This document summarizes the results of a 2010 youth survey conducted in Fairfield County, Ohio. Over 2,500 youth from 11 school districts were surveyed about their substance use, mental health, and protective factors. The survey found increases in alcohol and marijuana use, with declining age of first use and perception of harm. Prescription drug misuse is down but youth report easy access. Heroin access and use are rising concerns. Protective factors like parental involvement, clear rules, and school/community activities are linked to lower substance use rates. Continued prevention efforts through education, advocacy, and community collaboration are needed to address these issues.