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Spa Manager Training Ewa Goos
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120229 mol med dag jmv
This document summarizes a study comparing a new bombesin peptide antagonist (JMV4168) to agonists for targeting gastrin releasing peptide receptors (GRPR) overexpressed on prostate and breast cancers. In vitro assays showed JMV4168 bound to GRPR-expressing cells, with most radiation dose from the cell surface, unlike the agonist which was mostly internalized. In vivo studies in mice found JMV4168 had fast clearance from the pancreas and other tissues, suggesting it could be safely used for clinical imaging and treatment of GRPR-overexpressing tumors. The antagonist showed superior profile compared to agonists.
A formação de portugal
1) Os mouros tentaram conquistar a Península Ibérica em 711, mas foram derrotados pelos cristãos que reconquistaram suas terras com a ajuda de nobres franceses.
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