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A. P. John Institute for Cancer Research
The A.P. John Institute for Cancer Research was founded
in 1978 by Angelo P. John, Sr., a molecular biologist
specializing in cancer research.
A. P. John Institute for Cancer Research

The brain and spinal column make up the central nervous system (CNS), where all vital
functions of the body are controlled. When tumors arise in the central nervous system, they
are especially problematic because a persons thought processes and movements can be
affected. These tumors can also be difficult to treat because the tissues surrounding a tumor
that may be affected by surgery or radiation may play a vital role in functioning.
A. P. John Institute for Cancer Research

The grade of a tumor refers to how abnormal the cancer cells look under a microscope and
how quickly the tumor is likely to grow and spread. The pathologist determines the grade of
the tumor using tissue removed for biopsy. The following grading system may be used for
adult brain tumors:
Grade I - The tumor grows slowly, has cells that look similar to normal cells, and rarely
spreads into nearby tissues. It may be possible to remove the entire tumor by surgery.
Grade II - The tumor grows slowly, but may spread into nearby tissue and may become a
higher-grade tumor.
Grade III - The tumor grows quickly, is likely to spread into nearby tissue, and the tumor cells
look very different from normal cells.
A. P. John Institute for Cancer Research

Treatment for a brain tumor depends on a number of factors. Among these are the type,
location, and size of the tumor, as well as the patient's age and general health. Treatment
methods and schedules often vary for children and adults. A treatment plan is developed to
fit each patient's needs.
A. P. John Institute for Cancer Research

1-800-625-4190
cu@apjohncancerinstitute.org
https://www.apjohncancerinstitute.org/
A. P. John Institute for Cancer Research

1-800-625-4190
cu@apjohncancerinstitute.org
https://www.apjohncancerinstitute.org/

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Brain Cancer

  • 1. A. P. John Institute for Cancer Research The A.P. John Institute for Cancer Research was founded in 1978 by Angelo P. John, Sr., a molecular biologist specializing in cancer research.
  • 2. A. P. John Institute for Cancer Research The brain and spinal column make up the central nervous system (CNS), where all vital functions of the body are controlled. When tumors arise in the central nervous system, they are especially problematic because a persons thought processes and movements can be affected. These tumors can also be difficult to treat because the tissues surrounding a tumor that may be affected by surgery or radiation may play a vital role in functioning.
  • 3. A. P. John Institute for Cancer Research The grade of a tumor refers to how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread. The pathologist determines the grade of the tumor using tissue removed for biopsy. The following grading system may be used for adult brain tumors: Grade I - The tumor grows slowly, has cells that look similar to normal cells, and rarely spreads into nearby tissues. It may be possible to remove the entire tumor by surgery. Grade II - The tumor grows slowly, but may spread into nearby tissue and may become a higher-grade tumor. Grade III - The tumor grows quickly, is likely to spread into nearby tissue, and the tumor cells look very different from normal cells.
  • 4. A. P. John Institute for Cancer Research Treatment for a brain tumor depends on a number of factors. Among these are the type, location, and size of the tumor, as well as the patient's age and general health. Treatment methods and schedules often vary for children and adults. A treatment plan is developed to fit each patient's needs.
  • 5. A. P. John Institute for Cancer Research 1-800-625-4190 cu@apjohncancerinstitute.org https://www.apjohncancerinstitute.org/
  • 6. A. P. John Institute for Cancer Research 1-800-625-4190 cu@apjohncancerinstitute.org https://www.apjohncancerinstitute.org/