This case study follows 68-year-old Randall Swanson, who experiences a stroke characterized by garbled speech and right-sided facial droop, ultimately diagnosed with a thrombotic ischemic stroke. After timely administration of t-PA and early intervention by a multidisciplinary team, Randall shows significant improvement in neurological function during his hospital stay, culminating in his discharge to a rehabilitation facility. Continued follow-up with healthcare providers and adherence to medications and lifestyle changes are emphasized for Randall's long-term recovery.

1. Background
This case study presents a 68-year old right-handed African-American man named Randall
Swanson. He has a history of hypertension, hyperlipidemia and a history of smoking one pack per
day for the last 20 years. He is prescribed Atenolol for his HTN, and Simvastatin for
Hyperlipidemia (but he has a history of not always taking his meds). His father had a history of
hypertension and passed away from cancer 10 years ago. His mother has a history of diabetes
and is still alive.
Story
Randall was gardening with his wife on a relaxing Sunday afternoon. Out of nowhere, Randall fell
to the ground. When his wife rushed to his side and asked how he was doing, he answered with
garbled and incoherent speech. It was then that his wife noticed his face was drooping on the right
side. His wife immediately called 911 and paramedics arrived within 6 minutes. Upon initial
assessment, the paramedics reported that Randall appeared to be experiencing a stroke as he
presented with right-sided facial droop and weakness and numbness on the right side of his body.
Fortunately, Randall lived nearby a stroke center so he was transported to St. Johns Regional
Medical Center within 17 minutes of paramedics arriving to his home.
Day 1
Initial Managment
Upon arrival to the Emergency Department, the healthcare team was ready to work together to
diagnose Randall. He was placed in bed with the HOB elevated to 30 degrees to decrease
intracranial pressure and reduce any risks for aspiration. Randalls wife remained at his side and
provided the care team with his brief medical history which as previously mentioned, consists of
hypertension, hyperlipidemia and smoking one pack per day for the last 20 years. He had no
recent head trauma, never had a stroke, no prior surgeries, and no use of anticoagulation
medications.
Physical Assessment
Upon first impression, Nurse Laura recognized that Randall was calm but looked apprehensive.
When asked to state his name and date of birth, his speech sounded garbled at times and was
very slow, but he could still be understood. He could not recall the month he was born in but he
was alert and oriented to person, time, and situation. When asked to state where he was, he could
not recall the word hospital. He simply pointed around the room while repeating here.
Further assessment revealed that his pupils were equal and reactive to light and that he presented
with right-sided facial paralysis. Randall was able to follow commands but when asked to move his
extremities, he could not lift his right arm and leg. He also reported that he could not feel the nurse
touch his right arm and leg. Nurse Laura gathered the initial vital signs as follows: BP: 176/82, HR:
93, RR: 20, T:99.4, O2: 92% RA and a headache with pain of 3/10.
Doctors Orders
The doctor orders were quickly noted and included:
-2L O2 (to keep O2 >93%)
500 mL Bolus NS
VS Q2h for the first 8 hrs.
-Draw labs for: CBC, INR, PT/INR, PTT, and Troponin

2. -Get an EKG
-Chest X ray
-CT
-Glucose check
-Obtain patient weight
-Perform a National Institute of Health Stroke Scale (also known as NIHSS) Q12h for the first 24
hours, then Q24h until he is discharged
-Notify pharmacy of potential t-PA preparation.
Nursing Actions
Nurse Laura started an 18 gauge IV in Randalls left AC and started him on a bolus of 500 mL of
NS. A blood sample was collected and quickly sent to the lab. Nurse Laura called the Emergency
Department Tech to obtain a 12 lead EKG.
Pertinent Lab Results for Randall
The physician and the nurse review the labs:
WBC 7.3 x 10^9/L
RBC 4.6 x 10^12/L
Plt 200 x 10^9/L
LDL 179 mg/dL
HDL 43 mg/dL
PT 12 sec
PTT 29 sec
INR 1.2
Troponin <0.01 ng/mL
Glucose 94
EKG and Chest X Ray Results
The EKG results and monitor revealed Randall was in normal sinus rhythm; CXR was negative for
pulmonary or cardiac pathology
CT Scan and NIHSS Results
The NIH Stroke Scale was completed and demonstrated that Randall had significant neurological
deficits with a score of 13. Within 20 minutes of arrival to the hospital, Randall had a CT-scan
completed. Within 40 minutes of arrival to the hospital, the radiologist notified the ED physician
that the CT-scan was negative for any active bleeding, ruling our hemorrhagic stroke.
Plan
The doctors consulted and diagnosed Randall with a thrombotic ischemic stroke and determined
that that plan would include administering t-PA. Since Randalls CT scan was negative for a bleed
and since he met all of the inclusion criteria he was a candidate for t-PA. (Some of the inclusion
criteria includes that the last time the patient is seen normal must be within 3 hours, the CT scan
has to be negative for bleeding, the patient must be 18 years or older, the doctor must make the
diagnosis of an acute ischemic stroke, and the patient must continue to present with neurological
deficits.)
Since the neurologist has recommended IV t-PA, the physicians went into Randalls room and
discussed what they found with him and his wife. Nurse Laura answered and addressed any

3. remaining concerns or questions.
Administration
Randall and his wife decided to proceed with t-PA therapy as ordered, therefore Nurse Laura
initiated the hospitals t-PA protocol. A bolus of 6.73 mg of tPA was administered for 1 minute
followed by an infusion of 60.59 mg over the course of 1 hour. (This was determined by his weight
of 74.8 kg). After the infusion was complete, Randall was transferred to the ICU for close
observation. Upon reassessment of the patient, Randall still appeared to be displaying
neurological deficits and his right-sided paralysis had not improved. His vital signs were assessed
and noted as follows: BP: 149/79 HR: 90 RR: 18 T:98.9 O2: 97% 2L NC Pain: 2/10.
Randalls wife was crying and he appeared very scared, so Nurse John tried to provide as much
emotional support to them as possible. Nurse John paid close attention to Randalls blood pressure
since he could be at risk for hemorrhaging due to the medication. Randall was also continually
assessed for any changes in neurological status and allergic reactions to the t-PA. Nurse John
made sure that Stroke Core Measures were followed in order to enhance Randalls outcome.
Day 2
Assessment
In the ICU, Randalls neurological status improved greatly. Nurse Jan noted that while he still
garbled speech and right-sided facial droop, he was now able to recall information such as his
birthday and he could identify objects when asked. Randall was able to move his right arm and leg
off the bed but he reported that he was still experiencing decreased sensation, right-sided
weakness and he demonstrated drift in both extremities.
The nurse monitored Randalls blood pressure and noted that it was higher than normal at 151/83.
She realized this was an expected finding for a patient during a stroke but systolic pressure should
be maintained at less than 185 to lower the risk of hemorrhage. His vitals remained stable and his
NIHSS score decreased to an 8. Labs were drawn and were WNL with the exception of his LDL
and HDL levels. His vital signs were noted as follows: BP 151/80 HR 92 RR 18 T 98.8 O2 97% RA
Pain 0/10
Orders
The Doctor ordered Physical, Speech, and Occupational therapy, as well as a swallow test.
Swallowing Screen
Randall remained NPO since his arrival due to the risks associated with swallowing after a stroke.
Nurse Jan performed a swallow test by giving Randall 3 ounces of water. On the first sip, Randall
coughed and subsequently did not pass. Nurse Jan kept him NPO until the speech pathologist
arrived to further evaluate Randall. Ultimately, the speech pathologist determined that with due
caution, Randall could be put on a dysphagia diet that featured thickened liquids
Physical Therapy & Occupational Therapy
A physical therapist worked with Randall and helped him to carry out passive range of motion
exercises. An occupational therapist also worked with Randall to evaluate how well he could
perform tasks such as writing, getting dressed and bathing. It was important for these therapy
measures to begin as soon as possible to increase the functional outcomes for Randall.
Rehabilitation is an ongoing process that begins in the acute setting.
Day 3- third person

4. During Day 3, Randalls last day in the ICU, Nurse Jessica performed his assessment. His vital
signs remained stable and WNL as follows: BP: 135/79 HR: 90 RR: 18 T: 98.9 O2: 97% on RA,
and Pain 0/10. His NIHSS dramatically decreased to a 2. Randall began showing signs of
improved neurological status; he was able to follow commands appropriately and was alert and
oriented x 4. The strength in his right arm and leg markedly improved. he was able to lift both his
right arm and leg well and while he still reported feeling a little weakness and sensory loss, the
drift in both extremities was absent.
Rehabilitation Therapies
Physical, speech, and occupational therapists continued to work with Randall. He was able to call
for assistance and ambulate with a walker to the bathroom and back. He was able to clean his
face with a washcloth, dress with minimal assistance, brush his teeth, and more. Randall
continued to talk with slurred speech but he was able to enunciate with effort.
Day 4
On day 4, Randall was transferred to the med-surg floor to continue progression. He continued to
work with physical and occupational therapy and was able to perform most of his ADLs with little
assistance. Randall could also ambulate 20 feet down the hall with the use of a walker.
Day 5
Long-Term Rehabilitation and Ongoing Care
On day 5, Randall was discharged to a rehabilitation facility and continued to display daily
improvement. The dysphagia that he previously was experiencing resolved and he was
discharged home 1.5 weeks later. Luckily for Randall, his wife was there to witness his last known
well time and she was able to notify first responders. They arrived quickly and he was able to
receive t-PA in a timely manner. With the help of the interdisciplinary team consisting of nurses,
therapists, doctors, and other personnel, Randall was put on the path to not only recover from the
stroke but also to quickly regain function and quality of life very near to pre-stroke levels. It is now
important that Randall continues to follow up with his primary doctor and his neurologist and that
he adheres to his medication and physical therapy regimen.
Case Management
During Randalls stay, Mary the case manager played a crucial role in Randalls path to recovery.
She determined that primary areas of concern included his history of medical noncompliance and
unhealthy lifestyle. The case manager consulted with Dietary and requested that they provide
Randall with education on a healthy diet regimen. She also provided him with smoking cessation
information. Since Randall has been noncompliant with his medications, Mary determined that
social services should consult with him to figure out what the reasons were behind his
noncompliance. Social Services reported back to Mary that Randall stated that he didnt really
understand why he needed to take the medication. It was apparent that he had not been properly
educated. Mary also needed to work with Randalls insurance to ensure that he could go to the
rehab facility as she knew this would greatly impact his ultimate outcome. Lastly, throughout his
stay, the case manager provided Randall and his wife with resources on stroke educational
materials. With the collaboration of nurses, education on the benefits of smoking cessation,
medication adherence, lifestyle modifications, and stroke recognition was reiterated to the couple.
After discharge, the case manager also checked up with Randall to make sure that he complied

5. with his follow up appointments with the neurologist and physical and speech therapists,
Questions
What risk factors contributed to Randalls stroke?
What types of contraindications could have prevented Randall from receiving t-PA?
What factors attributed to Randalls overall favorable outcome?