This document provides a monthly project storyboard for the B636 Phase 1 project from June 2016. It consists of over 30 photos documenting the progression of construction from the initial site work and building structure through interior construction and installation of production equipment. The final photos show the completed expanded facility with finished mechanical and process systems in place.

1. June 2016
B636 Phase 1
Project Storyboard

2. B636 Aerial View Prior to Retrofit

3. Aerial view of 633 and 636 after 636 expansion June 2016

4. Breaking
Ground

5. Grading
and
Civil Work

6. Columns
go up

7. Structural Laydown Area

8. Structure Taking Form

9. Building Structure
and Shell

10. Parking Lot/Civil Work

11. The Roof

12. Interior
Demolition
and
Trenching
for Drain
Piping

13. Construction
Trailers

14. Building Shell

15. Exterior
Siding
Complete

16. Ductwork
and
High Piping
Installation
Starts

17. Interior Concrete is Poured

18. Tech Core Ductwork and Pipe Rack Installation Begins

19. Interior
Framing
and
Utility
Piping

20. Civil Work
for Switchgear 2

21. Pipe Rack Rigging

22. Mezzanine
and
First Floor
Interior
Views

23. Catwalk and Pipe Module Installation

24. Interior
Progress

25. Buffer Prep Module
Being Brought Inside

26. Interior
Progress
Views

27. Admin Area Under Construction

28. Admin Areas
Under
Construction

29. Completed
Admin Areas

30. IT Server Rooms & UPS Room

31. Air Handlers in
Mezzanine Installed

32. QC Lab Progress

33. QC Lab Casework Completed

34. Validation Lab

35. Production Equipment
being Set in Place

36. CIP Skids

37. Modules 3 & 4 being Put Together

38. Seed Reactors
and
Cell Culture
Hall Utility Panels

39. Interstitial
Space

40. Roof Exhaust
Fans and
Ductwork

41. Architectural Finishes
for Material Air Locks
and Clean Corridor

42. Bio-Waste Collection Tank
Construction

43. CUB Expansion Shell, WFI Still
Set in Place, Trenching for Drains

44. CUB Interior Progress

45. CUB Utility
Equipment
Installation

46. CUB WFI
and Pure Steam Generators

47. CUB Second Floor WFI Storage Tanks

48. Electrical
Glycol Tank

49. Process Glycol Tank
and Chiller
Installation - Tank
with and without
Insulation

50. Aerial View Expanded Building 636

51. Finished
Systems
compressd Air Carbon Filter
CIP Skids

52. Finished
Systems
Rocker Reactors Seed Reactors
Production Reactors

53. Finished
Systems
Technical Core
Column PackingChromatography Controller Skids

54. Confidentiality Notice
This file is private and may contain confidential and proprietary information. If you have received this file in error, please notify us and remove
it from your systme and note that you must not copy, distribute or take any action in reliance on it. Any unauthorized use or disclosure of the
contents of this file is not permitted and may be unlawful. AstraZeneca PLC, 2 Kingdom Street, London, W2 6BD, UK, T: +44(0)20 7604 8000,
F: +44 (0)20 7604 8151, www.astrazeneca.com