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Fluid Management
in Resuscitation
Muhammad Tsaqolain Pai
16 May 2024
Bilik Seminar
Topics
• Introduction
• Indication
• Phases of Fluid Resuscitation
• Assessment of Hydration
• Types of Fluid in Resuscitation
Introduction
• Treat fluid as drug (know 4D)
• Need to know when to give
• Take account of patient’s condition
• Treatment should be individualized
• Risk and benefit of fluid to patient
4 D’s of Fluid
DE-ESCALATION
DRUG DOSAGE
DURATION
Indication For Intravenous Fluid
1) Resuscitation : To correct an intravascular
volume deficit
2) Maintenance: to cover the patient’s daily basal
requirements of water, glucose and electrolytes.
3) Replacement Fluid: to correct fluid deficits that
cannot be compensated by oral intake
4) Nutrition Fluid
Too Low vs Too Much
Too low
(Restrictive)
- Cause
underhydration
- lead to
ischemia,
irreversible
injury, AKI
Too Much
- Cause
Overhydration
- Leads to edema,
hypoxia, overload,
fluid creep ,
irreversible injuries
Phases of Fluid Therapy (ROSE)
R.O.S.E Concept of Fluid Therapy
VOLUME STATUS
Resuscitation Optimisation Stabilisation Evacuation
Duration Minutes Hours Days Days to Week
Status Severe shock Unstable Stable Recovering
Examples - Septic shock
- Hemorrhagic shock
- Major burn
- Intraop
- <15% Burn
- GI Losses
- Post op Enteral feed
Aim/Goal Patient Rescue Organ Rescue (maintenance) +
avoid fluid overload/creep
Organ support/ homeostasis Focus on organ recovery and
resolving of fluid overload
Fluid Balance POSITIVE NEUTRAL ZERO- NEGATIVE BALANCE NEGATIVE
Fluid Type Balanced Crystalloid
Blood Product
Fluid replacement Maintenance
Remarks 30cc/kg/1 H or 4cc/kg bolus
given over 5-10 mins
Late conservative fluid
management
- 2 consecutive negative fluid
balance in a week
How to Assess Hydration?
• Traditional (static) vs Advanced (dynamic)
Traditional
- Clinical assessment (skin, eye, tongue, fontanelle etc)
- BP, HR, CRT
- Urine output
- CVP, PAC
- PAOP, EDV, IVC diameter
• Advanced ( Goal Directed)
- More precise
- Evaluate cardiac output response to preload (fluid
responsiveness)
- Echocardiography
- Lactate : for hyperlactinemia, signs of hypoperfusion
Types of Fluid in Resuscitation
Types of Fluid
Crystalloid
• Non Balanced Crystalloid : Normal Saline
• Balanced Crystalloid : Hartmann, Ringer’s, Sterofundin
• Isotonic Sodium Bicarbonate 1.3%
• Isotonic Sodium Bicarbonate 4.2%
Colloid
• Gelatin
• Hydroxyethyl Starch (HES)
• Human Albumin
Crystalloid as 1st line of Fluid in Resuscitation
• Why?
- Low viscosity
- Venodilator
- Provides high flow rate
Explain what is hyperchloremic met acidosis and how it helps in lossess?
*MAKE30 : Major Adverse Kidney Events by 30 days
Hartmann
Ringer’s
Sterofundin
NAGMA VS HAGMA
Anion Gap = Na + K ]- [ Cl+HCO3 ]
Normal Range : 8-16mmol/L
HYPERCHLOREMIA
(Decreased HCO3 compensated by Chloride)
NORMOCHLOREMIA
( Increased organic acids )
Take Home Message
• Treat fluid as a drug ( 4D)
• Start resuscitation with crystalloid
• Use balanced crystalloid in anticipation of > 2L: septic shock, DKA,
dengue
• Isotonic NaHCO3 reduces mortality in NAGMA, AKI patients
• Human albumin reduces mortality in septic patients
• Avoid gelatin and HES in septic patients
• Adopt restrictive fluid strategy
• Administer fluid according to ROSE, different fluid balance at
different phase
Thank You

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CME FLUID RESUSCITATION MALAYSIA BY TSAQOLAIN RASIP.pptx

  • 1. Fluid Management in Resuscitation Muhammad Tsaqolain Pai 16 May 2024 Bilik Seminar
  • 2. Topics • Introduction • Indication • Phases of Fluid Resuscitation • Assessment of Hydration • Types of Fluid in Resuscitation
  • 3. Introduction • Treat fluid as drug (know 4D) • Need to know when to give • Take account of patient’s condition • Treatment should be individualized • Risk and benefit of fluid to patient
  • 4. 4 D’s of Fluid DE-ESCALATION DRUG DOSAGE DURATION
  • 5. Indication For Intravenous Fluid 1) Resuscitation : To correct an intravascular volume deficit 2) Maintenance: to cover the patient’s daily basal requirements of water, glucose and electrolytes. 3) Replacement Fluid: to correct fluid deficits that cannot be compensated by oral intake 4) Nutrition Fluid
  • 6. Too Low vs Too Much Too low (Restrictive) - Cause underhydration - lead to ischemia, irreversible injury, AKI Too Much - Cause Overhydration - Leads to edema, hypoxia, overload, fluid creep , irreversible injuries
  • 7. Phases of Fluid Therapy (ROSE)
  • 8. R.O.S.E Concept of Fluid Therapy VOLUME STATUS Resuscitation Optimisation Stabilisation Evacuation Duration Minutes Hours Days Days to Week Status Severe shock Unstable Stable Recovering Examples - Septic shock - Hemorrhagic shock - Major burn - Intraop - <15% Burn - GI Losses - Post op Enteral feed Aim/Goal Patient Rescue Organ Rescue (maintenance) + avoid fluid overload/creep Organ support/ homeostasis Focus on organ recovery and resolving of fluid overload Fluid Balance POSITIVE NEUTRAL ZERO- NEGATIVE BALANCE NEGATIVE Fluid Type Balanced Crystalloid Blood Product Fluid replacement Maintenance Remarks 30cc/kg/1 H or 4cc/kg bolus given over 5-10 mins Late conservative fluid management - 2 consecutive negative fluid balance in a week
  • 9. How to Assess Hydration? • Traditional (static) vs Advanced (dynamic) Traditional - Clinical assessment (skin, eye, tongue, fontanelle etc) - BP, HR, CRT - Urine output - CVP, PAC - PAOP, EDV, IVC diameter
  • 10. • Advanced ( Goal Directed) - More precise - Evaluate cardiac output response to preload (fluid responsiveness) - Echocardiography - Lactate : for hyperlactinemia, signs of hypoperfusion
  • 11.
  • 12.
  • 13. Types of Fluid in Resuscitation
  • 14. Types of Fluid Crystalloid • Non Balanced Crystalloid : Normal Saline • Balanced Crystalloid : Hartmann, Ringer’s, Sterofundin • Isotonic Sodium Bicarbonate 1.3% • Isotonic Sodium Bicarbonate 4.2% Colloid • Gelatin • Hydroxyethyl Starch (HES) • Human Albumin
  • 15. Crystalloid as 1st line of Fluid in Resuscitation • Why? - Low viscosity - Venodilator - Provides high flow rate
  • 16.
  • 17. Explain what is hyperchloremic met acidosis and how it helps in lossess?
  • 18.
  • 19. *MAKE30 : Major Adverse Kidney Events by 30 days
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 32. NAGMA VS HAGMA Anion Gap = Na + K ]- [ Cl+HCO3 ] Normal Range : 8-16mmol/L HYPERCHLOREMIA (Decreased HCO3 compensated by Chloride) NORMOCHLOREMIA ( Increased organic acids )
  • 33. Take Home Message • Treat fluid as a drug ( 4D) • Start resuscitation with crystalloid • Use balanced crystalloid in anticipation of > 2L: septic shock, DKA, dengue • Isotonic NaHCO3 reduces mortality in NAGMA, AKI patients • Human albumin reduces mortality in septic patients • Avoid gelatin and HES in septic patients • Adopt restrictive fluid strategy • Administer fluid according to ROSE, different fluid balance at different phase