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Celulită
Celulitaeste omaladie ațesutului adipos.Ultimele cercetări făcute pe biopsiațesutului adiposau
relevatfaptul căeste o tulburare de tipregresiv.
Cauze
Sub influența diferiților factori alimentari sau hormonali, celulele grase sau adipocitele pot
acumula grăsimi care provin dintr-o alimentație necorespunzătoare. Adevărate rezerve de
grăsime, adipocitele pot crește depășind de circa 60 ori volumul lor normal, comprimând astfel
vasele sangvine, rezultând un drenaj încetinit și o oxigenare precară a epidermei. Celulita se
formează cu predilecție la nivelul coapselor, feselor și abdomenului, mai ales la femei si mult
mai rar la bărbați, datorită numărului mai mare de adipocite prezente la sexul feminin. [1] De
asemenea, pereții capilarelor devin permeabili la albumină din diferite cauze (citokinele- un
antigen, modificarea echilibrului acido-bazic al mediului intern etc). În mod normal aceștia sunt
impermeabili pentru albumine. Albumina, trecând în lichidul interstițial (lichidul extracelular-
LEC), creează o presiune oncotică mai mare decât cea normală în LEC. Această presiune tinde
să egalizeze presiunea oncotică din capilar, care are rolul de a absorbi apa în exces din LEC, în
partea venoasă a capilarului. Nemaiexistând o presiune suficientă de absorbție, apa rămâne în
LEC, generând microedeme. Aceste microedeme creează o presiune asupra celulei și capilarului
activând un sistem de apărare, hiperplazia și hipertrofia sistemului reticular. Succesiv, are loc
diferențierea fibrelor de colagen (întărirea cu colagen a fibrelor). Astfel ia naștere micronodulul,
o capsulă cu adipocite deteriorate de procesul regresiv abiotrofic, înconjurată de colagen, izolată
de țesutul adipos irigat. Procesul extinzându-se are loc o îmbinare a mai multor noduli, generând
macronodulul.
Evoluție
 Stadiul I - aparițiapermeabilității capilare și inundareațesutului adiposcufluide.Are loc
displaziași hipertrofiațesutului reticular.Se observădoarușoare variații învolumațesutului
adipos.
 Stadiul II - diferențiereafibrelorde colagen
 Stadiul III - formareamicronodulelor
 Stadiul IV -formareamacronodulelor

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Celulită

  • 1. Celulită Celulitaeste omaladie ațesutului adipos.Ultimele cercetări făcute pe biopsiațesutului adiposau relevatfaptul căeste o tulburare de tipregresiv. Cauze Sub influența diferiților factori alimentari sau hormonali, celulele grase sau adipocitele pot acumula grăsimi care provin dintr-o alimentație necorespunzătoare. Adevărate rezerve de grăsime, adipocitele pot crește depășind de circa 60 ori volumul lor normal, comprimând astfel vasele sangvine, rezultând un drenaj încetinit și o oxigenare precară a epidermei. Celulita se formează cu predilecție la nivelul coapselor, feselor și abdomenului, mai ales la femei si mult mai rar la bărbați, datorită numărului mai mare de adipocite prezente la sexul feminin. [1] De asemenea, pereții capilarelor devin permeabili la albumină din diferite cauze (citokinele- un antigen, modificarea echilibrului acido-bazic al mediului intern etc). În mod normal aceștia sunt impermeabili pentru albumine. Albumina, trecând în lichidul interstițial (lichidul extracelular- LEC), creează o presiune oncotică mai mare decât cea normală în LEC. Această presiune tinde să egalizeze presiunea oncotică din capilar, care are rolul de a absorbi apa în exces din LEC, în partea venoasă a capilarului. Nemaiexistând o presiune suficientă de absorbție, apa rămâne în LEC, generând microedeme. Aceste microedeme creează o presiune asupra celulei și capilarului activând un sistem de apărare, hiperplazia și hipertrofia sistemului reticular. Succesiv, are loc diferențierea fibrelor de colagen (întărirea cu colagen a fibrelor). Astfel ia naștere micronodulul, o capsulă cu adipocite deteriorate de procesul regresiv abiotrofic, înconjurată de colagen, izolată de țesutul adipos irigat. Procesul extinzându-se are loc o îmbinare a mai multor noduli, generând macronodulul. Evoluție  Stadiul I - aparițiapermeabilității capilare și inundareațesutului adiposcufluide.Are loc displaziași hipertrofiațesutului reticular.Se observădoarușoare variații învolumațesutului adipos.  Stadiul II - diferențiereafibrelorde colagen  Stadiul III - formareamicronodulelor  Stadiul IV -formareamacronodulelor