AS A LEADING-EDGE INDUSTRIAL INTEGRATOR, BOCCARD DESIGNS AND BUILDS UNIQUE PHARMACEUTICAL AND BIOTECHNOLOGY LABORATORIES THAT FACILITATE THE PRODUCTION OF ALL LIQUIDS AND SEMI-LIQUID FORMS, GELS AND CREAMS. BOCCARD IS THE INDUSTRIAL INTEGRATOR THAT BRINGS YOUR PROJECTS TO LIFE – ON TIME AND ON BUDGET

1. Pharma & Biotech
processes:
global turnkey solutions

2. 02
AS A LEADING-EDGE INDUSTRIAL INTEGRA-
TOR, BOCCARD DESIGNS AND BUILDS UNIQUE
PHARMACEUTICAL AND BIOTECHNOLOGY
LABORATORIES THAT FACILITATE THE PRO-
DUCTION OF ALL LIQUIDS AND SEMI-LIQUID
FORMS, GELS AND CREAMS. BOCCARD IS THE
INDUSTRIAL INTEGRATOR THAT BRINGS YOUR
PROJECTS TO LIFE – ON TIME AND ON BUD-
GET. AT BOCCARD, WE UNDERSTAND THE IM-
PORTANCE OF « TIME TO MARKET » REQUIRE-
MENTS. OUR COMMITTMENT TO QUALITY AND
PERFORMANCEMEANSBOCCARDALWAYSDE-
LIVERS PROCESS SOLUTIONS THAT ARE CARE-
FULLY DESIGNED TO MEET OUR CUSTOMERS
VARIED DEMANDS AND SPECIFICATIONS.
Biofermentation / Cell culture
Media preparation / Solutions
Formulation
Separation / Clarification
Purification / filtration /
Chromatography
Inactivation
Cleaning-in-Place /
Sterilization-in-Place
Decontamination
Our mission:
to design
and build
turnkey process
solutions
BOCCARD MANAGES
EACH AND EVERY STAGE
OF YOUR PROCESS
DESIGN SOLUTION

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STERILE LIQUIDS
Eye and nasal drops
Infusion solutions
Antibiotics
Vaccines
Injectable liquids
Insulin
Therapeutic proteins
Monoclonal antibodies (mAb)
Plasma derivatives:
- Albumin
- Immunoglobulin
- Factor VIII, Factor IX
DRINKABLE FORMS
Syrups
GELS & CREAMS
Hand sanitizer gels
Ointments
Suppositories
With agencies and subsidiaries in more than 30 countries,
Boccard has an outstanding ability to assist your company’s
worldwide expansion. We value long-term partnerships
and, working with our international team of skilled,
multidisciplinary project leaders, engineers and technicians,
Boccard applies an unrivalled level of knowledge and expertise.
Boccard supports your production processes by providing
a single contact person who manages your project from launch
through to delivery.
Through the rigorous application of internationally-established
best practice policies, Boccard guarantees that your project
will be managed in a responsive manner and to a high degree
of certification, in line with our PQP charter and manual:
«Prevention, Quality, and Productivity».
Because we know
how to do so within
very short timeframes,
within budget,
and anywhere
in the world,
Because we
design fully open
and independent
automated procedures
for your project,
Because we are
able to integrate
the best process
equipment,
selected jointly
with you,
Boccard
is the ideal partner
for turnkey new plant,
technology transfer,
plant extension
and GMP standard
compliance projects.

4. ATEX
CERTIFICATION
ABSOLUTE
CONFIDENTIALITY:
NDA
REALIZING YOUR IDEAS
From the very beginning of any project, our
process engineers are dedicated to implementing
your vision in line with the strictest international
regulatory requirements.
Our determination to meet the highest market
expectations means Boccard provides a performance
guarantee - we ensure your project remains within
budget and responds to your exact deliverables.
Boccard: Experts in Project Management…
Always on time, Always on spec, Always on budget.
WITH OUR PROVEN SOLUTIONS
All our skids undergo comprehensive static
and dynamic testing on our test platforms.
Boccard’s extensive experience across a vast range
of pharmaceutical facilities significantly benefits
your business; having accumulated over
20 years’ industry expertise, we use our wide-ranging
knowledge to ensure your project is equipped
with high-performance, high-tech production lines
and skids.
FOR SHARED SUCCESS
We bring together the skills that guarantee you the
best performance at each key stage of your process.
Our specialists always seek out the most innovative
technical solutions for fermentation, filtration and
separation etc.
We optimize the quality of your products, allowing
you to deliver the best possible results for your end
customers.
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«We chose Boccard/CSC for our Biotechnology plant
in Brazil because we wanted an industrial integrator
that was able to deliver a turnkey facility and provide
us with a performance guarantee. We were particularly
impressed with their expertise in the boiler-making
sector. As a company that works with plasma derivatives,
we have extremely precise requirements. »
S.J., Hemobras Project Manager, LFB Sls
Global,
high-performance solutions
that bring your ideas to life
BOCCARD ALSO OFFERS
A range of innovative solutions to simplify
your production processes:
• PPM Chromatography
• PPM Ultrafiltration
• PPM Bioreactor/Biofermenter
• PPM Block for the elimination of dead volumes
• Boclock, the intelligent process connector
• Pharmaloop water loop for PW/WFI

5. SUPPLY CHAIN CONTROLS
Boccard - Implementing
Efficient Project Management
Methodologies… Because the
success of every project also
depends on logistics, Boccard
guarantees the timely delivery
of on-site equipment, even
in unstable political or cultural
environments.
We provide reliability for
your project by prefabricating
the modules and seeking your
approval for the designs and
ergonomics prior to installation.
Thanks to our international
agency network, we can
then build these modules in
workshops located throughout
the world.
ASSISTINGYOUWORLDWIDE
Boccard - Providing a Truly
International Perspective… Having
completed projects throughout
Europe, as well as in Pakistan,
Egypt, Malaysia, Russia, Brazil,
Argentina and Algeria, Boccard
has become a globally-recognized
industrial integrator. Our
knowledge of the field combined
with our project management
expertise allows Boccard to bring
together the services of quality-
focused local subcontractors in
various international locations.
This approach provides Boccard
clients with optimal, cost-effective
solutions. Our teams are fully-
proficient in relevant industry
codes and certifications such as
ASME BPE, DESP, GMP, FDA etc.
CONSTRUCTION MODELING
To ensure effective
communication, Boccard has
established a unique design
office that acts as a platform
for collaboration and project
review - a system that is based
on the 3D modeling of part
(or all of) your plant and
of the projected facilities.
This way, you can view your
production tools before they
are built.
AT BOCCARD,
OUR SUPERB LEVEL
OF WIDE-RANGING EXPERTISE
ALLOWS US TO BRING TOGETHER
INNOVATIVE TEAMS
OF EXPERIENCED PROFESSIONALS.
THIS EXPERTISE DRIVES
THE SUCCESS
OF YOUR PROJECT!
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Turnkey technology
transfer solutions
BOCCARD IS A KEY INTERNATIONAL DESIGNER AND SUPPLIER OF INDEPENDENT MODULAR SKIDS, MODULAR
SUPER-SKIDS AND SUPERIOR QUALITY PRODUCTION PLANTS.

6. Resources and manpower:
a synergy of skills to deliver
guaranteed success
06
YOUR PROCESS: FULLY CONTROLLED
Our engineers design fully-open automation systems
that are compatible with several of the major solutions
currently available (Siemens, Rockwell, Emerson,
Wonderware, etc.). We involve your teams in the design
and ergonomics of the control system, as well as
providing training using our simulation platforms.
MAJOR MOBILIZATION CAPACITY
The team you work with during the project is the
same one that commissions your facility. Boccard is
the only industrial integrator capable of mobilizing
a start-up team featuring several dozen automation
specialists, technicians, and engineers. With our
in-depth knowledge of the process and operations
of your facility, we are able to ensure that you
receive the best possible start-up service, including
SAT tests and IQ/OQ qualification.
PROCESS ENGINEERING EXCELLENCE
For full integration of your manufacturing process,
Boccard offers excellence in engineering;
we combine superior project management know-
how with the flexibility and creativity of a LEAN,
customized design.
We are dedicated to providing guaranteed
performance and support both during and after project
implementation.
QUICK, INNOVATIVE E-QUALIFICATION
We use a unique paperless qualification documentation
system to:
- monitor commissioning tests (FAT-SAT) in real time
for projects deployed throughout the world
- optimize non-conformity management
- facilitate and speed up reporting processes (review
workflow, protocol approval, customer reports)
- standardize test progress sheets (protocols) based
on real, non-subjective data.

7. Crossflow ultrafiltration skid
Nanofiltration skid
Chromatography skid
Our expertise
in the downstream process:
protein purification
OUR RANGE OF SOLUTIONS
BUILDING ON OUR EXPERIENCE IN THE BIOTECH AND PHARMACEUTICAL SECTORS, WE HAVE DEVELOPED
A NEW HIGH-TECH RANGE OF PPM, SEPARATION AND PURIFICATION SOLUTIONS TO ISOLATE HIGH VALUE-
ADDED PROTEINS (VACCINES, INSULIN, MAB, AND PLASMA DERIVATIVES).
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Compact, modular, CIP/SIP performance,
flexible and intuitive automation system
with acceptance-testing system and
traceability, precision.
Our new range covers both laboratory
and industrial production flow rates.
It also works with our latest-generation
dilution-in-line system (up to 50 times
concentration), allowing you to reduce
the size of your buffer tanks.
Because every drop counts, we have
designed and patented new valve blocks
(PPM Block) and instruments to eliminate
dead volumes.
KEY BENEFITS

8. BOCCARD S.A.
Health Beauty Department
158 avenue Roger Salengro - BP 36080
69604 VILLEURBANNE CEDEX - France
Tél : + 33 4 37 28 12 00
Fax : +33 4 37 28 12 05
Contact : pharmaceutical@boccard.com
www.boccard.com
- Boccard has a presence in more than 30 countries worldwide -
Conception/photos:Boccard-Thinkstock
Our US address:
Boccard Life Sciences, Inc.
12559 West Airport Blvd
Sugar Land, TX 77478
Tel: +1 281 269 6020
Email: process-usa@boccard.com
Website: boccard.com