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Cannassure Therapeutics Ltd
Investors Deck | February 2019
TASE:
© Cannassure Therapeutics Ltd
2
© Cannassure Therapeutics LtdWe do it right
This presentation has been prepared by the
Company and should not be considered as
a recommendation or recommendation for
the purchase or sale of securities and / or
investment in Cannassure Therapeutics
Ltd. This presentation is intended for the
purpose of providing information only. The
Company is not responsible and shall not be
considered liable for any damage and / or
loss that may be caused as a result of any
information contained in this presentation
and the use of this information.
In addition, this presentation may include
forward-looking information, as defined
in the Israeli Securities Law, 1968. Such
information includes, forecasts, estimates,
estimates based on other information
relating to future events and / or matters,
the realization of which is uncertain and is
not under the Company's control ("forward-
looking information."). Forward-looking
information is not a proven fact and is based
on subjective assumptions, estimates and
forecasts made by the Company at that time
only. The realization or non-realization of
the forward- looking information may be
affected from risk factors that characterize
the company's operations, as well as from
developments in the competitive and
business environment and from external
factors that influence the Company's
operations, which cannot be foreseen and
which are not controlled by the Company.
Forward-looking information is not accurate,
and the Company is unable to assess it in
advance, as most of this information is not
under its control. Therefore, this information,
in whole or in part, may change substantially
at any time as a result of the influence of
various factors, including but not limited
to changes in market conditions and / or
competition in the market and / or in the
business environment. The results and
achievements of the Company in the future
may be materially different than those
presented in the presentation. In addition,
forward-looking forecasts and evaluations
are based to update evaluations so they
would reflect events and/or circumstances
that could appear after preparing this
presentation.
2
Forward
Looking
Statements
3
Our
Mission
Cannassure's vision is to become a leading, world-class, trusted developer
and provider of top-quality medical grade cannabis products as well as
pharmaceutical cannabinoid medicines, addressing a broad range
of unmet medical needs.
Our
Vision
© Cannassure Therapeutics LtdWe do it right
Cannassure will develop and commercialize a wide range of effective,
high standard and affordable medical cannabis products as well as
pharmaceutical cannabinoid medicines, to enhance treatment and
improve people's quality of life worldwide.
This will be accomplished by facilitating a holistic integrated production
system including an advanced agritech breeding and cultivation indoor
facility, a state-of-the-art extraction and processing facility, together
with scientifically advanced R&D.
Cannassure is committed to quality, excellence, innovation and integrity.
© Cannassure Therapeutics Ltd
4
© Cannassure Therapeutics Ltd
4
Our Company
Cannassure (TASE symbol: CSURE) is launching a holistic and integrated medical cannabis
value chain operation. Activity includes breeding, cultivation, extraction, R&D and
distribution of medical cannabis products
The company was founded by Solbar Food Technologies (~ 69.5%), a leading food manufacturer
in Israel, with the intention of instilling its applied 60 years of industrial expertise and know-how
Shareholder’s equity includes ~ 51.2 Million outstanding shares and approx. 9.6 Million
tradable stock options, divided into three series, with strike price of 2-3 ILS
We do it right
© Cannassure Therapeutics Ltd
5
© Cannassure Therapeutics Ltd
5
We do it right
Major Activities So Far
In the process of extracting and processing, cannabis
oil for the purpose of developing production procedures
in the company's certified lab
In the process of constructing an advanced, agritech
indoor growing facility for cultivating uniform and
consistent flowers, based on superior breeding strains
Signed distribution agreement with Hadassah Medical
for marketing collaboration
In the process of constructing a cutting edge extraction
and processing facility
Established a highly experienced management team,
skilled in international business, bio-tech and food
manufacturing
Received initial permits from the Israeli Medical
Cannabis Authority (IMCA) for breeding, cultivating,
processing, research and development (R&D)
and storage of cannabis
Initiated preliminary development plan for unique
pharmaceutical cannabis products
Granted financial support by the Israel Innovation
Authority for the development of innovative
cannabis extraction methods
Signed binding MOU with Cannika Holdings, to
establish an agritech incubator specializing in
cannabis innovation, located within the
company's campus
© Cannassure Therapeutics Ltd
6
© Cannassure Therapeutics Ltd
6
The group invested 17.5M ILS in Cannassure
A 60-year-old leading company of high quality
botanical extractions
Customers over the years included global leading food
and pharmaceutical companies, such as Unilever,
Nestlé, Novartis, Janssen, Merck & GSK
Operates in accordance with quality standards
Annual income of 500M ILS
Cannassure is based on the
know-how and experience of
Solbar, including the extraction
and processing of botanical
extracts in a controlled
environment and manufacturing
in large industrial scale
Solbar provided Cannassure
with labs and facilities spanning
over 5,500 sqm
We do it right
Solbar Food Technologies Group
© Cannassure Therapeutics Ltd
7
© Cannassure Therapeutics Ltd
Former commander of the Israel Air Force and Head
of the IDF Planning Directorate, Mr. Nechushtan brings
extensive managerial experience, including formulating
strategy, creating work plans and leading processes.
These he performed in the Air Force, the IDF and the
private sector, in the fields of technology and cyber. He
holds a B.Sc. cum laude in Mathematics and Computer
Science from the Hebrew University of Jerusalem,
an MBA from Northwestern University and Tel Aviv
University, and an Advanced Management Program
(AMP) from Harvard University.
Having over 15 years of extensive international
experience in operations management and management
consulting, Mr. Amir has served 8 years in an executive
position at The Bread Factory, a top of the range UK
based food manufacturer, and 5 years as Solbar’s CEO.
Mr. Amir holds a B.Sc in Industrial Engineering and
Management and M.Sc in International Business from
Birkbeck, University of London.
Bringing extensive experience in drug delivery
systems and drug device combination; holding
a Ph.D in Medical Science (neurobiology) from
the Hadassah Medical School and a postdoctoral
training in neurobiology from Haifa University,
where she was appointed for a postdoctoral
fellowship, Eshkol Laurate, 2012 – 2014 on novel
approaches for Alzheimer Disease therapy. Her
field of expertise is neurodegenerative disorders.
A seasoned entrepreneur with extensive
knowledge in business development and company
transformation. A former executive at Bluephoenix
Solutions (NASDAQ: MDSY) and Alcobra Pharma
(NASDAQ: ADHD), Mr. Peles holds a BA in
Economics and Accountancy from the Hebrew
University of Jerusalem and an MBA and MA (Law)
degree from Tel Aviv and Bar Ilan Universities.
Major General Ido Nehushtan
Chairman of the Board
Ran Amir
CEO and BOD Member
Dr. Hadile Ounallah-Saad
VP R&D
Nir Peles, CPA, MBA, MA(LAW)
Founder, BOD Member
& VP Business Development
We do it right
Executive Team
© Cannassure Therapeutics Ltd
8
© Cannassure Therapeutics Ltd
Bringing 30 years of experience in leading and managing
international biomed and hi-tech companies from start-up
to market penetration and sales, including business and
clinical strategy, raising finance, technological development,
establishing marketing and sales systems. Over the
years, Steven has managed publicly traded companies
including Exalenz Bioscience (TASE: EXEN) and Micromedic
Technologies (TASE: MCTC).
Dr. Less is a multi-disciplinary, R&D professional
with unique expertise in Life Sciences, Genetics, and
Bioinformatics. He has over a decade of experience
leading R&D and operational business units for several
international companies, including Syngenta (NASDAQ:
SYENF) and Compugen (NASDAQ: CGEN). Dr. Less holds a
Ph.D from the Weizmann Institute of Sciences, Department
of Plant Science; an M.Sc in physiology and immunology
from the Israel Institute of Technology’s Faculty of Medicine;
and a B.Sc in Animal Science from the Hebrew University of
Jerusalem, Faculty of Agriculture.
With 13 years of experience in various finance
positions, Mr. Neufeld has served three years
as the CFO of Solbar Food Technologies.
Previously, Mr. Neufeld held positions at CHS
Inc (NASDAQ: CHSCP). U.S. headquarters
working for their Processing and Food
Ingredients Division and at PWC Israel. Mr.
Neufeld earned his Bachelor's Degree in
Accounting and Economics from the Ben-
Gurion University of the Negev.
With 15 years of extensive, international experience
in Quality Management and R&D, Dana has
previously served in senior management positions
in companies such as GreenMarket, China
and provided consulting services for the food
manufacturing sector. Mrs. Marom holds a B.Sc
in Biochemistry and Food Technology from the
Hebrew University of Jerusalem and an EMBA from
the College of Management Academic Studies.
Steven Eitan
VP Strategy
Dr. Hadar Less
Agri-Consultant
Adi Neufeld
CFO
Dana Marom
Chief Quality Manager
We do it right
Executive Team
© Cannassure Therapeutics Ltd
9
$28B 2024
)MarketWatch, September 2018(
Global cannabis market forecast growth
by
Major trends in the medical cannabis
global market:
Widespread recognition of the virtues and
effectiveness of medical cannabis products
Significant increase in demand for medical
cannabis treatments for dozens of medical
indications
Increased investments for research and
development of medical cannabis products
Increasing number of countries that
authorized the use and trade of medical
cannabis products
Regulatory requirements reform for the use of
medical cannabis products
Price reductions of raw cannabis yields,
highlights the major business opportunity
in the development and top-quality
extraction of innovative medical cannabis
products
We do it right
Medical Cannabis-
Opportunity and Global
Market Trends
© Cannassure Therapeutics Ltd
10
Cronos Inc CRON
Canopy Growth WEED.TO
Aurora ACB.TO
GW GWPH
Tilray TLRY
Aphria APHA
© Cannassure Therapeutics Ltd
Market Cap
Feb 1st
, 2019
Billions US dollars
Trailing 12 months
Revenues
Millions US dollars
SymbolCompany
We do it right
Leading Cannabis Companies
$3.7B
$16.8B
$7.4B
$4.5B
$7.7B
$2.4B
$9M
$73M
$60M
$13M
$33M
$47M
© Cannassure Therapeutics Ltd
11
© Cannassure Therapeutics Ltd
Development of unique medical products
Patent protected, molecular based and cannabis specific for
medical indications in large and growing global markets.
Establishing a technological incubator for medical cannabis
innovation, within the Cannassure campus, together with
Cannika Holdings
R&D
Breeding
Development of unique cannabis strains
Creating value for the medical cannabis and
pharmaceutical industries, using advanced breeding
technology
Cultivation
Building an indoor growing facility
Cultivation in a controlled environment, enabling quality
consistent yields in accordance with (IMC - GAP) standards
in 4000 sqm facility
Processing
Extraction and processing of premium quality cannabis oil
Large scale production of premium quailty cannabis oil,
cannabinoid distillation and APIs, complying with Israeli
Accreditation IMC - GMP, preparing for EU - GMP accreditation
Distribution
Distribution
An agreement with Hadassah Medical for distribution to
pharmaceutical companies, pharmacy outlets and licensed
customers, in accordance with (IMC - GDP). Exploring additional
opportunities with international affiliations
We do it right
Cannassure is
Establishing a
Comprehensive Value
Chain, Including All
Stages of Medical
Cannabis Production
© Cannassure Therapeutics Ltd
12
Cannassure is building its indoor
growing facility in accordance with
IMC - GAP agricultural standards
Indoor cultivation enables quality and consistent products and has significant advantages including:
© Cannassure Therapeutics Ltd
Increase of annual growth
cycles (approximately 6
cycles compared to 2-3
cycles in outdoor)
No exposure to
weather conditions
Higher efficiency by savings
in water and grow area
Cutlivation without
herbicides and pesticides
~ 20 tons potential
annual capacity of
cannabis flowers
The facility is being built in an existing industrial
building within the Solbar compound and will benefit
from reduced-cost electricity, natural gas supply,
reverse osmosis water supply and sewage treatment
in accordance with environmental regulation
The Cannassure Agronomy
Team brings decades of
experience of leading global
agritech companies
We do it right
Indoor Growing Facility
© Cannassure Therapeutics Ltd
13
1
2
3
© Cannassure Therapeutics Ltd
Current extraction and processing
activities in the company's lab:
Cannassure is in advanced stages of building
an IMC - GMP approved extraction facility
for controlled production of high quality oils,
cannabinoids and active pharmaceutical
ingredients, aiming for EU - GMP
The facility is being built using the accumulated
expertise, know-how and experience of Solbar Group
Developing and enhancing extraction techniques and
stability testing in the company's lab, using state-of-
the-art equipment
Developing analytical and bio-analytical techniques for
the identification of single API's
Product development is led by the company's scientific
team, supported by a leading formulator
and accompanied by leading regulatory advisors
This activity has been acknowledged as innovative by
the Israeli Innovation Authority and granted financial
support
We do it right
Medical Cannabis
Extraction and
Processing
The construction of the facility is in accordance with
the Ministry of Health's initial permit requirements
© Cannassure Therapeutics Ltd
14
Hadassah Medical-
A Strategic Partnership
for Distribution in Israel
and Commercial Activity
Expansion in International
Markets
Cannassure has signed an
agreement with Hadassah
Medical for marketing and selling
medical cannabis oil with the
Hadassah Medical brand name
in Israel and global markets
Cannassure is planning
to operate throughout
Hadassah Medical's
distribution channels,
as well as exploring more
collaborative mutual activity
We do it right
© Cannassure Therapeutics Ltd
15
© Cannassure Therapeutics Ltd
Cannassure intends to develop
and commercialize pharma-grade
products, for life threatening
diseases, in the field of oncological
gynecology, using selected, active
plant sourced cannabinoids
Cannassure is in the planning
phase of developing a new
product based on a combination
of cannabinoid active
ingredients together with an FDA
approved gynecological medical
device
A proprietary patent
application was filed
by Cannassure's expert
in pharmaceutical
intellectual property,
previously Intellectual
Property Team Manager
at Teva Pharmaceuticals
The new product development is led
by the company's scientific team,
assisted by a senior formulator
with regulatory guidance of several
leading regulatory firms
Cannassure is exploring options
for leveraging the collaboration
with Hadassah Hospital for the
development of the product
15
We do it right
Innovative Medical
Cannabis Products
Development
© Cannassure Therapeutics Ltd
16
© Cannassure Therapeutics Ltd
16
We do it right
Medical Cannabis
Innovative Center
Cannassure together with Cannika Holdings, a group
of experienced scientific experts, are establishing an
innovation center for early-stage medical cannabis
unique innovative products
1
The center will operate in Cannassure's campus,
utilizing state-of-the-art facilities, equipment,
and technologies
2
Entrepreneurs joining the innovation center will
benefit from a community of leading scientists,
researchers and business professionals
3
The innovation center activity is financed by
private investors
4
© Cannassure Therapeutics Ltd
17
© Cannassure Therapeutics Ltd
H2/20198.2018 6.2019 7.2019
17
and onwards
Extracting
medical
cannabis in
the analytical
laboratory
Completion of
extraction and
processing facility,
in accordance with
IMC - GMP regulatory
standards
Completion of
indoor grow facility
for breeding new
plant genetics
and developing
new strains, in
accordance with
IMC - GAP standards
Ready for production
and sale of IMC - GMP
approved medical
cannabis oil and
cannabis API's
We do it right
Next Steps, Key Milestones 2019
© Cannassure Therapeutics Ltd
18
Infrastructure connected to reverse osmosis water supply, natural gas and cost-reduced
electricity, allowing competitive, efficient and clean production environment
18
© Cannassure Therapeutics Ltd
Founded on the know-how, experience and expertise of Solbar Group, a leader in the
food and agriculture industry and benefits from its infrastructure and financial support
Rapidly establishing an indoor growing facility in a controlled environment, for premium
quality and consistent cannabis flowers
Rapidly establishing a highly professional complete value chain in the medical
cannabis industry
Equipped to meet and swiftly adjust to changing requirements, based on Solbar Group
know-how and experience
The global medical
cannabis industry
is undergoing
rapid growth and
development
Cannassure has clear
competitive advantages
to become a significant
entity in the medical
cannabis industry
Summary
We do it right
Strategic agreement with Hadassah Medical for collaboration and marketing of medical
cannabis products worldwide
Establishing a technological incubator for medical cannabis innovation within the
company's campus
Cannassure's Competitive Advantages
Skilled highly experienced management team in international business, bio-tech,
nutraceutical and food industries
© Cannassure Therapeutics Ltd
19
Thank You
February 2019 | Ran Amir Ran.amir@cannassure.life www.linkedin.com/company/cannassure
TASE:

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Cannassure Therapeutics Investors Deck

  • 1. Cannassure Therapeutics Ltd Investors Deck | February 2019 TASE:
  • 2. © Cannassure Therapeutics Ltd 2 © Cannassure Therapeutics LtdWe do it right This presentation has been prepared by the Company and should not be considered as a recommendation or recommendation for the purchase or sale of securities and / or investment in Cannassure Therapeutics Ltd. This presentation is intended for the purpose of providing information only. The Company is not responsible and shall not be considered liable for any damage and / or loss that may be caused as a result of any information contained in this presentation and the use of this information. In addition, this presentation may include forward-looking information, as defined in the Israeli Securities Law, 1968. Such information includes, forecasts, estimates, estimates based on other information relating to future events and / or matters, the realization of which is uncertain and is not under the Company's control ("forward- looking information."). Forward-looking information is not a proven fact and is based on subjective assumptions, estimates and forecasts made by the Company at that time only. The realization or non-realization of the forward- looking information may be affected from risk factors that characterize the company's operations, as well as from developments in the competitive and business environment and from external factors that influence the Company's operations, which cannot be foreseen and which are not controlled by the Company. Forward-looking information is not accurate, and the Company is unable to assess it in advance, as most of this information is not under its control. Therefore, this information, in whole or in part, may change substantially at any time as a result of the influence of various factors, including but not limited to changes in market conditions and / or competition in the market and / or in the business environment. The results and achievements of the Company in the future may be materially different than those presented in the presentation. In addition, forward-looking forecasts and evaluations are based to update evaluations so they would reflect events and/or circumstances that could appear after preparing this presentation. 2 Forward Looking Statements
  • 3. 3 Our Mission Cannassure's vision is to become a leading, world-class, trusted developer and provider of top-quality medical grade cannabis products as well as pharmaceutical cannabinoid medicines, addressing a broad range of unmet medical needs. Our Vision © Cannassure Therapeutics LtdWe do it right Cannassure will develop and commercialize a wide range of effective, high standard and affordable medical cannabis products as well as pharmaceutical cannabinoid medicines, to enhance treatment and improve people's quality of life worldwide. This will be accomplished by facilitating a holistic integrated production system including an advanced agritech breeding and cultivation indoor facility, a state-of-the-art extraction and processing facility, together with scientifically advanced R&D. Cannassure is committed to quality, excellence, innovation and integrity.
  • 4. © Cannassure Therapeutics Ltd 4 © Cannassure Therapeutics Ltd 4 Our Company Cannassure (TASE symbol: CSURE) is launching a holistic and integrated medical cannabis value chain operation. Activity includes breeding, cultivation, extraction, R&D and distribution of medical cannabis products The company was founded by Solbar Food Technologies (~ 69.5%), a leading food manufacturer in Israel, with the intention of instilling its applied 60 years of industrial expertise and know-how Shareholder’s equity includes ~ 51.2 Million outstanding shares and approx. 9.6 Million tradable stock options, divided into three series, with strike price of 2-3 ILS We do it right
  • 5. © Cannassure Therapeutics Ltd 5 © Cannassure Therapeutics Ltd 5 We do it right Major Activities So Far In the process of extracting and processing, cannabis oil for the purpose of developing production procedures in the company's certified lab In the process of constructing an advanced, agritech indoor growing facility for cultivating uniform and consistent flowers, based on superior breeding strains Signed distribution agreement with Hadassah Medical for marketing collaboration In the process of constructing a cutting edge extraction and processing facility Established a highly experienced management team, skilled in international business, bio-tech and food manufacturing Received initial permits from the Israeli Medical Cannabis Authority (IMCA) for breeding, cultivating, processing, research and development (R&D) and storage of cannabis Initiated preliminary development plan for unique pharmaceutical cannabis products Granted financial support by the Israel Innovation Authority for the development of innovative cannabis extraction methods Signed binding MOU with Cannika Holdings, to establish an agritech incubator specializing in cannabis innovation, located within the company's campus
  • 6. © Cannassure Therapeutics Ltd 6 © Cannassure Therapeutics Ltd 6 The group invested 17.5M ILS in Cannassure A 60-year-old leading company of high quality botanical extractions Customers over the years included global leading food and pharmaceutical companies, such as Unilever, Nestlé, Novartis, Janssen, Merck & GSK Operates in accordance with quality standards Annual income of 500M ILS Cannassure is based on the know-how and experience of Solbar, including the extraction and processing of botanical extracts in a controlled environment and manufacturing in large industrial scale Solbar provided Cannassure with labs and facilities spanning over 5,500 sqm We do it right Solbar Food Technologies Group
  • 7. © Cannassure Therapeutics Ltd 7 © Cannassure Therapeutics Ltd Former commander of the Israel Air Force and Head of the IDF Planning Directorate, Mr. Nechushtan brings extensive managerial experience, including formulating strategy, creating work plans and leading processes. These he performed in the Air Force, the IDF and the private sector, in the fields of technology and cyber. He holds a B.Sc. cum laude in Mathematics and Computer Science from the Hebrew University of Jerusalem, an MBA from Northwestern University and Tel Aviv University, and an Advanced Management Program (AMP) from Harvard University. Having over 15 years of extensive international experience in operations management and management consulting, Mr. Amir has served 8 years in an executive position at The Bread Factory, a top of the range UK based food manufacturer, and 5 years as Solbar’s CEO. Mr. Amir holds a B.Sc in Industrial Engineering and Management and M.Sc in International Business from Birkbeck, University of London. Bringing extensive experience in drug delivery systems and drug device combination; holding a Ph.D in Medical Science (neurobiology) from the Hadassah Medical School and a postdoctoral training in neurobiology from Haifa University, where she was appointed for a postdoctoral fellowship, Eshkol Laurate, 2012 – 2014 on novel approaches for Alzheimer Disease therapy. Her field of expertise is neurodegenerative disorders. A seasoned entrepreneur with extensive knowledge in business development and company transformation. A former executive at Bluephoenix Solutions (NASDAQ: MDSY) and Alcobra Pharma (NASDAQ: ADHD), Mr. Peles holds a BA in Economics and Accountancy from the Hebrew University of Jerusalem and an MBA and MA (Law) degree from Tel Aviv and Bar Ilan Universities. Major General Ido Nehushtan Chairman of the Board Ran Amir CEO and BOD Member Dr. Hadile Ounallah-Saad VP R&D Nir Peles, CPA, MBA, MA(LAW) Founder, BOD Member & VP Business Development We do it right Executive Team
  • 8. © Cannassure Therapeutics Ltd 8 © Cannassure Therapeutics Ltd Bringing 30 years of experience in leading and managing international biomed and hi-tech companies from start-up to market penetration and sales, including business and clinical strategy, raising finance, technological development, establishing marketing and sales systems. Over the years, Steven has managed publicly traded companies including Exalenz Bioscience (TASE: EXEN) and Micromedic Technologies (TASE: MCTC). Dr. Less is a multi-disciplinary, R&D professional with unique expertise in Life Sciences, Genetics, and Bioinformatics. He has over a decade of experience leading R&D and operational business units for several international companies, including Syngenta (NASDAQ: SYENF) and Compugen (NASDAQ: CGEN). Dr. Less holds a Ph.D from the Weizmann Institute of Sciences, Department of Plant Science; an M.Sc in physiology and immunology from the Israel Institute of Technology’s Faculty of Medicine; and a B.Sc in Animal Science from the Hebrew University of Jerusalem, Faculty of Agriculture. With 13 years of experience in various finance positions, Mr. Neufeld has served three years as the CFO of Solbar Food Technologies. Previously, Mr. Neufeld held positions at CHS Inc (NASDAQ: CHSCP). U.S. headquarters working for their Processing and Food Ingredients Division and at PWC Israel. Mr. Neufeld earned his Bachelor's Degree in Accounting and Economics from the Ben- Gurion University of the Negev. With 15 years of extensive, international experience in Quality Management and R&D, Dana has previously served in senior management positions in companies such as GreenMarket, China and provided consulting services for the food manufacturing sector. Mrs. Marom holds a B.Sc in Biochemistry and Food Technology from the Hebrew University of Jerusalem and an EMBA from the College of Management Academic Studies. Steven Eitan VP Strategy Dr. Hadar Less Agri-Consultant Adi Neufeld CFO Dana Marom Chief Quality Manager We do it right Executive Team
  • 9. © Cannassure Therapeutics Ltd 9 $28B 2024 )MarketWatch, September 2018( Global cannabis market forecast growth by Major trends in the medical cannabis global market: Widespread recognition of the virtues and effectiveness of medical cannabis products Significant increase in demand for medical cannabis treatments for dozens of medical indications Increased investments for research and development of medical cannabis products Increasing number of countries that authorized the use and trade of medical cannabis products Regulatory requirements reform for the use of medical cannabis products Price reductions of raw cannabis yields, highlights the major business opportunity in the development and top-quality extraction of innovative medical cannabis products We do it right Medical Cannabis- Opportunity and Global Market Trends
  • 10. © Cannassure Therapeutics Ltd 10 Cronos Inc CRON Canopy Growth WEED.TO Aurora ACB.TO GW GWPH Tilray TLRY Aphria APHA © Cannassure Therapeutics Ltd Market Cap Feb 1st , 2019 Billions US dollars Trailing 12 months Revenues Millions US dollars SymbolCompany We do it right Leading Cannabis Companies $3.7B $16.8B $7.4B $4.5B $7.7B $2.4B $9M $73M $60M $13M $33M $47M
  • 11. © Cannassure Therapeutics Ltd 11 © Cannassure Therapeutics Ltd Development of unique medical products Patent protected, molecular based and cannabis specific for medical indications in large and growing global markets. Establishing a technological incubator for medical cannabis innovation, within the Cannassure campus, together with Cannika Holdings R&D Breeding Development of unique cannabis strains Creating value for the medical cannabis and pharmaceutical industries, using advanced breeding technology Cultivation Building an indoor growing facility Cultivation in a controlled environment, enabling quality consistent yields in accordance with (IMC - GAP) standards in 4000 sqm facility Processing Extraction and processing of premium quality cannabis oil Large scale production of premium quailty cannabis oil, cannabinoid distillation and APIs, complying with Israeli Accreditation IMC - GMP, preparing for EU - GMP accreditation Distribution Distribution An agreement with Hadassah Medical for distribution to pharmaceutical companies, pharmacy outlets and licensed customers, in accordance with (IMC - GDP). Exploring additional opportunities with international affiliations We do it right Cannassure is Establishing a Comprehensive Value Chain, Including All Stages of Medical Cannabis Production
  • 12. © Cannassure Therapeutics Ltd 12 Cannassure is building its indoor growing facility in accordance with IMC - GAP agricultural standards Indoor cultivation enables quality and consistent products and has significant advantages including: © Cannassure Therapeutics Ltd Increase of annual growth cycles (approximately 6 cycles compared to 2-3 cycles in outdoor) No exposure to weather conditions Higher efficiency by savings in water and grow area Cutlivation without herbicides and pesticides ~ 20 tons potential annual capacity of cannabis flowers The facility is being built in an existing industrial building within the Solbar compound and will benefit from reduced-cost electricity, natural gas supply, reverse osmosis water supply and sewage treatment in accordance with environmental regulation The Cannassure Agronomy Team brings decades of experience of leading global agritech companies We do it right Indoor Growing Facility
  • 13. © Cannassure Therapeutics Ltd 13 1 2 3 © Cannassure Therapeutics Ltd Current extraction and processing activities in the company's lab: Cannassure is in advanced stages of building an IMC - GMP approved extraction facility for controlled production of high quality oils, cannabinoids and active pharmaceutical ingredients, aiming for EU - GMP The facility is being built using the accumulated expertise, know-how and experience of Solbar Group Developing and enhancing extraction techniques and stability testing in the company's lab, using state-of- the-art equipment Developing analytical and bio-analytical techniques for the identification of single API's Product development is led by the company's scientific team, supported by a leading formulator and accompanied by leading regulatory advisors This activity has been acknowledged as innovative by the Israeli Innovation Authority and granted financial support We do it right Medical Cannabis Extraction and Processing The construction of the facility is in accordance with the Ministry of Health's initial permit requirements
  • 14. © Cannassure Therapeutics Ltd 14 Hadassah Medical- A Strategic Partnership for Distribution in Israel and Commercial Activity Expansion in International Markets Cannassure has signed an agreement with Hadassah Medical for marketing and selling medical cannabis oil with the Hadassah Medical brand name in Israel and global markets Cannassure is planning to operate throughout Hadassah Medical's distribution channels, as well as exploring more collaborative mutual activity We do it right
  • 15. © Cannassure Therapeutics Ltd 15 © Cannassure Therapeutics Ltd Cannassure intends to develop and commercialize pharma-grade products, for life threatening diseases, in the field of oncological gynecology, using selected, active plant sourced cannabinoids Cannassure is in the planning phase of developing a new product based on a combination of cannabinoid active ingredients together with an FDA approved gynecological medical device A proprietary patent application was filed by Cannassure's expert in pharmaceutical intellectual property, previously Intellectual Property Team Manager at Teva Pharmaceuticals The new product development is led by the company's scientific team, assisted by a senior formulator with regulatory guidance of several leading regulatory firms Cannassure is exploring options for leveraging the collaboration with Hadassah Hospital for the development of the product 15 We do it right Innovative Medical Cannabis Products Development
  • 16. © Cannassure Therapeutics Ltd 16 © Cannassure Therapeutics Ltd 16 We do it right Medical Cannabis Innovative Center Cannassure together with Cannika Holdings, a group of experienced scientific experts, are establishing an innovation center for early-stage medical cannabis unique innovative products 1 The center will operate in Cannassure's campus, utilizing state-of-the-art facilities, equipment, and technologies 2 Entrepreneurs joining the innovation center will benefit from a community of leading scientists, researchers and business professionals 3 The innovation center activity is financed by private investors 4
  • 17. © Cannassure Therapeutics Ltd 17 © Cannassure Therapeutics Ltd H2/20198.2018 6.2019 7.2019 17 and onwards Extracting medical cannabis in the analytical laboratory Completion of extraction and processing facility, in accordance with IMC - GMP regulatory standards Completion of indoor grow facility for breeding new plant genetics and developing new strains, in accordance with IMC - GAP standards Ready for production and sale of IMC - GMP approved medical cannabis oil and cannabis API's We do it right Next Steps, Key Milestones 2019
  • 18. © Cannassure Therapeutics Ltd 18 Infrastructure connected to reverse osmosis water supply, natural gas and cost-reduced electricity, allowing competitive, efficient and clean production environment 18 © Cannassure Therapeutics Ltd Founded on the know-how, experience and expertise of Solbar Group, a leader in the food and agriculture industry and benefits from its infrastructure and financial support Rapidly establishing an indoor growing facility in a controlled environment, for premium quality and consistent cannabis flowers Rapidly establishing a highly professional complete value chain in the medical cannabis industry Equipped to meet and swiftly adjust to changing requirements, based on Solbar Group know-how and experience The global medical cannabis industry is undergoing rapid growth and development Cannassure has clear competitive advantages to become a significant entity in the medical cannabis industry Summary We do it right Strategic agreement with Hadassah Medical for collaboration and marketing of medical cannabis products worldwide Establishing a technological incubator for medical cannabis innovation within the company's campus Cannassure's Competitive Advantages Skilled highly experienced management team in international business, bio-tech, nutraceutical and food industries
  • 19. © Cannassure Therapeutics Ltd 19 Thank You February 2019 | Ran Amir Ran.amir@cannassure.life www.linkedin.com/company/cannassure TASE: