Clinical Pharmacotherapy of Gout disease

1. Gout
Sreenu Thalla
Associate Professor
Department of Pharmacology

17. Treatment Goals
• Gout can be treated without complications.
• Therapeutic goals include
– terminating attacks
– providing control of pain and inflammation
– preventing future attacks
– preventing complications such as renal stones and destructive
arthropathy

23. Non- Pharmacologic Treatments
• Immobilization of Joint
• Ice Packs
• Abstinence of Alcohol
– Consumption can increase serum urate levels by increasing uric acid
production.
– When used in excess it can be converted to lactic acid which inhibits uric acid
excretion in the kidney
• Dietary modification
– Low carbohydrates
– Increase in protein and unsaturated fats
– Decrease in dietary purine-meat and seafood.
– Dairy and vegetables do not seem to affect uric acid
• Bing cherries and Vitamin C

28. Thank you