The document outlines a process to accelerate achievement of Millennium Development Goals 4 and 5 relating to maternal and newborn health. It describes a conference called "Parliamentarians Take Action on Maternal and Newborn Health" that was convened to develop a template for in-country implementation of the goals. The conference used an innovative process called "meshworking" to develop pillars, conditions, and stories of success as a roadmap for countries. This template represents the first step in a three-step process to achieve large-scale change through collaboration within and between countries. The overall process combines leadership, facilitation, online collaboration and monitoring to improve synergy, speed and cost-effectiveness in reaching the development goals.