Catherine Harkins, a 23-year-old wife and mother from Ireland, had a recurring dream in 1857 of St. Vincent de Paul helping neglected children which led her to form the first Association of the Ladies of Charity in St. Louis, Missouri with 12 initial members to aid the poor. As the organization's first president, Catherine collaborated with Vincentian priests and Daughters of Charity on social outreach projects. She maintained her charitable work even after being widowed twice and raising three children, helping establish the Ladies of Charity across the United States.