CSE
Course Code : BBOC407
MODULE : 4
Mr. Abhijith L Kotian
Assistant Professor, Dept of CSE
AIET, Moodbidri
BIOLOGY FOR ENGINEERS
NATURE-BIOINSPIRED MATERIALS
AND MECHANISMS
MODULE - 4
BIOLOGY FOR ENGINEERS
MODULE-4 (5 HOURS)
NATURE-BIOINSPIRED MATERIALS AND MECHANISMS:
 Echolocation.
 Lotus Leaf Effect.
 Plant Burrs.
 Shark Skin.
 Kingfisher Beak.
 Human Blood Substitutes.
 Self-Study Topics: Photosynthesis, Bird flying.
ECHOLOCATION
ECHOLOCATION
 Echolocation Is A Fascinating Biological Phenomenon
Observed In Various Animals, Including Bats, Dolphins &
Some Species Of Birds.
 It Involves The Emission Of Sound Waves & Interpretation
Of Echoes Reflected Back From Objects In The
Environment.
 This Ability Allows These Animals To Navigate, Perceive
Their Environment, Communicate & Locate Prey Or
Obstacles In Situations Where Vision Alone Would Be
Insufficient, Such As In Darkness Or Murky Water.
ECHOLOCATION – MECHANISM
 Sound Production: Animals Capable Of Echolocation Emit
High-Frequency Sound Waves, Often Beyond The Range
Of Human Hearing. These Sounds Are Typically Produced
In Specialized Organs Such As The Larynx Or Nasal
Passages.
 Sound Propagation: Once Emitted, These Sound Waves
Travel Through The Environment, Where They Encounter
Various Objects.
 Echo Reception: Objects In The Environment Reflect A
Portion Of The Emitted Sound Waves Back Towards The
Animal.
ECHOLOCATION – MECHANISM
 Sensory Reception: Specialized Sensory Organs, Such As
The Ears Or Other Receptor Structures, Detect These
Returning Echoes.
 Neural Processing: The Brain Processes Information
Contained In The Echoes To Create A Spatial Map Of The
Environment, Including The Size, Shape, Distance &
Movement Of Objects.
 Frequency Range: Bats Emit Ultrasonic Calls Ranging
From 20 To Over 100 kHz, Whereas Dolphins Produce
Clicks With Frequencies Typically Between 20 & 150 kHz.
ECHOLOCATION – EVOLUTIONARY ORIGINS
 Bats: They Emit Ultrasonic Calls Through Their Mouths Or
Noses & Listen To Returning Echoes With Their Sensitive
Ears.
 Cetaceans: Dolphins, Whales & Porpoises Use
Echolocation Underwater To Navigate, Communicate &
Locate Prey. They Produce High-Frequency Clicks, Which
Are Emitted Through Their Blowholes & Focused By
Structures In Their Heads. The Returning Echoes Are
Detected By Specialized Structures In Their Lower Jaw,
Allowing Them To Perceive Objects In The Water.
ECHOLOCATION – BEHAVIOURAL ECOLOGY
 Foraging: Echolocation Enables Animals To Efficiently
Locate & Capture Prey, Even In Complex Environments.
 Navigation: Echolocation Helps Animals Navigate Through
Their Habitats, Avoiding Obstacles & Locating Roosts Or
Breeding Sites.
 Communication: Echolocation Is Also Used For
Communication Within Some Species. Dolphins For
Instance, Use Different Click Patterns To Convey
Information To Each Other.
TECHNOLOGICAL APPLICATIONS OF ECHOLOCATION
 Sonar Technology: Sonar (Sound Navigation & Ranging)
Systems Are Used In Marine Navigation, Fishing &
Underwater Mapping. These Systems Emit Sound Pulses &
Detect Echoes Reflected Back From Underwater Objects.
TECHNOLOGICAL APPLICATIONS OF ECHOLOCATION
TECHNOLOGICAL APPLICATIONS OF ECHOLOCATION
Sonar Image Shows The Entrance
To Portsmouth Harbor, England.
Lower Areas Are In Blue.
Higher Areas In Red.
TECHNOLOGICAL APPLICATIONS OF ECHOLOCATION
Raw Multibeam Sonar Soundings Of The Andrea Doria (A Luxury
Ocean Liner That Tragically Sank After A Collision With The Swedish
Liner Stockholm In 1956).
TECHNOLOGICAL APPLICATIONS OF ECHOLOCATION
 Medical Imaging: Ultrasound Imaging Techniques Are
Based On Principles Similar To Echolocation. High-
Frequency Sound Waves Are Transmitted Into The Body &
The Echoes Are Used To Create Images Of Internal Organs
& Tissues.
TECHNOLOGICAL APPLICATIONS OF ECHOLOCATION
 Assistive Devices: Echolocation Inspired Devices Have
Been Developed To Assist Visually Impaired Individuals.
These Devices Emit Sound Waves & Translate The
Returning Echoes Into Spatial Information, Helping Users
Navigate Their Surroundings.
LOTUS LEAF EFFECT
LOTUS LEAF EFFECT
 The Lotus Leaf Effect Refers To The Remarkable Self-
Cleaning Ability Of Lotus Leaves To Repel Water & Dirt,
Keeping Their Surfaces Clean & Dry Even In Muddy Or Wet
Environments.
 This Natural Phenomenon Has Fascinated Scientists &
Engineers For Its Potential Applications In Developing Self-
Cleaning Surfaces, Water-Repellent Coatings & Anti-
Fouling Materials.
LOTUS LEAF EFFECT – BIOLOGICAL BASIS
 Microscopic Structures: Lotus Leaves Are Covered With Tiny
Bumps Or Papillae, Typically Ranging From 10 To 20 Micrometers
In Height.
 Nano-Scale Wax Crystals: These Papillae Are Coated With Nano-
Scale Wax Crystals, Which Are Hydrophobic (Water Repellent) &
Reduce The Contact Area Between Water Droplets & Leaf Surface.
 Cassie-Baxter State: Water Droplets On Lotus Leaves Sit In A Non-
Wetting State Known As The Cassie-Baxter State, Where They Rest
On Top Of Air Pockets Created By The Surface Structures. This
Minimizes Contact With The Solid Surface & Facilitates Easy
Rolling Off Of Water Droplets, Carrying Away Dirt Particles In The
Process.
LOTUS LEAF EFFECT – MECHANISM
 Contact Angle: Water Droplets On Lotus Leaves Exhibit A
High Contact Angle (Typically Around 150-170 Degrees),
Indicating Minimal Wetting Of The Surface.
 Low Adhesion: The Combination Of Surface Roughness &
Hydrophobicity Reduces The Adhesion Of Water Droplets
& Dirt Particles, Promoting Self-Cleaning.
 Rolling Effect: Water Droplets On Lotus Leaves Are Able
To Roll Off Easily Due To The Minimal Contact Area &
The Presence Of Air Pockets Beneath The Droplets.
LOTUS LEAF EFFECT – PRACTICAL APPLICATIONS
 Self-Cleaning Surfaces: Lotus Inspired Coatings &
Materials Are Used In Building Facades, Glass Windows &
Solar Panels To Reduce Maintenance Costs & Improve
Cleanliness.
LOTUS LEAF EFFECT – PRACTICAL APPLICATIONS
 Textiles & Fabrics: Water-Repellent Textiles Enhance
Comfort & Durability In Outdoor Apparel, Sportswear &
Protective Clothing.
LOTUS LEAF EFFECT – PRACTICAL APPLICATIONS
 Biomedical Devices: Superhydrophobic Surfaces Are
Employed In Medical Devices & Implants To Prevent
Biofouling, Bacterial Adhesion, & Contamination.
LOTUS LEAF EFFECT – PRACTICAL APPLICATIONS
 Food Packaging: Hydrophobic Coatings On Food
Packaging Materials Enhance Shelf Life By Repelling
Water & Reducing Microbial Growth.
 Environmental Applications: Lotus Inspired Materials
Contribute To Environmental Sustainability By Reducing
Water Usage In Cleaning Processes & Minimizing
Chemical Pollutants.
PLANT BURRS
PLANT BURRS
 Plant Burrs Are Specialized Seed Dispersal Mechanisms
Found In Numerous Plant Species Worldwide.
 These Structures Consist Of Small, Often Hook-Shaped Or
Barbed Appendages That Attach To Passing Animals Or
Human Clothing, Thereby Facilitating The Dispersal Of
Seeds Over Long Distances.
PLANT BURRS – TYPES
 Hooked Structures: Common In Species Like Burdock
(Arctium Spp.) & Cocklebur (Xanthium Spp.), Which Have
Robust Hooks That Latch Onto Fur Or Clothing.
 Barbed Appendages: Examples Include Cleavers (Galium
Aparine) & Some Grass Species, Which Feature Tiny,
Backward Pointing Barbs That Cling To Passing Animals.
 Velcro Like Mechanisms: Certain Plants, Such As Burr
Marigold (Bidens Spp.), Employ Tiny Bristles Or Hooks
That Interlock With Each Other & With Fabric Fibers.
PLANT BURRS – BIOLOGICAL MECHANISMS
 Adhesive Surfaces: Microscopic Structures On Burrs, Such
As Hairs, Hooks Or Barbs, Create A High-Friction Surface
That Adheres To Passing Animals Or Clothing.
 Hook & Loop Interactions: Some Plant Burrs Utilize Hook
& Loop Mechanisms, Similar To Velcro, Where Hooks On
Burr Interlock With Loops On Animal Fur Or Textile
Fibers.
 Natural Fibers & Resilience: The Materials Composing
Burrs, Often Fibrous & Resilient, Enhance Durability &
Maintain Attachment During Transport.
PLANT BURRS – PRACTICAL APPLICATIONS
 Textile Technology: Biomimetic Research On Burr
Attachment Mechanisms Has Influenced The Development
Of Improved Hook & Loop Fasteners For Textiles &
Industrial Applications.
 Material Science: Plant Inspired Adhesion Strategies Are
Utilized In The Design Of Adhesive Tapes, Bandages &
Medical Devices That Require Secure Attachment Without
Causing Damage.
PLANT BURRS – PRACTICAL APPLICATIONS
 Robotics & Engineering: Bio-Inspired Robotics
Incorporate Principles From Plant Burrs To Develop
Climbing Robots, Grippers & Mechanisms For Surface
Adhesion In Challenging Environments.
 Environmental Restoration: Understanding Burr-Mediated
Seed Dispersal Informs Restoration Practices By Promoting
Native Plant Regeneration & Controlling Invasive Species.
SHARK SKIN
SHARK SKIN
 Shark Skin Is Renowned For Its Hydrodynamic
Efficiency & Unique Structure, Which Have
Evolved Over Millions Of Years To Optimize
Swimming Performance In Marine
Environments.
 The Study Of Shark Skin Has Inspired
Innovations In Biomimetic Design, Leading To
Applications In Fields Ranging From Aerospace
Engineering To Medical Devices.
SHARK SKIN – STRUCTURE
Surface Texture: Generally, Consists
Of Overlapping Scales With Riblets Or
Grooves That Streamline Water Flow.
Dermal Denticles: Tiny Tooth Like
Structures Called Dermal Denticles
Cover The Surface Of Shark Skin.
These Denticles Are Aligned In
Specific Patterns That Reduce Drag &
Turbulence During Swimming.
 Material Properties: Shark Skin Is Composed Of Tough, Flexible
Collagen Fibers Interspersed With Mineralized Deposits, Providing
Strength & Resilience Against Mechanical Stress.
 Reduced Drag: Dermal Denticles & Surface Texture Minimize Drag
By Controlling The Flow Of Water Over The Skin, Reducing
Turbulent Eddies & Frictional Resistance, Thus Optimizing
Hydrodynamic Performance, Allowing Sharks To Maintain High
Swimming Speeds With Minimal Energy Expenditure.
 Enhanced Maneuverability: Shark Skin Allows For Agile
Movement & Precise Control During Swimming, Enabling Rapid
Acceleration, Efficient Propulsion & Efficient Energy Use.
SHARK SKIN – PROPERTIES & BIOLOGICAL MECHANISMS
SHARK SKIN – PROPERTIES & BIOLOGICAL MECHANISMS
 Noise Reduction: The Structure Of Shark Skin Reduces
Hydrodynamic Noise Generated During Swimming, Aiding
In Stealth & Predator Avoidance.
 Resistance To Biofouling: Shark Skin’s Texture & Surface
Chemistry Deter The Attachment Of Algae, Barnacles &
Other Marine Organisms, Reducing Biofouling &
Maintaining Skin Hygiene.
 Aerospace Engineering: The Design Of Aircraft Wings &
Propellers Incorporates Shark Skin Inspired Riblet
Structures To Reduce Aerodynamic Drag & Improve Fuel
Efficiency.
SHARK SKIN – BIOMIMETIC APPLICATIONS
 Marine Robotics: Underwater Vehicles & Autonomous
Drones Utilize Biomimetic Shark Skin Coatings To
Enhance Maneuverability, Speed & Stealth Capabilities.
SHARK SKIN – BIOMIMETIC APPLICATIONS
SHARK SKIN – BIOMIMETIC APPLICATIONS
 Sports Equipment: Swimsuits, Surfboards & Paddles
Feature Shark Skin Inspired Textures To Optimize
Hydrodynamic Performance & Athlete Efficiency.
SHARK SKIN – BIOMIMETIC APPLICATIONS
 Medical Devices: Biomimetic Surfaces Are Used In
Prosthetics, Implants & Surgical Instruments To Prevent
Bacterial Adhesion & Enhance Biocompatibility.
SHARK SKIN – BIOMIMETIC APPLICATIONS
 Wound Healing: Biomimetic Materials Mimic Shark Skin’s
Antimicrobial Properties To Promote Wound Healing &
Prevent Infections.
 Implant Surfaces: Prosthetic Implants & Medical Devices
Incorporate Shark Skin Inspired Coatings To Enhance
Biocompatibility & Reduce The Risk Of Rejection.
KINGFISHER BEAK
KINGFISHER BEAK
 The Kingfisher Beak Is A Specialized Anatomical
Structure Found In Kingfisher Birds, Known For
Their Piscivorous (Fish Eating) Habits & Precision
Diving Abilities.
 This Beak Is Adapted For
Capturing Prey Underwater
With Exceptional Speed &
Accuracy.
KINGFISHER BEAK – ANATOMY & STRUCTURE
 Shape & Size: The Beak Is Typically Long, Straight &
Sharply Pointed, Ideal For Plunging Into Water To Capture
Fish Swiftly.
 Hydrodynamic Design: The Streamlined Shape Of The
Beak Reduces Water Resistance During Entry & Movement
Underwater, Enhancing Diving Performance.
KINGFISHER BEAK – BIOMIMETIC INSPIRATION
 Aerospace Engineering: Biomimetic Studies On The
Kingfisher Beak Shape & Hydrodynamic Principles Inform
The Design Of Streamlined Aircraft & Drones For
Improved Aerodynamic Performance.
 Underwater Robotics: Bio-Inspired Underwater Robots
Mimic The Diving & Prey Capture Strategies Of Kingfishers,
Enhancing Maneuverability & Efficiency In Marine
Exploration.
KINGFISHER BEAK – BIOMIMETIC INSPIRATION
 Medical Devices: Biomimetic Coatings & Surface Textures
Based On The Kingfisher Beak Reduce Friction & Enhance
Biocompatibility In Surgical Instruments & Prosthetic
Implants.
 Industrial Design: Biomimetic Materials Inspired By The
Beak’s Strength & Functionality Are Utilized In
Lightweight Structures, Protective Gear & Automotive
Components.
HUMAN BLOOD SUBSTITUTES
HUMAN BLOOD SUBSTITUTES
 Blood Substitutes, Also Known As Artificial Blood Or
Oxygen Therapeutics, Are Synthetic Substances Designed
To Mimic Some Or All Of The Functions Of Natural Blood.
 These Substitutes Aim To Provide Oxygen-carrying
Capacity, Maintain Adequate Blood Volume & Potentially
Replace Whole Blood Transfusions In Medical Treatments.
HUMAN BLOOD SUBSTITUTES
 Blood Substitutes Can Be Broadly Classified Into:
 Oxygen Carriers: These Substances Primarily
Focus On Carrying & Delivering Oxygen To
Tissues.
 Volume Expanders: These Substances Increase
Blood Volume Without Carrying Oxygen, Often
Used To Stabilize Blood Pressure & Support
Circulation.
PRINCIPLES OF BLOOD SUBSTITUTES
 Oxygen Transport: Ability To Transport & Release
Oxygen To Tissues Similarly To Natural Hemoglobin.
 Viscosity & Flow Properties: Mimicking The Viscosity &
Flow Characteristics Of Natural Blood To Ensure Proper
Circulation.
 Biocompatibility: Compatibility With The Human Body To
Minimize Adverse Reactions & Side Effects.
 Longevity & Stability: Ability To Remain Effective Over
Time & Under Various Storage Conditions.
BLOOD SUBSTITUTES – CATEGORIES
 Hemoglobin-Based Oxygen Carriers (HBOCs):
 They Utilize Purified Hemoglobin Molecules Derived
From Human Or Animal Sources, Which Are Then
Modified Or Encapsulated To Enhance Stability &
Prevent Adverse Reactions.
 PerFluoroCarbon-Based Oxygen Carriers (PFCs):
 Perfluorocarbons Are Synthetic Compounds With High
Oxygen Solubility, Allowing Them To Carry & Deliver
Oxygen Effectively.
HEMOGLOBIN-BASED OXYGEN CARRIERS
 Hemoglobin-Based Oxygen Carriers Are Synthetic
Molecules Or Products Derived From Hemoglobin
That Are Designed To Transport & Deliver Oxygen
To Tissues In A Manner Similar To Natural Blood.
 They Are Developed To Address Limitations
Associated With Traditional Blood Transfusions,
Such As Donor Shortages, Blood Type Compatibility
Issues, & Risks Of Infection Transmission.
HEMOGLOBIN-BASED OXYGEN CARRIERS
 Hemoglobin-Based Oxygen Carriers (HBOCs):
 Hemoglobin-Based Oxygen Carriers Are One Of The Most
Extensively Researched Types Of Blood Substitutes.
 HBOCs Can Be:
 Chemically Modified Hemoglobins: Alterations To The
Hemoglobin Molecule To Improve Stability & Oxygen
Affinity.
 Encapsulated Hemoglobins: Hemoglobin Enclosed Within
A Lipid Or Polymer Membrane To Prevent Interaction With
Surrounding Tissues & Minimize Toxicity.
HEMOGLOBIN-BASED OXYGEN CARRIERS – PRINCIPLES
 Oxygen Binding & Release: Like Natural Hemoglobin,
HBOCs Should Effectively Bind Oxygen In The Lungs &
Release It To Tissues Under Physiological Conditions.
 Stability: They Must Maintain Stability During Storage &
Circulation To Ensure Prolonged Effectiveness.
 Biocompatibility: HBOCs Should Be Compatible With The
Human Body To Minimize Adverse Immune Responses &
Toxicity.
 Oxygen Affinity: Optimal Oxygen Affinity To Balance
Effective Oxygen Delivery With Tissue Oxygenation.
HEMOGLOBIN-BASED OXYGEN CARRIERS – TYPES
 Chemically Modified Hemoglobins:
 Chemically Modified Hemoglobins Are Derived From Natural
Hemoglobin But Undergo Chemical Alterations To Improve
Stability, Oxygen Affinity & Reduce Adverse Effects. Common
Modifications Include:
 Polymerization: Cross-Linking Hemoglobin Molecules To Form
Larger Aggregates, Enhancing Stability & Reducing Renal
Clearance.
 PEGylation: Attachment Of Polyethylene Glycol (PEG) Chains To
Hemoglobin To Increase Solubility, Reduce Antigenicity & Prolong
Circulation Time.
 Surface Modification: Coating Hemoglobin With Surfactants Or
Polymers To Improve Biocompatibility & Reduce Toxicity.
HEMOGLOBIN-BASED OXYGEN CARRIERS – TYPES
 Encapsulated Hemoglobins:
 Encapsulated Hemoglobins Involve Enclosing Purified
Hemoglobin Within A Lipid Or Polymer Membrane, Mimicking The
Structure Of Red Blood Cells. This Encapsulation Serves Several
Purposes:
 Prevention of Nitric Oxide Scavenging: Nitric Oxide (NO)
Scavenging By Free Hemoglobin Can Lead To Vasoconstriction &
Adverse Effects. Encapsulation Helps Mitigate This Issue.
 Enhanced Stability: Protection Of Hemoglobin From Degradation
& Denaturation In The Bloodstream.
 Controlled Oxygen Release: Regulation Of Oxygen Release To
Tissues Based On Physiological Demand.
HBOCs – CLINICAL APPLICATIONS
 Emergency Medicine & Trauma: Providing Immediate
Oxygen Delivery In Cases Of Severe Blood Loss Or Trauma
Where Rapid Transfusion Is Critical.
 Surgery: Supplementing Or Replacing The Need For Donor
Blood During Surgeries, Particularly In Settings Where Blood
Availability Is Limited.
 Anemia Management: Offering Alternative Treatment
Options For Patients With Chronic Anemia Who May Not Be
Suitable Candidates For Traditional Blood Transfusions.
PERFLUOROCARBON-BASED OXYGEN CARRIERS
 PerFluoroCarbon-Based Oxygen Carriers (PFCs):
 PFC-Based Blood Substitutes Do Not Rely On
Hemoglobin & Are Thus Not Subject To Issues
Like Iron Overload Or Antigenicity.
 They Work By Dissolving Oxygen In Their Liquid
Phase & Releasing It To Tissues In Need.
PERFLUOROCARBONS
 Perfluorocarbons Are Fully Fluorinated Hydrocarbons
Where All Hydrogen Atoms Have Been Replaced By
Fluorine Atoms.
 This Molecular Structure Results In Several Distinctive
Properties That Make Them Valuable In Medical &
Industrial Applications.
 In The Biomedical Field, PFCs Are Primarily Recognized
For Their High Solubility For Gases Like Oxygen & Carbon
Dioxide, Inertness & Ability To Carry & Release Gases
Effectively.
PerFluoroCarbon-Based Oxygen Carriers – PROPERTIES
 High Gas Solubility: PFCs Have A High Capacity To Dissolve
Gases Such As Oxygen & Carbon Dioxide, Which Allows Them To
Function As Effective Oxygen Carriers.
 Chemical Stability: Due To The Strong Carbon-Fluorine Bonds,
PFCs Are Highly Stable & Chemically Inert, Reducing The Risk Of
Decomposition Or Interaction With Biological Tissues.
 Low Surface Tension: PFCs Have Low Surface Tension, Which
Facilitates Their Mixing With Blood & Improves Their Ability To
Navigate Through Small Capillaries.
 Biocompatibility: PFCs Are Generally Well Tolerated By The Body
& Do Not Elicit Significant Immune Responses Or Toxicity When
Properly Formulated.
PerFluoroCarbon-Based Oxygen Carriers – PRINCIPLES
 Oxygen Transport: PFCs Should Efficiently Dissolve &
Transport Oxygen From The Lungs To Tissues, Similar To
Natural Blood.
 Gas Exchange Properties: Ability To Exchange Oxygen &
Carbon Dioxide At The Cellular Level To Support Metabolism.
 Biocompatibility: Compatibility With Biological Systems To
Avoid Adverse Reactions & Promote Safe Use.
 Longevity: Maintaining Stability & Effectiveness Over Time &
Under Various Storage Conditions.
PERFLUOROCARBON-BASED OXYGEN CARRIERS: TYPES
 Emulsions:
 Perfluorocarbon Emulsions Are Composed Of Tiny Droplets Of
PFCs Dispersed In An Aqueous Medium, Often Stabilized With
Surfactants Or Lipids.
 This Formulation Improves Biocompatibility, Stability & Facilitates
Mixing With Blood.
 Nano-Emulsions:
 Nanoemulsions Are A Specialized Form Of Emulsion Where The
Perfluorocarbon Droplets Are Significantly Smaller, Typically In
The Nanometer Range (1 mm = 10,00,000 nm).
 Nanoemulsions Offer Enhanced Stability, Prolonged Circulation
Times & Improved Tissue Penetration Compared To Larger
Emulsion Droplets.
PERFLUOROCARBONS – CLINICAL APPLICATIONS
 Blood Substitutes: Substitute For Or Supplement To
Traditional Blood Transfusions, Particularly In Situations
Where Blood Availability Or Compatibility Is Limited.
 Organ Preservation: Use In Organ Preservation
Solutions To Maintain Oxygenation During Transport &
Storage, Improving The Viability Of Organs For
Transplantation.
 Oxygen Delivery In Critical Care: Emergency Situations
Requiring Rapid Oxygen Delivery, Such As Trauma Or
Acute Respiratory Distress Syndrome (ARDS).
Any Query?
BBOC407 BIOLOGY FOR ENGINEERS (CS) - MODULE 4.pptx

BBOC407 BIOLOGY FOR ENGINEERS (CS) - MODULE 4.pptx

  • 1.
    CSE Course Code :BBOC407 MODULE : 4 Mr. Abhijith L Kotian Assistant Professor, Dept of CSE AIET, Moodbidri BIOLOGY FOR ENGINEERS
  • 2.
  • 3.
    MODULE-4 (5 HOURS) NATURE-BIOINSPIREDMATERIALS AND MECHANISMS:  Echolocation.  Lotus Leaf Effect.  Plant Burrs.  Shark Skin.  Kingfisher Beak.  Human Blood Substitutes.  Self-Study Topics: Photosynthesis, Bird flying.
  • 4.
  • 5.
    ECHOLOCATION  Echolocation IsA Fascinating Biological Phenomenon Observed In Various Animals, Including Bats, Dolphins & Some Species Of Birds.  It Involves The Emission Of Sound Waves & Interpretation Of Echoes Reflected Back From Objects In The Environment.  This Ability Allows These Animals To Navigate, Perceive Their Environment, Communicate & Locate Prey Or Obstacles In Situations Where Vision Alone Would Be Insufficient, Such As In Darkness Or Murky Water.
  • 6.
    ECHOLOCATION – MECHANISM Sound Production: Animals Capable Of Echolocation Emit High-Frequency Sound Waves, Often Beyond The Range Of Human Hearing. These Sounds Are Typically Produced In Specialized Organs Such As The Larynx Or Nasal Passages.  Sound Propagation: Once Emitted, These Sound Waves Travel Through The Environment, Where They Encounter Various Objects.  Echo Reception: Objects In The Environment Reflect A Portion Of The Emitted Sound Waves Back Towards The Animal.
  • 7.
    ECHOLOCATION – MECHANISM Sensory Reception: Specialized Sensory Organs, Such As The Ears Or Other Receptor Structures, Detect These Returning Echoes.  Neural Processing: The Brain Processes Information Contained In The Echoes To Create A Spatial Map Of The Environment, Including The Size, Shape, Distance & Movement Of Objects.  Frequency Range: Bats Emit Ultrasonic Calls Ranging From 20 To Over 100 kHz, Whereas Dolphins Produce Clicks With Frequencies Typically Between 20 & 150 kHz.
  • 9.
    ECHOLOCATION – EVOLUTIONARYORIGINS  Bats: They Emit Ultrasonic Calls Through Their Mouths Or Noses & Listen To Returning Echoes With Their Sensitive Ears.  Cetaceans: Dolphins, Whales & Porpoises Use Echolocation Underwater To Navigate, Communicate & Locate Prey. They Produce High-Frequency Clicks, Which Are Emitted Through Their Blowholes & Focused By Structures In Their Heads. The Returning Echoes Are Detected By Specialized Structures In Their Lower Jaw, Allowing Them To Perceive Objects In The Water.
  • 10.
    ECHOLOCATION – BEHAVIOURALECOLOGY  Foraging: Echolocation Enables Animals To Efficiently Locate & Capture Prey, Even In Complex Environments.  Navigation: Echolocation Helps Animals Navigate Through Their Habitats, Avoiding Obstacles & Locating Roosts Or Breeding Sites.  Communication: Echolocation Is Also Used For Communication Within Some Species. Dolphins For Instance, Use Different Click Patterns To Convey Information To Each Other.
  • 11.
    TECHNOLOGICAL APPLICATIONS OFECHOLOCATION  Sonar Technology: Sonar (Sound Navigation & Ranging) Systems Are Used In Marine Navigation, Fishing & Underwater Mapping. These Systems Emit Sound Pulses & Detect Echoes Reflected Back From Underwater Objects.
  • 12.
  • 13.
    TECHNOLOGICAL APPLICATIONS OFECHOLOCATION Sonar Image Shows The Entrance To Portsmouth Harbor, England. Lower Areas Are In Blue. Higher Areas In Red.
  • 14.
    TECHNOLOGICAL APPLICATIONS OFECHOLOCATION Raw Multibeam Sonar Soundings Of The Andrea Doria (A Luxury Ocean Liner That Tragically Sank After A Collision With The Swedish Liner Stockholm In 1956).
  • 15.
    TECHNOLOGICAL APPLICATIONS OFECHOLOCATION  Medical Imaging: Ultrasound Imaging Techniques Are Based On Principles Similar To Echolocation. High- Frequency Sound Waves Are Transmitted Into The Body & The Echoes Are Used To Create Images Of Internal Organs & Tissues.
  • 16.
    TECHNOLOGICAL APPLICATIONS OFECHOLOCATION  Assistive Devices: Echolocation Inspired Devices Have Been Developed To Assist Visually Impaired Individuals. These Devices Emit Sound Waves & Translate The Returning Echoes Into Spatial Information, Helping Users Navigate Their Surroundings.
  • 17.
  • 18.
    LOTUS LEAF EFFECT The Lotus Leaf Effect Refers To The Remarkable Self- Cleaning Ability Of Lotus Leaves To Repel Water & Dirt, Keeping Their Surfaces Clean & Dry Even In Muddy Or Wet Environments.  This Natural Phenomenon Has Fascinated Scientists & Engineers For Its Potential Applications In Developing Self- Cleaning Surfaces, Water-Repellent Coatings & Anti- Fouling Materials.
  • 19.
    LOTUS LEAF EFFECT– BIOLOGICAL BASIS  Microscopic Structures: Lotus Leaves Are Covered With Tiny Bumps Or Papillae, Typically Ranging From 10 To 20 Micrometers In Height.  Nano-Scale Wax Crystals: These Papillae Are Coated With Nano- Scale Wax Crystals, Which Are Hydrophobic (Water Repellent) & Reduce The Contact Area Between Water Droplets & Leaf Surface.  Cassie-Baxter State: Water Droplets On Lotus Leaves Sit In A Non- Wetting State Known As The Cassie-Baxter State, Where They Rest On Top Of Air Pockets Created By The Surface Structures. This Minimizes Contact With The Solid Surface & Facilitates Easy Rolling Off Of Water Droplets, Carrying Away Dirt Particles In The Process.
  • 21.
    LOTUS LEAF EFFECT– MECHANISM  Contact Angle: Water Droplets On Lotus Leaves Exhibit A High Contact Angle (Typically Around 150-170 Degrees), Indicating Minimal Wetting Of The Surface.  Low Adhesion: The Combination Of Surface Roughness & Hydrophobicity Reduces The Adhesion Of Water Droplets & Dirt Particles, Promoting Self-Cleaning.  Rolling Effect: Water Droplets On Lotus Leaves Are Able To Roll Off Easily Due To The Minimal Contact Area & The Presence Of Air Pockets Beneath The Droplets.
  • 23.
    LOTUS LEAF EFFECT– PRACTICAL APPLICATIONS  Self-Cleaning Surfaces: Lotus Inspired Coatings & Materials Are Used In Building Facades, Glass Windows & Solar Panels To Reduce Maintenance Costs & Improve Cleanliness.
  • 24.
    LOTUS LEAF EFFECT– PRACTICAL APPLICATIONS  Textiles & Fabrics: Water-Repellent Textiles Enhance Comfort & Durability In Outdoor Apparel, Sportswear & Protective Clothing.
  • 25.
    LOTUS LEAF EFFECT– PRACTICAL APPLICATIONS  Biomedical Devices: Superhydrophobic Surfaces Are Employed In Medical Devices & Implants To Prevent Biofouling, Bacterial Adhesion, & Contamination.
  • 26.
    LOTUS LEAF EFFECT– PRACTICAL APPLICATIONS  Food Packaging: Hydrophobic Coatings On Food Packaging Materials Enhance Shelf Life By Repelling Water & Reducing Microbial Growth.  Environmental Applications: Lotus Inspired Materials Contribute To Environmental Sustainability By Reducing Water Usage In Cleaning Processes & Minimizing Chemical Pollutants.
  • 27.
  • 28.
    PLANT BURRS  PlantBurrs Are Specialized Seed Dispersal Mechanisms Found In Numerous Plant Species Worldwide.  These Structures Consist Of Small, Often Hook-Shaped Or Barbed Appendages That Attach To Passing Animals Or Human Clothing, Thereby Facilitating The Dispersal Of Seeds Over Long Distances.
  • 29.
    PLANT BURRS –TYPES  Hooked Structures: Common In Species Like Burdock (Arctium Spp.) & Cocklebur (Xanthium Spp.), Which Have Robust Hooks That Latch Onto Fur Or Clothing.  Barbed Appendages: Examples Include Cleavers (Galium Aparine) & Some Grass Species, Which Feature Tiny, Backward Pointing Barbs That Cling To Passing Animals.  Velcro Like Mechanisms: Certain Plants, Such As Burr Marigold (Bidens Spp.), Employ Tiny Bristles Or Hooks That Interlock With Each Other & With Fabric Fibers.
  • 31.
    PLANT BURRS –BIOLOGICAL MECHANISMS  Adhesive Surfaces: Microscopic Structures On Burrs, Such As Hairs, Hooks Or Barbs, Create A High-Friction Surface That Adheres To Passing Animals Or Clothing.  Hook & Loop Interactions: Some Plant Burrs Utilize Hook & Loop Mechanisms, Similar To Velcro, Where Hooks On Burr Interlock With Loops On Animal Fur Or Textile Fibers.  Natural Fibers & Resilience: The Materials Composing Burrs, Often Fibrous & Resilient, Enhance Durability & Maintain Attachment During Transport.
  • 32.
    PLANT BURRS –PRACTICAL APPLICATIONS  Textile Technology: Biomimetic Research On Burr Attachment Mechanisms Has Influenced The Development Of Improved Hook & Loop Fasteners For Textiles & Industrial Applications.  Material Science: Plant Inspired Adhesion Strategies Are Utilized In The Design Of Adhesive Tapes, Bandages & Medical Devices That Require Secure Attachment Without Causing Damage.
  • 33.
    PLANT BURRS –PRACTICAL APPLICATIONS  Robotics & Engineering: Bio-Inspired Robotics Incorporate Principles From Plant Burrs To Develop Climbing Robots, Grippers & Mechanisms For Surface Adhesion In Challenging Environments.  Environmental Restoration: Understanding Burr-Mediated Seed Dispersal Informs Restoration Practices By Promoting Native Plant Regeneration & Controlling Invasive Species.
  • 34.
  • 35.
    SHARK SKIN  SharkSkin Is Renowned For Its Hydrodynamic Efficiency & Unique Structure, Which Have Evolved Over Millions Of Years To Optimize Swimming Performance In Marine Environments.  The Study Of Shark Skin Has Inspired Innovations In Biomimetic Design, Leading To Applications In Fields Ranging From Aerospace Engineering To Medical Devices.
  • 36.
    SHARK SKIN –STRUCTURE Surface Texture: Generally, Consists Of Overlapping Scales With Riblets Or Grooves That Streamline Water Flow. Dermal Denticles: Tiny Tooth Like Structures Called Dermal Denticles Cover The Surface Of Shark Skin. These Denticles Are Aligned In Specific Patterns That Reduce Drag & Turbulence During Swimming.
  • 37.
     Material Properties:Shark Skin Is Composed Of Tough, Flexible Collagen Fibers Interspersed With Mineralized Deposits, Providing Strength & Resilience Against Mechanical Stress.  Reduced Drag: Dermal Denticles & Surface Texture Minimize Drag By Controlling The Flow Of Water Over The Skin, Reducing Turbulent Eddies & Frictional Resistance, Thus Optimizing Hydrodynamic Performance, Allowing Sharks To Maintain High Swimming Speeds With Minimal Energy Expenditure.  Enhanced Maneuverability: Shark Skin Allows For Agile Movement & Precise Control During Swimming, Enabling Rapid Acceleration, Efficient Propulsion & Efficient Energy Use. SHARK SKIN – PROPERTIES & BIOLOGICAL MECHANISMS
  • 38.
    SHARK SKIN –PROPERTIES & BIOLOGICAL MECHANISMS  Noise Reduction: The Structure Of Shark Skin Reduces Hydrodynamic Noise Generated During Swimming, Aiding In Stealth & Predator Avoidance.  Resistance To Biofouling: Shark Skin’s Texture & Surface Chemistry Deter The Attachment Of Algae, Barnacles & Other Marine Organisms, Reducing Biofouling & Maintaining Skin Hygiene.
  • 39.
     Aerospace Engineering:The Design Of Aircraft Wings & Propellers Incorporates Shark Skin Inspired Riblet Structures To Reduce Aerodynamic Drag & Improve Fuel Efficiency. SHARK SKIN – BIOMIMETIC APPLICATIONS
  • 40.
     Marine Robotics:Underwater Vehicles & Autonomous Drones Utilize Biomimetic Shark Skin Coatings To Enhance Maneuverability, Speed & Stealth Capabilities. SHARK SKIN – BIOMIMETIC APPLICATIONS
  • 41.
    SHARK SKIN –BIOMIMETIC APPLICATIONS  Sports Equipment: Swimsuits, Surfboards & Paddles Feature Shark Skin Inspired Textures To Optimize Hydrodynamic Performance & Athlete Efficiency.
  • 42.
    SHARK SKIN –BIOMIMETIC APPLICATIONS  Medical Devices: Biomimetic Surfaces Are Used In Prosthetics, Implants & Surgical Instruments To Prevent Bacterial Adhesion & Enhance Biocompatibility.
  • 43.
    SHARK SKIN –BIOMIMETIC APPLICATIONS  Wound Healing: Biomimetic Materials Mimic Shark Skin’s Antimicrobial Properties To Promote Wound Healing & Prevent Infections.  Implant Surfaces: Prosthetic Implants & Medical Devices Incorporate Shark Skin Inspired Coatings To Enhance Biocompatibility & Reduce The Risk Of Rejection.
  • 44.
  • 45.
    KINGFISHER BEAK  TheKingfisher Beak Is A Specialized Anatomical Structure Found In Kingfisher Birds, Known For Their Piscivorous (Fish Eating) Habits & Precision Diving Abilities.  This Beak Is Adapted For Capturing Prey Underwater With Exceptional Speed & Accuracy.
  • 46.
    KINGFISHER BEAK –ANATOMY & STRUCTURE  Shape & Size: The Beak Is Typically Long, Straight & Sharply Pointed, Ideal For Plunging Into Water To Capture Fish Swiftly.  Hydrodynamic Design: The Streamlined Shape Of The Beak Reduces Water Resistance During Entry & Movement Underwater, Enhancing Diving Performance.
  • 47.
    KINGFISHER BEAK –BIOMIMETIC INSPIRATION  Aerospace Engineering: Biomimetic Studies On The Kingfisher Beak Shape & Hydrodynamic Principles Inform The Design Of Streamlined Aircraft & Drones For Improved Aerodynamic Performance.  Underwater Robotics: Bio-Inspired Underwater Robots Mimic The Diving & Prey Capture Strategies Of Kingfishers, Enhancing Maneuverability & Efficiency In Marine Exploration.
  • 48.
    KINGFISHER BEAK –BIOMIMETIC INSPIRATION  Medical Devices: Biomimetic Coatings & Surface Textures Based On The Kingfisher Beak Reduce Friction & Enhance Biocompatibility In Surgical Instruments & Prosthetic Implants.  Industrial Design: Biomimetic Materials Inspired By The Beak’s Strength & Functionality Are Utilized In Lightweight Structures, Protective Gear & Automotive Components.
  • 49.
  • 50.
    HUMAN BLOOD SUBSTITUTES Blood Substitutes, Also Known As Artificial Blood Or Oxygen Therapeutics, Are Synthetic Substances Designed To Mimic Some Or All Of The Functions Of Natural Blood.  These Substitutes Aim To Provide Oxygen-carrying Capacity, Maintain Adequate Blood Volume & Potentially Replace Whole Blood Transfusions In Medical Treatments.
  • 51.
    HUMAN BLOOD SUBSTITUTES Blood Substitutes Can Be Broadly Classified Into:  Oxygen Carriers: These Substances Primarily Focus On Carrying & Delivering Oxygen To Tissues.  Volume Expanders: These Substances Increase Blood Volume Without Carrying Oxygen, Often Used To Stabilize Blood Pressure & Support Circulation.
  • 52.
    PRINCIPLES OF BLOODSUBSTITUTES  Oxygen Transport: Ability To Transport & Release Oxygen To Tissues Similarly To Natural Hemoglobin.  Viscosity & Flow Properties: Mimicking The Viscosity & Flow Characteristics Of Natural Blood To Ensure Proper Circulation.  Biocompatibility: Compatibility With The Human Body To Minimize Adverse Reactions & Side Effects.  Longevity & Stability: Ability To Remain Effective Over Time & Under Various Storage Conditions.
  • 53.
    BLOOD SUBSTITUTES –CATEGORIES  Hemoglobin-Based Oxygen Carriers (HBOCs):  They Utilize Purified Hemoglobin Molecules Derived From Human Or Animal Sources, Which Are Then Modified Or Encapsulated To Enhance Stability & Prevent Adverse Reactions.  PerFluoroCarbon-Based Oxygen Carriers (PFCs):  Perfluorocarbons Are Synthetic Compounds With High Oxygen Solubility, Allowing Them To Carry & Deliver Oxygen Effectively.
  • 54.
    HEMOGLOBIN-BASED OXYGEN CARRIERS Hemoglobin-Based Oxygen Carriers Are Synthetic Molecules Or Products Derived From Hemoglobin That Are Designed To Transport & Deliver Oxygen To Tissues In A Manner Similar To Natural Blood.  They Are Developed To Address Limitations Associated With Traditional Blood Transfusions, Such As Donor Shortages, Blood Type Compatibility Issues, & Risks Of Infection Transmission.
  • 55.
    HEMOGLOBIN-BASED OXYGEN CARRIERS Hemoglobin-Based Oxygen Carriers (HBOCs):  Hemoglobin-Based Oxygen Carriers Are One Of The Most Extensively Researched Types Of Blood Substitutes.  HBOCs Can Be:  Chemically Modified Hemoglobins: Alterations To The Hemoglobin Molecule To Improve Stability & Oxygen Affinity.  Encapsulated Hemoglobins: Hemoglobin Enclosed Within A Lipid Or Polymer Membrane To Prevent Interaction With Surrounding Tissues & Minimize Toxicity.
  • 56.
    HEMOGLOBIN-BASED OXYGEN CARRIERS– PRINCIPLES  Oxygen Binding & Release: Like Natural Hemoglobin, HBOCs Should Effectively Bind Oxygen In The Lungs & Release It To Tissues Under Physiological Conditions.  Stability: They Must Maintain Stability During Storage & Circulation To Ensure Prolonged Effectiveness.  Biocompatibility: HBOCs Should Be Compatible With The Human Body To Minimize Adverse Immune Responses & Toxicity.  Oxygen Affinity: Optimal Oxygen Affinity To Balance Effective Oxygen Delivery With Tissue Oxygenation.
  • 57.
    HEMOGLOBIN-BASED OXYGEN CARRIERS– TYPES  Chemically Modified Hemoglobins:  Chemically Modified Hemoglobins Are Derived From Natural Hemoglobin But Undergo Chemical Alterations To Improve Stability, Oxygen Affinity & Reduce Adverse Effects. Common Modifications Include:  Polymerization: Cross-Linking Hemoglobin Molecules To Form Larger Aggregates, Enhancing Stability & Reducing Renal Clearance.  PEGylation: Attachment Of Polyethylene Glycol (PEG) Chains To Hemoglobin To Increase Solubility, Reduce Antigenicity & Prolong Circulation Time.  Surface Modification: Coating Hemoglobin With Surfactants Or Polymers To Improve Biocompatibility & Reduce Toxicity.
  • 58.
    HEMOGLOBIN-BASED OXYGEN CARRIERS– TYPES  Encapsulated Hemoglobins:  Encapsulated Hemoglobins Involve Enclosing Purified Hemoglobin Within A Lipid Or Polymer Membrane, Mimicking The Structure Of Red Blood Cells. This Encapsulation Serves Several Purposes:  Prevention of Nitric Oxide Scavenging: Nitric Oxide (NO) Scavenging By Free Hemoglobin Can Lead To Vasoconstriction & Adverse Effects. Encapsulation Helps Mitigate This Issue.  Enhanced Stability: Protection Of Hemoglobin From Degradation & Denaturation In The Bloodstream.  Controlled Oxygen Release: Regulation Of Oxygen Release To Tissues Based On Physiological Demand.
  • 59.
    HBOCs – CLINICALAPPLICATIONS  Emergency Medicine & Trauma: Providing Immediate Oxygen Delivery In Cases Of Severe Blood Loss Or Trauma Where Rapid Transfusion Is Critical.  Surgery: Supplementing Or Replacing The Need For Donor Blood During Surgeries, Particularly In Settings Where Blood Availability Is Limited.  Anemia Management: Offering Alternative Treatment Options For Patients With Chronic Anemia Who May Not Be Suitable Candidates For Traditional Blood Transfusions.
  • 60.
    PERFLUOROCARBON-BASED OXYGEN CARRIERS PerFluoroCarbon-Based Oxygen Carriers (PFCs):  PFC-Based Blood Substitutes Do Not Rely On Hemoglobin & Are Thus Not Subject To Issues Like Iron Overload Or Antigenicity.  They Work By Dissolving Oxygen In Their Liquid Phase & Releasing It To Tissues In Need.
  • 61.
    PERFLUOROCARBONS  Perfluorocarbons AreFully Fluorinated Hydrocarbons Where All Hydrogen Atoms Have Been Replaced By Fluorine Atoms.  This Molecular Structure Results In Several Distinctive Properties That Make Them Valuable In Medical & Industrial Applications.  In The Biomedical Field, PFCs Are Primarily Recognized For Their High Solubility For Gases Like Oxygen & Carbon Dioxide, Inertness & Ability To Carry & Release Gases Effectively.
  • 62.
    PerFluoroCarbon-Based Oxygen Carriers– PROPERTIES  High Gas Solubility: PFCs Have A High Capacity To Dissolve Gases Such As Oxygen & Carbon Dioxide, Which Allows Them To Function As Effective Oxygen Carriers.  Chemical Stability: Due To The Strong Carbon-Fluorine Bonds, PFCs Are Highly Stable & Chemically Inert, Reducing The Risk Of Decomposition Or Interaction With Biological Tissues.  Low Surface Tension: PFCs Have Low Surface Tension, Which Facilitates Their Mixing With Blood & Improves Their Ability To Navigate Through Small Capillaries.  Biocompatibility: PFCs Are Generally Well Tolerated By The Body & Do Not Elicit Significant Immune Responses Or Toxicity When Properly Formulated.
  • 63.
    PerFluoroCarbon-Based Oxygen Carriers– PRINCIPLES  Oxygen Transport: PFCs Should Efficiently Dissolve & Transport Oxygen From The Lungs To Tissues, Similar To Natural Blood.  Gas Exchange Properties: Ability To Exchange Oxygen & Carbon Dioxide At The Cellular Level To Support Metabolism.  Biocompatibility: Compatibility With Biological Systems To Avoid Adverse Reactions & Promote Safe Use.  Longevity: Maintaining Stability & Effectiveness Over Time & Under Various Storage Conditions.
  • 64.
    PERFLUOROCARBON-BASED OXYGEN CARRIERS:TYPES  Emulsions:  Perfluorocarbon Emulsions Are Composed Of Tiny Droplets Of PFCs Dispersed In An Aqueous Medium, Often Stabilized With Surfactants Or Lipids.  This Formulation Improves Biocompatibility, Stability & Facilitates Mixing With Blood.  Nano-Emulsions:  Nanoemulsions Are A Specialized Form Of Emulsion Where The Perfluorocarbon Droplets Are Significantly Smaller, Typically In The Nanometer Range (1 mm = 10,00,000 nm).  Nanoemulsions Offer Enhanced Stability, Prolonged Circulation Times & Improved Tissue Penetration Compared To Larger Emulsion Droplets.
  • 65.
    PERFLUOROCARBONS – CLINICALAPPLICATIONS  Blood Substitutes: Substitute For Or Supplement To Traditional Blood Transfusions, Particularly In Situations Where Blood Availability Or Compatibility Is Limited.  Organ Preservation: Use In Organ Preservation Solutions To Maintain Oxygenation During Transport & Storage, Improving The Viability Of Organs For Transplantation.  Oxygen Delivery In Critical Care: Emergency Situations Requiring Rapid Oxygen Delivery, Such As Trauma Or Acute Respiratory Distress Syndrome (ARDS).
  • 67.