Bowel Disease
Bowel Cancer
Inflammatory Bowel
Disease (IBD) Bowel Disorders
Colon Cancer
Rectal Cancer
Anal Cancer
Crohn’s Disease
Ulcerative
Colitis
Incontinence
Diverticulitis
Fistula
Rectal Prolapse
Bowel
Obstruction
Other
Generic
Pathway
Cause
Prevention
Treatment
Containmen
t
Understanding the causes and
mechanisms of disease
Primary –removing a precursor lesion
Secondary – preventing death through
early diagnosis
Optimum investigation
Adjuvant therapies
Ensuring best quality of life – physical,
psychological and social








Learning how to combat the disease at
its inception
Cure  Ultimate eradication
Specific and non-specific treatments

Surgical procedures
Bowel
Cancer
Cause
Prevention
Treatment
Containmen
t
Genetic pre disposition
Primary – genetic monitoring and
public health initiatives
Secondary – preventing death through
early diagnosis
radiology and endoscopy
Adjuvant and neo adjuvant therapies
Chemotherapy and surgery








Environmental Factors
Cure 
Palliative care

Primary Surgical procedures – radical
and non radical
Inflammator
y Bowel
Disease
(IBD)
Cause
Prevention
Treatment
Containmen
t
Genetic factors
Radiology and Endoscopy
Drug treatments including biologicals
Ensuring best quality of life








Immune malfunction or infection
Cure  Currently there is no assured cure for
IBD
Shrink the disease with surgical and
medical treatments

Surgical procedures
Bowel
Disorders
Cause
Prevention
Treatment
Containmen
t
Age – elderly and the young,
neurological conditions
Radiology and Endoscopy
Drug & innovative less invasive
Ensuring best quality of life








Cure  Ultimate eradication
Living with the disorder but lessening
its effects

Surgical procedures
Pregnancy, injury to sphincter muscles , dietary
factors
Lifestyle
Improving obstetric care

BRUK Strategic research frameworkxx.pptx

  • 1.
    Bowel Disease Bowel Cancer InflammatoryBowel Disease (IBD) Bowel Disorders Colon Cancer Rectal Cancer Anal Cancer Crohn’s Disease Ulcerative Colitis Incontinence Diverticulitis Fistula Rectal Prolapse Bowel Obstruction Other
  • 2.
    Generic Pathway Cause Prevention Treatment Containmen t Understanding the causesand mechanisms of disease Primary –removing a precursor lesion Secondary – preventing death through early diagnosis Optimum investigation Adjuvant therapies Ensuring best quality of life – physical, psychological and social         Learning how to combat the disease at its inception Cure  Ultimate eradication Specific and non-specific treatments  Surgical procedures
  • 3.
    Bowel Cancer Cause Prevention Treatment Containmen t Genetic pre disposition Primary– genetic monitoring and public health initiatives Secondary – preventing death through early diagnosis radiology and endoscopy Adjuvant and neo adjuvant therapies Chemotherapy and surgery         Environmental Factors Cure  Palliative care  Primary Surgical procedures – radical and non radical
  • 4.
    Inflammator y Bowel Disease (IBD) Cause Prevention Treatment Containmen t Genetic factors Radiologyand Endoscopy Drug treatments including biologicals Ensuring best quality of life         Immune malfunction or infection Cure  Currently there is no assured cure for IBD Shrink the disease with surgical and medical treatments  Surgical procedures
  • 5.
    Bowel Disorders Cause Prevention Treatment Containmen t Age – elderlyand the young, neurological conditions Radiology and Endoscopy Drug & innovative less invasive Ensuring best quality of life         Cure  Ultimate eradication Living with the disorder but lessening its effects  Surgical procedures Pregnancy, injury to sphincter muscles , dietary factors Lifestyle Improving obstetric care