This study surveyed 150 students ages 10 to 18 to determine the relationship between backpack usage and back pain. 76.35% of students reported back pain validated by pain in the neck, shoulders, back, doctor visits, and reduced activity. Backpack usage, including type, weight, and time carried, was independently associated with back pain, with weight being the most dominant factor. Heavier backpacks over 10% of body weight increased risk of back pain. Females reported more intense back pain than males.