course material

1. BCP401 Principles Of Pharmacology
Answers:
Questions And Answers
Young's rule is another method for calculating pediatric drug dosages in terms of a child's
age. If Ais the adult dose (in milligrams) and n is the age of the child (in years), then the
child's dose is given by
D(n) = (n / n+124)A
what is the corresponding dose for an 6-year-old child if the adult’s dose is 20mg?
120mg
7mg
6.667mg
6.5mg
Calculation
(6/ 6+12) *20
= 6.667mg
A 4-year-old patient weights 17 kg. She has been prescribed a drug that is available as a
0.5% solution and prepackaged with an oral dosing spoon embossed with a milliliter scale.
The normal adult dosage for this medication is 100 mg. What dosage should the child
receive if Clark's rule is used to calculate it?
22ml
25ml
21ml
5ml
Calculation

2. 17kg*2.2lbskg-1¬ = 37.4lbs
(37.4lbs /150)/100mg = 25 ml
Correct answer = (b) 25ml
Physicians and other medical authority officers are licensed by the health authorities to
give prescription and dosage to patients. In the list below which among them is not a
prescription label that the authority demands should be used to prescribe dosage to
patients.
Age of the prescriber
Name of the pharmacy
Address of the pharmacy
Prescription number
According to FDA, pregnancy categories are categorized according to the potential of a drug
can cause defects to the fetus. One of the pregnancy categories indicates that first time
pregnancy, no risks are involved to the fetus. Which category of pregnancy indicates that
there are no risks at all in the first trimester of pregnancy?
Category X
Category C
Category A
Category B
Which of the veterinary medications below do not require additional information during
prescription?
Oral contraceptives
Retinoids
Fertility drugs
Feed drugs
Which of the following is the function of patient- controlled analgesia?
Control rate of drug delivery to patients
Deliver drugs to patients.
Reduce dosage to the patients
Increase dosage to the patients
Of the four one is not a a manufacturer of PCA syringe system which is it?

3. Smith’s medical
ADPA tech
braun
All of the following should be done when cleaning horizontal laminar air flow hood except?
Washing hands following the appropriate procedure before cleaning the hood
Doing cleaning and disinfection
turning and running the hood before cleaning
Washing hands well after cleaning the hood.
According to electrolytes and additives, during preparation of TPN, why is dextrose and
amino acid added.
Improve Formation of body compounds to the patients
Increase appetite to patients unable to eat
Reduce potassium level in blood of the patient
Provide energy to the patient.
Which is not an equipment used during aseptic technique experiment.
Sterile 80% alcohol
Lint free wipes
Biological safety cabinet
Sterile water
If you suffer from continual vomiting and diarrhea, you could develop ______, which is
defined as abnormally high levels of sodium
Hypercalcemia
Hypernatremia
Hypermagnesemia
Because your ______ filters fluids and electrolytes, problems with it can cause fluid and
electrolyte imbalances.
Kidney
Pancreas
Liver
Thyroid
Aseptic technique refers to

4. A) cleanliness in the laboratory
B) the prevention of contamination.
C) the microbial inoculum placed into a test tube or onto a Petri plate
D) the autoclave and other sterilizing procedures.
Three of the below products contain anaesthetic except?
Dequacaine
Merocaine
BurnEze
Anthisan
all of the following products are indicated in the management of peptic ulceration EXCEPT?
Zantac
Gaviscon
Nexiumd.
Pariet
5 When administering cisplatin powder for injection:
Should be able to dissolve in water for injection
given over 6–8 h
infusion fluid used is Ringer’s solution
no powder should be used
Ceftazidime:
is a ‘third-generation’ cephalosporin antibacterial
is more active than cefuroxime against Gram-positive bacteria
is available as tablets and injections
it is very dormant
Hypothetically dangerous interactions could arise between:
ergotamine and zolmitriptan
warfarin and gliclazide
combined oral contraceptives and clindamycin
Griseofulvin and Rifampicin
which of the following is an example of enzyme inducers?

5. Griseofulvin
Rifampicin
Warfarin
Bisodol
Which of the following drugs may be used in patients with liver disease
but require a dose reduction?
Natrilix
Bisodol
Nizoral
Zyloric
Appearances of a facial abrasion that calls for referral include:
appearance of distended lymph glands in the neck
butterfly felling of a rash over the nose and cheeks
swollen lymph glands in the mouth
a scaly rash with mild erythema affecting the forehead and eyebrows
Antacid preparations comprising of sodium bicarbonate include:
A . colofac
b bisodol
Gaviscon liquid
Heartburn Relief tablets
Which of the following is an agent associated with pain and swellings after a bee sting
apamin
oestrogens
histamin
hyaluronidase
which Antispasmodics could be endorsed for itching bowel
syndrome
Colofac
Spasmonal

6. Fybogel
oestrogens
Paradichlorobenzene:
has antimycotic properties
can be used as a disinfectant
is extant in Cerumal drops
It is absent in estrogens
what dose Premarin comprise
conjugated oestrogens 625 µg
conjugated oestrogens 62.5 µg
conjugated oestrogens 0.625 µg
conjugated oestrogens 625 µg and levonorgestrel 75 µg
One of the following statement is true about mycoplasma. Which of the four is it ?
A) Annual vaccination can prevent infection.
B) The symptoms resemble pneumococcal pneumonia.
C) Treatment is tetracyclines.
D) The causative agent virus
What happens to a bacteria cell when in a hypertonic solution?
A) lyse
B) plasmolyze.
C) stay the same.
D) osmolisis
When is newsoms eyes treated with antibiotics
A) when Neisseria gonorrhoeae is isolated from the eyes
B) blind mother gives birth
C) woman with genital herpes give birth
D) when the woman is infected
You are executing a Gram stain on gram-negative bacteria and y mordant. Which colour
appears
A) rend

7. B brown
C .colorless
purple
Which of the following duos of terms is unjust?
A) sterilant terminates all living microorganisms
B) germicide destroys microbes
C) fungicide destroy yeasts and molds
D) virucide stimulates viruses
There are myths about the following drugs about how blood flow limits hepatic clearance.
Only one of them truly is?
Pethidine.
Warfarin.
Cholestyramine.
Lignocaine.
What is start order?
Medication are are to be filled within minutes
Medication thatare to be filled In hours
Medication that are to be filled in days
Medication that are to be filled in the same 24 hours.
When is importantly barcoding system apllicable
A .when administering patients
when administering medication
when choosing medication
when treating patients
why is barcode used
Make sure selected drug is the correct drug
To ensure the drug is not expired
To make sure the drug is well administered
To check if the drug is effective

8. What is the work of CADM?
Monitor and detect adverse drug events
Only monitor drug events
Only detect adverse drug events
Take record of drug events
There are 5 pricnciples of medicine taking that require discipline for the patient to heal,
following are some of them. Which is not one of the 5 right medication safety
Correct dosage
Correct time
Correct person
Correct food
Estrogen antagonists are important in to treatment of estrogen hormone-dependent
cancer. Androgen antagonists block testosterone stimulus of androgen-dependent
cancer.which of the following is an androgen-dependent cancer:
Prostate cancer.
Thyroid cancer.
Renal carcinoma.
Neuroblastoma.
Serotonin causes nausea due to the chemotherapy. Consequently, serotonin antagonists are
active in averting and treating vomit. One of the below is a serotonin. Which is it?
A Zofran
Prozac
Paxil
Zoloft
How is Methotrexate administered to treat the CNS
Intravenously
Subcutaneously
Intrathecall
By inhalation.
Methotrexate is a vitamin M antagonist. It hinders enzymes needed for production of DNA.
So as avoid damage into to the cells, folinic acid can begiven to the patient:the process is
also reffered to as?

9. Induction therapy.
Consolidation therapy.
Pulse therapy.
Rescue therapy.
process at which mutamycin is installed to traet bladder cancer is called?
Intraventricular administration.
Intravesical administration.
Intravascular administration.
Intrathecal administration.
which of the following is the dose that limit toxicity during chemotherepy
Biliousness .
Blood in stools.
Myelosuppression
stomatitis and mucositis
How does chemotherapy bring about the vomit.
stimulation of neuroreceptor in the brain
constrain catecholamines from being released
Autonomic instability.
mucus in stomach becomes irrational
Why is myeloablation using chemotherapeutic important.
It terminates myelocytes
It decreases the size of cancer tumor.
C .After operation, it decreases amount of chemotherapy required.
It extinguishes bone marrow before transplant is done
The cytochrome P450 hepatic microsomal enzyme system
is the main metabolic path for oxazepam.
is brought by phenobarbitone.
reacts with liver-kidney microsomal autoantibodies.
is subdued by cimetidine

10. Which gastric cell type has the following features: stimulates gastric acid secretion, works in
paracrine fashion, responds to gastrin, contains histamine and stains +ve with silver:
mast cells
enterochromaffin-like cell
gastrin cells
somatostatin
what Factors are to be well thought-out in venous site selection for IV therapy?
Duration of the therapy
Type of therapy
Condition of veins
All of the above
Tips for selecting veins include starting with stal veins and working
Laterally
diastally
Proximally
posteriorly
CXAn contagion in a CNS device and is not eradicated by taking antibiotics through the
catheter. In what way would glycocalyx lead to this?
Protecting the bacteria from the antibiotic.
Neutralizing hence inactivating it
By competing for binding
Glycocalyx give the microbials needed nutrients
Which one of the following is not information documented using E-MAR?
Blood pressure of patients
Rate of respiration
Infections in the mouth
Metabolic reactions in the body
Which of the following is an exception amongst the rights of medical safety?
Right dose

11. Right facility
Right person
Right condition
Which of the following is NOT true?
All drug productions should be monopolized
All medications should have barcode scans
The technicians have the ability to make codes if they are missing from the manufacturers
package
Only certified pharmacists can verify inventories
What is the job description of a pharmacy technician in an institution?
Chemotherapy-Preparing cytotoxic agents and other accompanying medications
Medical Reconciliation-Filling unit dosing bulk medications
Discharge pharmacy- Orders all supplies of medication for the pharmacy
Inventory-discharging the relevant medications
Which of the following is not the duty of a pharmacy technician in the inventory
department?
Orders all supplies of medication in the pharmacy
Rotating stock
Reviewing records for drug-drug interaction
Ordering stock and keeping records
The following is list of information contained in a drug logbook, which one is not
Drug name

12. Drug equivalent
Unit size
Drug manufacturer
Select the false statement among the following
All written records must be in pen
Any pharmacist can verify inventories
Substances that need control must be stored in a vault
Manipulation of APIs occurs in the CVE
Which generic name is correctly matched with its trade name
Ampicillin-Omnipen
Ceftazidime-Fortaz
Both of the above
None of the above
Which one of the following is a main type of hyper alimentation?
HPV
IVN
PPN
ADH
Which of the below is not a target for the production of TPNs?
Neonates
Young animals
Children

13. Adults
One of these statements is true. Which one is ?
Parenteral medications are administered by injection
Parenteral medications bypass the digestive system and are intended for instantaneous
treatment
Both of the above
None of the above
Choose an example of primary units and areas that require medication from the pharmacy
ADH
AIV
ORTHO
AIDS
The following are departments stocked with specific medications, which one is not
Preoperative
Task
Postoperative
Operation rooms
The following references can provide stability information except, which one
Trend’s stability of compound formulations
Journal of pharmaceutical sciences
The ministry of health and sanitation
USP dispensing Information

14. Select the environment terminology accurately matched with its explanation
Anteroom: Space adjacent to the buffer room
Compounding aseptic containment isolator: a glove box of class 3 which may have positive
or negative pressure
Air pressure: Space where sterile preparations are done
Laminar air flow: Space of separation between two different air pressures
Which of the following is not an example of hood used in primary engineering control based
on the sterile being produced
LAFW
BSC
CALI
CACI
Isolator hoods are not;
Glove boxes
Closed systems
Use sophisticated venting system
Chemotherapeutic agents
Which of the following is not a common task in modern pharmacies?
Bulk repackaging
Tracking medical supplies
Repackaging medications
Nonsterile compounding

15. Which of the following is an example of good manufacturing practice guidelines for
repackaging?
Keep equipment and in good condition
Package not more than one item
Inaccurate labelling
Maximum utilization of inputs to beyond use date
What is syrup
A single dose of drug
A sugar based liquid
The ingredient that is dissolved into a solution
Mixing a liquid and a solid
In the USA the FDA stands for
Food and Drug Authority
Food and Drug Administration
Food and Desertification Amendments
Famine and Desertification Authority
Identify a type of container used in preparing parenteral medications
ID
NPO
MOV
Sub out
Which of the following miscellaneous terms is properly explained?

16. Postop-Medication to be given after surgery
ID-medication to be given as required
Pm-nothing by mouth
SDV-medication to be given before surgery
Select the appropriate procedure:
Inspect all surfaces for crystallized solutions
Remove any items from within the hood
Moisten a 4 by 4inch gauze with 70% alcohol solution
Clean all surfaces inside the hood with a lint free wipe
I, II, III, IV
IV, III, II, I
II, IV, I, III
III, II, I, IV
The United States Pharmacopeia <797> contains
The procedure of cleaning horizontal laminar air flow hood
Healthcare associated infection
The campaign for compound medications
Use of nonsterile compounding