This document presents a case study of a 47-year-old male patient presenting with left knee pain and swelling for 2.5 months. After examination and investigations, he was diagnosed with osteoarthritis (sandhivata) of the left knee. In Ayurveda, osteoarthritis is viewed as a condition caused by vitiation of vata dosha, leading to destruction of cartilage and bone in the joint. The patient's treatment included purification therapies like herbal decoction enema and medicated oil enema, followed by pacifying therapies like application of herbal oils and pastes to the affected knee joint.