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Prevention of Sudden Cardiac Death With
Implantable Cardioverter-Defibrillators in Children
and Adolescents With Hypertrophic
Cardiomyopathy
Presented By: Jennifer Glen, Mi Hae Kim,
Rosangel Vargas
Overview
● Objectives
● Background
● Methods
● Results
● Conclusion
● Critiques
● Q&A
Objective
● To determine the efficacy of ICDs in
children and adolescents with HCM
Background
● What is HCM?
● HCM is the most
common cause
of SD in children
and young adults
Implantable Cardioverter Defibrillator (ICD)
Types of ICDs
Abbreviations and Acronyms
HCM - Hypertrophic Cardiomyopathy
ICD - Implantable Cardioverter Defibrillator
LV - Left Ventricle
LVH - Left Ventricular Hypertrophy
SD - Sudden Death
VF - Ventricular Fibrillation
VT - Ventricular Tachycardia
Methods
● Patient Selection
● Defibrillators
● Risk Factor Analysis
Results
● Baseline Characteristics
● ICD interventions /Timing
● Drugs
● Risk Factor Analysis
Discussion
● History of HCM Studies
● In this study…
o Children and Adolescents ( < 20 years )
o Effective 20 % ( ≈ 90% with No or mild Symptoms)
● Who gets ICD among HCM patients
o Extreme LVH
o Syncope
o Family History
o Hypotensive BP response to exercise
Conclusion
● Successful !
● Pros and Cons
Critiques
● Data
● Words
Reference
Maron BJ, Spirito P, Ackerman MJ, Casey SA,Semsarian C, Estes M,
Shannon KM, Ashley EA, Day SM, Pacileo G, Formisano F, Devoto E,
Anastasakis A, Bos JM, Woo A, Autore C, Pass RH, Boriani G, Garberich
RF, Almquist AK, Russell MW, Boni L, Berger S, Maron MS,Link MS.
2013. Prevention of Sudden Cardiac Death With Implantable Cardioverter-
Defilbrillators in Children and Adolescents With Hypertrophic
Cardiomyopathy. Journal of American College of Cardiology (No.14)
[Internet]. [2013 April 09, cited 2015 March 13] Vol. 61. Available from:
http://content.onlinejacc.org/mobile/article.aspx?articleid=1673454
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Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with Hypertrophic Cardio Myopathy

  • 1. Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defibrillators in Children and Adolescents With Hypertrophic Cardiomyopathy Presented By: Jennifer Glen, Mi Hae Kim, Rosangel Vargas
  • 2. Overview ● Objectives ● Background ● Methods ● Results ● Conclusion ● Critiques ● Q&A
  • 3. Objective ● To determine the efficacy of ICDs in children and adolescents with HCM
  • 4. Background ● What is HCM? ● HCM is the most common cause of SD in children and young adults
  • 7.
  • 8. Abbreviations and Acronyms HCM - Hypertrophic Cardiomyopathy ICD - Implantable Cardioverter Defibrillator LV - Left Ventricle LVH - Left Ventricular Hypertrophy SD - Sudden Death VF - Ventricular Fibrillation VT - Ventricular Tachycardia
  • 9. Methods ● Patient Selection ● Defibrillators ● Risk Factor Analysis
  • 10. Results ● Baseline Characteristics ● ICD interventions /Timing ● Drugs ● Risk Factor Analysis
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17. Discussion ● History of HCM Studies ● In this study… o Children and Adolescents ( < 20 years ) o Effective 20 % ( ≈ 90% with No or mild Symptoms) ● Who gets ICD among HCM patients o Extreme LVH o Syncope o Family History o Hypotensive BP response to exercise
  • 18.
  • 19.
  • 22. Reference Maron BJ, Spirito P, Ackerman MJ, Casey SA,Semsarian C, Estes M, Shannon KM, Ashley EA, Day SM, Pacileo G, Formisano F, Devoto E, Anastasakis A, Bos JM, Woo A, Autore C, Pass RH, Boriani G, Garberich RF, Almquist AK, Russell MW, Boni L, Berger S, Maron MS,Link MS. 2013. Prevention of Sudden Cardiac Death With Implantable Cardioverter- Defilbrillators in Children and Adolescents With Hypertrophic Cardiomyopathy. Journal of American College of Cardiology (No.14) [Internet]. [2013 April 09, cited 2015 March 13] Vol. 61. Available from: http://content.onlinejacc.org/mobile/article.aspx?articleid=1673454