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Choosing the Right Treatment: Medications, Stenting, or Surgical Intervention Tony Nguyen Bio-Engineering
Removing wastes from the body Release of certain hormones Helps control blood pressure What does a kidney do?
The main artery to the kidney Carries oxygen and nutrients Renal Artery
Artery Blockage Pressure drop Kidney is fooled Induces the Renin-Angiotensin Mechanism Overall increase in blood pressure & volume  What happens in a stenosis?
Medications  ACE inhibitors, beta blockers, ARB inhibitors Blocks the renin-angiotensin mechanism Different Treatments
Stenting Improve blood flow Different Treatments
Surgical Intervention Associated risks Different Treatments
3 months: prescreening & b.p. tests 3 months: diagnosis & b.p. tests 1 year: medications & b.p. tests 1 year: stenting & b.p. tests 1 year: surgery & b.p. tests Experimental Design
Two kinds of patients >> 140/90 mmHg (Group I) ≈ 140/90 mmHg (Group II) Improvement Group I gets to140/90 mmHg Group II gets to 130/85 mmHg Everything else is a failure Threshold for Improvement
Stenting will be the most effective It should reduce medications Not as risky Not as time consuming Hypothesis
Reduce errors  Reduce unnecessary risks Reduce costs Reduce time Why is this important?
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Choosing The Right Diagnosis

  • 1. Choosing the Right Treatment: Medications, Stenting, or Surgical Intervention Tony Nguyen Bio-Engineering
  • 2. Removing wastes from the body Release of certain hormones Helps control blood pressure What does a kidney do?
  • 3. The main artery to the kidney Carries oxygen and nutrients Renal Artery
  • 4. Artery Blockage Pressure drop Kidney is fooled Induces the Renin-Angiotensin Mechanism Overall increase in blood pressure & volume What happens in a stenosis?
  • 5. Medications ACE inhibitors, beta blockers, ARB inhibitors Blocks the renin-angiotensin mechanism Different Treatments
  • 6. Stenting Improve blood flow Different Treatments
  • 7. Surgical Intervention Associated risks Different Treatments
  • 8. 3 months: prescreening & b.p. tests 3 months: diagnosis & b.p. tests 1 year: medications & b.p. tests 1 year: stenting & b.p. tests 1 year: surgery & b.p. tests Experimental Design
  • 9. Two kinds of patients >> 140/90 mmHg (Group I) ≈ 140/90 mmHg (Group II) Improvement Group I gets to140/90 mmHg Group II gets to 130/85 mmHg Everything else is a failure Threshold for Improvement
  • 10. Stenting will be the most effective It should reduce medications Not as risky Not as time consuming Hypothesis
  • 11. Reduce errors Reduce unnecessary risks Reduce costs Reduce time Why is this important?