CVS launched the 'Be the First' campaign in 2016, committing $50 million over five years to reduce smoking among youth and promote a tobacco-free generation. The campaign targets young smokers, those at risk, and aims to educate them about smoking's dangers while doubling the number of smoke-free campuses. Key strengths include CVS's funding and reach, but barriers include rising vaping rates and limited in-store promotion of the initiative.