The Pet Pooja app is an Android application that aims to spread awareness about complementary feeding in rural areas through animation and voice support. Based on the date of birth entered, mothers will receive one of three messages - for pregnant women informing when they can use the app after delivery, for mothers of babies under 6 months informing when they can use the app, and for mothers of babies over 6 months showing ingredients for complementary feeding. The app then provides instructions on how to cook nutritious foods, consistency checks, appropriate quantities, and feeding frequencies.
Presentation at the ESWC 2011 PhD Symposium in May 2011, by Michael Schneider, FZI. Included are backup slides that have not been presented at the event. The corresponding PhD proposal can be found in the ESWC proceedings at <http: />. Alternatively, the PhD proposal can be downloaded from <http: />.
The document summarizes the work of Liz Savage and Susan Mileto in researching open source tools for instructional designers and creating a resource book for their client, Greg Walsh. They explored a variety of open source tools for graphics, audio, video, page layout and more. They wrote descriptions of each tool, created tutorials, and shared their work through Google Docs to collaborate remotely. Their goal was to broaden their knowledge of open source e-learning tools and enhance their own instructional practice.
Unicat is the National Serials Union Catalogue of China that contains bibliographic and holdings information from over 400 research libraries. ScienceChina is a service system that integrates Chinese science journal articles, references, and relationships through its Chinese Science Citation Database and other subdatabases. It provides citation analysis and metrics to evaluate academic influence. Both systems aim to improve discovery, access, and analysis of Chinese research literature.
Elipse Analysis and Design offers high-value ICT solutions and user experiences. It provides a full range of services including app development, augmented reality, virtual tours and more. ElipseAD specializes in augmented reality technologies and owns its own solutions in this field. It develops mobile and desktop applications using augmented reality as a channel for transmitting content to customers.
La Unión Europea ha anunciado nuevas sanciones contra Rusia por su invasión de Ucrania. Las sanciones incluyen prohibiciones de viaje y congelamiento de activos para más funcionarios rusos, así como restricciones a las importaciones de productos rusos de acero y tecnología. Los líderes de la UE esperan que estas medidas adicionales aumenten la presión sobre Rusia para poner fin a su guerra contra Ucrania.
This document summarizes the layout and features of a 3400 Kentch Road home in Festus. The home has a dining room, living room overlooking an atrium, a gourmet kitchen, breakfast room, and a large master suite with a see-through fireplace and private deck. It also has two additional bedrooms, a recreation room, media room, and unfinished storage areas. The 10-acre property has views of the surrounding 45 acres, which are also available for purchase.
The Pet Pooja app is an Android application that aims to spread awareness about complementary feeding in rural areas through animation and voice support. Based on the date of birth entered, mothers will receive one of three messages - for pregnant women informing when they can use the app after delivery, for mothers of babies under 6 months informing when they can use the app, and for mothers of babies over 6 months showing ingredients for complementary feeding. The app then provides instructions on how to cook nutritious foods, consistency checks, appropriate quantities, and feeding frequencies.
Presentation at the ESWC 2011 PhD Symposium in May 2011, by Michael Schneider, FZI. Included are backup slides that have not been presented at the event. The corresponding PhD proposal can be found in the ESWC proceedings at <http: />. Alternatively, the PhD proposal can be downloaded from <http: />.
The document summarizes the work of Liz Savage and Susan Mileto in researching open source tools for instructional designers and creating a resource book for their client, Greg Walsh. They explored a variety of open source tools for graphics, audio, video, page layout and more. They wrote descriptions of each tool, created tutorials, and shared their work through Google Docs to collaborate remotely. Their goal was to broaden their knowledge of open source e-learning tools and enhance their own instructional practice.
Unicat is the National Serials Union Catalogue of China that contains bibliographic and holdings information from over 400 research libraries. ScienceChina is a service system that integrates Chinese science journal articles, references, and relationships through its Chinese Science Citation Database and other subdatabases. It provides citation analysis and metrics to evaluate academic influence. Both systems aim to improve discovery, access, and analysis of Chinese research literature.
Elipse Analysis and Design offers high-value ICT solutions and user experiences. It provides a full range of services including app development, augmented reality, virtual tours and more. ElipseAD specializes in augmented reality technologies and owns its own solutions in this field. It develops mobile and desktop applications using augmented reality as a channel for transmitting content to customers.
La Unión Europea ha anunciado nuevas sanciones contra Rusia por su invasión de Ucrania. Las sanciones incluyen prohibiciones de viaje y congelamiento de activos para más funcionarios rusos, así como restricciones a las importaciones de productos rusos de acero y tecnología. Los líderes de la UE esperan que estas medidas adicionales aumenten la presión sobre Rusia para poner fin a su guerra contra Ucrania.
This document summarizes the layout and features of a 3400 Kentch Road home in Festus. The home has a dining room, living room overlooking an atrium, a gourmet kitchen, breakfast room, and a large master suite with a see-through fireplace and private deck. It also has two additional bedrooms, a recreation room, media room, and unfinished storage areas. The 10-acre property has views of the surrounding 45 acres, which are also available for purchase.
The document discusses intelligent environments and how the brain processes information. It mentions innovation week and notes that it's about more than just a remote control.
The AAA Foundation for Traffic Safety conducted the 2009 Traffic Safety Culture Index survey to investigate the public's traffic safety knowledge, attitudes, behaviors and experiences. The survey was a random telephone sample of over 2,500 US residents age 16 and older. Key findings included that the majority of drivers do not feel safer than 5 years ago, with distracted driving such as cell phone use being a major reason. The survey also found high percentages of drivers admitting to cell phone use and texting while driving despite viewing them as serious safety threats. The AAA Foundation will use the survey results to guide traffic safety research, education and policy discussions.
This document summarizes Nicholas Carr's 2008 article "Is Google Making Us Stupid?" which argues that the internet is changing how people read and process information. It presents an experiment where students had trouble concentrating while reading online. However, there is little scientific evidence so far to support Carr's claims. The document also discusses how search algorithms and Google's dominance shape the way people find and consume information on the internet.
La lista incluye varios objetos y conceptos como avión, abeja, abuelos, colores como amarillo y azul, el arcoíris, una araña, un árbol, agua, un anillo y un aguacate, así como una ardilla.
F.L.O is a marketing campaign to support local Arizona businesses by giving them advertising opportunities through television, social media, and video emails at discounted rates. Participating businesses can offer deals or contribute prizes to giveaways to get exposure. The campaign aims to strengthen community ties and local economies by encouraging customers to shop locally.
Traffic Expert conducts regular workshops to coach the basics of the search engine optimization. We hope you have the chance to attend one of these days, if not, we are glad to be sharing the slides here.
As a business owner or marketing professional, it is useful to understand the basics of search engines in order to do effective Internet marketing.
Traffic Expert provides Internet Marketing solution from Search, Social and Mobile. Any questions, visit www.trafficexpert.com.sg or contact us at support@trafficexpert.com.sg.
A empresa de tecnologia anunciou um novo produto revolucionário que usa inteligência artificial para automatizar tarefas domésticas. O dispositivo pode limpar, cozinhar e fazer compras sozinho, poupando tempo dos usuários. No entanto, alguns especialistas levantaram preocupações sobre a segurança e o impacto no mercado de trabalho à medida que mais tarefas são automatizadas.
This document summarizes tools and tactics for engaging alumni using an alumni association website built on the open-source Joomla platform. It discusses using Joomla, Google, and content feeds to provide easy navigation, social media resources, and updates. Chapter and club sections take advantage of standard content and styles while being tailored individually and using Google Calendar and YouTube. Facebook, LinkedIn, Twitter, and YouTube are integrated to engage alumni and leverage free resources. Two segmented eNewsletters are sent on different schedules to reduce overcommunication while spotlighting programs, services, and events. New engagement ideas discussed include using Foursquare, a Knight Neighbor Locator, and a mobile app campaign.
Este documento describe la duración anormal del embarazo, incluyendo definiciones de embarazo tardío, embarazo postérmino y nacimiento postérmino. Explica la incidencia, factores de riesgo, complicaciones como macrosomía y distocia de hombros, síndrome de postmadurez, manejo con vigilancia fetal e inducción del parto, y alteraciones del crecimiento y bienestar fetal como restricción del crecimiento intrauterino.
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She became interested in the topic after helping a patient suffering from postpartum depression from having a daughter instead of a son. Through extensive research, she developed her own methodology and was able to successfully select the gender of her first child, a girl. Word of her success spread and she went on to help over 100 other couples select the gender of their choice through her natural approach. She now offers her guide for sale, promising it provides a simple, risk-free, and effective means for choosing a baby's gender through natural preconception methods. She backs it with a money-back guarantee.
How to be a son or daughter good mothersonordaughter
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She describes her experience as a midwife witnessing a mother's postpartum depression after having a third daughter instead of a desired son, which motivated her research. She developed a methodology by studying many natural gender selection techniques and applying it successfully to her own pregnancy and many others', achieving the desired gender 112 out of 117 times. She now offers this guide as an e-book to help others plan their perfect families, with a money-back guarantee.
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She describes her experience as a midwife witnessing a mother's postpartum depression after having a third daughter instead of a desired son, which motivated her research. She tested gender selection methods on herself successfully and has since helped over 100 other couples conceive babies of the desired gender. She now offers an e-book compiling this research and promises a 100% money back guarantee.
How to be a son or daughter good muslimsonordaughter
This document introduces a guide for choosing a baby's gender through natural preconception methods. The author became interested in gender selection after her experience as a midwife with a mother suffering from postpartum depression from having a daughter instead of a son. Through extensive research of natural methods, the author developed her own methodology and successfully used it to conceive a daughter. She then helped over 100 other couples conceive babies of the desired gender through this risk-free and natural approach. The author has compiled her findings into an e-book to help others create their dream families and achieve the perfect baby through gender selection. She offers a money-back guarantee if customers are not satisfied with the guide's contents and results.
This document introduces a guide for choosing a baby's gender through natural preconception methods. The author became interested in gender selection after her experience as a midwife with a mother suffering from postpartum depression from having a daughter instead of a son. Through extensive research of natural methods, the author developed her own methodology and successfully used it to conceive a daughter. She then helped over 100 other couples conceive babies of the desired gender. The author now offers an e-book compiling her findings and gender selection methods, with a money-back guarantee.
How to be a son or daughter good teenagesonordaughter
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She became interested in the topic after a patient suffered from postpartum depression from having a third daughter instead of a son. Through extensive research, she developed her own methodology and was able to conceive a daughter using it. Many couples who tried her natural methods were also successful in having babies of the desired gender. She now offers her guide for sale to help others achieve their dream families through pre-conception gender selection. The guide claims to provide reliable, effective and risk-free natural methods backed by a money-back guarantee.
How to be a son or daughter good mom to teenagesonordaughter
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She became interested in the topic after helping a patient suffering from postpartum depression from having a daughter instead of a son. Through extensive research, she developed her own methodology and was able to conceive a daughter using it. Many couples she helped were also successful in having babies of the desired gender. She now offers her guide as an e-book to help others looking to naturally select their baby's gender in a safe, risk-free way. The guide claims over a 90% success rate based on her experiences helping over 100 couples.
Pregnancy womb school 1st trimester part 2Jeanette McVoy
This document discusses the benefits of prenatal stimulation for babies' development. Statistically significant improvements have been shown in babies' IQ, language abilities, musical/creative abilities, attention spans, sleep patterns, and early motor skills from stimulation provided at the right times and methods. Surprisingly, these benefits increased over the first 6 years of life rather than diminishing after birth. Bonding and love between parent and baby were reported as even greater benefits than developmental advantages. The document describes how parents were able to communicate with babies through touch patterns before birth, strengthening bonding.
The document discusses intelligent environments and how the brain processes information. It mentions innovation week and notes that it's about more than just a remote control.
The AAA Foundation for Traffic Safety conducted the 2009 Traffic Safety Culture Index survey to investigate the public's traffic safety knowledge, attitudes, behaviors and experiences. The survey was a random telephone sample of over 2,500 US residents age 16 and older. Key findings included that the majority of drivers do not feel safer than 5 years ago, with distracted driving such as cell phone use being a major reason. The survey also found high percentages of drivers admitting to cell phone use and texting while driving despite viewing them as serious safety threats. The AAA Foundation will use the survey results to guide traffic safety research, education and policy discussions.
This document summarizes Nicholas Carr's 2008 article "Is Google Making Us Stupid?" which argues that the internet is changing how people read and process information. It presents an experiment where students had trouble concentrating while reading online. However, there is little scientific evidence so far to support Carr's claims. The document also discusses how search algorithms and Google's dominance shape the way people find and consume information on the internet.
La lista incluye varios objetos y conceptos como avión, abeja, abuelos, colores como amarillo y azul, el arcoíris, una araña, un árbol, agua, un anillo y un aguacate, así como una ardilla.
F.L.O is a marketing campaign to support local Arizona businesses by giving them advertising opportunities through television, social media, and video emails at discounted rates. Participating businesses can offer deals or contribute prizes to giveaways to get exposure. The campaign aims to strengthen community ties and local economies by encouraging customers to shop locally.
Traffic Expert conducts regular workshops to coach the basics of the search engine optimization. We hope you have the chance to attend one of these days, if not, we are glad to be sharing the slides here.
As a business owner or marketing professional, it is useful to understand the basics of search engines in order to do effective Internet marketing.
Traffic Expert provides Internet Marketing solution from Search, Social and Mobile. Any questions, visit www.trafficexpert.com.sg or contact us at support@trafficexpert.com.sg.
A empresa de tecnologia anunciou um novo produto revolucionário que usa inteligência artificial para automatizar tarefas domésticas. O dispositivo pode limpar, cozinhar e fazer compras sozinho, poupando tempo dos usuários. No entanto, alguns especialistas levantaram preocupações sobre a segurança e o impacto no mercado de trabalho à medida que mais tarefas são automatizadas.
This document summarizes tools and tactics for engaging alumni using an alumni association website built on the open-source Joomla platform. It discusses using Joomla, Google, and content feeds to provide easy navigation, social media resources, and updates. Chapter and club sections take advantage of standard content and styles while being tailored individually and using Google Calendar and YouTube. Facebook, LinkedIn, Twitter, and YouTube are integrated to engage alumni and leverage free resources. Two segmented eNewsletters are sent on different schedules to reduce overcommunication while spotlighting programs, services, and events. New engagement ideas discussed include using Foursquare, a Knight Neighbor Locator, and a mobile app campaign.
Este documento describe la duración anormal del embarazo, incluyendo definiciones de embarazo tardío, embarazo postérmino y nacimiento postérmino. Explica la incidencia, factores de riesgo, complicaciones como macrosomía y distocia de hombros, síndrome de postmadurez, manejo con vigilancia fetal e inducción del parto, y alteraciones del crecimiento y bienestar fetal como restricción del crecimiento intrauterino.
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She became interested in the topic after helping a patient suffering from postpartum depression from having a daughter instead of a son. Through extensive research, she developed her own methodology and was able to successfully select the gender of her first child, a girl. Word of her success spread and she went on to help over 100 other couples select the gender of their choice through her natural approach. She now offers her guide for sale, promising it provides a simple, risk-free, and effective means for choosing a baby's gender through natural preconception methods. She backs it with a money-back guarantee.
How to be a son or daughter good mothersonordaughter
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She describes her experience as a midwife witnessing a mother's postpartum depression after having a third daughter instead of a desired son, which motivated her research. She developed a methodology by studying many natural gender selection techniques and applying it successfully to her own pregnancy and many others', achieving the desired gender 112 out of 117 times. She now offers this guide as an e-book to help others plan their perfect families, with a money-back guarantee.
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She describes her experience as a midwife witnessing a mother's postpartum depression after having a third daughter instead of a desired son, which motivated her research. She tested gender selection methods on herself successfully and has since helped over 100 other couples conceive babies of the desired gender. She now offers an e-book compiling this research and promises a 100% money back guarantee.
How to be a son or daughter good muslimsonordaughter
This document introduces a guide for choosing a baby's gender through natural preconception methods. The author became interested in gender selection after her experience as a midwife with a mother suffering from postpartum depression from having a daughter instead of a son. Through extensive research of natural methods, the author developed her own methodology and successfully used it to conceive a daughter. She then helped over 100 other couples conceive babies of the desired gender through this risk-free and natural approach. The author has compiled her findings into an e-book to help others create their dream families and achieve the perfect baby through gender selection. She offers a money-back guarantee if customers are not satisfied with the guide's contents and results.
This document introduces a guide for choosing a baby's gender through natural preconception methods. The author became interested in gender selection after her experience as a midwife with a mother suffering from postpartum depression from having a daughter instead of a son. Through extensive research of natural methods, the author developed her own methodology and successfully used it to conceive a daughter. She then helped over 100 other couples conceive babies of the desired gender. The author now offers an e-book compiling her findings and gender selection methods, with a money-back guarantee.
How to be a son or daughter good teenagesonordaughter
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She became interested in the topic after a patient suffered from postpartum depression from having a third daughter instead of a son. Through extensive research, she developed her own methodology and was able to conceive a daughter using it. Many couples who tried her natural methods were also successful in having babies of the desired gender. She now offers her guide for sale to help others achieve their dream families through pre-conception gender selection. The guide claims to provide reliable, effective and risk-free natural methods backed by a money-back guarantee.
How to be a son or daughter good mom to teenagesonordaughter
This document is a letter from a midwife promoting her guide on natural baby gender selection methods. She became interested in the topic after helping a patient suffering from postpartum depression from having a daughter instead of a son. Through extensive research, she developed her own methodology and was able to conceive a daughter using it. Many couples she helped were also successful in having babies of the desired gender. She now offers her guide as an e-book to help others looking to naturally select their baby's gender in a safe, risk-free way. The guide claims over a 90% success rate based on her experiences helping over 100 couples.
Pregnancy womb school 1st trimester part 2Jeanette McVoy
This document discusses the benefits of prenatal stimulation for babies' development. Statistically significant improvements have been shown in babies' IQ, language abilities, musical/creative abilities, attention spans, sleep patterns, and early motor skills from stimulation provided at the right times and methods. Surprisingly, these benefits increased over the first 6 years of life rather than diminishing after birth. Bonding and love between parent and baby were reported as even greater benefits than developmental advantages. The document describes how parents were able to communicate with babies through touch patterns before birth, strengthening bonding.
Health Literacy design and Plain Language Writing of a Guide to Baby's Care for American Academy of Pediatrics. Winner of Silver Medal at the NHI Award 2010.
http://www.langsolinc.com/our-services/plain-language-and-health-literacy/
The document discusses fertility tracking and ovulation calculators. It includes responses to questions from several individuals about tracking irregular periods, the accuracy of online calculators, signs of pregnancy shortly after sex, and ways to determine ovulation through cervical fluid monitoring and basal body temperature tracking. Recommendations include using ovulation predictor kits, fertility tracking apps, and consulting with a doctor if experiencing unusual symptoms.
The document discusses preparing for childbirth using "The Pink Kit Method for birthing better". It encourages expecting mothers to reflect on their beliefs, experiences, and desires for birth. It emphasizes that all women share a universal human body and learning natural skills from The Pink Kit can help a woman experience birth in whatever situation she finds herself, including potentially unplanned interventions. It suggests The Pink Kit provides skills for both mothers and their partners to work together to have a more positive birth experience through relaxation and coping techniques.
If you are planning on having a family you can have a pregnancy, girl or boy, as you choose. There are thousands of people already controlling the gender of their baby.
Are you looking for a way to make your pregnancy gender specific? Well there are already thousands of people already ensuring what gender of baby they have..
Are you desperate to have a boy the next time you conceive? Well there are ways you can make it happen. There are certain techniques you can use to plan on how to have a boy.
Are you desperate to have a girl next time? That was the same thing I was hoping for, yet I made it happen.
Selecting the gender of your baby is possible if you follow the correct techniques.
Planning a baby? do you want boy girl or do you not care which it is. Maybe you are desperate for a son or daughter this time, and there are ways to choose the gender of the baby you want to conceive.
After having two sons, the speaker wanted to have a daughter and researched ways to increase the odds of conceiving a girl. She found a program called "Prince or Princess" that provides guidance on diet, fertility cycles, and calculating ovulation dates to sway the chances of conceiving a boy or girl. The program claims to have success stories but warns that nature ultimately determines the baby's sex and one must love the child regardless. It directs readers to a website with more information on increasing the odds of the desired baby's gender.
After having two sons, the speaker wanted to have a daughter and researched ways to increase the odds of conceiving a girl. She found a program called "Prince or Princess" that provided an easy-to-follow plan for selecting a baby's gender through diet, fertility awareness, and conception timing. The program claimed to avoid mistakes made by 87% of parents and explain factors like a woman's cycle and diet that could influence whether a baby is a boy or girl. However, the speaker notes that nature may override any planning or efforts to predict a baby's sex.
After having two sons, the speaker wanted to have a daughter and researched ways to increase the odds of conceiving a girl. She found a program called "Prince or Princess" that provides guidance on diet, fertility cycles, and calculating ovulation to sway the chances of conceiving a boy or girl. The program claims to have success stories but warns that nature ultimately determines the baby's sex and one must love the child regardless. It directs readers to a website for more information on increasing their chances of a daughter.
After having two sons, the speaker wanted to have a daughter and research ways to increase the odds of conceiving a girl. She spent 11 months researching methods to select a baby's gender and found the "Prince or Princess" program that consolidated different factors like diet, fertility cycle, and ovulation timing into an easy-to-follow plan. The program claims to show parents how to conceive a boy or girl by avoiding common mistakes and providing guidance, but warns that nature can override any plans.
After having two sons, the speaker wanted to have a daughter and researched ways to increase the odds of conceiving a girl. She found a program called "Prince or Princess" that provided an easy-to-follow plan for choosing a baby's gender through diet, fertility awareness, and conception timing. The program claimed to avoid mistakes made by 87% of parents and explain factors like a woman's cycle and diet that could sway the chances. However, the speaker notes that nature may override any plans and the baby should be loved regardless of its sex.
After having two sons, the speaker wanted to have a daughter and researched ways to increase the odds of conceiving a girl. She found a program called "Prince or Princess" that provides guidance on diet, fertility cycles, and calculating ovulation dates to sway the chances of conceiving a boy or girl. The program claims to have success stories but warns that nature ultimately determines the baby's sex and one must love the child regardless. It directs readers to a website for more information on increasing their chances of a daughter.
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Storyboard on Acne-Innovative Learning-M. pharm. (2nd sem.) CosmeticsMuskanShingari
Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells. It typically manifests as pimples, blackheads, or whiteheads, often on the face, chest, shoulders, or back. Acne can range from mild to severe and may cause emotional distress and scarring in some cases.
**Causes:**
1. **Excess Oil Production:** Hormonal changes during adolescence or certain times in adulthood can increase sebum (oil) production, leading to clogged pores.
2. **Clogged Pores:** When dead skin cells and oil block hair follicles, bacteria (usually Propionibacterium acnes) can thrive, causing inflammation and acne lesions.
3. **Hormonal Factors:** Fluctuations in hormone levels, such as during puberty, menstrual cycles, pregnancy, or certain medical conditions, can contribute to acne.
4. **Genetics:** A family history of acne can increase the likelihood of developing the condition.
**Types of Acne:**
- **Whiteheads:** Closed plugged pores.
- **Blackheads:** Open plugged pores with a dark surface.
- **Papules:** Small red, tender bumps.
- **Pustules:** Pimples with pus at their tips.
- **Nodules:** Large, solid, painful lumps beneath the surface.
- **Cysts:** Painful, pus-filled lumps beneath the surface that can cause scarring.
**Treatment:**
Treatment depends on the severity and type of acne but may include:
- **Topical Treatments:** Such as benzoyl peroxide, salicylic acid, or retinoids to reduce bacteria and unclog pores.
- **Oral Medications:** Antibiotics or oral contraceptives for hormonal acne.
- **Procedures:** Such as chemical peels, extraction of comedones, or light therapy for more severe cases.
**Prevention and Management:**
- **Cleanse:** Regularly wash skin with a gentle cleanser.
- **Moisturize:** Use non-comedogenic moisturizers to keep skin hydrated without clogging pores.
- **Avoid Irritants:** Such as harsh cosmetics or excessive scrubbing.
- **Sun Protection:** Use sunscreen to prevent exacerbation of acne scars and inflammation.
Acne treatment can take time, and consistency in skincare routines and treatments is crucial. Consulting a dermatologist can help tailor a treatment plan that suits individual needs and reduces the risk of scarring or long-term skin damage.
Dr. Tan's Balance Method.pdf (From Academy of Oriental Medicine at Austin)GeorgeKieling1
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Academy of Oriental Medicine at Austin
Academy of Oriental Medicine at Austin
Academy of Oriental Medicine at Austin
About AOMA: The Academy of Oriental Medicine at Austin offers a masters-level graduate program in acupuncture and Oriental medicine, preparing its students for careers as skilled, professional practitioners. AOMA is known for its internationally recognized faculty, award-winning student clinical internship program, and herbal medicine program. Since its founding in 1993, AOMA has grown rapidly in size and reputation, drawing students from around the nation and faculty from around the world. AOMA also conducts more than 20,000 patient visits annually in its student and professional clinics. AOMA collaborates with Western healthcare institutions including the Seton Family of Hospitals, and gives back to the community through partnerships with nonprofit organizations and by providing free and reduced price treatments to people who cannot afford them. The Academy of Oriental Medicine at Austin is located at 2700 West Anderson Lane. AOMA also serves patients and retail customers at its south Austin location, 4701 West Gate Blvd. For more information see www.aoma.edu or call 512-492-303434.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
Storyboard on Skin- Innovative Learning (M-pharm) 2nd sem. (Cosmetics)MuskanShingari
Skin is the largest organ of the human body, serving crucial functions that include protection, sensation, regulation, and synthesis. Structurally, it consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous layer).
1. **Epidermis**: The outermost layer primarily composed of epithelial cells called keratinocytes. It provides a protective barrier against environmental factors, pathogens, and UV radiation.
2. **Dermis**: Located beneath the epidermis, the dermis contains connective tissue, blood vessels, hair follicles, and sweat glands. It plays a vital role in supporting and nourishing the epidermis, regulating body temperature, and housing sensory receptors for touch, pressure, temperature, and pain.
3. **Hypodermis**: Also known as the subcutaneous layer, it consists of fat and connective tissue that anchors the skin to underlying structures like muscles and bones. It provides insulation, cushioning, and energy storage.
Skin performs essential functions such as regulating body temperature through sweat production and blood flow control, synthesizing vitamin D when exposed to sunlight, and serving as a sensory interface with the external environment.
Maintaining skin health is crucial for overall well-being, involving proper hygiene, hydration, protection from sun exposure, and avoiding harmful substances. Skin conditions and diseases range from minor irritations to chronic disorders, emphasizing the importance of regular care and medical attention when needed.
Storyboard on Skin- Innovative Learning (M-pharm) 2nd sem. (Cosmetics)
Baby predictor gender
1. Choosing The Gender of Your Baby I know the title of this presentation could seem a bit controversial, but let me explain I had always planned on having 3 children and one of them I wanted to be a girl. After giving birth to 2 lovely sons I knew that I only had one chance left to have a little girl.
2. Up to this point I had always thought that trying to select the sex of your baby was not wrong but I felt the surprise of what sex your baby is was all part of the wonderful experience of bringing a baby in to the world After having 2 boys I realised that trying to plan the gender of your baby is not such a controversial subject as I first though. So how do you go about choosing the gender of your baby?
3. The Search Begins Being in the medical field I realised that selecting the gender of your baby is not all cut and dried. I also realised that to turn the odds in my favour to have a little girl I would need to do a lot of research. That's when the search began. I spent months trawling the internet and medical papers for proof that I could choose my baby's gender.
4. Success After nearly 11 months of research I did realise that it is possible to increase the odds on what sex your baby is. The problem was that there were so many different aspects to it that you would need to be able to pull it all together in an easy to apply and follow program. I then stumbled on to something that really stopped me in my tracks.
5. I found that someone had already done all the hard work and put all the different aspects in to one simple program to follow. When I first read the program it was like the ABC of choosing the gender of your baby. Warning : I need to make one thing perfectly clear to anyone that is looking to try and have a baby and predict the sex that baby will be. You have to make sure that you are absolutely certain in your own mind that you will still love that baby regardless of what sex it is. There is one thing that can take all the planning and hard work you put in to this, and throw it out of the window, and that is Mother Nature!
6.
7. How conception works and the factors affecting conception of a baby girl or boy
8. The diet you need to increase your chances of conceiving either a boy or girl
9. Information on your fertility cycle and how to increase your fertility.
10. How to calculate your ovulation date and use this to determine the gender of your baby