Chemometric techniques for quantitative analysis richard kramer

•

2 likes•2,223 views

The document discusses the benefits of exercise for mental health. It states that regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness.

Science

Chemometric techniques for quantitative analysis richard kramer

Recently uploaded

Below are the important points I note from the 2020 paper by Martin Grohe: - 1-WL distinguishes almost all graphs, in a probabilistic sense - Classical WL is two dimensional Weisfeiler-Leman - DeepWL is an unlimited version of WL graph that runs in polynomial time. - Knowledge graphs are essentially graphs with vertex/edge attributes ABSTRACT: Vector representations of graphs and relational structures, whether handcrafted feature vectors or learned representations, enable us to apply standard data analysis and machine learning techniques to the structures. A wide range of methods for generating such embeddings have been studied in the machine learning and knowledge representation literature. However, vector embeddings have received relatively little attention from a theoretical point of view. Starting with a survey of embedding techniques that have been used in practice, in this paper we propose two theoretical approaches that we see as central for understanding the foundations of vector embeddings. We draw connections between the various approaches and suggest directions for future research.

word2vec, node2vec, graph2vec, X2vec: Towards a Theory of Vector Embeddings o...

Subhajit Sahu

Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.

Richard's aventures in two entangled wonderlands

Richard Gill

erythropoiesis-I_mechanism& clinical significance.pptx

muralinath2

Anemia_ different types_causes_ conditions

muralinath2

insect taxonomy importance systematics and classification

anitaento25

Structures and textures of metamorphic rocks

kumarmathi863

Comparative structure of adrenal gland in vertebrates

sachin783648

Large scale production of streptomycin.pptx

Cherry

GLOBAL AND LOCAL SCENARIO OF FOOD AND NUTRITION.pptx

SultanMuhammadGhauri

GEOLOGICAL FIELD REPORT On Kaptai Rangamati Road-Cut Section.pdf

University of Barishal

Astronomy Update- Curiosity’s exploration of Mars _ Local Briefs _ leadertele...

NathanBaughman3

Slide 1: Title Slide Extrachromosomal Inheritance Slide 2: Introduction to Extrachromosomal Inheritance Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus. Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids. Slide 3: Mitochondrial Inheritance Mitochondria: Organelles responsible for energy production. Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria. Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring. Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy. Slide 4: Chloroplast Inheritance Chloroplasts: Organelles responsible for photosynthesis in plants. Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts. Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species. Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA. Slide 5: Plasmid Inheritance Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes. Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation. Significance: Important in biotechnology for gene cloning and genetic engineering. Slide 6: Mechanisms of Extrachromosomal Inheritance Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance. Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells. Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression. Slide 7: Examples of Extrachromosomal Inheritance Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells. Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration. Slide 8: Importance of Extrachromosomal Inheritance Evolution: Provides insight into the evolution of eukaryotic cells. Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases. Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification. Slide 9: Recent Research and Advances Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA. Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases. Slide 10: Conclusion Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology. Future Directions: Continued research and technological advancements hold promise for new treatments and applications. Slide 11: Questions and Discussion Invite Audience: Open the floor for any questions or further discussion on the topic.

extra-chromosomal-inheritance[1].pptx.pdfpdf

DiyaBiswas10

BLOOD AND BLOOD COMPONENT- introduction to blood physiology

NoelManyise1

Introduction: RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression. It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences. dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants. This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes. What are small ncRNAs? micro RNA (miRNA) short interfering RNA (siRNA) Properties of small non-coding RNA: Involved in silencing mRNA transcripts. Called “small” because they are usually only about 21-24 nucleotides long. Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered). Silence an mRNA by base pairing with some sequence on the mRNA. Discovery of siRNA? The first small RNA: In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the development of the worm C. elegans. Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14. Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions. Types of RNAi ( non coding RNA) MiRNA Length (23-25 nt) Trans acting Binds with target MRNA in mismatch Translation inhibition Si RNA Length 21 nt. Cis acting Bind with target Mrna in perfect complementary sequence Piwi-RNA Length ; 25 to 36 nt. Expressed in Germ Cells Regulates trnasposomes activity MECHANISM OF RNAI: First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces. Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands. The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it. THE RISC COMPLEX: RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA Unwinding of double stranded Si RNA by ATP independent Helicase Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA. DICER: endonuclease (RNase Family III) Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC) One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute ARGONAUTE PROTEIN : 1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA 2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity. MiRNA: The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .

RNA INTERFERENCE: UNRAVELING GENETIC SILENCING

AADYARAJPANDEY1

Mammalian Pineal Body Structure and Also Functions

YOGESH DOGRA

NuGOweek 2024 Ghent - programme - final version

pablovgd

Hemoglobin metabolism_pathophysiology.pptx

muralinath2

insect morphology and physiology of insect

anitaento25

We report on the discovery of Gliese 12 b, the nearest transiting temperate, Earth-sized planet found to date. Gliese 12 is a bright (V = 12.6 mag, K = 7.8 mag) metal-poor M4V star only 12.162 ± 0.005 pc away from the Solar system with one of the lowest stellar activity levels known for M-dwarfs. A planet candidate was detected by TESS based on only 3 transits in sectors 42, 43, and 57, with an ambiguity in the orbital period due to observational gaps. We performed follow-up transit observations with CHEOPS and ground-based photometry with MINERVA-Australis, SPECULOOS, and Purple Mountain Observatory, as well as further TESS observations in sector 70. We statistically validate Gliese 12 b as a planet with an orbital period of 12.76144 ± 0.00006 d and a radius of 1.0 ± 0.1 R⊕, resulting in an equilibrium temperature of ∼315 K. Gliese 12 b has excellent future prospects for precise mass measurement, which may inform how planetary internal structure is affected by the stellar compositional environment. Gliese 12 b also represents one of the best targets to study whether Earth-like planets orbiting cool stars can retain their atmospheres, a crucial step to advance our understanding of habitability on Earth and across the galaxy.

Gliese 12 b, a temperate Earth-sized planet at 12 parsecs discovered with TES...

Sérgio Sacani

Circulatory system_ Laplace law. Ohms law.reynaults law,baro-chemo-receptors-...

muralinath2

Recently uploaded (20)

word2vec, node2vec, graph2vec, X2vec: Towards a Theory of Vector Embeddings o...

Richard's aventures in two entangled wonderlands

erythropoiesis-I_mechanism& clinical significance.pptx

Anemia_ different types_causes_ conditions

insect taxonomy importance systematics and classification

Structures and textures of metamorphic rocks

Comparative structure of adrenal gland in vertebrates

Large scale production of streptomycin.pptx

GLOBAL AND LOCAL SCENARIO OF FOOD AND NUTRITION.pptx

GEOLOGICAL FIELD REPORT On Kaptai Rangamati Road-Cut Section.pdf

Astronomy Update- Curiosity’s exploration of Mars _ Local Briefs _ leadertele...

extra-chromosomal-inheritance[1].pptx.pdfpdf

BLOOD AND BLOOD COMPONENT- introduction to blood physiology

RNA INTERFERENCE: UNRAVELING GENETIC SILENCING

Mammalian Pineal Body Structure and Also Functions

NuGOweek 2024 Ghent - programme - final version

Hemoglobin metabolism_pathophysiology.pptx

insect morphology and physiology of insect

Gliese 12 b, a temperate Earth-sized planet at 12 parsecs discovered with TES...

Circulatory system_ Laplace law. Ohms law.reynaults law,baro-chemo-receptors-...

Featured

Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits. To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups. Technology For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did. While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis. Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad. Age and Gender When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same. Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers. Race Affects Attitudes As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).

How Race, Age and Gender Shape Attitudes Towards Mental Health

ThinkNow

AI Trends in Creative Operations 2024 by Artwork Flow.pdf

marketingartwork

Skeleton Culture Code

Skeleton Technologies

PEPSICO Presentation to CAGNY Conference Feb 2024

Neil Kimberley

Content Methodology: A Best Practices Report (Webinar)

contently

How to Prepare For a Successful Job Search for 2024

Albert Qian

A report by thenetworkone and Kurio. The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).

Social Media Marketing Trends 2024 // The Global Indie Insights

Kurio // The Social Media Age(ncy)

The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands. It’s important that you’re ready to implement new strategies in 2024. Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024. You’ll learn: - The latest trends in AI and automation, and what this means for an evolving paid search ecosystem. - New developments in privacy and data regulation. - Emerging ad formats that are expected to make an impact next year. Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape. If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.

Trends In Paid Search: Navigating The Digital Landscape In 2024

Search Engine Journal

From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world. With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively. The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage. Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience. See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers See the original article on Forbes here: http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b

5 Public speaking tips from TED - Visualized summary

SpeakerHub

Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world. Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance. For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age. Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.

ChatGPT and the Future of Work - Clark Boyd

Clark Boyd

Getting into the tech field. what next

Tessa Mero

Google's Just Not That Into You: Understanding Core Updates & Search Intent

Lily Ray

How to have difficult conversations

Rajiv Jayarajah, MAppComm, ACC

Introduction to Data Science

Christy Abraham Joy

Time Management & Productivity - Best Practices

Vit Horky

The six step guide to practical project management If you think managing projects is too difficult, think again. We’ve stripped back project management processes to the basics – to make it quicker and easier, without sacrificing the vital ingredients for success. “If you’re looking for some real-world guidance, then The Six Step Guide to Practical Project Management will help.” Dr Andrew Makar, Tactical Project Management

The six step guide to practical project management

MindGenius

Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...

RachelPearson36

During this webinar, Anand Bagmar demonstrates how AI tools such as ChatGPT can be applied to various stages of the software development life cycle (SDLC) using an eCommerce application case study. Find the on-demand recording and more info at https://applitools.info/b59 Key takeaways: • Learn how to use ChatGPT to add AI power to your testing and test automation • Understand the limitations of the technology and where human expertise is crucial • Gain insight into different AI-based tools • Adopt AI-based tools to stay relevant and optimize work for developers and testers * ChatGPT and OpenAI belong to OpenAI, L.L.C.

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

Applitools

12 Ways to Increase Your Influence at Work

GetSmarter

ChatGPT webinar slides

Alireza Esmikhani

Featured (20)

How Race, Age and Gender Shape Attitudes Towards Mental Health

AI Trends in Creative Operations 2024 by Artwork Flow.pdf

Skeleton Culture Code

PEPSICO Presentation to CAGNY Conference Feb 2024

Content Methodology: A Best Practices Report (Webinar)

How to Prepare For a Successful Job Search for 2024

Social Media Marketing Trends 2024 // The Global Indie Insights

Trends In Paid Search: Navigating The Digital Landscape In 2024

5 Public speaking tips from TED - Visualized summary

ChatGPT and the Future of Work - Clark Boyd

Getting into the tech field. what next

Google's Just Not That Into You: Understanding Core Updates & Search Intent

How to have difficult conversations

Introduction to Data Science

Time Management & Productivity - Best Practices

The six step guide to practical project management

Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

12 Ways to Increase Your Influence at Work

ChatGPT webinar slides

Chemometric techniques for quantitative analysis richard kramer

Recommended

Recommended

More Related Content

Recently uploaded

Recently uploaded (20)

Featured

Featured (20)