This document provides an overview of financial management and short-term financing options. It begins with learning objectives about the role of financial managers, the financial planning process, and sources of short-term and long-term financing. It then discusses key needs for operational funds in firms and different types of short-term financing available, including trade credit, promissory notes, and loans from commercial banks.
This document provides an overview of key concepts in human resource management, including:
1) It outlines 10 learning objectives that cover topics like human resource planning, recruitment, selection, training, performance appraisal, compensation, and benefits.
2) It describes the six steps in the selection process and notes common mistakes job applicants make.
3) It explains that performance appraisals are used to evaluate employee performance against standards and make decisions about promotions, compensation, training or termination. The six steps in performance appraisals are also outlined.
This document provides an overview of structuring organizations for today's challenges. It discusses various organizational theories and models, including Fayol's and Weber's principles of bureaucracy, centralization vs decentralization, spans of control, departmentalization, and different organizational structures like line, line-and-staff, matrix, and cross-functional teams. The document also covers topics like virtual corporations, outsourcing, adapting to change, and the impact of technology on organizations.
This document provides an overview of Chapter 10 from a McGraw-Hill textbook on motivating employees. It includes learning objectives on motivation theories, key figures like Taylor and Maslow, and strategies for motivating employees. Case studies and examples are provided throughout to illustrate motivation concepts. The chapter examines intrinsic and extrinsic rewards, scientific management, the Hawthorne studies, Maslow's hierarchy of needs, Herzberg's two-factor theory, McGregor's Theory X and Y, goal-setting theory, and strategies for enriching jobs and communicating with employees.
This document summarizes key concepts about multinational enterprises (MNEs) from a textbook on international business. It discusses the characteristics and strategic management of MNEs. A central framework is the firm-specific advantages/country-specific advantages (FSA/CSA) matrix, which examines a firm's competitiveness based on its unique capabilities and advantages in different country markets. The document argues that while globalization has increased, strong regional barriers remain, and the world economy is not as flat as some claim due to challenges of operating across different regions.
Capitalising on Complexity - Insights from the Global CEO StudyThink Ethnic
Most CEOs doubt their ability to manage rapidly escalating complexity in today's volatile and uncertain global environment. However, some organizations called "Standouts" have consistently performed well financially over the past five years despite increased complexity. Standouts likely mitigate complexity and convert it into opportunity through new leadership styles, better understanding of customers, and flexible organizational structures. However, more investigation is needed to understand how Standouts are adapting to thrive in today's complex world.
This document discusses multinational enterprises (MNEs). It defines an MNE as a company headquartered in one country but operating in other countries. MNE affiliates must respond to various environmental forces and draw from common resources. The document then outlines the internationalization process that companies typically go through, beginning with exporting and licensing before establishing wholly owned subsidiaries. Finally, it discusses strategic management of MNEs, including analyzing internal/external environments and formulating objectives and plans to implement across affiliates.
This document discusses organizational structures for multinational enterprises. It begins by introducing the relationship between organizational structure and strategic positioning based on the FSA and CSA frameworks. It then outlines early organizational structures like export departments and subsidiaries that firms use when first expanding internationally. As firms grow globally, they adopt more complex structures like the international division, global product, area, functional, and matrix structures. The document also discusses mixed, transnational network structures and factors that influence centralization vs. decentralization of decision making in multinational operations.
Us Talent Managing Talentina Turbulent Economy Part3Achyut Menon "AK"
Deloitte report tracks the way business leaders were shifting their talent priorities and strategies to meet the challenges of today’s economy and their plans to clear the hurdles to economic recovery.
This document provides an overview of key concepts in human resource management, including:
1) It outlines 10 learning objectives that cover topics like human resource planning, recruitment, selection, training, performance appraisal, compensation, and benefits.
2) It describes the six steps in the selection process and notes common mistakes job applicants make.
3) It explains that performance appraisals are used to evaluate employee performance against standards and make decisions about promotions, compensation, training or termination. The six steps in performance appraisals are also outlined.
This document provides an overview of structuring organizations for today's challenges. It discusses various organizational theories and models, including Fayol's and Weber's principles of bureaucracy, centralization vs decentralization, spans of control, departmentalization, and different organizational structures like line, line-and-staff, matrix, and cross-functional teams. The document also covers topics like virtual corporations, outsourcing, adapting to change, and the impact of technology on organizations.
This document provides an overview of Chapter 10 from a McGraw-Hill textbook on motivating employees. It includes learning objectives on motivation theories, key figures like Taylor and Maslow, and strategies for motivating employees. Case studies and examples are provided throughout to illustrate motivation concepts. The chapter examines intrinsic and extrinsic rewards, scientific management, the Hawthorne studies, Maslow's hierarchy of needs, Herzberg's two-factor theory, McGregor's Theory X and Y, goal-setting theory, and strategies for enriching jobs and communicating with employees.
This document summarizes key concepts about multinational enterprises (MNEs) from a textbook on international business. It discusses the characteristics and strategic management of MNEs. A central framework is the firm-specific advantages/country-specific advantages (FSA/CSA) matrix, which examines a firm's competitiveness based on its unique capabilities and advantages in different country markets. The document argues that while globalization has increased, strong regional barriers remain, and the world economy is not as flat as some claim due to challenges of operating across different regions.
Capitalising on Complexity - Insights from the Global CEO StudyThink Ethnic
Most CEOs doubt their ability to manage rapidly escalating complexity in today's volatile and uncertain global environment. However, some organizations called "Standouts" have consistently performed well financially over the past five years despite increased complexity. Standouts likely mitigate complexity and convert it into opportunity through new leadership styles, better understanding of customers, and flexible organizational structures. However, more investigation is needed to understand how Standouts are adapting to thrive in today's complex world.
This document discusses multinational enterprises (MNEs). It defines an MNE as a company headquartered in one country but operating in other countries. MNE affiliates must respond to various environmental forces and draw from common resources. The document then outlines the internationalization process that companies typically go through, beginning with exporting and licensing before establishing wholly owned subsidiaries. Finally, it discusses strategic management of MNEs, including analyzing internal/external environments and formulating objectives and plans to implement across affiliates.
This document discusses organizational structures for multinational enterprises. It begins by introducing the relationship between organizational structure and strategic positioning based on the FSA and CSA frameworks. It then outlines early organizational structures like export departments and subsidiaries that firms use when first expanding internationally. As firms grow globally, they adopt more complex structures like the international division, global product, area, functional, and matrix structures. The document also discusses mixed, transnational network structures and factors that influence centralization vs. decentralization of decision making in multinational operations.
Us Talent Managing Talentina Turbulent Economy Part3Achyut Menon "AK"
Deloitte report tracks the way business leaders were shifting their talent priorities and strategies to meet the challenges of today’s economy and their plans to clear the hurdles to economic recovery.
Glasspray Corporation, a small manufacturer experiencing rapid sales growth, is facing working capital issues as its current assets are not keeping pace with rising current liabilities. The company president laments that continuing sales increases could lead the company into bankruptcy if it cannot better manage its working capital position through techniques like accounts receivable management and short-term financing options.
ExtraFunds is seeking $1 million in investment capital to fund operating expenses like hiring more call center employees and marketing. Investors will receive 12% annual interest on promissory notes. ExtraFunds services loans for online lenders, providing marketing, underwriting, and collections. It has made over 41,000 loans totaling $14 million. ExtraFunds projects continued growth over the next 3 years by increasing marketing and call center staff.
ExtraFunds is a proven servicer in the short-term online lending marketplace. ExtraFunds is currently seeking to expand its operations by raising capital via Crowdfunder. For more details about the offering, visit www.crowdfunder.com/extrafunds.
The document discusses the roles and responsibilities of finance and financial managers. It describes what financial management entails, including preparing budgets, analyzing cash flows, and planning for expenditures. It also lists some of the main concerns of financial managers, such as consumer demand, interest rates, and regulatory issues.
The document discusses various concepts related to strategic financial management. It covers:
1. The role of strategic management in helping organizations formulate better strategies through a systematic approach.
2. Key terms related to finance like mortgages, loans, bonds, and the effects of noise trading in markets.
3. The benefits of strategic financial management, including improved sales, profits, productivity, and understanding of competitors.
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This proposed change raises ethical concerns that should be carefully considered. While improving cash flow is important, ensuring adequate medical supplies could be a higher priority to protect patient well-being. All stakeholders should be involved in thoughtful discussion before making changes that could potentially compromise care.
This document provides an overview of financial management concepts from a business textbook. It discusses the importance of financial management, identifying short- and long-term financial needs, and summarizing the financial planning process. Short-term financing options like trade credit, promissory notes, and bank loans are examined. Long-term financing through stock sales and retained earnings is also summarized. The document aims to teach students key aspects of obtaining and utilizing financing.
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Working Capital and Sources of Short-Term FundAvone Lumanao
The document discusses the financing policy and sources of working capital for firms. It defines working capital and explains why it is important for companies. It identifies three approaches to financing working capital: conservative, maturity matching, and aggressive. It also discusses how Philippine firms finance working capital and the sources of short-term funds available, including bank loans, trade financing, and receivable factoring. The key aspects are determining the appropriate financing strategy for a firm's working capital needs and the various short-term sources available, particularly bank loans.
612
Chapter
Statement of
Cash Flows
After studying this chapter, you should be
able to:
1 Indicate the usefulness of the statement
of cash flows.
2 Distinguish among operating, investing,
and financing activities.
3 Prepare a statement of cash flows using
the indirect method.
4 Analyze the statement of cash flows.
S T U D Y O B J E C T I V E S
Feature Story
The Navigator✓
13
GOT CASH?
In today’s environment, companies must be ready to respond to changes
quickly in order to survive and thrive. They need to produce new products
and expand into new markets continually. To do this takes cash—lots and
lots of cash. Keeping lots of cash available is a real challenge for a young
company. It requires careful cash management and attention to cash flow.
One company that managed cash successfully in its early years was
Microsoft (www.microsoft.com). During those years the company paid much
of its payroll with stock options (rights to purchase company stock in the
future at a given price) instead of cash. This strategy conserved cash, and
turned more than a thousand of its employees into millionaires during the
company’s first 20 years of business.
In recent years Microsoft has had a different kind of cash problem. Now that
it has reached a more “mature” stage in life, it generates so much cash—
roughly $1 billion per month—that it cannot always figure out what to do
with it. By 2004 Microsoft had accumulated $60 billion.
Scan Study Objectives ■
Read Feature Story ■
Read Preview ■
Read text and answer
p. 617 ■ p. 625 ■ p. 628 ■ p. 632 ■
Work Comprehensive p. 634 ■
Review Summary of Study Objectives ■
Work Comprehensive p. 648 ■
Answer Self-Study Questions ■
Complete Assignments ■
The Navigator✓
Do it!
Do it!
Do it!
JWCL165_c13_612-673.qxd 8/13/09 11:15 AM Page 612
613
The company said it was accumu-
lating cash to invest in new oppor-
tunities, buy other companies, and
pay off pending lawsuits. But for
years, the federal government has
blocked attempts by Microsoft to
buy anything other than small firms
because it feared that purchase of
a large firm would only increase
Microsoft’s monopolistic position.
In addition, even the largest esti-
mates of Microsoft’s legal obligations
related to pending lawsuits would use up only about $6 billion in cash.
Microsoft’s stockholders have complained for years that holding all this cash
was putting a drag on the company’s profitability. Why? Because Microsoft
had the cash invested in very low-yielding government securities. Stockhold-
ers felt that the company either should find new investment projects that
would bring higher returns, or return some of the cash to stockholders.
Finally, in July 2004 Microsoft announced a plan to return cash to stockhold-
ers, by paying a special one-time $32 billion dividend in December 2004.
This special dividend was so large that, according to the U.S. Commerce
Department, it caused total personal income in the United Stat.
The document discusses the uses and purpose of cash flow statements, which classify cash flows into operating, investing and financing activities to assess a firm's ability to generate cash flows, meet obligations, and need for external financing. It also covers how cash flow statements help investors and the different types of audits including statutory, non-statutory, internal, external, interim and continuous audits.
Need capital to start, grow and manage your business, we provide loans in the form of short term loans and long term loans, check your ability to get a loan by bank loan rating and credit score check. Get complete information about the Syndication & Funding right from Term Loans to Unsecured Loans and the Process.
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This document provides instructions for a signature assignment for a finance course. Students are asked to create a 15-slide PowerPoint presentation proposing an initial $500,000 funding request to start a new business. The presentation must include slides on the business overview, industry, marketing plan, financial projections, funding needs, expansion plans, and references. Students will present their proposal to the class for feedback and evaluation.
This document provides instructions for a signature assignment for a finance course. Students are asked to create a 15-slide PowerPoint presentation proposing an initial $500,000 funding request to start a new business. The presentation must include slides on the business overview, industry, marketing plan, financial projections, funding needs, expansion plans, and references. Students will present their proposal to the class for feedback and evaluation.
Managing Business Debts " A book to enlargen your horizon in managing busines...lewisjunior142
This document provides an overview of business debt, including its definition, types, advantages and disadvantages, management strategies, and how businesses can obtain debt. It discusses short-term and long-term debt, secured vs unsecured loans, and how debt can help businesses grow but also poses risks if not managed properly. The document also examines debt ratios, debt capacity, and includes case studies of how businesses have successfully used and paid off loans.
The document discusses the drivers and pressures for organizational change. It identifies that change comes from both external environmental pressures such as competition, regulations and technological changes as well as internal pressures like growth, leadership changes, and politics. Some of the key external pressures mentioned are globalization, hypercompetition, and reputation concerns. The document also examines why organizations may not change in response to environmental pressures or after crises, citing factors such as organizational learning difficulties and defensive priorities over innovation.
This document discusses evolutionary developmental biology and how changes in development can lead to evolutionary changes. It provides examples of modularity and molecular parsimony which help explain this. Modularity means parts of the body and DNA can develop differently. Molecular parsimony means organisms share developmental toolkit genes. The document then discusses specific examples like stickleback fish pelvic spines being due to different Pitx1 expression, and Darwin's finches having beak shape variations due to differing Bmp4 and Calmodulin expression levels. Mechanisms of evolutionary change include changes in location, timing, amount, or kind of gene expression.
Glasspray Corporation, a small manufacturer experiencing rapid sales growth, is facing working capital issues as its current assets are not keeping pace with rising current liabilities. The company president laments that continuing sales increases could lead the company into bankruptcy if it cannot better manage its working capital position through techniques like accounts receivable management and short-term financing options.
ExtraFunds is seeking $1 million in investment capital to fund operating expenses like hiring more call center employees and marketing. Investors will receive 12% annual interest on promissory notes. ExtraFunds services loans for online lenders, providing marketing, underwriting, and collections. It has made over 41,000 loans totaling $14 million. ExtraFunds projects continued growth over the next 3 years by increasing marketing and call center staff.
ExtraFunds is a proven servicer in the short-term online lending marketplace. ExtraFunds is currently seeking to expand its operations by raising capital via Crowdfunder. For more details about the offering, visit www.crowdfunder.com/extrafunds.
The document discusses the roles and responsibilities of finance and financial managers. It describes what financial management entails, including preparing budgets, analyzing cash flows, and planning for expenditures. It also lists some of the main concerns of financial managers, such as consumer demand, interest rates, and regulatory issues.
The document discusses various concepts related to strategic financial management. It covers:
1. The role of strategic management in helping organizations formulate better strategies through a systematic approach.
2. Key terms related to finance like mortgages, loans, bonds, and the effects of noise trading in markets.
3. The benefits of strategic financial management, including improved sales, profits, productivity, and understanding of competitors.
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This proposed change raises ethical concerns that should be carefully considered. While improving cash flow is important, ensuring adequate medical supplies could be a higher priority to protect patient well-being. All stakeholders should be involved in thoughtful discussion before making changes that could potentially compromise care.
This document provides an overview of financial management concepts from a business textbook. It discusses the importance of financial management, identifying short- and long-term financial needs, and summarizing the financial planning process. Short-term financing options like trade credit, promissory notes, and bank loans are examined. Long-term financing through stock sales and retained earnings is also summarized. The document aims to teach students key aspects of obtaining and utilizing financing.
fin 571 week 6 assignment start-up company signature assignment new,uop fin 571,fin 571,uop fin 571 week 6 tutorial,fin 571 week 6 assignment,uop fin 571 week 6 help
Working Capital and Sources of Short-Term FundAvone Lumanao
The document discusses the financing policy and sources of working capital for firms. It defines working capital and explains why it is important for companies. It identifies three approaches to financing working capital: conservative, maturity matching, and aggressive. It also discusses how Philippine firms finance working capital and the sources of short-term funds available, including bank loans, trade financing, and receivable factoring. The key aspects are determining the appropriate financing strategy for a firm's working capital needs and the various short-term sources available, particularly bank loans.
612
Chapter
Statement of
Cash Flows
After studying this chapter, you should be
able to:
1 Indicate the usefulness of the statement
of cash flows.
2 Distinguish among operating, investing,
and financing activities.
3 Prepare a statement of cash flows using
the indirect method.
4 Analyze the statement of cash flows.
S T U D Y O B J E C T I V E S
Feature Story
The Navigator✓
13
GOT CASH?
In today’s environment, companies must be ready to respond to changes
quickly in order to survive and thrive. They need to produce new products
and expand into new markets continually. To do this takes cash—lots and
lots of cash. Keeping lots of cash available is a real challenge for a young
company. It requires careful cash management and attention to cash flow.
One company that managed cash successfully in its early years was
Microsoft (www.microsoft.com). During those years the company paid much
of its payroll with stock options (rights to purchase company stock in the
future at a given price) instead of cash. This strategy conserved cash, and
turned more than a thousand of its employees into millionaires during the
company’s first 20 years of business.
In recent years Microsoft has had a different kind of cash problem. Now that
it has reached a more “mature” stage in life, it generates so much cash—
roughly $1 billion per month—that it cannot always figure out what to do
with it. By 2004 Microsoft had accumulated $60 billion.
Scan Study Objectives ■
Read Feature Story ■
Read Preview ■
Read text and answer
p. 617 ■ p. 625 ■ p. 628 ■ p. 632 ■
Work Comprehensive p. 634 ■
Review Summary of Study Objectives ■
Work Comprehensive p. 648 ■
Answer Self-Study Questions ■
Complete Assignments ■
The Navigator✓
Do it!
Do it!
Do it!
JWCL165_c13_612-673.qxd 8/13/09 11:15 AM Page 612
613
The company said it was accumu-
lating cash to invest in new oppor-
tunities, buy other companies, and
pay off pending lawsuits. But for
years, the federal government has
blocked attempts by Microsoft to
buy anything other than small firms
because it feared that purchase of
a large firm would only increase
Microsoft’s monopolistic position.
In addition, even the largest esti-
mates of Microsoft’s legal obligations
related to pending lawsuits would use up only about $6 billion in cash.
Microsoft’s stockholders have complained for years that holding all this cash
was putting a drag on the company’s profitability. Why? Because Microsoft
had the cash invested in very low-yielding government securities. Stockhold-
ers felt that the company either should find new investment projects that
would bring higher returns, or return some of the cash to stockholders.
Finally, in July 2004 Microsoft announced a plan to return cash to stockhold-
ers, by paying a special one-time $32 billion dividend in December 2004.
This special dividend was so large that, according to the U.S. Commerce
Department, it caused total personal income in the United Stat.
The document discusses the uses and purpose of cash flow statements, which classify cash flows into operating, investing and financing activities to assess a firm's ability to generate cash flows, meet obligations, and need for external financing. It also covers how cash flow statements help investors and the different types of audits including statutory, non-statutory, internal, external, interim and continuous audits.
Need capital to start, grow and manage your business, we provide loans in the form of short term loans and long term loans, check your ability to get a loan by bank loan rating and credit score check. Get complete information about the Syndication & Funding right from Term Loans to Unsecured Loans and the Process.
fin 571 week 6 assignment start-up company signature assignment new,uop fin 571,fin 571,uop fin 571 week 6 tutorial,fin 571 week 6 assignment,uop fin 571 week 6 help
This document provides instructions for a signature assignment for a finance course. Students are asked to create a 15-slide PowerPoint presentation proposing an initial $500,000 funding request to start a new business. The presentation must include slides on the business overview, industry, marketing plan, financial projections, funding needs, expansion plans, and references. Students will present their proposal to the class for feedback and evaluation.
This document provides instructions for a signature assignment for a finance course. Students are asked to create a 15-slide PowerPoint presentation proposing an initial $500,000 funding request to start a new business. The presentation must include slides on the business overview, industry, marketing plan, financial projections, funding needs, expansion plans, and references. Students will present their proposal to the class for feedback and evaluation.
Managing Business Debts " A book to enlargen your horizon in managing busines...lewisjunior142
This document provides an overview of business debt, including its definition, types, advantages and disadvantages, management strategies, and how businesses can obtain debt. It discusses short-term and long-term debt, secured vs unsecured loans, and how debt can help businesses grow but also poses risks if not managed properly. The document also examines debt ratios, debt capacity, and includes case studies of how businesses have successfully used and paid off loans.
Similar to BA 100 Chapter 16 PowerPoint - Week 7 (20)
The document discusses the drivers and pressures for organizational change. It identifies that change comes from both external environmental pressures such as competition, regulations and technological changes as well as internal pressures like growth, leadership changes, and politics. Some of the key external pressures mentioned are globalization, hypercompetition, and reputation concerns. The document also examines why organizations may not change in response to environmental pressures or after crises, citing factors such as organizational learning difficulties and defensive priorities over innovation.
This document discusses evolutionary developmental biology and how changes in development can lead to evolutionary changes. It provides examples of modularity and molecular parsimony which help explain this. Modularity means parts of the body and DNA can develop differently. Molecular parsimony means organisms share developmental toolkit genes. The document then discusses specific examples like stickleback fish pelvic spines being due to different Pitx1 expression, and Darwin's finches having beak shape variations due to differing Bmp4 and Calmodulin expression levels. Mechanisms of evolutionary change include changes in location, timing, amount, or kind of gene expression.
Developmental plasticity allows an organism's phenotype to change in response to environmental conditions during development. There are two main types of phenotypic plasticity: reaction norms, where the environment determines the phenotype from a continuum of genetic possibilities, and polyphenisms, where discrete alternative phenotypes are produced. Examples include caterpillars changing appearance to match plant growth stages, frogs hatching early in response to vibrations, and temperature determining sex in crocodiles. Stressors like water levels can also influence development, as seen in spadefoot toads. Symbiotic relationships between organisms, like nitrogen-fixing bacteria in plant roots, are important to development and often involve vertical transmission from parents. Gut bacteria are also necessary for
This document discusses several genetic and environmental factors that can influence human development. Genetic factors like pleiotropy and mosaicism can result in syndromes with multiple abnormalities. The same genetic mutation can also produce different phenotypes depending on gene interactions. Environmental teratogens during critical periods of embryonic development can irreversibly damage organ formation, with alcohol, retinoic acid, and endocrine disruptors like bisphenol A and atrazine posing particular risks like fetal alcohol syndrome, cleft palate, lower sperm counts, and cancer. Both genetic and environmental heterogeneity contribute to the complexity of human development.
The endoderm forms the epithelial lining of the digestive and respiratory systems. It gives rise to tissues like the notochord, heart, blood vessels, and parts of the mesoderm. The endoderm comes from two sources - the definitive endoderm and the visceral endoderm. The transcription factor Sox17 marks and regulates the formation of the endoderm. The endoderm lines tubes in the body and gives rise to organs like the liver, pancreas, lungs and digestive system through the formation of buds and pouches along the foregut.
The document summarizes the development of the intermediate mesoderm and lateral plate mesoderm. The intermediate mesoderm forms the urogenital system including the kidneys, ureters, ovaries, fallopian tubes, testes and vas deferens. Kidney development occurs through the pronephros, mesonephros and metanephros stages. The lateral plate mesoderm splits into somatic and splanchnic layers and forms the heart through the merging of cardiac progenitor cells from both sides of the embryo. The heart tube loops to the right to begin resembling the four-chambered adult heart.
The paraxial mesoderm lies just lateral to the notochord and gives rise to vertebrae, skeletal muscles, and skin connective tissue. It is divided into somites which then form dermomyotomes and sclerotomes. Dermomyotomes develop into dermatomes that make dermis and myotomes that form back, rib, and body wall muscles. Sclerotomes form the vertebrae and rib cage. Somitogenesis occurs through a clock-wavefront model where somites sequentially segment from cranial to caudal regions under the influence of signaling molecules like retinoic acid and FGF.
The document summarizes ectodermal placodes and the epidermis. It discusses how placodes give rise to sensory structures like the eye lens, inner ear, and nose. It describes the different cranial placodes that form sensory tissues and nerves, including the anterior placodes that form the pituitary gland and eye lens. The intermediate placodes form nerves involved in sensation of the face and hearing/balance. The epidermis derives from surface ectoderm under the influence of BMPs and forms the protective outer layer of skin and its appendages like hair, sweat glands, and teeth.
- The neural plate transforms into a neural tube through a process called neurulation regulated by proteins like BMP and transcription factors like Sox1, 2, and 3.
- Primary neurulation involves the elongation, bending, and convergence of the neural folds before their closure at the midline to form the neural tube. Key regulation events involve hinge points at the midline and dorsolateral edges.
- Neural tube defects can occur if closure fails, as in spina bifida where the posterior neuropore remains open, preventing proper spinal cord development.
Mammalian development begins with fertilization and cleavage of the egg. The egg develops membranes that allow development outside of water. In mammals, the placenta exchanges gases and nutrients between the embryo and mother. Cleavage is rotational, with zygotic genes activating later than other animals. Cells compact and the morula forms an inner cell mass and trophoblast cells. The trophoblast secretes fluid to form a blastocyst cavity. The inner cell mass forms the epiblast and hypoblast, which generate the embryo and extraembryonic tissues through gastrulation. Axis formation is guided by gradients of genes like HOX and left/right asymmetries are regulated by proteins including Nodal.
- Drosophila melanogaster is a useful model organism for studying development due to its short life cycle, fully sequenced genome, and ease of breeding.
- Early Drosophila development involves syncytial cleavage where nuclei divide without cell division, specifying the dorsal/ventral and anterior/posterior axes.
- Fertilization occurs when sperm enters an egg that has already begun specifying axes; maternal and paternal chromosomes remain separate during early divisions.
This document summarizes key patterns in animal development. It describes that animals undergo gastrulation where cells migrate to form germ layers and axes. Animals are categorized into 35 phyla based on features like germ layers, organ formation, and cleavage patterns. It describes that diploblastic animals have two germ layers while most are triploblastic with three germ layers. Triploblastic animals are further divided into protostomes and deuterostomes based on mouth formation. The document also provides examples of cleavage patterns in snails which are spirally arranged in either a dextral or sinistral pattern determined by maternal factors.
1) Sex determination in mammals is primarily determined by the XY sex determination system, with females having XX and males having XY. The SRY gene on the Y chromosome causes the development of testes.
2) The gonads are initially bipotential but develop into either ovaries or testes based on the sex chromosomes. Testes secrete AMH and testosterone to direct male development while ovaries secrete estrogens for female development.
3) Gametogenesis includes the process of meiosis which produces haploid gametes from diploid germ cells in the gonads. In females, oogenesis begins in the embryo but arrests until puberty while spermatogenesis only occurs at puberty in males.
Stem cells are unspecialized cells that can divide and differentiate into specialized cell types. There are several types of stem cells defined by their potency, including totipotent stem cells found in early embryos, pluripotent stem cells in the embryo, and multipotent adult stem cells. Stem cell regulation is controlled through extracellular signals from the stem cell niche and intracellular factors that influence gene expression and cell fate. Researchers have also induced pluripotency in adult cells by introducing genes that code for key transcription factors.
This document discusses cell-to-cell communication and how it allows for the development of specialized tissues and organs through three main mechanisms: cell adhering, cell shape changing, and cell signaling. It describes how cells interact at the cell membrane through various receptor and ligand proteins. These interactions can be homophilic or heterophilic, and occur through direct contact between neighboring cells (juxtacrine signaling) or over short distances (paracrine signaling). Differential adhesion and cadherins allow cells to sort themselves into tissues based on adhesion strengths. The extracellular matrix and integrins also influence cell communication and development.
Differential gene expression refers to the process where different genes are activated in different cell types, leading to cellular specialization. While all cells contain the full genome, only a small percentage of genes are expressed in each cell. Gene expression is regulated at multiple levels, including differential transcription, selective pre-mRNA processing, selective mRNA translation, and posttranslational protein modification. The most common mechanisms involve regulating transcription through epigenetic modifications of chromatin and the use of transcription factors.
The document summarizes key stages in animal development from fertilization through organogenesis. It begins with fertilization and cleavage, followed by gastrulation where the three germ layers (endoderm, mesoderm, ectoderm) are formed. During organogenesis, organs develop from the germ layers. Metamorphosis may also occur to transition organisms like frogs from immature to sexually mature forms. Examples are provided of developmental processes in frogs and other model organisms like fruit flies and plants. Cell behavior and patterning during these stages are also discussed.
The document discusses considerations for small businesses when hiring employees. It covers deciding when to hire an employee, defining job roles, writing job descriptions, attracting and evaluating candidates, selecting the right hire, training employees, rewarding and compensating employees, and managing ownership and dividends when there are family business partners involved. The key aspects of setting up an employee program for a small business are planning job roles, writing thorough job descriptions, developing fair hiring and review processes, providing training, and establishing clear compensation and ownership structures.
This document discusses various legal issues that small business owners should be aware of, including:
- Understanding the different types of laws (federal, state, local) that may apply to a small business.
- Hiring an experienced small business attorney to provide legal advice and represent the business as needed.
- Choosing an appropriate legal structure for the business, such as a sole proprietorship, partnership, corporation, or LLC.
- Protecting the business name as intellectual property and complying with regulations regarding contracts, liability, taxation and other legal matters.
This document discusses risk management and insurance for small businesses. It begins by defining risk for business owners and identifying common sources of risk such as financial investments, theft, nonpayment of debts, and natural disasters. It then examines risks related to a business's property, personnel, customers, and intangible property. The document provides strategies for managing these risks, such as developing policies and procedures, securing valuable assets, and obtaining different types of insurance. It concludes by discussing ways for businesses to share risk through joint ventures, industry groups, and government funding programs.
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
How to Fix the Import Error in the Odoo 17Celine George
An import error occurs when a program fails to import a module or library, disrupting its execution. In languages like Python, this issue arises when the specified module cannot be found or accessed, hindering the program's functionality. Resolving import errors is crucial for maintaining smooth software operation and uninterrupted development processes.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
Executive Directors Chat Leveraging AI for Diversity, Equity, and InclusionTechSoup
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
Walmart Business+ and Spark Good for Nonprofits.pdfTechSoup
"Learn about all the ways Walmart supports nonprofit organizations.
You will hear from Liz Willett, the Head of Nonprofits, and hear about what Walmart is doing to help nonprofits, including Walmart Business and Spark Good. Walmart Business+ is a new offer for nonprofits that offers discounts and also streamlines nonprofits order and expense tracking, saving time and money.
The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
Walmart Business + (https://business.walmart.com/plus) is a new shopping experience for nonprofits, schools, and local business customers that connects an exclusive online shopping experience to stores. Benefits include free delivery and shipping, a 'Spend Analytics” feature, special discounts, deals and tax-exempt shopping.
Special TechSoup offer for a free 180 days membership, and up to $150 in discounts on eligible orders.
Spark Good (walmart.com/sparkgood) is a charitable platform that enables nonprofits to receive donations directly from customers and associates.
Answers about how you can do more with Walmart!"
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
How to Make a Field Mandatory in Odoo 17Celine George
In Odoo, making a field required can be done through both Python code and XML views. When you set the required attribute to True in Python code, it makes the field required across all views where it's used. Conversely, when you set the required attribute in XML views, it makes the field required only in the context of that particular view.
How to Build a Module in Odoo 17 Using the Scaffold MethodCeline George
Odoo provides an option for creating a module by using a single line command. By using this command the user can make a whole structure of a module. It is very easy for a beginner to make a module. There is no need to make each file manually. This slide will show how to create a module using the scaffold method.
This presentation was provided by Steph Pollock of The American Psychological Association’s Journals Program, and Damita Snow, of The American Society of Civil Engineers (ASCE), for the initial session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session One: 'Setting Expectations: a DEIA Primer,' was held June 6, 2024.
See Learning Objective 1: Explain the responsibilities of financial managers.
The finance function is responsible for managing a scarce resource - capital.
See Learning Objective 1: Explain the responsibilities of financial managers.
See Learning Objective 1: Explain the responsibilities of financial managers.
This slide provides insight into the role of financial management.
One point that is critical to communicate to students, is that financial managers must understand accounting (and in fact many of them have backgrounds in accounting), but they are not accountants within the company. They are decision-makers and managers in the truest sense of the word.
You might want to work through each of the functions of the financial manager and make certain students see exactly what’s involved in such a job. Students often perk up when they hear that quite often next to the company CEO, the chief financial officer (CFO) is the highest paid person within an organization. It’s also a good time with this slide to reinforce exactly how the relationship between accounting and finance works. If students can catch on early, this chapter is easy for them to navigate.
See Learning Objective 1: Explain the responsibilities of financial managers.
This slide presents the positions a person in finance might hold.
Help students understand that there are a variety of positions a person in finance might strive to obtain.
Ask students: What are some of the functions/responsibilities of each of these positions? How are these positions alike? How might they be different?
See Learning Objective 1: Explain the responsibilities of financial managers.
See Learning Objective 1: Explain the responsibilities of financial managers.
This slide (based on Figure 16.1) gives the student a broad overview of what responsibilities financial managers have within a corporation. The CFOs responsibilities are rooted in the functions of “control” and “treasury.”
The control function has its basis in the budgeting process:
The budget represents the quantification of the goals and missions of the company as manifested by the resources required to attain those goals.
The budget becomes the scorecard by which the company as a whole is measured.
3. The other area of responsibility for CFOs is the treasury function.
Procurement of financial resources available to the company.
Ongoing communication with financial sources, investors, and debt holders who must be kept apprised of the firm’s financial performance.
Allocation of resources within the context of the company budget.
See Learning Objective 1: Explain the responsibilities of financial managers.
This slide highlights the things that worry financial managers.
Financial managers are required to wear many hats in the organization. While specific responsibilities of a CFO will vary between large and small companies, and public and closely held companies, the principles of control and treasury responsibilities transgress all boundaries.
The number of issues that financial managers face is one reason why they are so well compensated.
See Learning Objective 1: Explain the responsibilities of financial managers.
See Learning Objective 1: Explain the responsibilities of financial managers.
This slide highlights the top concerns of company CFOs in the macro economy.
The Chief Financial Officers of companies must concern themselves with a multitude of issues.
See Learning Objective 1: Explain the responsibilities of financial managers.
This slide highlights the top concerns of company CFOs within their own businesses.
The Chief Financial Officers of companies must concern themselves with a multitude of issues.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
Budgeting is critical for the organization to control expenses and to understand revenue expectations.
Think of a budget as a guidepost or a reference point for the organization’s managers.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
This slide is based on Figure 16.2.
The capital and cash budgets are part of the operating (master) budget.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
Financial controls also help reveal which specific accounts, departments and people are varying from the financial plan.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
This slide highlights the factors used in assessing financial control.
Financial control is used in conjunction with the firm’s budget to ensure the organization is meeting its commitments and goals.
Ask students: Why is it important for the CFO to maintain financial control?
The three finance functions are: financial planning, budgeting, and the establishment of financial control.
The three primary financial problems causing firms to fail are: undercapitalization, poor control of cash flow, and inadequate expense control.
Short-term forecasts attempt to project revenue, costs, and expenses for a period of one year or less, while long-term forecasts are for a period greater than one year.
A budget sets forth management’s expectations for revenues and becomes the organization’s primary guide for the financial operations as well as expected financial needs. The three types of budgets are: capital, cash, and operating.
See Learning Objective 3: Explain why firms need operating funds.
See Learning Objective 3: Explain why firms need operating funds.
The slide lists methods small businesses use to improve cash flow.
Lack of cash flow can impact a business of any size and may lead to the business shutting its doors.
It is critical that students understand cash is king for a business of any size.
See Learning Objective 2: Outline the financial planning process and explain the three key budgets in the financial plan.
See Learning Objective 3: Explain why firms need operating funds.
See Learning Objective 3: Explain why firms need operating funds.
See Learning Objective 3: Explain why firms need operating funds.
It is important for management to understand that they need capital for a variety of short-term and long-term situations.
Time value of money means money can grow over time through interest earned.
Providing credit to customers is often necessary to keep current customers happy and to attract new customers. The problem with selling on credit is that as much as 25 percent of the firm’s assets could be tied up in accounts receivable. This forces the business to use it own funds to pay for goods or services sold to customers who bought on credit.
To attract customers a firm must purchase inventory as well as invest in tangible long-term assets such as land, buildings, and equipment, or intangible assets such as patents, trademarks, and copyrights.
The primary difference between debt and equity financing is that debt must be repaid at maturity, while there is no obligation to repay equity financing. Interest must be paid on debt while the company is under no obligation to issue dividends on equity financing. The interest paid is tax deductible while dividends are not. Finally, debt holders do not have the right to vote on company matters as equity holders do.
See Learning Objective 4: Identify and describe different sources of short-term financing.
Trade credit is the most common form of financing. 2/10 net 30 means a firm can receive a 2% discount if the bill is paid within 10 days. If they choose not to take the discount, the net amount is due in 30 days.
See Learning Objective 4: Identify and describe different sources of short-term financing.
See Learning Objective 4: Identify and describe different sources of short-term financing.
See Learning Objective 4: Identify and describe different sources of short-term financing.
See Learning Objective 4: Identify and describe different sources of short-term financing.
See Learning Objective 4: Identify and describe different sources of short-term financing.
See Learning Objective 4: Identify and describe different sources of short-term financing.
The commercial paper market is an important source of funding for financially stable companies.
During the financial crisis which started in 2008, this important market completely shut down, forcing the Federal Reserve to step in and assist many companies with their short-term financing by purchasing their commercial paper.
See Learning Objective 4: Identify and describe different sources of short-term financing.
See Learning Objective 4: Identify and describe different sources of short-term financing.
This slide profiles some of the unique methods businesses can use to raise capital.
Trade credit and factoring are two of the oldest methods of raising capital. To start a discussion with students ask the advantages and disadvantages of using each of these methods.
Peer-to-peer lending involves individuals loaning money to other individuals or businesses thus bypassing traditional lending outlets.
For more information on this new method use loan statistics from www.lendingclub.com
See Learning Objective 4: Identify and describe different sources of short-term financing.
2/10 net 30 means a firm can receive a 2% discount if the bill is paid within 10 days. If they choose not to take the discount, the net amount is due in 30 days.
Trade credit is buying goods and services now and paying for them later, while a line of credit is a given amount of unsecured short term funds a bank will lend a business, provided the funds are readily available.
A secured loan requires collateral, while an unsecured loan doesn’t not.
Factoring is the process of sell accounts receivable for cash. Things to consider in establishing the discount rate are: age of the accounts receivable, the nature of the business, and the condition of the economy.
See Learning Objective 5: Identify and describe different sources of long-term financing.
See Learning Objective 5: Identify and describe different sources of long-term financing.
This slide highlights the 5 “C”s of credit that lenders use to make decisions.
It is essential that lenders make good decisions when deciding whether or not to loan capital to potential borrowers.
Go through each of the C’s and have students evaluate how important each one is. Are they equally important for the lenders to consider? Why or why not?
Ask students: Can you think of any other things the lenders should consider before loaning money? (Note: these do not have to be words that start with C.)
See Learning Objective 5: Identify and describe different sources of long-term financing.
In 2012, Middle Eastern nations spent less on foreign investments than they had in years. Instead, they put their money into improving infrastructure, education and salaries for workers in their own nations.
See Learning Objective 5: Identify and describe different sources of long-term financing.
Lenders may also require certain restrictions to force the firm to act responsibly.
See Learning Objective 5: Identify and describe different sources of long-term financing.
It is critical that students understand bonds are a form of debt issued by companies.
The terms debt, bond, and loan are all four letter words and basically mean the same thing.
Students should walk away from this discussion knowing that the government and private industry compete insofar as the sale of bonds to the investing public. The issue of investor security can easily be addressed here, as well as the differences in interest rates paid on specific bonds depending on the issuer. Students should understand that U.S. Government bonds are considered the safest investment in the bond market. There is a high probability that students will be familiar with U.S. Government Savings Bonds, and may in fact have received such a bond as a gift. They clearly need to understand the difference between such bonds and issues involving investments in corporate bonds.
See Learning Objective 5: Identify and describe different sources of long-term financing.
See Learning Objective 5: Identify and describe different sources of long-term financing.
This slide shows how venture capitalists assess the many pitches they receive all year.
Venture capitalists want to ensure that not only will they get their money back, but that they will also earn more than their investment.
Why is a question like “Will it be worth our money and effort?” important to venture capitalists? (VCs want to make sure there is a large return on their investment so they can make money and continue investing in other companies.)
See Learning Objective 5: Identify and describe different sources of long-term financing.
This slide is based on Figure 16.6.
Financial managers must evaluate the benefits of issuing debt or equity and then weigh those benefits with the drawbacks.
See Learning Objective 5: Identify and describe different sources of long-term financing.
See Learning Objective 5: Identify and describe different sources of long-term financing.
Financial managers must evaluate the benefits of issuing debt or equity and then weigh those benefits with the drawbacks.
See Learning Objective 5: Identify and describe different sources of long-term financing.
A company could issue and sell bonds or they could borrow from financial institutions and individuals.
The primary difference between debt financing and equity financing is that debt must be repaid at maturity while there is no obligation to repay equity financing. Interest must be paid on debt, while the company is under no obligation to issue dividends on equity financing. The interest paid is tax deductible, while dividends are not. Finally, debt holders do not have the right to vote on company matters, while equity holders usually do have voting rights.
A business can obtain equity financing from the sale of company stock, from retained earnings, or from venture capital firms.
Leverage is borrowing funds to invest in expansion, major asset purchases, or research and development. Firms use leverage in an effort to increase the firm’s profit.