukemia cells, consolidation therapy to destroy remaining cells, and maintenance therapy to prevent regrowth of the cancer.
Leukemia is a type of cancer that affects the blood and bone marrow. It results from abnormal proliferation of white blood cells. There are four main types of leukemia - acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, and chronic myelogenous leukemia. Leukemia is treated through chemotherapy, targeted therapy, radiation therapy or stem cell transplant depending on the type and stage of leukemia. Nursing care focuses on managing side effects of treatment, preventing infections, maintaining nutrition, providing education and supporting the psychological needs of the patient.
Gene therapy biology - sample paper - essayAssignment Lab
Gene therapy can treat genetic disorders by replacing a mutated gene that causes disease with a healthy copy of the gene. Viruses are often used as vehicles to deliver replacement genes into cells, but they can cause immune reactions. Liposomes are now seen as a better alternative as they can carry genes into cells without immune responses. Gene therapy aims to cure monogenic recessive disorders by adding a missing healthy gene, while dominant disorders may be treated through RNA interference to silence mutated genes.
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Similar to Compare and contrast lymphoma and leukemia - sample paper - essay
The document is a student paper about pediatric leukemia. It provides background on leukemia, describing what it is, signs and symptoms, types (acute vs. chronic; ALL, AML, CLL, CML), diagnosis process, and common treatments. It notes that leukemia is the most common cancer in children. While there is no cure, treatment success rates have improved significantly, with some forms having a 90% remission rate. Overall, the paper aims to educate about pediatric leukemia while also providing hope due to recent advancements.
This document is a paper about pediatric leukemia written by Savannah Brooks. It discusses what leukemia is, the types and symptoms of leukemia, how it is diagnosed and treated. It notes that leukemia is the most common cancer in children. While there is no cure, treatment success rates are high, especially when caught early, and many children are able to live long lives.
Leukemia is a cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells. There are several types classified by how quickly the disease develops (acute or chronic) and the affected blood cell type (lymphoid or myeloid). Common types include acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia. Treatment involves chemotherapy, radiation therapy, or stem cell transplantation and varies depending on the leukemia type and stage.
Jacinto Solivellas de Oleza supports non-profits like the Alexcar Leukaemia Foundation, which promotes research into cancers like leukemia and lymphoma. While both cancers originate in white blood cells, leukemia starts in the bone marrow and lymphoma starts in the lymphatic system. There are four main types of leukemia and two main types of lymphoma, and both are generally slow-growing but require prompt treatment based on cancer stage, often including chemotherapy and radiation.
Burkitt lymphoma is an aggressive B-cell lymphoma associated with translocations involving the c-MYC gene. There are three main types: endemic, sporadic, and HIV-associated. Endemic Burkitt lymphoma most commonly presents as an abdominal mass in children in Africa and is strongly associated with Epstein-Barr virus. The tumor cells are intermediate in size with vacuolated cytoplasm, giving the characteristic "starry sky" appearance. Burkitt lymphoma is highly aggressive but responsive to chemotherapy.
Burkitt lymphoma is an aggressive B-cell lymphoma associated with translocations involving the c-MYC gene. There are three main types: endemic, sporadic, and HIV-associated. Endemic Burkitt lymphoma most commonly presents as an abdominal mass in children in Africa and is strongly associated with Epstein-Barr virus. The tumor cells are intermediate in size with vacuolated cytoplasm, giving the characteristic "starry sky" appearance. Burkitt lymphoma is highly aggressive but responsive to chemotherapy.
Learning Objectives:
- Introduction
- Definition
- Classification
- Acute Leukaemia
- Predisposing Factors
- Acute Myeloid Leukaemia
- FAB & WHO Classification of AML
- Pathogenesis
- Clinical Features of AML
- Lab Diagnosis of AML
- Treatment of AML
Cancer is the name given to a collection of related diseases. In all types of cancer, some of the body's cells begin to divide without stopping and spread into surrounding tissue.
This document discusses different types of leukemias, including acute and chronic leukemias. It provides details on:
1. The bone marrow and its normal cellular composition. Bone marrow contains hematopoietic stem cells that form blood cells as well as stromal cells and bone-forming cells.
2. What leukemias are - disorders characterized by accumulation of malignant white blood cells in the bone marrow, sometimes spreading to blood and tissues. This displaces normal blood cell production.
3. The main types of leukemias - acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia. Key diagnostic criteria and cellular features of each type are outlined
Leukemia is a cancer of the blood and bone marrow that results in abnormal production of blood cells. There are four main types of leukemia - acute myelogenous leukemia, acute lymphocytic leukemia, chronic myelogenous leukemia, and chronic lymphocytic leukemia. Leukemia is caused by mutations in blood cell DNA that cause abnormal cell growth and loss of function. Diagnosis involves blood tests, biopsy, and imaging to examine blood cell counts and determine if cancer has spread. Treatment depends on the type of leukemia but may include chemotherapy, radiation therapy, stem cell transplantation, biological therapy, or targeted therapy.
The document discusses lymphoma, which is a cancer of the lymphatic system. It begins by describing the anatomy and function of the lymphatic system. It then defines lymphoma and discusses the two main types: Hodgkin lymphoma and non-Hodgkin lymphoma. Hodgkin lymphoma is characterized by the presence of Reed-Sternberg cells and has a good prognosis. Non-Hodgkin lymphoma is more common and diverse, with several subtypes that can vary in aggressiveness. The document outlines signs and symptoms, diagnostic tests, treatment options including chemotherapy and stem cell transplant, and the nursing management of patients with lymphoma.
What other blood cell related problems are often seen in patients wi.pdfoptokunal1
What other blood cell related problems are often seen in patients with chronic leukemia?
Citereferencesplease
Solution
The term leukemia is referred to neoplasm of hematopoietic tissue. Unlike the solid tumors the
leukemic cells diffuse into bone marrow and lymphoid tissues and spill over into blood stream to
spread to various organs of the body. The leukemic cells are either mature or extremely
primitive. Rich amounts of white blood cell counts in leukemia reveals the spread of tumors to
peripheral blood. However, the proliferation of white blood cells is mostly confined to bone
marrow and no significant increase in number of white blood cells in the blood stream can be
observed.
Leukemia is classified depending on the type of the cell and maturity of proliferating cell. Any
type of hematopoietic cell may produce leukemia but most common types are granulocytic,
monocytic and lymphocytic. The leukemia developing from stem cells produce the leukocytes
containing specific granules such as neutrophils, eosinophils and basophils. This type of
leukemia is called granulocytic leukemia. Monocytic leukemia is developed from the precursor
cells of monocytes. Lymphocytic leukemia is produced by lymphoid precursor cells.
When the leukemic cells are most primitive forms the neoplasm is called acute leukemia. The
leukemia with mature cells is called chronic leukemia. Chronic granulocyte leukemia is caused
by circulating matured granulocytes and neutrophils along with few primitive cells. Chronic
lymphocytic leukemia is caused by circulating mature lymphocytes.
The clinical features of leukemia are either caused by impairment of function of bone marrow or
caused by infiltration of leukemic cells into viscera. The overgrowth of leukemic cells in bone
marrow crowds out the normal cells leading to anemia because of inadequate production of red
blood cells. Bleeding is caused by thrombocytopenia and infection resulting from insufficient
numbers of white blood cells to provide protection by immune defense mechanism against
pathogens.
Leukemic cells spreading to other tissues may invade into spleen, liver, lymph nodes and other
tissues. The chronic leukemia proceeds at a slow rate and can be controlled by treatment over
long periods of time. Therefore, the patient may survive for several years. In an acute leukemia
the disease is rapidly progressive and leukemic cells infiltrate bone marrow and viscera with
conspicuous appearance.
1.American Cancer Society. Cancer Facts and Figures 2016. Atlanta, Ga: American Cancer
Society; 2016.
2. Byrd JC, Brown JR, O\'Brien S, et al. Ibrutinib versus ofatumumab in previously treated
chronic lymphoid leukemia. N Engl J Med. 2014 Jul 17;371(3):213-23. Epub 2014 May 31.
3. Byrd JC, Furman RR, Coutre SE, et al. Targeting BTK with ibrutinib in relapsed chronic
lymphocytic leukemia. N Engl J Med. 2013 Jul 4;369(1):32-42. Epub 2013 Jun 19.
4. Byrd JC, Flynn JM. Chronic lymphocytic leukemia. In: Niederhuber JE,Armitage JO,
Doroshow .
1. The document discusses the management of various types of leukemia including acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute myelogenous leukemia, and chronic myelogenous leukemia.
2. For acute lymphoblastic leukemia, treatment involves induction chemotherapy followed by consolidation therapy and maintenance treatments, sometimes including bone marrow transplantation.
3. Chronic lymphocytic leukemia treatment focuses on suppressing the disease for many years using chemotherapy with drugs like chlorambucil or cyclophosphamide along with corticosteroids.
4. Acute myelogenous leukemia treatment relies on combination chemotherapy during induction followed by additional chemotherapy phases.
5. Chronic myelogenous leukemia's standard treatment is imatinib therapy, and bone marrow transplantation
The document provides detailed information about acute myeloblastic leukemia (AML), including its definition, classification, symptoms, incidence, characteristics, and morphological subtypes. AML is a cancer of the blood and bone marrow characterized by rapid proliferation of immature blast cells. It is the most common type of acute leukemia in adults. The document discusses the French-American-British classification system and the World Health Organization classification system for AML and its various subtypes.
This document discusses lymphoma and its classification. It notes that lymphoma arises from lymphoid tissue and is the most common hematologic malignancy in developed countries. There are two main types, Hodgkin's and non-Hodgkin's lymphoma, with non-Hodgkin's lymphoma accounting for about 85% of cases. The two most common forms of non-Hodgkin's lymphoma are follicular lymphoma and diffuse large B-cell lymphoma. Classification of lymphoma has evolved based on immunophenotypic and genetic features. Many lymphomas express the antigen CD20, which has made it a target for developing monoclonal antibody therapies.
This document provides an introduction to lymphoma and radioimmunotherapy. It discusses that lymphoma originates from lymphoid tissue and is the most common hematologic malignancy. It describes the classification of lymphomas and focuses on two common types - follicular lymphoma and diffuse large B-cell lymphoma. It then introduces radioimmunotherapy as a targeted treatment approach using radiolabeled monoclonal antibodies, with a focus on the anti-CD20 antibody rituximab which is commonly used to treat CD20-positive lymphomas.
Leukemia is a type of blood cancer that develops when blood cells in the bone marrow grow out of control. The main types of leukemia are acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, and chronic lymphocytic leukemia. Leukemia can cause symptoms like fevers, infections, weakness, and bone or joint pain. While the exact causes are unknown, risk factors include radiation, viruses, chemicals, and genetic predisposition. Treatment involves chemotherapy administered through various methods, and recovery depends on the type and stage of leukemia.
Acute lymphocytic leukemia (ALL) is a cancer of the lymphoid cells in the bone marrow. Early symptoms include fever, fatigue, and enlarged lymph nodes. Diagnostic tests include blood tests, bone marrow biopsies, imaging scans, and spinal fluid tests to determine the extent of the cancer's spread. Treatment involves induction therapy to eliminate leukemia cells, consolidation therapy to destroy remaining cells, and maintenance therapy to prevent regrowth of the cancer.
Leukemia is a type of cancer that affects the blood and bone marrow. It results from abnormal proliferation of white blood cells. There are four main types of leukemia - acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, and chronic myelogenous leukemia. Leukemia is treated through chemotherapy, targeted therapy, radiation therapy or stem cell transplant depending on the type and stage of leukemia. Nursing care focuses on managing side effects of treatment, preventing infections, maintaining nutrition, providing education and supporting the psychological needs of the patient.
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Gene therapy biology - sample paper - essayAssignment Lab
Gene therapy can treat genetic disorders by replacing a mutated gene that causes disease with a healthy copy of the gene. Viruses are often used as vehicles to deliver replacement genes into cells, but they can cause immune reactions. Liposomes are now seen as a better alternative as they can carry genes into cells without immune responses. Gene therapy aims to cure monogenic recessive disorders by adding a missing healthy gene, while dominant disorders may be treated through RNA interference to silence mutated genes.
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2. Leukemia and lymphoma are heterogeneous disorders with various clinical courses.
Both disorders are biologically indistinguishable. Lymphoma or its clinical term Small
Lymphocytic Lymphoma is a term used for initial presentation in tissue, and where
leukemic phases of bone marrow or peripheral blood are absent in cases (Cecilia et al.,
2011). Lymphoma starts in the lymphoid tissue while leukemia starts in the bone
marrow, where it spreads to the blood (Gisselbrecht, Martis & Mounier, 2011).
Leukemia can then spread from the blood to body parts. Affected parts include the liver,
spleen, lymph nodes, among others. Leukemia mostly affects children, but can also
affect adults (Arden-Close, Pacey & Eiser, 2010). The similarity between lymphoma and
leukemia is that, at advanced stages, both affect the lymphatic system. The difference
between the diseases is seen in their classification, symptoms and biological
presentation. Leukemia can be conceptualized at onset and by the cell involved. The
onset of leukemia can be rapid and indolent (Cecilia et al., 2011). The types of cells
involved are myelogenous (which are monocytic and myeloid) and lymphoid. Therefore,
the basic classification for leukemia includes chronic lymphocytic leukemia, acute
lymphocytic leukemia, chronic myelogenous leukemia, and acute myelogenous
leukemia. Classification of leukemia is increasingly becoming difficult as more tests are
available to test the specific enzymatic, morphologic, genetic, and immunologic aspects
of the malignant cells. However, for lymphoma (non-Hodgkin’s lymphoma), its
3. classification is complicated. This is because it has two patterns of growth, diffuse and
nodular, where there are two cell sizes, large and small, and two nuclear features, non-
cleaved and cleaved (Cecilia et al., 2011). These form the basis of the classification of
these diseases. For Non-Hodgkin’s lymphoma, nodular occurs in older persons and is
disseminated as diagnosis and has a better prognosis that the diffuse lymphoma
(Gisselbrecht, Martis & Mounier, 2011). Hodgkin’s Lymphoma, has sevaral…
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