The CHA2DS2-VASc score was developed to improve on the CHADS2 score for assessing stroke risk in patients with atrial fibrillation. The CHA2DS2-VASc score assigns points for several additional risk factors compared to the CHADS2 score, including vascular disease, age 65-74, and female sex. A study of over 7,000 patients found the CHA2DS2-VASc score more accurately stratified patient stroke risk compared to the CHADS2 score, with adjusted stroke rates varying from 0% to 15.2% depending on the CHA2DS2-VASc score.

1. CHADS2 -> CHA2DS2VASc

2. CHADS2 -> CHA2DS2VASc
CHA2DS2-VASc Score
CHADS2 Risk Score Risk
CHF 1 CHF or LVEF < 1
40%
Hypertension 1 Hypertension 1
Age > 75 2
Age > 75 1 Diabetes 1
Stroke/TIA/ 2
Diabetes 1
Thromboembolism
Stroke or TIA 2 Vascular 1
Disease
Age 65 - 74 1
From ESC AF Guidelines
http://www.escardio.org/guidelines-surveys/esc- Female 1
guidelines/GuidelinesDocuments/guidelines-afib-FT.pdf

3. CHADS2 -> CHA2DS2VASc
CHA2DS2- Patients (n Adjusted
CHADS2 Patients Adjusted VASc = 7329) stroke
score (n = 1733) stroke rate score rate
%/year (%/year)
0 1 0
0 120 1.9
1 422 1.3
1 463 2.8 2 1230 2.2
2 523 4.0 3 1730 3.2
4 1718 4.0
3 337 5.9
5 1159 6.7
4 220 8.5 6 679 9.8
7 294 9.6
5 65 12.5
8 82 6.7
6 5 18.2 9 14 15.2
From ESC AF Guidelines: http://www.escardio.org/guidelines-surveys/esc-
guidelines/GuidelinesDocuments/guidelines-afib-FT.pdf