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Can NLP techniques be utilized as a reliable
tool for medical science? - Building a NLP
Framework
- IEEE IEMCON, 2020
Presented by: Sumaiya Tasneem
Authors:
Nafiz Sadman* Sumaiya Tasneem* Ariful Haque* Md Maminur Islam^
Md Manjurul Ahsan^^ Kishor Datta Gupta^
* Silicon Orchard Research Lab,Bangladesh
^ University of Memphis, TN, USA
^^ University of Oklahoma, Oklahoma, Australia
ROAD MAP
INTRODUCTION
OUR RESEARCH AIM
OUR PROPOSED FRAMEWORK
DATA AND EXPERIMENTAL RESULT
LIMITATIONS AND FUTURE WORK
INTRODUCTION
Remarkable Applications on NLP:
REGULAR USE APPLICATIONS SENSITIVE APPLICATIONS
1. Google Translate1 Fraud Detection System4
2 Cortana, Google Assistant, Siri2 Pattern Recognition5
3 Online Market Recommendation System and
Intelligent Chatbots like Iris3
1. P. Koehn. Statistical machine translation. Cambridge University Press, 2009.
2. Matthew B. Hoy (2018) Alexa, Siri, Cortana, and More: An Introduction to Voice Assistants, Medical Reference
Services Quarterly, 37:1, 81-88
3. E. Fast, B. Chen, J. Mendelsohn, J. Bassen, and M. S. Bernstein. Iris:A conversational agent for complex tasks. In
Proceedings of the 2018 CHI Conference on Human Factors in Computing Systems, pages 1–12, 2018.
4. N. Sadman, K. D. Gupta, A. Haque, S. Poudyal, and S. Sen. Detect review manipulation by leveraging reviewer historical
stylometrics in amazon, yelp, facebook and google reviews. In Proceedings of the 2020 The 6th International Conference
on E-Business and Applications, pages 42–47, 2020.
5. N. Sadman, K. D. Gupta, A. Haque, S. Poudyal, and S. Sen. Stylometry as a reliable method for fallback authentication. In
Proceedings of the 2020 17th International Conference on Electrical Engineer- ing/Electronics, Computer,
Telecommunications and Information Tech- nology, 2020.
Text data >> Numerical / Image data
Some medical applications using machine learning:
● Cancer Detection1
● Medical Image Analysis (CT , X - ray)2
● Genetic Sequencing3
● Gene Structure Prediction4
Field: Biomedicine , bioinformatics, genetic engineering
1.K. Kourou, T. P. Exarchos, K. P. Exarchos, M. V. Karamouzis, and D. I. Fotiadis. Machine learning applications in cancer prognosis and
prediction. Computational and structural biotechnology journal, 13:8– 17, 2015.
2. F. Ritter et al., "Medical Image Analysis," in IEEE Pulse, vol. 2, no. 6, pp. 60-70, Nov.-Dec. 2011, doi: 10.1109/MPUL.2011.942929.
3. Simon Ardui, Adam Ameur, Joris R Vermeesch, Matthew S Hestand, Single molecule real-time (SMRT) sequencing comes of age:
applications and utilities for medical diagnostics, Nucleic Acids Research, Volume 46, Issue 5, 16 March 2018, Pages 2159–2168.
3. Lee, S., Weerasinghe, W., Wray, N. et al. Using information of relatives in genomic prediction to apply effective stratified medicine. Sci
Rep 7, 42091 (2017). https://doi.org/10.1038/srep42091
Few NLP (text based) Medical Applications:
- Text mining, POS tagging, information retrieval and extraction, identification of protein or
gene names, annotations of medical records.1
- Medical document classification into groups (Ultrasonography, Endoscopy and Xray).2
- Statistical text classifier to detect extreme/risk events.3
1. M. Krallinger, R. A.-A. Erhardt, and A. Valencia. Text-mining ap-proaches in molecular biology and biomedicine.Drug
discovery today,10(6):439–445, 2005.
2. M. Khachidze, M. Tsintsadze, and M. Archuadze. Natural languageprocessing based instrument for classification of
free text medicalrecords.BioMed research international, 2016, 2016.
3. M.-S. Ong, F. Magrabi, and E. Coiera. Automated identification ofextreme-risk events in clinical incident reports.Journal
of the AmericanMedical Informatics Association, 19(e1):e110–e118, 2012
MOTIVATION BEHIND THE WORK
● Missing a dependable framework in Biomedicine field
● Less framework in NLP than Computer Vision
● Trust issues on computer driven applications
OUR RESEARCH AIM
Answer to: Can NLP techniques be utilized as a reliable tool for
medical science?
OUR PROPOSED FRAMEWORK
Data
BERT
LSTM
Naive Bayes
KNN
SVM
Random
Forest
Universal
Encoder
Weighted
Average Result
Fig: Ensemble Approach
DATA AND EXPERIMENTAL RESULT
Collection from MtSamples1
1.https://www.mtsamples.com/
Transcribed Data Medical Speciality
The left ventricular cavity size and wall thickness appear normal. The wall
motion and left ventricular systolic function appears hyperdynamic with
estimated ejection fraction of 70% to 75%....
Cardiovascular / Pulmonary
'PREOPERATIVE DIAGNOSES:,1. Hallux rigidus, left foot.,2. Elevated first
metatarsal, left foot....
Surgery
POSTOPERATIVE DIAGNOSIS: , Hallux limitus deformity of the right
foot.,ANESTHESIA:, Monitored anesthesia care with 15 mL of 1:1 mixture of
0.5% ....
Orthopedic
SUBJECTIVE:, The patient visits our office for a well-child check with concern
of some spitting up quite a bit. The patient does have some spitting up on
occasion. No projectile in nature, nonbilious....
Consult - History and Phy
Data Statistics
Maximum no of words 2460
Minimimum no of words 20
Average no of words 500
Average no of stop words 200
Fig: Class statistics
Table: Comparative performance scores of algorithms in ensemble approach
Algorithm F1 Precision Recall
Universal Encoder 0.923 0.941 0.927
BERT 0.875 0.890 0.873
Unidirectional LSTM 0.302 0.313 0.298
SVM 0.842 0.843 0.830
Random Forest 0.810 0.821 0.810
KNN 0.851 0.860 0.849
Multinomial Naive
Bayes
0.786 0.788 0.787
Publish Results from High Score Algorithms
Fig: Confusion Matrix - Universal Encoder Fig: Confusion Matrix - BERT
Fig: Confusion Matrix - KNN
LIMITATION AND FUTURE WORK
Threats to validation:
- Medical data are sensitive and must comply with HIPPA compliances1 and GDPR guidelines2. Thus
hard to collect rich and diverse dataset.
- Existance of bias due to class co-relation
Future plans:
- Improving on algorithms through hypertuning and optimizations
- Creaing a web framework, accessible to both doctors and patients
- Collaborate with hospital to collect a dependable dataset.
1. M. White. Hippa compliance for vendors and suppliers.Journalof healthcare protection management: publication of the
InternationalAssociation for Hospital Security, 30(1):91–97, 2014.
2. T. Mulder and M. Tudorica.Privacy policies, cross-border healthdata and the gdpr.Information & Communications
Technology Law,28(3):261–274, 2019
THANK YOU

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"Can NLP techniques be utilized as a reliable tool for medical science?" -Building a NLP Framework to Classify Medical Reports

  • 1. Can NLP techniques be utilized as a reliable tool for medical science? - Building a NLP Framework - IEEE IEMCON, 2020
  • 2. Presented by: Sumaiya Tasneem Authors: Nafiz Sadman* Sumaiya Tasneem* Ariful Haque* Md Maminur Islam^ Md Manjurul Ahsan^^ Kishor Datta Gupta^ * Silicon Orchard Research Lab,Bangladesh ^ University of Memphis, TN, USA ^^ University of Oklahoma, Oklahoma, Australia
  • 3. ROAD MAP INTRODUCTION OUR RESEARCH AIM OUR PROPOSED FRAMEWORK DATA AND EXPERIMENTAL RESULT LIMITATIONS AND FUTURE WORK
  • 5. Remarkable Applications on NLP: REGULAR USE APPLICATIONS SENSITIVE APPLICATIONS 1. Google Translate1 Fraud Detection System4 2 Cortana, Google Assistant, Siri2 Pattern Recognition5 3 Online Market Recommendation System and Intelligent Chatbots like Iris3 1. P. Koehn. Statistical machine translation. Cambridge University Press, 2009. 2. Matthew B. Hoy (2018) Alexa, Siri, Cortana, and More: An Introduction to Voice Assistants, Medical Reference Services Quarterly, 37:1, 81-88 3. E. Fast, B. Chen, J. Mendelsohn, J. Bassen, and M. S. Bernstein. Iris:A conversational agent for complex tasks. In Proceedings of the 2018 CHI Conference on Human Factors in Computing Systems, pages 1–12, 2018. 4. N. Sadman, K. D. Gupta, A. Haque, S. Poudyal, and S. Sen. Detect review manipulation by leveraging reviewer historical stylometrics in amazon, yelp, facebook and google reviews. In Proceedings of the 2020 The 6th International Conference on E-Business and Applications, pages 42–47, 2020. 5. N. Sadman, K. D. Gupta, A. Haque, S. Poudyal, and S. Sen. Stylometry as a reliable method for fallback authentication. In Proceedings of the 2020 17th International Conference on Electrical Engineer- ing/Electronics, Computer, Telecommunications and Information Tech- nology, 2020.
  • 6. Text data >> Numerical / Image data Some medical applications using machine learning: ● Cancer Detection1 ● Medical Image Analysis (CT , X - ray)2 ● Genetic Sequencing3 ● Gene Structure Prediction4 Field: Biomedicine , bioinformatics, genetic engineering 1.K. Kourou, T. P. Exarchos, K. P. Exarchos, M. V. Karamouzis, and D. I. Fotiadis. Machine learning applications in cancer prognosis and prediction. Computational and structural biotechnology journal, 13:8– 17, 2015. 2. F. Ritter et al., "Medical Image Analysis," in IEEE Pulse, vol. 2, no. 6, pp. 60-70, Nov.-Dec. 2011, doi: 10.1109/MPUL.2011.942929. 3. Simon Ardui, Adam Ameur, Joris R Vermeesch, Matthew S Hestand, Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics, Nucleic Acids Research, Volume 46, Issue 5, 16 March 2018, Pages 2159–2168. 3. Lee, S., Weerasinghe, W., Wray, N. et al. Using information of relatives in genomic prediction to apply effective stratified medicine. Sci Rep 7, 42091 (2017). https://doi.org/10.1038/srep42091
  • 7. Few NLP (text based) Medical Applications: - Text mining, POS tagging, information retrieval and extraction, identification of protein or gene names, annotations of medical records.1 - Medical document classification into groups (Ultrasonography, Endoscopy and Xray).2 - Statistical text classifier to detect extreme/risk events.3 1. M. Krallinger, R. A.-A. Erhardt, and A. Valencia. Text-mining ap-proaches in molecular biology and biomedicine.Drug discovery today,10(6):439–445, 2005. 2. M. Khachidze, M. Tsintsadze, and M. Archuadze. Natural languageprocessing based instrument for classification of free text medicalrecords.BioMed research international, 2016, 2016. 3. M.-S. Ong, F. Magrabi, and E. Coiera. Automated identification ofextreme-risk events in clinical incident reports.Journal of the AmericanMedical Informatics Association, 19(e1):e110–e118, 2012
  • 8. MOTIVATION BEHIND THE WORK ● Missing a dependable framework in Biomedicine field ● Less framework in NLP than Computer Vision ● Trust issues on computer driven applications
  • 10. Answer to: Can NLP techniques be utilized as a reliable tool for medical science?
  • 12.
  • 15. Collection from MtSamples1 1.https://www.mtsamples.com/ Transcribed Data Medical Speciality The left ventricular cavity size and wall thickness appear normal. The wall motion and left ventricular systolic function appears hyperdynamic with estimated ejection fraction of 70% to 75%.... Cardiovascular / Pulmonary 'PREOPERATIVE DIAGNOSES:,1. Hallux rigidus, left foot.,2. Elevated first metatarsal, left foot.... Surgery POSTOPERATIVE DIAGNOSIS: , Hallux limitus deformity of the right foot.,ANESTHESIA:, Monitored anesthesia care with 15 mL of 1:1 mixture of 0.5% .... Orthopedic SUBJECTIVE:, The patient visits our office for a well-child check with concern of some spitting up quite a bit. The patient does have some spitting up on occasion. No projectile in nature, nonbilious.... Consult - History and Phy
  • 16. Data Statistics Maximum no of words 2460 Minimimum no of words 20 Average no of words 500 Average no of stop words 200 Fig: Class statistics
  • 17. Table: Comparative performance scores of algorithms in ensemble approach Algorithm F1 Precision Recall Universal Encoder 0.923 0.941 0.927 BERT 0.875 0.890 0.873 Unidirectional LSTM 0.302 0.313 0.298 SVM 0.842 0.843 0.830 Random Forest 0.810 0.821 0.810 KNN 0.851 0.860 0.849 Multinomial Naive Bayes 0.786 0.788 0.787 Publish Results from High Score Algorithms
  • 18. Fig: Confusion Matrix - Universal Encoder Fig: Confusion Matrix - BERT Fig: Confusion Matrix - KNN
  • 20. Threats to validation: - Medical data are sensitive and must comply with HIPPA compliances1 and GDPR guidelines2. Thus hard to collect rich and diverse dataset. - Existance of bias due to class co-relation Future plans: - Improving on algorithms through hypertuning and optimizations - Creaing a web framework, accessible to both doctors and patients - Collaborate with hospital to collect a dependable dataset. 1. M. White. Hippa compliance for vendors and suppliers.Journalof healthcare protection management: publication of the InternationalAssociation for Hospital Security, 30(1):91–97, 2014. 2. T. Mulder and M. Tudorica.Privacy policies, cross-border healthdata and the gdpr.Information & Communications Technology Law,28(3):261–274, 2019