This chapter discusses how enterprise systems, supply chain management systems, and customer relationship management systems help businesses achieve operational excellence and customer intimacy. It provides an overview of these types of systems, including how they integrate across business functions and with external partners. Enterprise systems like ERP standardize business processes and share information company-wide. SCM systems coordinate planning, production, and logistics across the supply chain. CRM systems capture customer data to improve marketing, sales, and customer service. The chapter also explores challenges in implementing these systems and how they enable new services.