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A 17 year old M child taken to the
emergency department by his father
complained of sudden fall in floor , don’t
able to move leg properly ,slurring of
voice.
 He live in a hostal where he develop some kind of blisters in
face, trunk and had normal fever. For that he went to the Out
patient Department and doctor make diagnosis as chicken pox
and prescribed Antipyretic for fever and advised to take plenty
of fluid and take rest. He came back to the home
After 12 day in the evening he developed severe headaches for
that he take ibuprofen painkiller ,Next morning when he get up
not able speech properly and sudden fall down in floor and
bought to the hospital by father.
History of patient:-
Objective examination
Condition of patient is satisfactory and conscious ,
temperature is 37.4 , pleomorphic blister seen on face and
trunk area
Heart sound is clear and rhythmic.pulse rate 79b/min ,
blood pressure 122/80.lymph node are not enlarged.
Abdominal organ is normal in shape, no pain feel on
palpation
BMI-21kg/m2 .
CVS S1 S2 hear no murmur
Neurological status
More space between leg when walking (ataxia gait),
Inability to perform fast movement (adiadochokinesia) ,
Dysarthria ( inability to speak clearly),
Loss of coordination during walking.,
Normal eye movement
Muscle tone is normal,pharyngeal and gag reflex are normal,
patient swallowing food and water him own.
Pass-pointing positive (finger nose test )
Investigation
MRI shown mild hyper-density in cerebellum area.
CSF real time PCR FOR Adenovirus, enterovirus,
EBV, HHV7, HHV6, human parechovirus ,parvo
virus b19 , Cytomegalovirus,herpes simplex virus
1,2 is negative
VZV Is detected in csf
Investigati
on
Blood count
Hb 13.1
TLC 8480
PLT 4.87 lakh
N/L/M 74.6/56.5/6.5
CSF
examination
Gross Clear
Protein 560mg/dl
Glucose 57mg/dl
Cell 13 per mul
Chloride 117Meq/l
Diagnosis ??
VERECELLA ENCEPHALITIS FOLLOWED
BY ACUTE CEREBELLAR ATAXIA
Treatment
 Intravenous Normal saline
 Intravenous Acyclovir
Thank you!

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Case of varicella zoster virus encephalitis

  • 1. A 17 year old M child taken to the emergency department by his father complained of sudden fall in floor , don’t able to move leg properly ,slurring of voice.
  • 2.  He live in a hostal where he develop some kind of blisters in face, trunk and had normal fever. For that he went to the Out patient Department and doctor make diagnosis as chicken pox and prescribed Antipyretic for fever and advised to take plenty of fluid and take rest. He came back to the home After 12 day in the evening he developed severe headaches for that he take ibuprofen painkiller ,Next morning when he get up not able speech properly and sudden fall down in floor and bought to the hospital by father. History of patient:-
  • 3. Objective examination Condition of patient is satisfactory and conscious , temperature is 37.4 , pleomorphic blister seen on face and trunk area Heart sound is clear and rhythmic.pulse rate 79b/min , blood pressure 122/80.lymph node are not enlarged. Abdominal organ is normal in shape, no pain feel on palpation BMI-21kg/m2 . CVS S1 S2 hear no murmur
  • 4. Neurological status More space between leg when walking (ataxia gait), Inability to perform fast movement (adiadochokinesia) , Dysarthria ( inability to speak clearly), Loss of coordination during walking., Normal eye movement Muscle tone is normal,pharyngeal and gag reflex are normal, patient swallowing food and water him own. Pass-pointing positive (finger nose test )
  • 5. Investigation MRI shown mild hyper-density in cerebellum area. CSF real time PCR FOR Adenovirus, enterovirus, EBV, HHV7, HHV6, human parechovirus ,parvo virus b19 , Cytomegalovirus,herpes simplex virus 1,2 is negative VZV Is detected in csf
  • 6. Investigati on Blood count Hb 13.1 TLC 8480 PLT 4.87 lakh N/L/M 74.6/56.5/6.5
  • 7. CSF examination Gross Clear Protein 560mg/dl Glucose 57mg/dl Cell 13 per mul Chloride 117Meq/l
  • 9. VERECELLA ENCEPHALITIS FOLLOWED BY ACUTE CEREBELLAR ATAXIA
  • 10. Treatment  Intravenous Normal saline  Intravenous Acyclovir